Mus musculus

0 known processes

Slfn5

schlafen 5

(Aliases: AI956840)

Slfn5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 321 0.106
nucleobase containing small molecule metabolic process GO:0055086 352 0.098
glycosyl compound metabolic process GO:1901657 246 0.087
nucleoside phosphate metabolic process GO:0006753 338 0.076
heterocycle catabolic process GO:0046700 280 0.075
purine nucleoside metabolic process GO:0042278 241 0.075
regulation of cytokine production GO:0001817 266 0.073
nucleotide metabolic process GO:0009117 332 0.071
carbohydrate derivative catabolic process GO:1901136 231 0.071
ribonucleoside catabolic process GO:0042454 206 0.060
organophosphate catabolic process GO:0046434 232 0.058
purine nucleotide metabolic process GO:0006163 302 0.056
ribose phosphate metabolic process GO:0019693 291 0.056
cellular amine metabolic process GO:0044106 44 0.056
purine containing compound metabolic process GO:0072521 311 0.056
cytokine production GO:0001816 319 0.055
purine nucleotide catabolic process GO:0006195 211 0.054
nucleoside phosphate catabolic process GO:1901292 222 0.054
myeloid cell differentiation GO:0030099 233 0.053
purine ribonucleoside metabolic process GO:0046128 241 0.050
small gtpase mediated signal transduction GO:0007264 97 0.050
ras protein signal transduction GO:0007265 77 0.048
purine ribonucleoside catabolic process GO:0046130 205 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.048
mapk cascade GO:0000165 281 0.047
cellular ketone metabolic process GO:0042180 84 0.046
defense response to other organism GO:0098542 197 0.046
purine containing compound catabolic process GO:0072523 213 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.045
aromatic compound catabolic process GO:0019439 286 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.045
ribonucleotide metabolic process GO:0009259 291 0.044
regulation of purine nucleotide metabolic process GO:1900542 169 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.042
t cell activation GO:0042110 289 0.041
guanosine containing compound catabolic process GO:1901069 144 0.041
cellular amino acid metabolic process GO:0006520 103 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
myeloid leukocyte differentiation GO:0002573 119 0.039
organic cyclic compound catabolic process GO:1901361 295 0.039
amine metabolic process GO:0009308 45 0.039
nucleoside triphosphate metabolic process GO:0009141 230 0.038
nucleoside catabolic process GO:0009164 206 0.037
anion transport GO:0006820 177 0.037
nucleoside metabolic process GO:0009116 246 0.036
interspecies interaction between organisms GO:0044419 83 0.036
positive regulation of nucleotide metabolic process GO:0045981 114 0.036
regulation of mapk cascade GO:0043408 248 0.036
organonitrogen compound catabolic process GO:1901565 264 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
positive regulation of hydrolase activity GO:0051345 148 0.035
regulation of defense response GO:0031347 233 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.035
regulation of innate immune response GO:0045088 91 0.035
glycosyl compound catabolic process GO:1901658 206 0.034
lymphocyte mediated immunity GO:0002449 139 0.034
immune response regulating signaling pathway GO:0002764 125 0.033
innate immune response GO:0045087 157 0.032
positive regulation of cell death GO:0010942 224 0.032
inflammatory response GO:0006954 244 0.032
regulation of nucleotide metabolic process GO:0006140 169 0.032
defense response to virus GO:0051607 68 0.032
gtp catabolic process GO:0006184 143 0.031
guanosine containing compound metabolic process GO:1901068 144 0.031
rho protein signal transduction GO:0007266 32 0.031
regulation of cell activation GO:0050865 289 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
multicellular organismal homeostasis GO:0048871 164 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
leukocyte differentiation GO:0002521 342 0.030
cation transmembrane transport GO:0098655 266 0.030
leukocyte mediated immunity GO:0002443 174 0.030
male gamete generation GO:0048232 285 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
ossification GO:0001503 216 0.029
synaptic transmission GO:0007268 329 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
nucleoside triphosphate catabolic process GO:0009143 205 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
multicellular organismal signaling GO:0035637 91 0.029
positive regulation of defense response GO:0031349 124 0.028
positive regulation of gtpase activity GO:0043547 85 0.028
regulation of membrane potential GO:0042391 192 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
carbohydrate metabolic process GO:0005975 230 0.028
nucleotide catabolic process GO:0009166 217 0.028
regulation of protein localization GO:0032880 231 0.028
cellular response to lipopolysaccharide GO:0071222 77 0.028
neuronal action potential GO:0019228 54 0.028
regulation of ion transport GO:0043269 215 0.028
positive regulation of cytokine production GO:0001819 174 0.028
regulation of cellular component biogenesis GO:0044087 181 0.027
positive regulation of immune effector process GO:0002699 107 0.027
peptidyl amino acid modification GO:0018193 336 0.027
regulation of nucleoside metabolic process GO:0009118 130 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
apoptotic signaling pathway GO:0097190 306 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
viral process GO:0016032 41 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
cell activation involved in immune response GO:0002263 126 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
gtp metabolic process GO:0046039 144 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
g protein coupled receptor signaling pathway GO:0007186 243 0.025
positive regulation of protein modification process GO:0031401 299 0.025
regulation of cell cycle GO:0051726 281 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
cell type specific apoptotic process GO:0097285 268 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
negative regulation of cell development GO:0010721 169 0.025
organophosphate biosynthetic process GO:0090407 122 0.025
action potential GO:0001508 78 0.025
transmission of nerve impulse GO:0019226 76 0.024
regulation of hydrolase activity GO:0051336 246 0.024
negative regulation of immune system process GO:0002683 209 0.024
muscle tissue development GO:0060537 308 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
negative regulation of molecular function GO:0044092 258 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.024
regulation of neuron differentiation GO:0045664 281 0.024
regulation of multi organism process GO:0043900 111 0.023
cation transport GO:0006812 399 0.023
transmembrane transport GO:0055085 412 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
stem cell development GO:0048864 219 0.023
skeletal system development GO:0001501 356 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
positive regulation of nervous system development GO:0051962 221 0.022
macromolecule catabolic process GO:0009057 281 0.022
response to lipopolysaccharide GO:0032496 128 0.022
exocytosis GO:0006887 121 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
regulation of kinase activity GO:0043549 249 0.021
circulatory system process GO:0003013 197 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
lymphocyte differentiation GO:0030098 242 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
regulation of gtp catabolic process GO:0033124 113 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
positive regulation of ras gtpase activity GO:0032320 65 0.020
dna metabolic process GO:0006259 303 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
cellular response to lipid GO:0071396 145 0.020
regulation of organelle organization GO:0033043 289 0.020
protein ubiquitination GO:0016567 171 0.020
regulation of t cell activation GO:0050863 170 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.019
negative regulation of immune effector process GO:0002698 55 0.019
positive regulation of gtp catabolic process GO:0033126 85 0.019
membrane organization GO:0061024 245 0.019
stem cell differentiation GO:0048863 268 0.019
leukocyte proliferation GO:0070661 172 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of anatomical structure size GO:0090066 178 0.019
cytoplasmic transport GO:0016482 234 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
innate immune response activating signal transduction GO:0002758 50 0.018
negative regulation of multi organism process GO:0043901 68 0.018
fat cell differentiation GO:0045444 160 0.018
blood vessel morphogenesis GO:0048514 285 0.018
spermatogenesis GO:0007283 284 0.018
regulation of secretion by cell GO:1903530 249 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
chromatin organization GO:0006325 206 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
regulation of inflammatory response GO:0050727 147 0.018
regulation of secretion GO:0051046 274 0.018
gland development GO:0048732 330 0.018
myeloid leukocyte activation GO:0002274 83 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
gliogenesis GO:0042063 141 0.018
stem cell maintenance GO:0019827 130 0.017
protein processing GO:0016485 163 0.017
regulation of protein transport GO:0051223 163 0.017
viral transcription GO:0019083 3 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
glucose homeostasis GO:0042593 128 0.017
activation of immune response GO:0002253 138 0.017
extracellular matrix organization GO:0030198 147 0.017
protein maturation GO:0051604 176 0.017
divalent inorganic cation transport GO:0072511 178 0.017
regulation of transferase activity GO:0051338 263 0.017
regulation of cell migration GO:0030334 219 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
forebrain development GO:0030900 302 0.017
positive regulation of cell development GO:0010720 237 0.017
negative regulation of viral genome replication GO:0045071 10 0.017
positive regulation of transferase activity GO:0051347 167 0.017
chromatin modification GO:0016568 187 0.017
cardiac muscle tissue development GO:0048738 130 0.017
pattern recognition receptor signaling pathway GO:0002221 47 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
cytokine mediated signaling pathway GO:0019221 115 0.016
ion transmembrane transport GO:0034220 361 0.016
carbohydrate homeostasis GO:0033500 128 0.016
anatomical structure homeostasis GO:0060249 145 0.016
protein localization to organelle GO:0033365 185 0.016
regulation of system process GO:0044057 200 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
sodium ion transport GO:0006814 73 0.016
protein catabolic process GO:0030163 221 0.016
oxidation reduction process GO:0055114 342 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
regulation of ras gtpase activity GO:0032318 88 0.016
regulation of adaptive immune response GO:0002819 90 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.016
positive regulation of innate immune response GO:0045089 80 0.016
muscle cell development GO:0055001 133 0.016
maintenance of location GO:0051235 89 0.016
regulation of rho protein signal transduction GO:0035023 71 0.016
negative regulation of nervous system development GO:0051961 156 0.016
regulation of leukocyte proliferation GO:0070663 121 0.015
cell adhesion GO:0007155 329 0.015
telencephalon development GO:0021537 186 0.015
epithelial cell proliferation GO:0050673 174 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
blood circulation GO:0008015 195 0.015
sequestering of metal ion GO:0051238 19 0.015
positive regulation of cell activation GO:0050867 158 0.015
angiogenesis GO:0001525 201 0.015
cellular lipid metabolic process GO:0044255 323 0.015
epidermis development GO:0008544 187 0.015
cellular homeostasis GO:0019725 240 0.015
regulation of hormone levels GO:0010817 211 0.015
lung development GO:0030324 164 0.015
negative regulation of defense response GO:0031348 77 0.015
muscle cell differentiation GO:0042692 261 0.015
multicellular organism growth GO:0035264 161 0.014
endocytosis GO:0006897 168 0.014
positive regulation of viral genome replication GO:0045070 2 0.014
cell division GO:0051301 120 0.014
extracellular structure organization GO:0043062 148 0.014
cell growth GO:0016049 130 0.014
skeletal muscle organ development GO:0060538 163 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.014
response to organic cyclic compound GO:0014070 198 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
striated muscle tissue development GO:0014706 293 0.014
glial cell differentiation GO:0010001 131 0.014
positive regulation of kinase activity GO:0033674 155 0.014
regulation of viral transcription GO:0046782 3 0.014
cation homeostasis GO:0055080 212 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
negative regulation of growth GO:0045926 99 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
intracellular protein transport GO:0006886 204 0.014
calcium ion transport GO:0006816 159 0.014
ear development GO:0043583 200 0.014
positive regulation of secretion by cell GO:1903532 114 0.013
adaptive immune response GO:0002250 155 0.013
camera type eye development GO:0043010 266 0.013
rna processing GO:0006396 105 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
mrna metabolic process GO:0016071 84 0.013
regulation of homeostatic process GO:0032844 182 0.013
organelle assembly GO:0070925 177 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
germ cell development GO:0007281 185 0.013
kidney development GO:0001822 213 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of response to wounding GO:1903034 189 0.013
immune response activating signal transduction GO:0002757 116 0.013
cellular protein complex assembly GO:0043623 116 0.013
sequestering of calcium ion GO:0051208 18 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
renal system development GO:0072001 225 0.013
viral gene expression GO:0019080 3 0.013
spermatid development GO:0007286 108 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
regulation of rho gtpase activity GO:0032319 58 0.013
skin development GO:0043588 220 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
respiratory tube development GO:0030323 167 0.012
regulation of binding GO:0051098 111 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
alpha beta t cell activation GO:0046631 91 0.012
negative regulation of protein modification process GO:0031400 163 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
response to extracellular stimulus GO:0009991 127 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
positive regulation of growth GO:0045927 104 0.012
glycoprotein metabolic process GO:0009100 116 0.012
small molecule biosynthetic process GO:0044283 132 0.012
tissue remodeling GO:0048771 102 0.012
regulation of protein kinase activity GO:0045859 232 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.012
organic acid transport GO:0015849 101 0.012
sensory organ morphogenesis GO:0090596 242 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
respiratory system development GO:0060541 190 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of body fluid levels GO:0050878 162 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
atp metabolic process GO:0046034 75 0.012
tissue homeostasis GO:0001894 115 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
calcium ion homeostasis GO:0055074 127 0.011
response to acid chemical GO:0001101 111 0.011
regulation of ossification GO:0030278 112 0.011
translation GO:0006412 93 0.011
regulation of translation GO:0006417 71 0.011
viral genome replication GO:0019079 17 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
regulation of protein processing GO:0070613 96 0.011
muscle system process GO:0003012 141 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
nuclear transport GO:0051169 139 0.011
negative regulation of kinase activity GO:0033673 81 0.011
activation of innate immune response GO:0002218 56 0.011
regulation of cell cycle process GO:0010564 160 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.011
organic anion transport GO:0015711 137 0.011
atp catabolic process GO:0006200 55 0.011
myeloid cell homeostasis GO:0002262 114 0.011
monosaccharide transport GO:0015749 58 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
lymphocyte proliferation GO:0046651 164 0.011
glucose transport GO:0015758 56 0.011
regulation of cell motility GO:2000145 236 0.011
interleukin 8 production GO:0032637 4 0.011
regulation of protein complex assembly GO:0043254 83 0.011
cell recognition GO:0008037 83 0.011
regulation of cell adhesion GO:0030155 154 0.011
lipid biosynthetic process GO:0008610 179 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
positive regulation of adaptive immune response GO:0002821 61 0.011
chemotaxis GO:0006935 247 0.010
glycosylation GO:0070085 62 0.010
neuromuscular process GO:0050905 99 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
inorganic anion transport GO:0015698 43 0.010
neuron migration GO:0001764 122 0.010
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.010
sensory perception GO:0007600 245 0.010
negative regulation of viral transcription GO:0032897 3 0.010
developmental maturation GO:0021700 193 0.010
hexose transport GO:0008645 56 0.010
connective tissue development GO:0061448 179 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
striated muscle cell development GO:0055002 125 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.010
negative regulation of protein maturation GO:1903318 79 0.010
protein secretion GO:0009306 111 0.010
urogenital system development GO:0001655 261 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010

Slfn5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.014
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012