Mus musculus

12 known processes

Lnx2

ligand of numb-protein X 2

(Aliases: 9630046H24,AW209022)

Lnx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuroblast division in subventricular zone GO:0021849 2 0.058
cellular ketone metabolic process GO:0042180 84 0.056
asymmetric stem cell division GO:0098722 3 0.053
covalent chromatin modification GO:0016569 163 0.052
cellular amino acid metabolic process GO:0006520 103 0.050
cellular amine metabolic process GO:0044106 44 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.044
organic anion transport GO:0015711 137 0.044
apoptotic signaling pathway GO:0097190 306 0.043
small gtpase mediated signal transduction GO:0007264 97 0.042
regulation of organelle organization GO:0033043 289 0.041
negative regulation of cell proliferation GO:0008285 296 0.040
negative regulation of molecular function GO:0044092 258 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.037
glycosyl compound catabolic process GO:1901658 206 0.035
ras protein signal transduction GO:0007265 77 0.035
anion transport GO:0006820 177 0.035
respiratory system development GO:0060541 190 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
cellular macromolecule catabolic process GO:0044265 206 0.034
Mouse
glycosyl compound metabolic process GO:1901657 246 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
asymmetric neuroblast division GO:0055059 1 0.032
negative regulation of phosphate metabolic process GO:0045936 184 0.032
negative regulation of phosphorylation GO:0042326 166 0.032
transmembrane transport GO:0055085 412 0.032
respiratory tube development GO:0030323 167 0.031
cell cell junction organization GO:0045216 72 0.031
nucleoside metabolic process GO:0009116 246 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
cellular lipid metabolic process GO:0044255 323 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
homeostasis of number of cells GO:0048872 210 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
peptidyl amino acid modification GO:0018193 336 0.029
cell junction organization GO:0034330 77 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
amine metabolic process GO:0009308 45 0.029
aromatic compound catabolic process GO:0019439 286 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
heterocycle catabolic process GO:0046700 280 0.029
carbohydrate metabolic process GO:0005975 230 0.028
lung development GO:0030324 164 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
regulation of protein localization GO:0032880 231 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
regulation of hydrolase activity GO:0051336 246 0.028
positive regulation of protein modification process GO:0031401 299 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
muscle cell differentiation GO:0042692 261 0.027
purine containing compound metabolic process GO:0072521 311 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
myeloid cell differentiation GO:0030099 233 0.027
purine containing compound catabolic process GO:0072523 213 0.027
regulation of cellular catabolic process GO:0031329 242 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
regulation of mapk cascade GO:0043408 248 0.026
cation transmembrane transport GO:0098655 266 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
cytokine production GO:0001816 319 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.025
muscle tissue development GO:0060537 308 0.025
intracellular protein transport GO:0006886 204 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
striated muscle tissue development GO:0014706 293 0.025
forebrain development GO:0030900 302 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
regulation of cell activation GO:0050865 289 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
myeloid cell homeostasis GO:0002262 114 0.024
regulation of cell migration GO:0030334 219 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
regulation of t cell activation GO:0050863 170 0.024
organophosphate catabolic process GO:0046434 232 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
endomembrane system organization GO:0010256 147 0.023
ion transmembrane transport GO:0034220 361 0.023
chromatin modification GO:0016568 187 0.023
protein ubiquitination GO:0016567 171 0.023
Mouse
macromolecule catabolic process GO:0009057 281 0.023
Mouse
regulation of transferase activity GO:0051338 263 0.023
nucleotide catabolic process GO:0009166 217 0.023
lipid transport GO:0006869 98 0.023
t cell activation GO:0042110 289 0.023
nucleotide metabolic process GO:0009117 332 0.023
response to radiation GO:0009314 165 0.022
Fly
purine nucleoside catabolic process GO:0006152 205 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
tube formation GO:0035148 140 0.022
endocytosis GO:0006897 168 0.022
lipid biosynthetic process GO:0008610 179 0.022
neural precursor cell proliferation GO:0061351 121 0.022
nitrogen compound transport GO:0071705 271 0.022
regulation of defense response GO:0031347 233 0.022
histone modification GO:0016570 159 0.021
cation transport GO:0006812 399 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
Mouse
positive regulation of apoptotic process GO:0043065 217 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
positive regulation of cell development GO:0010720 237 0.021
regulation of cell motility GO:2000145 236 0.021
sterol homeostasis GO:0055092 45 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
regulation of asymmetric cell division GO:0009786 4 0.021
cell division GO:0051301 120 0.021
cell adhesion GO:0007155 329 0.021
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.021
Mouse
regulation of cytokine production GO:0001817 266 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
protein targeting GO:0006605 143 0.020
positive regulation of nervous system development GO:0051962 221 0.020
lipid localization GO:0010876 126 0.020
leukocyte proliferation GO:0070661 172 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
nucleoside catabolic process GO:0009164 206 0.020
membrane organization GO:0061024 245 0.020
mapk cascade GO:0000165 281 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
Mouse
inflammatory response GO:0006954 244 0.019
stem cell proliferation GO:0072089 117 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
chromatin organization GO:0006325 206 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
negative regulation of protein modification process GO:0031400 163 0.019
regulation of protein kinase activity GO:0045859 232 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
cell type specific apoptotic process GO:0097285 268 0.019
positive regulation of interleukin 8 production GO:0032757 2 0.019
fat cell differentiation GO:0045444 160 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
Mouse
immune effector process GO:0002252 321 0.018
ossification GO:0001503 216 0.018
compound eye development GO:0048749 1 0.018
negative regulation of immune system process GO:0002683 209 0.018
urogenital system development GO:0001655 261 0.018
positive regulation of organelle organization GO:0010638 128 0.018
regulation of neuron differentiation GO:0045664 281 0.018
renal system development GO:0072001 225 0.018
actin cytoskeleton organization GO:0030036 220 0.018
cellular protein complex assembly GO:0043623 116 0.018
leukocyte differentiation GO:0002521 342 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
stem cell differentiation GO:0048863 268 0.018
rna interference GO:0016246 2 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
exocytosis GO:0006887 121 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of organ morphogenesis GO:2000027 144 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
response to organonitrogen compound GO:0010243 246 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
cytoplasmic transport GO:0016482 234 0.017
rho protein signal transduction GO:0007266 32 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
skeletal system development GO:0001501 356 0.017
actin filament organization GO:0007015 113 0.017
regulation of anatomical structure size GO:0090066 178 0.017
mitotic cell cycle GO:0000278 195 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
regulation of secretion GO:0051046 274 0.017
camera type eye development GO:0043010 266 0.017
synaptic transmission GO:0007268 329 0.017
response to growth factor GO:0070848 198 0.017
muscle cell fate specification GO:0042694 1 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
myotube differentiation GO:0014902 105 0.016
microtubule based process GO:0007017 236 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
regulation of interleukin 8 production GO:0032677 3 0.016
protein localization to membrane GO:0072657 108 0.016
regulation of cell projection organization GO:0031344 206 0.016
nuclear transport GO:0051169 139 0.016
organophosphate ester transport GO:0015748 28 0.016
maintenance of location GO:0051235 89 0.016
gtp catabolic process GO:0006184 143 0.016
cellular protein catabolic process GO:0044257 155 0.016
Mouse
axonogenesis GO:0007409 274 0.016
divalent metal ion transport GO:0070838 172 0.016
positive regulation of cell death GO:0010942 224 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
telencephalon development GO:0021537 186 0.016
mitochondrion organization GO:0007005 134 0.016
oxidation reduction process GO:0055114 342 0.016
gtp metabolic process GO:0046039 144 0.016
dephosphorylation GO:0016311 129 0.016
regionalization GO:0003002 337 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.015
regulation of secretion by cell GO:1903530 249 0.015
negative regulation of cell development GO:0010721 169 0.015
gland development GO:0048732 330 0.015
wnt signaling pathway GO:0016055 188 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
multicellular organismal signaling GO:0035637 91 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
erythrocyte differentiation GO:0030218 88 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
divalent inorganic cation transport GO:0072511 178 0.015
stem cell development GO:0048864 219 0.015
fatty acid metabolic process GO:0006631 121 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
methylation GO:0032259 134 0.015
cell substrate adhesion GO:0031589 130 0.015
sensory perception GO:0007600 245 0.015
Fly
actin polymerization or depolymerization GO:0008154 54 0.015
regulation of system process GO:0044057 200 0.015
negative regulation of organelle organization GO:0010639 90 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
actin filament based movement GO:0030048 23 0.015
cellular chemical homeostasis GO:0055082 215 0.015
plasma membrane organization GO:0007009 90 0.015
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of cell cycle GO:0051726 281 0.014
epithelial tube formation GO:0072175 130 0.014
positive regulation of cell motility GO:2000147 116 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
cellular homeostasis GO:0019725 240 0.014
glycerolipid metabolic process GO:0046486 122 0.014
carbohydrate homeostasis GO:0033500 128 0.014
lymphocyte proliferation GO:0046651 164 0.014
cholesterol homeostasis GO:0042632 44 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
response to light stimulus GO:0009416 135 0.014
Fly
interleukin 8 production GO:0032637 4 0.014
glycoprotein metabolic process GO:0009100 116 0.014
notch signaling pathway GO:0007219 71 0.014
mitotic cell cycle process GO:1903047 159 0.014
cation homeostasis GO:0055080 212 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
t cell proliferation GO:0042098 120 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
innate immune response GO:0045087 157 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.013
organic acid transport GO:0015849 101 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
male gamete generation GO:0048232 285 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
spermatogenesis GO:0007283 284 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
lipid homeostasis GO:0055088 63 0.013
protein catabolic process GO:0030163 221 0.013
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
negative regulation of transferase activity GO:0051348 85 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
b cell activation GO:0042113 161 0.013
regulation of osteoblast differentiation GO:0045667 67 0.013
morphogenesis of a polarized epithelium GO:0001738 37 0.013
actin filament polymerization GO:0030041 44 0.013
cytokinetic process GO:0032506 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
organelle fission GO:0048285 170 0.013
germ cell development GO:0007281 185 0.013
cognition GO:0050890 149 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
Fly
rac protein signal transduction GO:0016601 13 0.013
learning or memory GO:0007611 148 0.013
carboxylic acid transport GO:0046942 100 0.013
regulation of t cell proliferation GO:0042129 92 0.013
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of cellular response to stress GO:0080135 159 0.012
organelle localization GO:0051640 179 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
nuclear division GO:0000280 158 0.012
regulation of kinase activity GO:0043549 249 0.012
protein localization to nucleus GO:0034504 121 0.012
blood vessel morphogenesis GO:0048514 285 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
action potential GO:0001508 78 0.012
monosaccharide metabolic process GO:0005996 106 0.012
protein polymerization GO:0051258 57 0.012
oocyte construction GO:0007308 2 0.012
protein maturation GO:0051604 176 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
neural tube formation GO:0001841 108 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
organic hydroxy compound transport GO:0015850 93 0.012
macromolecule methylation GO:0043414 120 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.012
glycerolipid biosynthetic process GO:0045017 50 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of transmembrane transport GO:0034762 128 0.012
gliogenesis GO:0042063 141 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
negative regulation of cell activation GO:0050866 111 0.012
response to lipopolysaccharide GO:0032496 128 0.012
defense response to other organism GO:0098542 197 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of cell adhesion GO:0030155 154 0.012
dna metabolic process GO:0006259 303 0.012
blood circulation GO:0008015 195 0.011
positive regulation of t cell activation GO:0050870 101 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
apical constriction GO:0003383 4 0.011
cellular ion homeostasis GO:0006873 165 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
single organism cell adhesion GO:0098602 156 0.011
small molecule biosynthetic process GO:0044283 132 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of cellular component size GO:0032535 121 0.011
regulation of homeostatic process GO:0032844 182 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
muscle cell development GO:0055001 133 0.011
protein processing GO:0016485 163 0.011
cellularization GO:0007349 1 0.011
positive regulation of cytokine production GO:0001819 174 0.011
glucose homeostasis GO:0042593 128 0.011
kidney development GO:0001822 213 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
neuron death GO:0070997 154 0.011
midgut development GO:0007494 4 0.011
regulation of ossification GO:0030278 112 0.011
cell fate commitment GO:0045165 210 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
synapse organization GO:0050808 125 0.011
regulation of hormone levels GO:0010817 211 0.011
transmission of nerve impulse GO:0019226 76 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
positive regulation of defense response GO:0031349 124 0.011
oocyte axis specification GO:0007309 2 0.011
mrna metabolic process GO:0016071 84 0.011
activation of immune response GO:0002253 138 0.011
cellular response to lipid GO:0071396 145 0.011
neuron apoptotic process GO:0051402 142 0.011
protein localization to organelle GO:0033365 185 0.011
lateral inhibition GO:0046331 1 0.011
membrane tubulation GO:0097320 4 0.011
immune response activating signal transduction GO:0002757 116 0.011
developmental maturation GO:0021700 193 0.011
localization within membrane GO:0051668 4 0.011
regulation of chromatin organization GO:1902275 57 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
negative regulation of nervous system development GO:0051961 156 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
positive regulation of cell migration GO:0030335 109 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
primary neural tube formation GO:0014020 95 0.010
wound healing GO:0042060 157 0.010
mitochondrion distribution GO:0048311 4 0.010
glucose metabolic process GO:0006006 92 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of actin filament based process GO:0032970 99 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
response to peptide GO:1901652 136 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
negative regulation of cholesterol transport GO:0032375 4 0.010
multicellular organism growth GO:0035264 161 0.010
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.010
primitive erythrocyte differentiation GO:0060319 3 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
cell growth GO:0016049 130 0.010
lymphocyte differentiation GO:0030098 242 0.010
positive regulation of kinase activity GO:0033674 155 0.010
calcium ion homeostasis GO:0055074 127 0.010
response to organic cyclic compound GO:0014070 198 0.010
sulfur compound metabolic process GO:0006790 100 0.010
skin development GO:0043588 220 0.010
skeletal system morphogenesis GO:0048705 203 0.010
leukocyte mediated immunity GO:0002443 174 0.010

Lnx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.026
disease of anatomical entity DOID:7 0 0.026
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.025
organ system cancer DOID:0050686 0 0.025
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.018
hematopoietic system disease DOID:74 0 0.015
connective tissue disease DOID:65 0 0.015
cardiovascular system disease DOID:1287 0 0.013
disease of metabolism DOID:0014667 0 0.012
sensory system disease DOID:0050155 0 0.012
bone disease DOID:0080001 0 0.011
immune system cancer DOID:0060083 0 0.010
hematologic cancer DOID:2531 0 0.010