Mus musculus

174 known processes

Cln3

ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

(Aliases: AI323623)

Cln3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.176
ion transmembrane transport GO:0034220 361 0.121
regulation of defense response GO:0031347 233 0.110
immune effector process GO:0002252 321 0.109
cation transmembrane transport GO:0098655 266 0.108
ras protein signal transduction GO:0007265 77 0.098
amine metabolic process GO:0009308 45 0.095
cellular amine metabolic process GO:0044106 44 0.092
regulation of hydrolase activity GO:0051336 246 0.091
anion transport GO:0006820 177 0.089
cation transport GO:0006812 399 0.087
negative regulation of protein metabolic process GO:0051248 282 0.079
negative regulation of molecular function GO:0044092 258 0.078
vacuole organization GO:0007033 38 0.073
negative regulation of phosphate metabolic process GO:0045936 184 0.073
regulation of body fluid levels GO:0050878 162 0.072
regulation of cell activation GO:0050865 289 0.069
inorganic cation transmembrane transport GO:0098662 207 0.065
negative regulation of phosphorus metabolic process GO:0010563 184 0.065
cellular homeostasis GO:0019725 240 0.063
rho protein signal transduction GO:0007266 32 0.063
regulation of cellular catabolic process GO:0031329 242 0.062
cation homeostasis GO:0055080 212 0.061
cellular amino acid metabolic process GO:0006520 103 0.060
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.060
regulation of protein localization GO:0032880 231 0.060
lysosome organization GO:0007040 21 0.059
regulation of transferase activity GO:0051338 263 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.057
regulation of kinase activity GO:0043549 249 0.057
positive regulation of cellular amine metabolic process GO:0033240 5 0.056
macromolecule catabolic process GO:0009057 281 0.056
multicellular organismal homeostasis GO:0048871 164 0.055
regulation of cellular amine metabolic process GO:0033238 20 0.055
divalent inorganic cation transport GO:0072511 178 0.055
nucleoside phosphate metabolic process GO:0006753 338 0.053
peptidyl amino acid modification GO:0018193 336 0.053
aromatic compound catabolic process GO:0019439 286 0.052
nucleobase containing small molecule metabolic process GO:0055086 352 0.049
organonitrogen compound catabolic process GO:1901565 264 0.048
cellular lipid metabolic process GO:0044255 323 0.047
response to molecule of bacterial origin GO:0002237 143 0.047
protein modification by small protein conjugation GO:0032446 187 0.047
inorganic ion transmembrane transport GO:0098660 234 0.047
organic anion transport GO:0015711 137 0.046
positive regulation of protein modification process GO:0031401 299 0.045
regulation of secretion by cell GO:1903530 249 0.045
purine ribonucleoside metabolic process GO:0046128 241 0.045
negative regulation of cellular component organization GO:0051129 194 0.044
dephosphorylation GO:0016311 129 0.042
lytic vacuole organization GO:0080171 21 0.042
organic hydroxy compound transport GO:0015850 93 0.042
nucleotide metabolic process GO:0009117 332 0.042
regulation of ion transport GO:0043269 215 0.041
organonitrogen compound biosynthetic process GO:1901566 192 0.041
calcium ion transport GO:0006816 159 0.041
carbohydrate derivative catabolic process GO:1901136 231 0.041
protein catabolic process GO:0030163 221 0.040
nucleoside metabolic process GO:0009116 246 0.040
defense response to other organism GO:0098542 197 0.040
glycosyl compound metabolic process GO:1901657 246 0.040
regulation of response to wounding GO:1903034 189 0.040
posttranscriptional regulation of gene expression GO:0010608 155 0.040
g protein coupled receptor signaling pathway GO:0007186 243 0.039
cellular chemical homeostasis GO:0055082 215 0.039
regulation of protein transport GO:0051223 163 0.039
cellular ketone metabolic process GO:0042180 84 0.039
t cell activation GO:0042110 289 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
regulation of cytokine production GO:0001817 266 0.038
carbohydrate derivative biosynthetic process GO:1901137 183 0.037
cell type specific apoptotic process GO:0097285 268 0.037
response to lipopolysaccharide GO:0032496 128 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
response to organonitrogen compound GO:0010243 246 0.037
negative regulation of phosphorylation GO:0042326 166 0.037
purine nucleoside triphosphate catabolic process GO:0009146 203 0.037
regulation of secretion GO:0051046 274 0.036
organic hydroxy compound metabolic process GO:1901615 203 0.036
regionalization GO:0003002 337 0.036
nitrogen compound transport GO:0071705 271 0.035
regulation of establishment of protein localization GO:0070201 181 0.034
heterocycle catabolic process GO:0046700 280 0.034
nucleoside catabolic process GO:0009164 206 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
regulation of hormone levels GO:0010817 211 0.034
locomotory behavior GO:0007626 195 0.033
immune response regulating signaling pathway GO:0002764 125 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
guanosine containing compound metabolic process GO:1901068 144 0.033
protein secretion GO:0009306 111 0.033
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
regulation of cell motility GO:2000145 236 0.031
cytokine production GO:0001816 319 0.031
apoptotic signaling pathway GO:0097190 306 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
negative regulation of cell proliferation GO:0008285 296 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
phospholipid transfer to membrane GO:0006649 2 0.030
positive regulation of kinase activity GO:0033674 155 0.030
negative regulation of hydrolase activity GO:0051346 71 0.030
maintenance of location GO:0051235 89 0.030
endocytosis GO:0006897 168 0.030
positive regulation of cell activation GO:0050867 158 0.030
actin cytoskeleton organization GO:0030036 220 0.029
learning or memory GO:0007611 148 0.029
regulation of ras protein signal transduction GO:0046578 114 0.029
purine containing compound catabolic process GO:0072523 213 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
cellular response to dna damage stimulus GO:0006974 207 0.029
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.029
gtp metabolic process GO:0046039 144 0.029
positive regulation of transferase activity GO:0051347 167 0.029
cellular metal ion homeostasis GO:0006875 151 0.029
ribonucleotide catabolic process GO:0009261 208 0.028
alcohol metabolic process GO:0006066 116 0.028
gland development GO:0048732 330 0.028
regulation of protein kinase activity GO:0045859 232 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
innate immune response GO:0045087 157 0.028
reactive nitrogen species metabolic process GO:2001057 0 0.028
cellular response to lipid GO:0071396 145 0.028
negative regulation of cell development GO:0010721 169 0.028
regulation of anatomical structure size GO:0090066 178 0.028
cellular divalent inorganic cation homeostasis GO:0072503 127 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
blood circulation GO:0008015 195 0.027
purine containing compound metabolic process GO:0072521 311 0.027
carbohydrate metabolic process GO:0005975 230 0.027
nucleotide catabolic process GO:0009166 217 0.027
circulatory system process GO:0003013 197 0.027
glycoprotein metabolic process GO:0009100 116 0.027
lipid localization GO:0010876 126 0.026
metal ion homeostasis GO:0055065 189 0.026
cellular response to lipopolysaccharide GO:0071222 77 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
positive regulation of rho gtpase activity GO:0032321 41 0.026
cellular ion homeostasis GO:0006873 165 0.026
mapk cascade GO:0000165 281 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
protein processing GO:0016485 163 0.026
cognition GO:0050890 149 0.026
purine nucleoside catabolic process GO:0006152 205 0.025
regulation of organelle organization GO:0033043 289 0.025
regulation of mapk cascade GO:0043408 248 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
regulation of gtp catabolic process GO:0033124 113 0.025
protein ubiquitination GO:0016567 171 0.025
lipid biosynthetic process GO:0008610 179 0.025
regulation of map kinase activity GO:0043405 120 0.024
regulation of ras gtpase activity GO:0032318 88 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
protein maturation GO:0051604 176 0.023
organophosphate catabolic process GO:0046434 232 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
leukocyte differentiation GO:0002521 342 0.023
gtp catabolic process GO:0006184 143 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
regulation of rho gtpase activity GO:0032319 58 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
adaptive immune response GO:0002250 155 0.023
regulation of proteolysis GO:0030162 164 0.023
activation of immune response GO:0002253 138 0.023
regulation of protein serine threonine kinase activity GO:0071900 157 0.023
regulation of cell adhesion GO:0030155 154 0.023
reactive oxygen species biosynthetic process GO:1903409 8 0.023
cytoplasmic transport GO:0016482 234 0.022
regulation of protein catabolic process GO:0042176 108 0.022
adult behavior GO:0030534 135 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
response to oxygen levels GO:0070482 62 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
skin development GO:0043588 220 0.022
lipid transport GO:0006869 98 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
response to peptide GO:1901652 136 0.022
covalent chromatin modification GO:0016569 163 0.022
forebrain development GO:0030900 302 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
muscle system process GO:0003012 141 0.022
i kappab kinase nf kappab signaling GO:0007249 85 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
leukocyte mediated immunity GO:0002443 174 0.021
muscle cell differentiation GO:0042692 261 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
nuclear transport GO:0051169 139 0.021
negative regulation of cytokine production GO:0001818 84 0.021
response to acid chemical GO:0001101 111 0.021
positive regulation of gtpase activity GO:0043547 85 0.021
positive regulation of gtp catabolic process GO:0033126 85 0.021
negative regulation of nervous system development GO:0051961 156 0.021
positive regulation of protein transport GO:0051222 93 0.021
regulation of protein secretion GO:0050708 82 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
leukocyte activation involved in immune response GO:0002366 126 0.020
sphingolipid metabolic process GO:0006665 45 0.020
positive regulation of cytokine production GO:0001819 174 0.020
lymphocyte activation involved in immune response GO:0002285 93 0.020
protein localization to organelle GO:0033365 185 0.020
lymphocyte proliferation GO:0046651 164 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
protein localization to nucleus GO:0034504 121 0.020
skeletal system development GO:0001501 356 0.020
ameboidal type cell migration GO:0001667 128 0.020
regulation of cell migration GO:0030334 219 0.020
sequestering of calcium ion GO:0051208 18 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of calcium ion transport GO:0051924 69 0.020
histone modification GO:0016570 159 0.019
negative regulation of organelle organization GO:0010639 90 0.019
organelle localization GO:0051640 179 0.019
positive regulation of secretion by cell GO:1903532 114 0.019
muscle cell development GO:0055001 133 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
lymphocyte differentiation GO:0030098 242 0.019
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
sensory perception of sound GO:0007605 97 0.019
myosin filament assembly GO:0031034 2 0.019
wound healing GO:0042060 157 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
response to extracellular stimulus GO:0009991 127 0.018
regulation of cell projection organization GO:0031344 206 0.018
peptide transport GO:0015833 133 0.018
response to inorganic substance GO:0010035 96 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
negative regulation of cell activation GO:0050866 111 0.018
protein targeting GO:0006605 143 0.018
amino acid transport GO:0006865 61 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
organic acid transport GO:0015849 101 0.018
cofactor transport GO:0051181 4 0.018
response to radiation GO:0009314 165 0.018
sensory perception GO:0007600 245 0.018
organelle assembly GO:0070925 177 0.018
negative regulation of protein modification process GO:0031400 163 0.018
heart process GO:0003015 94 0.018
oxidation reduction process GO:0055114 342 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
toll like receptor signaling pathway GO:0002224 38 0.018
microtubule based process GO:0007017 236 0.018
macromolecule glycosylation GO:0043413 55 0.017
response to light stimulus GO:0009416 135 0.017
intracellular protein transport GO:0006886 204 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
negative regulation of transferase activity GO:0051348 85 0.017
ossification GO:0001503 216 0.017
tissue homeostasis GO:0001894 115 0.017
regulation of inflammatory response GO:0050727 147 0.017
hemostasis GO:0007599 78 0.017
carbohydrate homeostasis GO:0033500 128 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
morphogenesis of a branching structure GO:0001763 203 0.016
neural precursor cell proliferation GO:0061351 121 0.016
negative regulation of defense response GO:0031348 77 0.016
endomembrane system organization GO:0010256 147 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
organophosphate ester transport GO:0015748 28 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
male gamete generation GO:0048232 285 0.016
body fluid secretion GO:0007589 53 0.016
lipoprotein metabolic process GO:0042157 43 0.016
regulation of system process GO:0044057 200 0.016
positive regulation of secretion GO:0051047 130 0.016
protein glycosylation GO:0006486 55 0.016
germ cell development GO:0007281 185 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
anion transmembrane transport GO:0098656 71 0.016
myosin filament organization GO:0031033 3 0.016
regulation of blood pressure GO:0008217 93 0.016
single organism cell adhesion GO:0098602 156 0.016
carboxylic acid transport GO:0046942 100 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
bone remodeling GO:0046849 53 0.016
small molecule biosynthetic process GO:0044283 132 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
organic hydroxy compound biosynthetic process GO:1901617 77 0.016
spermatogenesis GO:0007283 284 0.016
leukocyte proliferation GO:0070661 172 0.015
regulation of peptidase activity GO:0052547 96 0.015
chromatin organization GO:0006325 206 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
tube formation GO:0035148 140 0.015
hormone secretion GO:0046879 128 0.015
pallium development GO:0021543 120 0.015
divalent metal ion transport GO:0070838 172 0.015
anatomical structure homeostasis GO:0060249 145 0.015
viral process GO:0016032 41 0.015
neural tube formation GO:0001841 108 0.015
membrane lipid biosynthetic process GO:0046467 32 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
response to starvation GO:0042594 65 0.015
immune response activating signal transduction GO:0002757 116 0.015
response to peptide hormone GO:0043434 127 0.015
protein autophosphorylation GO:0046777 61 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
response to oxidative stress GO:0006979 123 0.015
negative regulation of response to wounding GO:1903035 77 0.015
interleukin 8 production GO:0032637 4 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
regulation of neuron apoptotic process GO:0043523 122 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of cell cycle GO:0051726 281 0.014
tissue remodeling GO:0048771 102 0.014
actin filament organization GO:0007015 113 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
negative regulation of immune system process GO:0002683 209 0.014
lymphocyte apoptotic process GO:0070227 54 0.014
regulation of blood circulation GO:1903522 93 0.014
visual behavior GO:0007632 45 0.014
sphingolipid biosynthetic process GO:0030148 26 0.014
cellular response to acid chemical GO:0071229 68 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.014
calcium ion transmembrane transport GO:0070588 85 0.014
positive regulation of defense response GO:0031349 124 0.014
operant conditioning GO:0035106 2 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
fatty acid metabolic process GO:0006631 121 0.014
transition metal ion transport GO:0000041 38 0.014
negative regulation of mapk cascade GO:0043409 65 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
skeletal system morphogenesis GO:0048705 203 0.014
neural tube development GO:0021915 160 0.014
negative regulation of proteolysis GO:0045861 74 0.014
striated muscle myosin thick filament assembly GO:0071688 1 0.014
rhythmic process GO:0048511 174 0.014
peptide metabolic process GO:0006518 46 0.014
synaptic transmission GO:0007268 329 0.014
regulation of nuclear division GO:0051783 56 0.013
lipid homeostasis GO:0055088 63 0.013
cell maturation GO:0048469 127 0.013
positive regulation of innate immune response GO:0045089 80 0.013
positive regulation of ion transport GO:0043270 65 0.013
negative regulation of protein maturation GO:1903318 79 0.013
regulation of cell substrate adhesion GO:0010810 73 0.013
adult locomotory behavior GO:0008344 91 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
positive regulation of proteolysis GO:0045862 85 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
vesicle organization GO:0016050 60 0.013
response to monosaccharide GO:0034284 67 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
cell adhesion GO:0007155 329 0.013
regulation of hormone secretion GO:0046883 88 0.013
epithelial cell proliferation GO:0050673 174 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
regulation of homeostatic process GO:0032844 182 0.013
ceramide biosynthetic process GO:0046513 20 0.013
dna metabolic process GO:0006259 303 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
pattern recognition receptor signaling pathway GO:0002221 47 0.013
negative regulation of multi organism process GO:0043901 68 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
cell activation involved in immune response GO:0002263 126 0.013
oocyte axis specification GO:0007309 2 0.013
telencephalon development GO:0021537 186 0.012
homeostasis of number of cells GO:0048872 210 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
segmentation GO:0035282 93 0.012
negative regulation of protein processing GO:0010955 79 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
epidermis development GO:0008544 187 0.012
lipid catabolic process GO:0016042 69 0.012
macromolecule methylation GO:0043414 120 0.012
cholesterol transport GO:0030301 38 0.012
membrane lipid metabolic process GO:0006643 53 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
epithelial tube formation GO:0072175 130 0.012
protein alkylation GO:0008213 81 0.012
plasma membrane organization GO:0007009 90 0.012
cellular amide metabolic process GO:0043603 58 0.012
protein import into nucleus GO:0006606 95 0.012
regulation of transmembrane transport GO:0034762 128 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
ceramide metabolic process GO:0006672 31 0.012
chromatin modification GO:0016568 187 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
regulation of intracellular transport GO:0032386 159 0.012
epithelial cell development GO:0002064 159 0.012
glucose transport GO:0015758 56 0.012
heart contraction GO:0060047 93 0.012
protein methylation GO:0006479 81 0.012
t cell differentiation GO:0030217 174 0.012
positive regulation of cell death GO:0010942 224 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of cellular component size GO:0032535 121 0.012
organelle fission GO:0048285 170 0.012
negative regulation of kinase activity GO:0033673 81 0.012
regulation of multi organism process GO:0043900 111 0.012
Worm
coagulation GO:0050817 78 0.012
neurotransmitter transport GO:0006836 76 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
camera type eye development GO:0043010 266 0.012
glycosylation GO:0070085 62 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
cellular response to peptide GO:1901653 92 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
amide transport GO:0042886 138 0.012
alpha beta t cell activation GO:0046631 91 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
interleukin 6 production GO:0032635 58 0.012
calcium ion homeostasis GO:0055074 127 0.011
nuclear import GO:0051170 95 0.011
negative regulation of secretion GO:0051048 61 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
muscle tissue development GO:0060537 308 0.011
glucose homeostasis GO:0042593 128 0.011
response to insulin GO:0032868 100 0.011
insulin secretion GO:0030073 89 0.011
mesoderm development GO:0007498 100 0.011
interspecies interaction between organisms GO:0044419 83 0.011
stem cell development GO:0048864 219 0.011
positive regulation of interleukin 8 production GO:0032757 2 0.011
peptide hormone secretion GO:0030072 109 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
lipoprotein biosynthetic process GO:0042158 33 0.011
cytokine secretion GO:0050663 72 0.011
carbohydrate transport GO:0008643 62 0.011
neuron projection extension GO:1990138 64 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
lateral inhibition GO:0046331 1 0.011
ral protein signal transduction GO:0032484 2 0.011
stem cell differentiation GO:0048863 268 0.011
compound eye development GO:0048749 1 0.011
sensory system development GO:0048880 3 0.011
regulation of cell growth GO:0001558 91 0.011
membrane organization GO:0061024 245 0.011
muscle contraction GO:0006936 101 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
sterol transport GO:0015918 38 0.011
retina development in camera type eye GO:0060041 119 0.011
negative regulation of inflammatory response GO:0050728 61 0.011
establishment of organelle localization GO:0051656 122 0.011
protein oligomerization GO:0051259 67 0.011
monosaccharide metabolic process GO:0005996 106 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
t cell proliferation GO:0042098 120 0.011
response to organic cyclic compound GO:0014070 198 0.011
ear development GO:0043583 200 0.011
regulation of neuron death GO:1901214 134 0.011
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
regulation of t cell mediated immunity GO:0002709 34 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
actin filament bundle assembly GO:0051017 40 0.011
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.011
regulation of interleukin 1 alpha production GO:0032650 4 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011

Cln3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.038
inherited metabolic disorder DOID:655 0 0.035
central nervous system disease DOID:331 0 0.026
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011