Mus musculus

67 known processes

Gm2a

GM2 ganglioside activator protein

(Aliases: SAP-3,AA408702,AW215435,GM2-AP)

Gm2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.342
leukocyte mediated cytotoxicity GO:0001909 62 0.293
myosin filament assembly GO:0031034 2 0.088
antigen processing and presentation of peptide antigen GO:0048002 29 0.073
organelle assembly GO:0070925 177 0.073
lymphocyte mediated immunity GO:0002449 139 0.057
myosin filament organization GO:0031033 3 0.057
organonitrogen compound catabolic process GO:1901565 264 0.056
sphingolipid metabolic process GO:0006665 45 0.056
t cell activation GO:0042110 289 0.054
glycerolipid metabolic process GO:0046486 122 0.050
metal ion homeostasis GO:0055065 189 0.047
lytic vacuole organization GO:0080171 21 0.046
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.045
cell killing GO:0001906 67 0.044
reactive oxygen species biosynthetic process GO:1903409 8 0.043
cellular amino acid metabolic process GO:0006520 103 0.043
lipid biosynthetic process GO:0008610 179 0.043
carbohydrate derivative catabolic process GO:1901136 231 0.042
glycosyl compound catabolic process GO:1901658 206 0.042
lysosome organization GO:0007040 21 0.041
oxidation reduction process GO:0055114 342 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
ion transmembrane transport GO:0034220 361 0.041
lipid localization GO:0010876 126 0.040
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.039
cellular amide metabolic process GO:0043603 58 0.039
sphingolipid biosynthetic process GO:0030148 26 0.039
hormone metabolic process GO:0042445 86 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.039
heterocycle catabolic process GO:0046700 280 0.038
regulation of cellular catabolic process GO:0031329 242 0.038
striated muscle myosin thick filament assembly GO:0071688 1 0.038
cell adhesion GO:0007155 329 0.038
amine metabolic process GO:0009308 45 0.038
cation homeostasis GO:0055080 212 0.037
transition metal ion transport GO:0000041 38 0.037
antigen processing and presentation of exogenous antigen GO:0019884 26 0.036
adaptive immune response GO:0002250 155 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.035
macromolecule catabolic process GO:0009057 281 0.035
actin cytoskeleton organization GO:0030036 220 0.035
aromatic compound catabolic process GO:0019439 286 0.035
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.035
nucleotide metabolic process GO:0009117 332 0.034
t cell mediated cytotoxicity GO:0001913 26 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.033
transmembrane transport GO:0055085 412 0.033
antigen processing and presentation GO:0019882 47 0.033
membrane lipid biosynthetic process GO:0046467 32 0.032
cellular protein complex assembly GO:0043623 116 0.032
positive regulation of lymphocyte activation GO:0051251 140 0.031
response to organic cyclic compound GO:0014070 198 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
lipid transport GO:0006869 98 0.030
reactive nitrogen species metabolic process GO:2001057 0 0.030
positive regulation of apoptotic signaling pathway GO:2001235 95 0.030
membrane lipid metabolic process GO:0006643 53 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
nucleoside catabolic process GO:0009164 206 0.029
positive regulation of innate immune response GO:0045089 80 0.029
apoptotic signaling pathway GO:0097190 306 0.029
cellular component assembly involved in morphogenesis GO:0010927 139 0.029
sulfur compound metabolic process GO:0006790 100 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
purine nucleoside metabolic process GO:0042278 241 0.027
endocytosis GO:0006897 168 0.027
organic anion transport GO:0015711 137 0.027
cellular amine metabolic process GO:0044106 44 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
nucleoside metabolic process GO:0009116 246 0.027
angiogenesis GO:0001525 201 0.027
regulation of hydrolase activity GO:0051336 246 0.027
monocarboxylic acid metabolic process GO:0032787 191 0.027
regulation of lymphocyte activation GO:0051249 240 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.026
fatty acid metabolic process GO:0006631 121 0.025
alcohol metabolic process GO:0006066 116 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
cation transport GO:0006812 399 0.025
regulation of t cell activation GO:0050863 170 0.025
regulation of transferase activity GO:0051338 263 0.025
cellular homeostasis GO:0019725 240 0.024
glycosphingolipid catabolic process GO:0046479 5 0.024
ceramide metabolic process GO:0006672 31 0.024
response to peptide GO:1901652 136 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
carbohydrate metabolic process GO:0005975 230 0.024
ribonucleoside catabolic process GO:0042454 206 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
monosaccharide metabolic process GO:0005996 106 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
leukocyte mediated immunity GO:0002443 174 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
maintenance of location GO:0051235 89 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.022
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.022
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.022
amino acid transport GO:0006865 61 0.022
cellular lipid metabolic process GO:0044255 323 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
triglyceride metabolic process GO:0006641 51 0.022
regulation of cell activation GO:0050865 289 0.022
glycoprotein metabolic process GO:0009100 116 0.022
lung development GO:0030324 164 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
respiratory tube development GO:0030323 167 0.021
carboxylic acid transport GO:0046942 100 0.021
negative regulation of cell activation GO:0050866 111 0.021
anion transport GO:0006820 177 0.021
ceramide biosynthetic process GO:0046513 20 0.021
skeletal system development GO:0001501 356 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.020
lateral inhibition GO:0046331 1 0.020
natural killer cell mediated immunity GO:0002228 29 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
sterol metabolic process GO:0016125 58 0.020
nucleotide catabolic process GO:0009166 217 0.020
carbohydrate homeostasis GO:0033500 128 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
organic acid transport GO:0015849 101 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
lymphocyte proliferation GO:0046651 164 0.020
membrane organization GO:0061024 245 0.020
inflammatory response GO:0006954 244 0.020
purine containing compound metabolic process GO:0072521 311 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
neuronal action potential GO:0019228 54 0.020
cation transmembrane transport GO:0098655 266 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
nucleoside monophosphate metabolic process GO:0009123 85 0.019
neutral lipid metabolic process GO:0006638 57 0.019
respiratory system development GO:0060541 190 0.019
ear development GO:0043583 200 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
hexose metabolic process GO:0019318 98 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
regulation of adaptive immune response GO:0002819 90 0.018
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.018
protein catabolic process GO:0030163 221 0.018
regulation of leukocyte mediated immunity GO:0002703 104 0.018
male gamete generation GO:0048232 285 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
lipid catabolic process GO:0016042 69 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
t cell mediated immunity GO:0002456 50 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
rho protein signal transduction GO:0007266 32 0.017
organic acid catabolic process GO:0016054 51 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
lipid modification GO:0030258 65 0.017
peptidyl amino acid modification GO:0018193 336 0.017
cellular ketone metabolic process GO:0042180 84 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
response to organonitrogen compound GO:0010243 246 0.016
immune effector process GO:0002252 321 0.016
organophosphate catabolic process GO:0046434 232 0.016
macromolecule glycosylation GO:0043413 55 0.016
small molecule catabolic process GO:0044282 71 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
regulation of hormone levels GO:0010817 211 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
small molecule biosynthetic process GO:0044283 132 0.016
innate immune response GO:0045087 157 0.016
intracellular cholesterol transport GO:0032367 3 0.016
cellular chemical homeostasis GO:0055082 215 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
response to extracellular stimulus GO:0009991 127 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
dephosphorylation GO:0016311 129 0.016
iron ion import into cell GO:0097459 4 0.015
muscle cell differentiation GO:0042692 261 0.015
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.015
vacuole organization GO:0007033 38 0.015
cellular modified amino acid metabolic process GO:0006575 63 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
locomotory behavior GO:0007626 195 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
multicellular organismal iron ion homeostasis GO:0060586 8 0.015
nitrogen compound transport GO:0071705 271 0.015
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 14 0.014
intracellular protein transport GO:0006886 204 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
organic hydroxy compound transport GO:0015850 93 0.014
regulation of membrane potential GO:0042391 192 0.014
single organism cell adhesion GO:0098602 156 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
sodium ion transmembrane transport GO:0035725 49 0.014
lipid homeostasis GO:0055088 63 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
atp catabolic process GO:0006200 55 0.014
regulation of defense response GO:0031347 233 0.014
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.014
regulation of t cell mediated cytotoxicity GO:0001914 18 0.014
epithelial cell proliferation GO:0050673 174 0.014
cellular lipid catabolic process GO:0044242 52 0.014
glycosylceramide metabolic process GO:0006677 4 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
facioacoustic ganglion development GO:1903375 3 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
sphingolipid catabolic process GO:0030149 7 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
organophosphate ester transport GO:0015748 28 0.013
natural killer cell mediated cytotoxicity GO:0042267 29 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
intracellular sterol transport GO:0032366 3 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
multicellular organismal signaling GO:0035637 91 0.013
positive regulation of protein modification process GO:0031401 299 0.013
regulation of system process GO:0044057 200 0.013
actomyosin structure organization GO:0031032 56 0.013
response to nutrient levels GO:0031667 109 0.013
multicellular organism growth GO:0035264 161 0.013
sequestering of metal ion GO:0051238 19 0.013
cellular ion homeostasis GO:0006873 165 0.013
fat cell differentiation GO:0045444 160 0.013
glucose homeostasis GO:0042593 128 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
wound healing GO:0042060 157 0.013
organelle localization GO:0051640 179 0.012
regulation of proteolysis GO:0030162 164 0.012
intracellular lipid transport GO:0032365 3 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.012
lymphocyte differentiation GO:0030098 242 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.012
mrna metabolic process GO:0016071 84 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
collagen metabolic process GO:0032963 17 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.012
cellular response to lipid GO:0071396 145 0.012
synaptic vesicle localization GO:0097479 59 0.012
regulation of kinase activity GO:0043549 249 0.012
regulation of peptidase activity GO:0052547 96 0.012
alpha beta t cell activation GO:0046631 91 0.012
calcium ion transport GO:0006816 159 0.012
action potential GO:0001508 78 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
positive regulation of t cell activation GO:0050870 101 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
positive regulation of adaptive immune response GO:0002821 61 0.012
regulation of secretion GO:0051046 274 0.012
cellular response to thyroid hormone stimulus GO:0097067 1 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
cellular protein catabolic process GO:0044257 155 0.011
organic acid biosynthetic process GO:0016053 86 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
multi multicellular organism process GO:0044706 109 0.011
leukocyte proliferation GO:0070661 172 0.011
regulation of protein kinase activity GO:0045859 232 0.011
regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling GO:0003027 1 0.011
brown fat cell differentiation GO:0050873 36 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
ossification GO:0001503 216 0.011
phagolysosome assembly GO:0001845 3 0.011
striated muscle cell development GO:0055002 125 0.011
membrane protein proteolysis GO:0033619 10 0.011
ear morphogenesis GO:0042471 118 0.011
cell activation involved in immune response GO:0002263 126 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
mitochondrion organization GO:0007005 134 0.011
myelination GO:0042552 74 0.011
steroid metabolic process GO:0008202 119 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
sterol transport GO:0015918 38 0.011
response to starvation GO:0042594 65 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
ceramide catabolic process GO:0046514 7 0.011
regulation of cellular response to stress GO:0080135 159 0.010
activation of immune response GO:0002253 138 0.010
regulation of cell adhesion GO:0030155 154 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
negative regulation of proteolysis GO:0045861 74 0.010
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.010
acylglycerol metabolic process GO:0006639 55 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
muscle tissue development GO:0060537 308 0.010
germ cell development GO:0007281 185 0.010
mapk cascade GO:0000165 281 0.010
positive regulation of transferase activity GO:0051347 167 0.010
methylation GO:0032259 134 0.010
transition metal ion homeostasis GO:0055076 54 0.010
axonogenesis GO:0007409 274 0.010
proteoglycan metabolic process GO:0006029 38 0.010
regulation of neuron projection development GO:0010975 169 0.010
phagosome maturation GO:0090382 4 0.010
negative regulation of growth GO:0045926 99 0.010
positive regulation of cytokine production GO:0001819 174 0.010
protein digestion GO:0044256 1 0.010
positive regulation of cell death GO:0010942 224 0.010
epidermis development GO:0008544 187 0.010
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.010
sensory perception GO:0007600 245 0.010

Gm2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.474
Human
inherited metabolic disorder DOID:655 0 0.474
Human
central nervous system disease DOID:331 0 0.136
Human
disease of anatomical entity DOID:7 0 0.136
Human
nervous system disease DOID:863 0 0.136
Human
retinal disease DOID:5679 0 0.054
sensory system disease DOID:0050155 0 0.054
eye and adnexa disease DOID:1492 0 0.054
eye disease DOID:5614 0 0.054
lipid storage disease DOID:9455 0 0.043
Human
lysosomal storage disease DOID:3211 0 0.043
Human
brain disease DOID:936 0 0.037
Human
sphingolipidosis DOID:1927 0 0.033
Human
immune system disease DOID:2914 0 0.030
cerebral degeneration DOID:1443 0 0.022
Human
neurodegenerative disease DOID:1289 0 0.017
retinal degeneration DOID:8466 0 0.013
disease of mental health DOID:150 0 0.011