Mus musculus

17 known processes

Txnrd2

thioredoxin reductase 2

(Aliases: TGR,AA118373,ESTM573010,Trxrd2,Tr3,Trxr2)

Txnrd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.094
Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.049
organonitrogen compound biosynthetic process GO:1901566 192 0.047
monocarboxylic acid metabolic process GO:0032787 191 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
carbohydrate derivative biosynthetic process GO:1901137 183 0.039
nitrogen compound transport GO:0071705 271 0.039
cellular ketone metabolic process GO:0042180 84 0.038
cellular amino acid metabolic process GO:0006520 103 0.037
cofactor metabolic process GO:0051186 80 0.033
mitochondrion organization GO:0007005 134 0.033
carbohydrate metabolic process GO:0005975 230 0.033
homeostasis of number of cells GO:0048872 210 0.031
transmembrane transport GO:0055085 412 0.031
response to oxidative stress GO:0006979 123 0.030
peptide transport GO:0015833 133 0.029
sulfur compound metabolic process GO:0006790 100 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
carboxylic acid biosynthetic process GO:0046394 86 0.027
cofactor biosynthetic process GO:0051188 41 0.027
amine metabolic process GO:0009308 45 0.026
spermatogenesis GO:0007283 284 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
cellular amine metabolic process GO:0044106 44 0.025
amide transport GO:0042886 138 0.023
male gamete generation GO:0048232 285 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
action potential GO:0001508 78 0.022
cellular lipid metabolic process GO:0044255 323 0.022
purine containing compound metabolic process GO:0072521 311 0.022
organonitrogen compound catabolic process GO:1901565 264 0.021
regulation of hormone levels GO:0010817 211 0.021
compound eye development GO:0048749 1 0.020
sensory perception GO:0007600 245 0.020
cellular homeostasis GO:0019725 240 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
nucleotide metabolic process GO:0009117 332 0.020
ribonucleotide metabolic process GO:0009259 291 0.019
porphyrin containing compound metabolic process GO:0006778 22 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
regulation of mapk cascade GO:0043408 248 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
peptidyl amino acid modification GO:0018193 336 0.019
lateral inhibition GO:0046331 1 0.019
cytoplasmic transport GO:0016482 234 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
cytokine production GO:0001816 319 0.018
t cell activation GO:0042110 289 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
small molecule catabolic process GO:0044282 71 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
organic acid biosynthetic process GO:0016053 86 0.017
positive regulation of protein modification process GO:0031401 299 0.017
porphyrin containing compound biosynthetic process GO:0006779 16 0.017
cation homeostasis GO:0055080 212 0.017
response to organic cyclic compound GO:0014070 198 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
anion transport GO:0006820 177 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
heterocycle catabolic process GO:0046700 280 0.017
regulation of cytokine production GO:0001817 266 0.016
ras protein signal transduction GO:0007265 77 0.016
response to organonitrogen compound GO:0010243 246 0.016
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.016
inflammatory response GO:0006954 244 0.016
gland development GO:0048732 330 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of secretion by cell GO:1903530 249 0.016
myeloid cell differentiation GO:0030099 233 0.016
cation transport GO:0006812 399 0.016
regulation of organelle organization GO:0033043 289 0.016
regulation of membrane potential GO:0042391 192 0.015
regulation of feeding behavior GO:0060259 3 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
negative regulation of molecular function GO:0044092 258 0.015
response to inorganic substance GO:0010035 96 0.015
Rat
cellular response to oxidative stress GO:0034599 76 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
multicellular organismal signaling GO:0035637 91 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
apoptotic signaling pathway GO:0097190 306 0.015
glucose homeostasis GO:0042593 128 0.015
leukocyte differentiation GO:0002521 342 0.015
intracellular protein transport GO:0006886 204 0.015
dicarboxylic acid catabolic process GO:0043649 2 0.015
carbohydrate homeostasis GO:0033500 128 0.014
cell type specific apoptotic process GO:0097285 268 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
lipid biosynthetic process GO:0008610 179 0.014
nucleoside bisphosphate metabolic process GO:0033865 9 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
muscle cell differentiation GO:0042692 261 0.014
aromatic compound catabolic process GO:0019439 286 0.014
myeloid cell homeostasis GO:0002262 114 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
regulation of cell activation GO:0050865 289 0.014
ion transmembrane transport GO:0034220 361 0.014
glycosylation GO:0070085 62 0.014
rho protein signal transduction GO:0007266 32 0.014
protein glycosylation GO:0006486 55 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
regulation of transferase activity GO:0051338 263 0.014
neuronal action potential GO:0019228 54 0.014
nucleoside metabolic process GO:0009116 246 0.014
tetrapyrrole biosynthetic process GO:0033014 16 0.014
heme biosynthetic process GO:0006783 12 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of protein localization GO:0032880 231 0.014
alcohol metabolic process GO:0006066 116 0.014
cellular ion homeostasis GO:0006873 165 0.014
response to monosaccharide GO:0034284 67 0.013
multi multicellular organism process GO:0044706 109 0.013
mapk cascade GO:0000165 281 0.013
coenzyme metabolic process GO:0006732 52 0.013
cellular chemical homeostasis GO:0055082 215 0.013
small molecule biosynthetic process GO:0044283 132 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
skin development GO:0043588 220 0.013
peptide secretion GO:0002790 114 0.013
c4 dicarboxylate transport GO:0015740 3 0.013
histone modification GO:0016570 159 0.013
regulation of defense response GO:0031347 233 0.013
skeletal system development GO:0001501 356 0.012
organic acid catabolic process GO:0016054 51 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
wnt signaling pathway GO:0016055 188 0.012
oligopeptide transmembrane transport GO:0035672 4 0.012
immune effector process GO:0002252 321 0.012
glycoprotein metabolic process GO:0009100 116 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
epithelial cell development GO:0002064 159 0.012
coenzyme a metabolic process GO:0015936 8 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
regulation of homeostatic process GO:0032844 182 0.011
pigment biosynthetic process GO:0046148 26 0.011
iron ion homeostasis GO:0055072 36 0.011
maintenance of location GO:0051235 89 0.011
regulation of neuron differentiation GO:0045664 281 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
striated muscle tissue development GO:0014706 293 0.011
regulation of intracellular transport GO:0032386 159 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
sulfur compound biosynthetic process GO:0044272 37 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of proteolysis GO:0030162 164 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
carboxylic acid transport GO:0046942 100 0.011
regulation of protein kinase activity GO:0045859 232 0.011
lymphocyte differentiation GO:0030098 242 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
covalent chromatin modification GO:0016569 163 0.011
cellular response to lipid GO:0071396 145 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
regulation of protein catabolic process GO:0042176 108 0.011
neuron death GO:0070997 154 0.011
organic anion transport GO:0015711 137 0.011
regulation of secretion GO:0051046 274 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
protein localization to organelle GO:0033365 185 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
locomotory behavior GO:0007626 195 0.010
regulation of kinase activity GO:0043549 249 0.010
innate immune response GO:0045087 157 0.010
macromolecule catabolic process GO:0009057 281 0.010
tetrapyrrole metabolic process GO:0033013 22 0.010
protein targeting GO:0006605 143 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
placenta development GO:0001890 140 0.010
transmission of nerve impulse GO:0019226 76 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
microtubule based process GO:0007017 236 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
regulation of response to wounding GO:1903034 189 0.010
cellular lipid catabolic process GO:0044242 52 0.010
positive regulation of kinase activity GO:0033674 155 0.010
protein processing GO:0016485 163 0.010
lipid homeostasis GO:0055088 63 0.010
alpha amino acid metabolic process GO:1901605 59 0.010

Txnrd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.026
central nervous system disease DOID:331 0 0.016
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
neurodegenerative disease DOID:1289 0 0.010