Mus musculus

0 known processes

Timp1

tissue inhibitor of metalloproteinase 1

(Aliases: TIMP-1,MGC7143,Timp,Clgi)

Timp1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.810
positive regulation of defense response GO:0031349 124 0.621
cellular lipid metabolic process GO:0044255 323 0.575
cellular response to biotic stimulus GO:0071216 92 0.511
regulation of cell motility GO:2000145 236 0.509
Human
positive regulation of monocyte chemotaxis GO:0090026 2 0.507
oxidation reduction process GO:0055114 342 0.490
lipid biosynthetic process GO:0008610 179 0.449
cell adhesion GO:0007155 329 0.432
Fly
extrinsic apoptotic signaling pathway GO:0097191 126 0.404
regulation of calcium mediated signaling GO:0050848 19 0.396
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.364
chemotaxis GO:0006935 247 0.356
regulation of cell migration GO:0030334 219 0.346
Human
regulation of cytokine production GO:0001817 266 0.323
positive regulation of cell motility GO:2000147 116 0.307
regulation of mapk cascade GO:0043408 248 0.294
Mouse
regulation of ion transport GO:0043269 215 0.290
intracellular receptor signaling pathway GO:0030522 74 0.278
positive regulation of mapk cascade GO:0043410 170 0.272
regulation of eosinophil migration GO:2000416 2 0.270
extracellular matrix organization GO:0030198 147 0.264
Fly
cartilage development GO:0051216 140 0.261
Rat
thymocyte migration GO:0072679 2 0.256
cellular response to lipopolysaccharide GO:0071222 77 0.251
regulation of hydrolase activity GO:0051336 246 0.247
Human Mouse Fly
regulation of peptidase activity GO:0052547 96 0.243
Human Mouse Fly
inositol phosphate mediated signaling GO:0048016 13 0.237
cell chemotaxis GO:0060326 81 0.229
monocarboxylic acid metabolic process GO:0032787 191 0.228
rhythmic process GO:0048511 174 0.219
positive regulation of cell activation GO:0050867 158 0.214
skeletal system morphogenesis GO:0048705 203 0.211
regulation of leukocyte differentiation GO:1902105 159 0.210
steroid metabolic process GO:0008202 119 0.206
cell substrate adhesion GO:0031589 130 0.204
immune response activating signal transduction GO:0002757 116 0.203
response to endoplasmic reticulum stress GO:0034976 53 0.203
positive regulation of eosinophil migration GO:2000418 2 0.200
apoptotic signaling pathway GO:0097190 306 0.200
cation transport GO:0006812 399 0.199
regulation of protein serine threonine kinase activity GO:0071900 157 0.198
cytokine production GO:0001816 319 0.195
spermatogenesis GO:0007283 284 0.191
positive regulation of calcium mediated signaling GO:0050850 15 0.191
regulation of cell cycle GO:0051726 281 0.190
small gtpase mediated signal transduction GO:0007264 97 0.189
positive regulation of protein phosphorylation GO:0001934 242 0.183
regulation of inflammatory response GO:0050727 147 0.181
striated muscle tissue development GO:0014706 293 0.180
negative regulation of intracellular signal transduction GO:1902532 167 0.178
semaphorin plexin signaling pathway GO:0071526 21 0.178
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.177
positive regulation of innate immune response GO:0045089 80 0.175
ossification GO:0001503 216 0.174
bone development GO:0060348 120 0.169
organic hydroxy compound metabolic process GO:1901615 203 0.168
regulation of toll like receptor signaling pathway GO:0034121 20 0.166
anatomical structure homeostasis GO:0060249 145 0.164
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.162
activation of innate immune response GO:0002218 56 0.161
mapk cascade GO:0000165 281 0.158
Mouse
syncytium formation GO:0006949 43 0.157
skeletal system development GO:0001501 356 0.156
Rat
tumor necrosis factor production GO:0032640 50 0.150
carbohydrate biosynthetic process GO:0016051 74 0.150
activation of immune response GO:0002253 138 0.147
regulation of response to wounding GO:1903034 189 0.145
regulation of thymocyte migration GO:2000410 2 0.143
divalent metal ion transport GO:0070838 172 0.140
wound healing GO:0042060 157 0.140
Rat
protein maturation GO:0051604 176 0.137
Human Mouse Fly
regulation of endocytosis GO:0030100 69 0.137
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.137
cellular response to cytokine stimulus GO:0071345 189 0.135
positive regulation of programmed cell death GO:0043068 218 0.134
synaptic transmission GO:0007268 329 0.134
organonitrogen compound biosynthetic process GO:1901566 192 0.133
regulation of neuron death GO:1901214 134 0.132
positive regulation of thymocyte migration GO:2000412 2 0.132
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.132
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.130
response to molecule of bacterial origin GO:0002237 143 0.129
positive regulation of protein modification process GO:0031401 299 0.127
granulocyte migration GO:0097530 43 0.126
positive regulation of lymphocyte activation GO:0051251 140 0.126
homeostasis of number of cells GO:0048872 210 0.121
neuron death GO:0070997 154 0.120
myeloid leukocyte migration GO:0097529 57 0.119
b cell chemotaxis GO:0035754 3 0.118
regulation of secretion by cell GO:1903530 249 0.116
cell type specific apoptotic process GO:0097285 268 0.116
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.115
response to growth factor GO:0070848 198 0.114
cellular response to lipid GO:0071396 145 0.113
leukocyte migration GO:0050900 124 0.111
glycoprotein biosynthetic process GO:0009101 89 0.111
positive regulation of response to wounding GO:1903036 66 0.111
connective tissue development GO:0061448 179 0.110
Rat
leukocyte proliferation GO:0070661 172 0.110
leukocyte differentiation GO:0002521 342 0.109
regulation of endopeptidase activity GO:0052548 89 0.108
Human Mouse Fly
toll like receptor signaling pathway GO:0002224 38 0.108
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.107
response to interleukin 1 GO:0070555 11 0.106
eosinophil migration GO:0072677 3 0.105
regulation of cellular response to stress GO:0080135 159 0.104
activation of mapk activity GO:0000187 59 0.103
regulation of neuron projection development GO:0010975 169 0.102
steroid biosynthetic process GO:0006694 47 0.101
negative regulation of interferon gamma production GO:0032689 18 0.101
regulation of organelle organization GO:0033043 289 0.101
regulation of apoptotic signaling pathway GO:2001233 197 0.100
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.098
cellular response to molecule of bacterial origin GO:0071219 83 0.097
regulation of cell size GO:0008361 72 0.097
endocytosis GO:0006897 168 0.095
positive regulation of leukocyte differentiation GO:1902107 86 0.094
regulation of cell projection organization GO:0031344 206 0.092
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.091
regulation of map kinase activity GO:0043405 120 0.091
negative regulation of cytokine production GO:0001818 84 0.091
lipid catabolic process GO:0016042 69 0.091
developmental maturation GO:0021700 193 0.091
positive regulation of glucose transport GO:0010828 16 0.090
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.090
regulation of fibrinolysis GO:0051917 1 0.090
dendritic cell dendrite assembly GO:0097026 2 0.089
male gamete generation GO:0048232 285 0.089
pattern recognition receptor signaling pathway GO:0002221 47 0.088
regulation of transferase activity GO:0051338 263 0.088
positive regulation of lymphocyte differentiation GO:0045621 61 0.087
response to insulin GO:0032868 100 0.087
inflammatory response GO:0006954 244 0.086
inflammatory response to wounding GO:0090594 4 0.085
gland development GO:0048732 330 0.083
leukocyte chemotaxis GO:0030595 69 0.082
endochondral bone morphogenesis GO:0060350 50 0.082
positive regulation of kinase activity GO:0033674 155 0.082
reactive oxygen species metabolic process GO:0072593 84 0.081
regulation of chemotaxis GO:0050920 53 0.080
regulation of b cell chemotaxis GO:2000537 2 0.079
regulation of vesicle mediated transport GO:0060627 139 0.079
cellular amine metabolic process GO:0044106 44 0.078
lymphocyte differentiation GO:0030098 242 0.077
single organism cell adhesion GO:0098602 156 0.077
Fly
response to inorganic substance GO:0010035 96 0.077
negative regulation of hydrolase activity GO:0051346 71 0.076
Human Mouse Fly
response to corticosteroid GO:0031960 20 0.076
blood vessel morphogenesis GO:0048514 285 0.076
immune response regulating signaling pathway GO:0002764 125 0.076
cell recognition GO:0008037 83 0.075
response to hypoxia GO:0001666 58 0.075
telencephalon development GO:0021537 186 0.075
second messenger mediated signaling GO:0019932 73 0.074
positive regulation of t cell proliferation GO:0042102 52 0.073
regulation of defense response GO:0031347 233 0.072
cellular response to organonitrogen compound GO:0071417 145 0.071
leukocyte apoptotic process GO:0071887 71 0.071
negative regulation of peptidase activity GO:0010466 46 0.071
Human Mouse Fly
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.070
regulation of cell adhesion GO:0030155 154 0.070
Fly
cellular ketone metabolic process GO:0042180 84 0.069
natural killer cell chemotaxis GO:0035747 1 0.069
myeloid cell differentiation GO:0030099 233 0.069
positive regulation of protein kinase activity GO:0045860 144 0.069
epithelial cell proliferation GO:0050673 174 0.068
positive regulation of peptidase activity GO:0010952 49 0.068
negative regulation of protein processing GO:0010955 79 0.068
Human Mouse Fly
innate immune response GO:0045087 157 0.067
regulation of tumor necrosis factor production GO:0032680 49 0.067
regulation of protein localization GO:0032880 231 0.066
defense response to other organism GO:0098542 197 0.066
ras protein signal transduction GO:0007265 77 0.066
epithelial tube morphogenesis GO:0060562 303 0.066
response to oxygen levels GO:0070482 62 0.064
positive regulation of inflammatory response GO:0050729 47 0.064
positive regulation of cell migration GO:0030335 109 0.064
tissue homeostasis GO:0001894 115 0.064
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.064
forebrain development GO:0030900 302 0.064
negative regulation of molecular function GO:0044092 258 0.064
Human Mouse Fly
regulation of cellular amine metabolic process GO:0033238 20 0.063
positive regulation of map kinase activity GO:0043406 84 0.063
positive regulation of cell death GO:0010942 224 0.063
fatty acid metabolic process GO:0006631 121 0.062
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.062
dendritic cell differentiation GO:0097028 26 0.062
alcohol metabolic process GO:0006066 116 0.061
regulation of lipid biosynthetic process GO:0046890 54 0.061
negative regulation of protein maturation GO:1903318 79 0.061
Human Mouse Fly
regulation of natural killer cell chemotaxis GO:2000501 1 0.061
organic acid biosynthetic process GO:0016053 86 0.061
regulation of cell activation GO:0050865 289 0.061
lymphocyte proliferation GO:0046651 164 0.061
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
Mouse
regulation of secretion GO:0051046 274 0.060
nucleoside phosphate metabolic process GO:0006753 338 0.060
Mouse
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.059
astrocyte cell migration GO:0043615 3 0.059
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.059
regulation of lymphocyte differentiation GO:0045619 107 0.059
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.058
myotube differentiation GO:0014902 105 0.057
regulation of monocyte chemotaxis GO:0090025 3 0.057
regulation of protein kinase activity GO:0045859 232 0.057
positive regulation of transferase activity GO:0051347 167 0.057
regulation of protein transport GO:0051223 163 0.057
rho protein signal transduction GO:0007266 32 0.057
regulation of cellular ketone metabolic process GO:0010565 66 0.057
cellular response to inorganic substance GO:0071241 37 0.057
regulation of interferon gamma production GO:0032649 57 0.057
regulation of innate immune response GO:0045088 91 0.056
skeletal muscle organ development GO:0060538 163 0.056
carbohydrate derivative biosynthetic process GO:1901137 183 0.056
negative regulation of fibrinolysis GO:0051918 1 0.056
regulation of leukocyte apoptotic process GO:2000106 56 0.056
positive regulation of t cell activation GO:0050870 101 0.056
positive regulation of b cell chemotaxis GO:2000538 2 0.055
calcium ion transport GO:0006816 159 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
positive regulation of secretion by cell GO:1903532 114 0.054
organ maturation GO:0048799 17 0.054
response to oxidative stress GO:0006979 123 0.054
respiratory tube development GO:0030323 167 0.053
divalent inorganic cation transport GO:0072511 178 0.053
positive regulation of cytokine production GO:0001819 174 0.053
regulation of protein processing GO:0070613 96 0.052
Human Mouse Fly
response to extracellular stimulus GO:0009991 127 0.052
bone mineralization GO:0030282 54 0.052
cellular response to gonadotropin stimulus GO:0071371 4 0.052
endomembrane system organization GO:0010256 147 0.051
single organismal cell cell adhesion GO:0016337 131 0.051
Fly
peripheral nervous system axon regeneration GO:0014012 2 0.051
negative regulation of immune system process GO:0002683 209 0.051
multicellular organismal homeostasis GO:0048871 164 0.050
signal transduction in absence of ligand GO:0038034 55 0.050
cell matrix adhesion GO:0007160 68 0.050
regulation of hormone levels GO:0010817 211 0.050
lymphocyte mediated immunity GO:0002449 139 0.050
striated muscle cell development GO:0055002 125 0.050
morphogenesis of a branching epithelium GO:0061138 193 0.050
antibacterial peptide secretion GO:0002779 1 0.049
glucose transport GO:0015758 56 0.049
myoblast proliferation GO:0051450 11 0.049
regulation of protein secretion GO:0050708 82 0.048
monosaccharide transport GO:0015749 58 0.048
cellular response to oxidative stress GO:0034599 76 0.048
regulation of dendritic cell apoptotic process GO:2000668 3 0.048
regulation of t cell activation GO:0050863 170 0.048
positive regulation of lipid biosynthetic process GO:0046889 18 0.047
regulation of natural killer cell activation GO:0032814 22 0.047
myotube cell development GO:0014904 60 0.047
t cell extravasation GO:0072683 4 0.047
regulation of muscle hypertrophy GO:0014743 13 0.047
isoprenoid metabolic process GO:0006720 29 0.047
circadian rhythm GO:0007623 114 0.047
myeloid cell homeostasis GO:0002262 114 0.047
regulation of homeostatic process GO:0032844 182 0.046
negative regulation of cell growth GO:0030308 44 0.046
response to organonitrogen compound GO:0010243 246 0.046
Rat
response to organic cyclic compound GO:0014070 198 0.046
cellular response to interferon alpha GO:0035457 4 0.046
development of primary sexual characteristics GO:0045137 143 0.045
regulation of kinase activity GO:0043549 249 0.045
antibacterial peptide biosynthetic process GO:0002780 2 0.045
peptidyl amino acid modification GO:0018193 336 0.045
platelet aggregation GO:0070527 20 0.045
regulation of ossification GO:0030278 112 0.045
glycosyl compound metabolic process GO:1901657 246 0.044
regulation of cell cycle process GO:0010564 160 0.044
negative regulation of endopeptidase activity GO:0010951 44 0.044
Human Mouse Fly
negative regulation of neuron death GO:1901215 98 0.043
response to lipopolysaccharide GO:0032496 128 0.043
immune effector process GO:0002252 321 0.043
establishment or maintenance of cell polarity GO:0007163 86 0.043
regulation of androgen receptor signaling pathway GO:0060765 3 0.043
leukocyte mediated cytotoxicity GO:0001909 62 0.043
t helper 2 cell cytokine production GO:0035745 4 0.042
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.042
muscle tissue development GO:0060537 308 0.042
regulation of erk1 and erk2 cascade GO:0070372 71 0.042
positive regulation of calcineurin nfat signaling cascade GO:0070886 2 0.042
primary alcohol catabolic process GO:0034310 2 0.042
cellular response to growth factor stimulus GO:0071363 197 0.042
cell growth GO:0016049 130 0.042
innate immune response activating signal transduction GO:0002758 50 0.042
fibrinolysis GO:0042730 3 0.041
sensory perception GO:0007600 245 0.041
cellular response to hormone stimulus GO:0032870 150 0.041
positive regulation of intracellular transport GO:0032388 70 0.041
negative regulation of cellular component organization GO:0051129 194 0.041
bone morphogenesis GO:0060349 78 0.041
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.041
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.041
positive regulation of proteolysis GO:0045862 85 0.040
unsaturated fatty acid metabolic process GO:0033559 31 0.040
intrinsic apoptotic signaling pathway GO:0097193 132 0.040
energy derivation by oxidation of organic compounds GO:0015980 77 0.040
response to transforming growth factor beta GO:0071559 88 0.040
response to peptide hormone GO:0043434 127 0.040
Rat
cdc42 protein signal transduction GO:0032488 0 0.040
positive regulation of secretion GO:0051047 130 0.039
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.039
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.039
response to metal ion GO:0010038 47 0.039
myoblast differentiation GO:0045445 52 0.039
regulation of steroid hormone biosynthetic process GO:0090030 4 0.039
protein processing GO:0016485 163 0.039
Human Mouse Fly
regulation of lymphocyte activation GO:0051249 240 0.038
cytokine mediated signaling pathway GO:0019221 115 0.038
acetylcholine transport GO:0015870 2 0.038
phagocytosis GO:0006909 66 0.038
regulation of cytokine secretion GO:0050707 61 0.038
response to decreased oxygen levels GO:0036293 59 0.038
terpenoid metabolic process GO:0006721 25 0.038
ovulation cycle GO:0042698 59 0.038
regulation of plasminogen activation GO:0010755 4 0.038
angiogenesis GO:0001525 201 0.037
regulation of membrane potential GO:0042391 192 0.037
response to fibroblast growth factor GO:0071774 47 0.037
chondrocyte differentiation GO:0002062 72 0.037
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.036
protein localization to organelle GO:0033365 185 0.036
translation GO:0006412 93 0.036
signal transduction by p53 class mediator GO:0072331 51 0.036
regulation of t cell proliferation GO:0042129 92 0.036
wnt signaling pathway GO:0016055 188 0.036
muscle cell differentiation GO:0042692 261 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.036
Mouse
negative regulation of growth GO:0045926 99 0.036
regulation of ras protein signal transduction GO:0046578 114 0.036
cellular amino acid metabolic process GO:0006520 103 0.035
neutrophil migration GO:1990266 37 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
glial cell differentiation GO:0010001 131 0.035
production of molecular mediator of immune response GO:0002440 103 0.035
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 11 0.035
negative regulation of apoptotic signaling pathway GO:2001234 104 0.035
lung development GO:0030324 164 0.034
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.034
negative regulation of chemotaxis GO:0050922 11 0.034
cellularization GO:0007349 1 0.034
neutrophil chemotaxis GO:0030593 36 0.034
antimicrobial peptide production GO:0002775 2 0.034
sensory organ morphogenesis GO:0090596 242 0.034
fibroblast proliferation GO:0048144 35 0.034
chromatin modification GO:0016568 187 0.034
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.033
dna metabolic process GO:0006259 303 0.033
cell maturation GO:0048469 127 0.033
t cell proliferation GO:0042098 120 0.033
anatomical structure maturation GO:0071695 49 0.033
acetate ester transport GO:1901374 2 0.033
positive regulation of nervous system development GO:0051962 221 0.033
development of primary female sexual characteristics GO:0046545 73 0.032
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.032
erk1 and erk2 cascade GO:0070371 77 0.032
regulation of fibroblast proliferation GO:0048145 34 0.032
regulation of protein maturation GO:1903317 96 0.032
Human Mouse Fly
mesenchymal epithelial cell signaling GO:0060638 9 0.032
negative regulation of tumor necrosis factor production GO:0032720 17 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
Human Mouse Fly
cytoplasmic transport GO:0016482 234 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
Human Mouse Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.031
positive regulation of lymphocyte proliferation GO:0050671 70 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
Mouse
positive regulation of protein transport GO:0051222 93 0.031
negative regulation of nervous system development GO:0051961 156 0.031
cellular calcium ion homeostasis GO:0006874 119 0.031
mesenchyme development GO:0060485 152 0.031
carbohydrate transport GO:0008643 62 0.031
axonogenesis GO:0007409 274 0.031
chromatin organization GO:0006325 206 0.031
regulation of cysteine type endopeptidase activity GO:2000116 65 0.031
regulation of steroid metabolic process GO:0019218 39 0.031
negative regulation of macrophage apoptotic process GO:2000110 3 0.031
cell adhesion mediated by integrin GO:0033627 18 0.030
gonad development GO:0008406 141 0.030
polysaccharide metabolic process GO:0005976 39 0.030
apoptotic mitochondrial changes GO:0008637 48 0.030
natural killer cell activation GO:0030101 44 0.029
positive regulation of smooth muscle cell migration GO:0014911 4 0.029
response to acid chemical GO:0001101 111 0.029
regulation of glucose transport GO:0010827 32 0.029
regulation of body fluid levels GO:0050878 162 0.029
calcineurin nfat signaling cascade GO:0033173 8 0.029
organelle fission GO:0048285 170 0.029
dendritic cell apoptotic process GO:0097048 3 0.029
regulation of t helper 1 cell cytokine production GO:2000554 1 0.029
leukocyte mediated immunity GO:0002443 174 0.029
regulation of cellular component biogenesis GO:0044087 181 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.028
negative regulation of macrophage chemotaxis GO:0010760 1 0.028
regulation of system process GO:0044057 200 0.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.028
muscle cell development GO:0055001 133 0.028
positive regulation of stress activated mapk cascade GO:0032874 48 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
stress activated protein kinase signaling cascade GO:0031098 81 0.028
regulation of cartilage development GO:0061035 44 0.028
antimicrobial peptide biosynthetic process GO:0002777 2 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.027
transmembrane transport GO:0055085 412 0.027
nucleotide metabolic process GO:0009117 332 0.027
Mouse
glycoprotein metabolic process GO:0009100 116 0.027
cellular response to acid chemical GO:0071229 68 0.027
organic anion transport GO:0015711 137 0.027
wound healing involved in inflammatory response GO:0002246 4 0.027
stem cell differentiation GO:0048863 268 0.027
mesenchymal cell differentiation GO:0048762 107 0.027
regulation of mitochondrion organization GO:0010821 27 0.027
organelle localization GO:0051640 179 0.027
tissue remodeling GO:0048771 102 0.027
positive regulation of type 2 immune response GO:0002830 9 0.026
antimicrobial peptide secretion GO:0002776 1 0.026
regulation of tissue remodeling GO:0034103 38 0.026
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.026
maintenance of cell number GO:0098727 3 0.026
regulation of cell growth GO:0001558 91 0.026
forebrain cell migration GO:0021885 58 0.026
primary alcohol metabolic process GO:0034308 11 0.026
elastic fiber assembly GO:0048251 4 0.026
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.026
protein secretion GO:0009306 111 0.026
regulation of neuron apoptotic process GO:0043523 122 0.026
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.026
carbohydrate metabolic process GO:0005975 230 0.026
purine containing compound metabolic process GO:0072521 311 0.026
Mouse
regulation of proteolysis GO:0030162 164 0.026
Human Mouse Fly
regulation of striated muscle cell differentiation GO:0051153 81 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
positive regulation of bone remodeling GO:0046852 13 0.025
isoprenoid catabolic process GO:0008300 2 0.025
regulation of jnk cascade GO:0046328 62 0.025
female sex differentiation GO:0046660 84 0.025
female gamete generation GO:0007292 74 0.025
head morphogenesis GO:0060323 34 0.025
mature dendritic cell differentiation GO:0097029 3 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
maintenance of location GO:0051235 89 0.025
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
i kappab kinase nf kappab signaling GO:0007249 85 0.025
intracellular protein transport GO:0006886 204 0.025
ear development GO:0043583 200 0.025
extracellular structure organization GO:0043062 148 0.025
Fly
positive regulation of organelle organization GO:0010638 128 0.025
regulation of neuron differentiation GO:0045664 281 0.025
Mouse
defense response to bacterium GO:0042742 119 0.025
early endosome to late endosome transport GO:0045022 2 0.025
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.025
cellular response to abiotic stimulus GO:0071214 56 0.024
epithelial cell development GO:0002064 159 0.024
regulation of cellular response to oxidative stress GO:1900407 19 0.024
negative regulation of cell migration GO:0030336 59 0.024
Human
hexose metabolic process GO:0019318 98 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
developmental growth involved in morphogenesis GO:0060560 138 0.024
Fly
muscle cell migration GO:0014812 19 0.024
respiratory system development GO:0060541 190 0.024
Fly
regulation of killing of cells of other organism GO:0051709 4 0.024
positive regulation of t cell differentiation GO:0045582 52 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
positive regulation of endocytosis GO:0045807 42 0.024
syncytium formation by plasma membrane fusion GO:0000768 42 0.024
androgen receptor signaling pathway GO:0030521 8 0.024
intussusceptive angiogenesis GO:0002041 2 0.024
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 8 0.023
negative regulation of neuron projection development GO:0010977 50 0.023
fatty acid derivative metabolic process GO:1901568 33 0.023
b cell activation GO:0042113 161 0.023
canonical wnt signaling pathway GO:0060070 130 0.023
positive regulation of neuron differentiation GO:0045666 141 0.023
lung alveolus development GO:0048286 45 0.023
regulation of stress activated mapk cascade GO:0032872 69 0.023
cellular homeostasis GO:0019725 240 0.023
morphogenesis of a branching structure GO:0001763 203 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
ovulation GO:0030728 15 0.023
interferon gamma production GO:0032609 67 0.023
positive regulation of cellular component biogenesis GO:0044089 94 0.023
positive regulation of nuclear division GO:0051785 27 0.023
long term synaptic potentiation GO:0060291 25 0.023
negative regulation of cell adhesion mediated by integrin GO:0033629 2 0.022
organic hydroxy compound biosynthetic process GO:1901617 77 0.022

Timp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
connective tissue disease DOID:65 0 0.031
glaucoma DOID:1686 0 0.027
retinal disease DOID:5679 0 0.027
retinal degeneration DOID:8466 0 0.027
sensory system disease DOID:0050155 0 0.027
eye and adnexa disease DOID:1492 0 0.027
nervous system disease DOID:863 0 0.027
eye disease DOID:5614 0 0.027