|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.547
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.503
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.460
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.449
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.430
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.401
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.377
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.293
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.290
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.261
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.247
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.234
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.227
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.223
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.221
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.215
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.211
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.193
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.189
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.189
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.186
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.185
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.184
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.179
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.177
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.172
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.155
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.154
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.149
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.147
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.142
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.133
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.131
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.128
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.123
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.120
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.119
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.116
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.116
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.111
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.111
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.108
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.106
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.100
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.099
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.098
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.097
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.097
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.095
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.095
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.095
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.094
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.094
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.093
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.090
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.086
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.084
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.082
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.081
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.078
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.078
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.077
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.077
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.077
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.076
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.075
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.075
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.075
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.075
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.074
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.074
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.074
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.074
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.074
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.074
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.072
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.072
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.071
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.071
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.070
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.070
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.070
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.070
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.069
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.067
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.067
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.066
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.066
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.065
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.065
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.065
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.065
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.065
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.065
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.064
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.064
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.063
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.063
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.063
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.061
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.061
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.061
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.060
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.060
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.060
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.060
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.059
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.058
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.058
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.057
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.057
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.057
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.056
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.056
|
Mouse |
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.055
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.055
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.054
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.053
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.053
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.053
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.053
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.051
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.051
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.050
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.050
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.050
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.050
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.049
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.049
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.049
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.049
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.048
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.048
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.048
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.048
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.048
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.048
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.047
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.047
|
Mouse |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.047
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.047
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.047
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.047
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.047
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.046
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.046
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.046
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.046
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.045
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.045
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.045
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.045
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.045
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.045
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.044
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.043
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.043
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.042
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.042
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.042
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.042
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.042
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.042
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.041
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.041
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.041
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.041
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.041
|
|
|
|
toll like receptor 9 signaling pathway
|
GO:0034162 |
6 |
0.041
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.041
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.040
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.040
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.040
|
Mouse |
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.040
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.040
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.040
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.040
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.040
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.039
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.039
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.039
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.039
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.039
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.038
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.038
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.038
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.038
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.038
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.037
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.037
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.037
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.037
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.037
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.037
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.037
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.037
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.037
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.037
|
Mouse |
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.036
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.036
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.036
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.036
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.036
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.036
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.036
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.036
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.036
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.036
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.035
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.035
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.035
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.035
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.035
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.035
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.035
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.035
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.035
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.034
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.034
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.034
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.034
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.034
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.033
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.033
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.033
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.033
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.033
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.033
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.033
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.033
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.033
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.032
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.032
|
Mouse |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.032
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.032
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.032
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.032
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.032
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.031
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.031
|
Mouse |
|
|
mast cell activation
|
GO:0045576 |
27 |
0.031
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.031
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.031
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.031
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.031
|
|
|
|
detection of other organism
|
GO:0098543 |
8 |
0.031
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.031
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.031
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.031
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.031
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.031
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.030
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.030
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.030
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.030
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.030
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.029
|
Mouse |
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.029
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.029
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.029
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.029
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.029
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.029
|
|
|
|
g protein coupled purinergic nucleotide receptor signaling pathway
|
GO:0035589 |
1 |
0.029
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.029
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.029
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.029
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.029
|
Mouse |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.029
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.029
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.029
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.028
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.028
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.028
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.028
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.028
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.028
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.028
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.028
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.028
|
|
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.028
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.028
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.028
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.028
|
Mouse |
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.028
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.028
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.028
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.027
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.027
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.027
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.027
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.027
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.027
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.027
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.027
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.027
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.026
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.026
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.026
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.026
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.026
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.026
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.026
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.026
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.026
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.026
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.026
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.026
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.025
|
Mouse |
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.025
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.025
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.025
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.025
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.025
|
Mouse |
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.025
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.025
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.025
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.025
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.025
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.025
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.025
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.025
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.025
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.025
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.024
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.024
|
Mouse |
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.024
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.024
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.024
|
Mouse |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.024
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.024
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.024
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.024
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.024
|
Mouse |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.024
|
|
|
|
response to host
|
GO:0075136 |
3 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.023
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.023
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.023
|
Mouse |
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.023
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.023
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.023
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.023
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.023
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.023
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.023
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.023
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.023
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.023
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.023
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.022
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.022
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.022
|
Mouse |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.022
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.022
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.022
|
Mouse |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.022
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.022
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.022
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.022
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.022
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.022
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.022
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.022
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.022
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.022
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.021
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.021
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.021
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.021
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.021
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.021
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.021
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.021
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.021
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.021
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.021
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.021
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.021
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.021
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.021
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.021
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.021
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.020
|
Mouse |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.020
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.020
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.020
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.020
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.020
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.020
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.020
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.020
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.020
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.020
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.020
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.020
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.020
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.020
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.020
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.020
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.020
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.020
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.020
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.020
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.020
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.020
|
Mouse |
|
|
axon guidance
|
GO:0007411 |
141 |
0.019
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.019
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.019
|
Mouse |
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.019
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.019
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.019
|
Mouse |
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.019
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.019
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.019
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.019
|
Mouse |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.019
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.019
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.019
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.019
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.019
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.019
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.018
|
Mouse |
|
|
response to bacterial lipoprotein
|
GO:0032493 |
4 |
0.018
|
|
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.018
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.018
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.018
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.018
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.018
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.018
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.018
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.018
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.018
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.018
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.018
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.018
|
|
|
|
negative regulation of mast cell degranulation
|
GO:0043305 |
4 |
0.018
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.018
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.018
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
2 |
0.018
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.018
|
|
|
|
negative regulation of regulated secretory pathway
|
GO:1903306 |
7 |
0.018
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.018
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.018
|
Human Mouse |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.018
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.018
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.018
|
|
|
|
response to host immune response
|
GO:0052572 |
3 |
0.018
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.018
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.018
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.018
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.018
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.018
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.017
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.017
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.017
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.017
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.017
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.017
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.017
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.017
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.017
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.017
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.017
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.017
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.017
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.017
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.017
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.017
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.017
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.017
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.017
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.017
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.017
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.017
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.017
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.017
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.017
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.017
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.017
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.017
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.016
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.016
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.016
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.016
|
|
|
|
negative regulation of nlrp3 inflammasome complex assembly
|
GO:1900226 |
2 |
0.016
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.016
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.016
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.016
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.016
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.016
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.016
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.016
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.016
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.016
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.016
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.016
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.016
|
|
