Mus musculus

0 known processes

Wdr45

WD repeat domain 45

(Aliases: Wdrx1,C79260,DXImx38e,Sfc19,JM5)

Wdr45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.522
autophagy GO:0006914 45 0.157
Human
protein catabolic process GO:0030163 221 0.118
cellular amino acid metabolic process GO:0006520 103 0.116
regulation of cellular amino acid metabolic process GO:0006521 5 0.113
response to extracellular stimulus GO:0009991 127 0.088
cellular ketone metabolic process GO:0042180 84 0.086
macroautophagy GO:0016236 21 0.085
cofactor metabolic process GO:0051186 80 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.080
dna metabolic process GO:0006259 303 0.078
macromolecule catabolic process GO:0009057 281 0.077
protein processing GO:0016485 163 0.072
cation transport GO:0006812 399 0.066
protein modification by small protein conjugation or removal GO:0070647 207 0.063
cellular amine metabolic process GO:0044106 44 0.063
dephosphorylation GO:0016311 129 0.062
negative regulation of cell cycle GO:0045786 123 0.061
protein maturation GO:0051604 176 0.060
cellular lipid metabolic process GO:0044255 323 0.059
cellular response to external stimulus GO:0071496 88 0.058
membrane fusion GO:0061025 38 0.055
cellular response to extracellular stimulus GO:0031668 81 0.054
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.054
small molecule catabolic process GO:0044282 71 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.050
regulation of cellular protein catabolic process GO:1903362 61 0.049
amine metabolic process GO:0009308 45 0.048
nitrogen compound transport GO:0071705 271 0.047
regulation of cell cycle GO:0051726 281 0.047
cellular lipid catabolic process GO:0044242 52 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
protein modification by small protein conjugation GO:0032446 187 0.044
mitotic cell cycle process GO:1903047 159 0.043
mitochondrion degradation GO:0000422 3 0.041
negative regulation of protein metabolic process GO:0051248 282 0.040
regulation of binding GO:0051098 111 0.040
cellular macromolecule catabolic process GO:0044265 206 0.040
negative regulation of cellular amine metabolic process GO:0033239 1 0.040
negative regulation of cellular component organization GO:0051129 194 0.040
regulation of protein maturation GO:1903317 96 0.039
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.039
positive regulation of dopamine secretion GO:0033603 2 0.038
regulation of intracellular transport GO:0032386 159 0.037
spermatogenesis GO:0007283 284 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
regulation of protein localization GO:0032880 231 0.036
cellular response to nutrient levels GO:0031669 64 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
apoptotic signaling pathway GO:0097190 306 0.035
male gamete generation GO:0048232 285 0.034
negative regulation of cell proliferation GO:0008285 296 0.034
regulation of homeostatic process GO:0032844 182 0.033
organelle fusion GO:0048284 28 0.033
positive regulation of tor signaling GO:0032008 3 0.032
response to nutrient levels GO:0031667 109 0.032
negative regulation of protein modification process GO:0031400 163 0.031
glucose homeostasis GO:0042593 128 0.030
protein ubiquitination GO:0016567 171 0.030
modification dependent protein catabolic process GO:0019941 133 0.029
membrane organization GO:0061024 245 0.029
mitotic cell cycle GO:0000278 195 0.029
lateral inhibition GO:0046331 1 0.028
regulation of cellular response to stress GO:0080135 159 0.028
generation of precursor metabolites and energy GO:0006091 103 0.028
ossification GO:0001503 216 0.028
cellular response to starvation GO:0009267 57 0.027
positive regulation of cell death GO:0010942 224 0.027
regulation of mitotic cell cycle GO:0007346 126 0.027
cellular protein catabolic process GO:0044257 155 0.027
positive regulation of homeostatic process GO:0032846 64 0.027
defense response to other organism GO:0098542 197 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
modification dependent macromolecule catabolic process GO:0043632 133 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
water transport GO:0006833 12 0.026
ubiquitin dependent protein catabolic process GO:0006511 129 0.026
nucleotide metabolic process GO:0009117 332 0.026
monocarboxylic acid catabolic process GO:0072329 27 0.025
transcription from rna polymerase iii promoter GO:0006383 3 0.025
reactive nitrogen species metabolic process GO:2001057 0 0.025
positive regulation of catecholamine secretion GO:0033605 2 0.025
negative regulation of protein processing GO:0010955 79 0.025
negative regulation of cellular catabolic process GO:0031330 47 0.025
regulation of cell cycle phase transition GO:1901987 77 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
regulation of protein transport GO:0051223 163 0.023
lipid modification GO:0030258 65 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
regulation of secretion GO:0051046 274 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
regulation of hormone levels GO:0010817 211 0.022
regulation of ossification GO:0030278 112 0.022
negative regulation of apoptotic signaling pathway GO:2001234 104 0.021
regulation of organelle organization GO:0033043 289 0.021
visual behavior GO:0007632 45 0.021
organic acid catabolic process GO:0016054 51 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
homeostasis of number of cells GO:0048872 210 0.021
negative regulation of mitotic cell cycle GO:0045930 58 0.021
response to starvation GO:0042594 65 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
fatty acid oxidation GO:0019395 28 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
very long chain fatty acid catabolic process GO:0042760 2 0.020
peptidyl amino acid modification GO:0018193 336 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
maintenance of location GO:0051235 89 0.020
regulation of cell cycle process GO:0010564 160 0.020
regulation of intracellular protein transport GO:0033157 82 0.020
regulation of protein processing GO:0070613 96 0.020
ras protein signal transduction GO:0007265 77 0.020
negative regulation of protein maturation GO:1903318 79 0.019
glucan metabolic process GO:0044042 32 0.019
regulation of mapk cascade GO:0043408 248 0.019
regulation of secretion by cell GO:1903530 249 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
negative regulation of proteolysis GO:0045861 74 0.019
carboxylic acid catabolic process GO:0046395 51 0.019
retrograde transport endosome to golgi GO:0042147 2 0.019
cellular response to cytokine stimulus GO:0071345 189 0.018
regulation of body fluid levels GO:0050878 162 0.018
cation transmembrane transport GO:0098655 266 0.018
regulation of protein catabolic process GO:0042176 108 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
t cell activation GO:0042110 289 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
response to organic cyclic compound GO:0014070 198 0.018
endomembrane system organization GO:0010256 147 0.018
regulation of dephosphorylation GO:0035303 18 0.017
germ line stem cell division GO:0042078 2 0.017
negative regulation of cell cycle phase transition GO:1901988 48 0.017
negative regulation of glycogen biosynthetic process GO:0045719 1 0.017
regulation of transferase activity GO:0051338 263 0.017
positive regulation of secretion GO:0051047 130 0.017
sperm motility GO:0030317 47 0.017
lipid biosynthetic process GO:0008610 179 0.017
alpha amino acid metabolic process GO:1901605 59 0.017
cellular response to oxidative stress GO:0034599 76 0.017
immune effector process GO:0002252 321 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
vacuole organization GO:0007033 38 0.016
cytoplasmic transport GO:0016482 234 0.016
mitotic cytokinesis GO:0000281 4 0.016
regulation of membrane potential GO:0042391 192 0.016
neuron death GO:0070997 154 0.016
defense response to bacterium GO:0042742 119 0.016
energy derivation by oxidation of organic compounds GO:0015980 77 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
response to organonitrogen compound GO:0010243 246 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
establishment of protein localization to peroxisome GO:0072663 4 0.015
rab protein signal transduction GO:0032482 1 0.015
negative regulation of cellular protein catabolic process GO:1903363 22 0.015
regulation of osteoblast differentiation GO:0045667 67 0.015
cellular chemical homeostasis GO:0055082 215 0.015
regulation of proteolysis GO:0030162 164 0.015
positive regulation of macroautophagy GO:0016239 3 0.015
renal water transport GO:0003097 6 0.015
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.015
cell type specific apoptotic process GO:0097285 268 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
interspecies interaction between organisms GO:0044419 83 0.015
mitochondrion organization GO:0007005 134 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
divalent metal ion transport GO:0070838 172 0.014
methylation GO:0032259 134 0.014
extracellular structure organization GO:0043062 148 0.014
response to endoplasmic reticulum stress GO:0034976 53 0.014
metal ion homeostasis GO:0055065 189 0.014
positive regulation of protein modification process GO:0031401 299 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.014
response to light stimulus GO:0009416 135 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
monoamine transport GO:0015844 33 0.014
regulation of ion transport GO:0043269 215 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
divalent inorganic cation transport GO:0072511 178 0.013
negative regulation of cytokine production GO:0001818 84 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.013
regulation of kinase activity GO:0043549 249 0.013
protein localization to organelle GO:0033365 185 0.013
ear development GO:0043583 200 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
dna recombination GO:0006310 92 0.013
anatomical structure homeostasis GO:0060249 145 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
response to oxygen levels GO:0070482 62 0.013
phospholipid metabolic process GO:0006644 87 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
carbohydrate homeostasis GO:0033500 128 0.012
sequestering of metal ion GO:0051238 19 0.012
protein secretion GO:0009306 111 0.012
negative regulation of growth GO:0045926 99 0.012
regulation of peptide transport GO:0090087 91 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
organelle fission GO:0048285 170 0.012
regulation of hydrolase activity GO:0051336 246 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
negative regulation of nervous system development GO:0051961 156 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
digestive tract morphogenesis GO:0048546 147 0.012
response to radiation GO:0009314 165 0.012
biomineral tissue development GO:0031214 64 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
action potential GO:0001508 78 0.012
microtubule based process GO:0007017 236 0.012
protein kinase b signaling GO:0043491 74 0.012
modification by host of symbiont morphology or physiology GO:0051851 12 0.012
sensory perception GO:0007600 245 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
substantia nigra development GO:0021762 2 0.011
negative regulation of protein transport GO:0051224 46 0.011
neuron apoptotic process GO:0051402 142 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
cell division GO:0051301 120 0.011
chemotaxis GO:0006935 247 0.011
endocytosis GO:0006897 168 0.011
mitochondrial dna metabolic process GO:0032042 13 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
cellular homeostasis GO:0019725 240 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
vitamin d3 metabolic process GO:0070640 3 0.011
lipid catabolic process GO:0016042 69 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
negative regulation of organelle organization GO:0010639 90 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
mapk cascade GO:0000165 281 0.011
aromatic compound catabolic process GO:0019439 286 0.011
cellular glucose homeostasis GO:0001678 52 0.011
skin development GO:0043588 220 0.011
sensory perception of pain GO:0019233 47 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
rhythmic process GO:0048511 174 0.011
regulation of biomineral tissue development GO:0070167 33 0.010
response to growth factor GO:0070848 198 0.010
negative regulation of mitochondrion organization GO:0010823 9 0.010
positive regulation of mitochondrial fission GO:0090141 2 0.010
muscle cell differentiation GO:0042692 261 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
hormone secretion GO:0046879 128 0.010
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.010
multicellular organismal signaling GO:0035637 91 0.010
isoprenoid metabolic process GO:0006720 29 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
sterol homeostasis GO:0055092 45 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
calcium ion homeostasis GO:0055074 127 0.010
regulation of protein binding GO:0043393 60 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
innate immune response GO:0045087 157 0.010
muscle tissue development GO:0060537 308 0.010
cytokine production GO:0001816 319 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010

Wdr45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
nervous system disease DOID:863 0 0.016
central nervous system disease DOID:331 0 0.016
disease of anatomical entity DOID:7 0 0.016
inherited metabolic disorder DOID:655 0 0.013