Mus musculus

59 known processes

Siglece

sialic acid binding Ig-like lectin E

(Aliases: mSiglec-E,Cd170,Siglecl1,Siglec12,Siglec9,Siglec5)

Siglece biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.928
immune response activating signal transduction GO:0002757 116 0.656
regulation of cell activation GO:0050865 289 0.648
cellular response to peptidoglycan GO:0071224 4 0.615
cytokine production GO:0001816 319 0.574
negative regulation of immune system process GO:0002683 209 0.492
immune effector process GO:0002252 321 0.487
leukocyte mediated immunity GO:0002443 174 0.464
interleukin 18 production GO:0032621 4 0.459
positive regulation of protein modification process GO:0031401 299 0.408
serotonin secretion by mast cell GO:0002552 1 0.384
leukocyte migration GO:0050900 124 0.375
defense response to bacterium GO:0042742 119 0.348
cytokine production involved in immune response GO:0002367 34 0.327
positive regulation of cytokine production GO:0001819 174 0.320
toll like receptor signaling pathway GO:0002224 38 0.315
regulation of vesicle mediated transport GO:0060627 139 0.312
regulation of leukocyte mediated immunity GO:0002703 104 0.309
negative regulation of mast cell degranulation GO:0043305 4 0.301
regulation of mast cell activation GO:0033003 21 0.275
leukocyte activation involved in immune response GO:0002366 126 0.274
activation of innate immune response GO:0002218 56 0.273
production of molecular mediator of immune response GO:0002440 103 0.247
activation of immune response GO:0002253 138 0.239
negative regulation of serotonin secretion GO:0014063 2 0.239
neutrophil chemotaxis GO:0030593 36 0.230
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.228
regulation of cell migration GO:0030334 219 0.214
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.212
leukocyte differentiation GO:0002521 342 0.210
positive regulation of innate immune response GO:0045089 80 0.203
immune response regulating signaling pathway GO:0002764 125 0.197
regulation of secretion by cell GO:1903530 249 0.196
lymphocyte mediated immunity GO:0002449 139 0.184
regulation of lymphocyte mediated immunity GO:0002706 84 0.172
regulation of innate immune response GO:0045088 91 0.171
regulation of secretion GO:0051046 274 0.166
detection of fungus GO:0016046 2 0.165
positive regulation of leukocyte mediated immunity GO:0002705 70 0.164
mast cell activation GO:0045576 27 0.164
cell chemotaxis GO:0060326 81 0.161
detection of molecule of bacterial origin GO:0032490 2 0.159
regulation of response to wounding GO:1903034 189 0.158
negative regulation of leukocyte mediated immunity GO:0002704 29 0.153
regulation of protein localization GO:0032880 231 0.147
regulation of establishment of protein localization GO:0070201 181 0.145
response to lipopolysaccharide GO:0032496 128 0.144
positive regulation of immune effector process GO:0002699 107 0.143
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.141
regulation of cytokine production GO:0001817 266 0.140
granulocyte migration GO:0097530 43 0.139
positive regulation of defense response GO:0031349 124 0.139
cellular response to lipopolysaccharide GO:0071222 77 0.139
innate immune response GO:0045087 157 0.137
positive regulation of protein phosphorylation GO:0001934 242 0.136
serotonin production involved in inflammatory response GO:0002351 4 0.132
pattern recognition receptor signaling pathway GO:0002221 47 0.131
detection of peptidoglycan GO:0032499 1 0.130
positive regulation of protein transport GO:0051222 93 0.128
defense response to gram positive bacterium GO:0050830 50 0.125
mast cell activation involved in immune response GO:0002279 20 0.121
negative regulation of cytokine production GO:0001818 84 0.117
positive regulation of cellular amine metabolic process GO:0033240 5 0.117
myeloid leukocyte migration GO:0097529 57 0.117
positive regulation of interleukin 18 production GO:0032741 2 0.117
response to peptidoglycan GO:0032494 9 0.116
regulation of immunoglobulin mediated immune response GO:0002889 37 0.116
regulation of inflammatory response GO:0050727 147 0.115
t cell activation GO:0042110 289 0.114
innate immune response activating signal transduction GO:0002758 50 0.113
serotonin secretion involved in inflammatory response GO:0002442 4 0.111
keratinocyte migration GO:0051546 3 0.110
myeloid leukocyte activation GO:0002274 83 0.109
regulation of toll like receptor signaling pathway GO:0034121 20 0.109
t cell mediated immunity GO:0002456 50 0.108
activation of mapk activity involved in innate immune response GO:0035419 2 0.107
cellular calcium ion homeostasis GO:0006874 119 0.107
positive regulation of response to wounding GO:1903036 66 0.106
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.106
positive regulation of cytokine secretion GO:0050715 41 0.104
negative regulation of interleukin 5 production GO:0032714 4 0.104
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.102
cellular ketone metabolic process GO:0042180 84 0.099
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.098
negative regulation of interleukin 13 secretion GO:2000666 1 0.098
adaptive immune response GO:0002250 155 0.097
amine metabolic process GO:0009308 45 0.096
inflammatory response GO:0006954 244 0.095
peptidyl amino acid modification GO:0018193 336 0.093
cellular amino acid metabolic process GO:0006520 103 0.091
negative regulation of growth GO:0045926 99 0.090
nitrogen compound transport GO:0071705 271 0.090
positive regulation of cell migration GO:0030335 109 0.090
negative regulation of t cell mediated immunity GO:0002710 9 0.089
positive regulation of cell activation GO:0050867 158 0.088
positive regulation of protein secretion GO:0050714 52 0.087
regulation of lymphocyte activation GO:0051249 240 0.087
regulation of protein secretion GO:0050708 82 0.086
leukocyte chemotaxis GO:0030595 69 0.086
negative regulation of lymphocyte activation GO:0051250 91 0.085
positive regulation of map kinase activity GO:0043406 84 0.084
cell activation involved in immune response GO:0002263 126 0.083
positive regulation of secretion by cell GO:1903532 114 0.082
positive regulation of interferon alpha biosynthetic process GO:0045356 1 0.082
negative regulation of mast cell activation involved in immune response GO:0033007 5 0.081
g protein coupled receptor signaling pathway GO:0007186 243 0.081
i kappab kinase nf kappab signaling GO:0007249 85 0.081
regulation of cellular amine metabolic process GO:0033238 20 0.080
cellular amine metabolic process GO:0044106 44 0.079
myeloid cell differentiation GO:0030099 233 0.078
response to molecule of bacterial origin GO:0002237 143 0.077
interspecies interaction between organisms GO:0044419 83 0.076
positive regulation of cell motility GO:2000147 116 0.075
antibacterial peptide production GO:0002778 2 0.075
regulation of defense response GO:0031347 233 0.074
negative regulation of cell activation GO:0050866 111 0.073
cation homeostasis GO:0055080 212 0.073
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.073
toll like receptor 7 signaling pathway GO:0034154 4 0.073
cytokine biosynthetic process GO:0042089 68 0.073
cytokine secretion GO:0050663 72 0.072
protein secretion GO:0009306 111 0.071
rho protein signal transduction GO:0007266 32 0.070
negative regulation of adaptive immune response GO:0002820 25 0.070
peptidyl tyrosine modification GO:0018212 145 0.070
granulocyte chemotaxis GO:0071621 39 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.067
positive regulation of secretion GO:0051047 130 0.066
myeloid cell activation involved in immune response GO:0002275 34 0.066
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.066
negative regulation of mast cell activation GO:0033004 6 0.066
negative regulation of nik nf kappab signaling GO:1901223 2 0.065
calcium mediated signaling GO:0019722 46 0.065
defense response to virus GO:0051607 68 0.065
homeostasis of number of cells GO:0048872 210 0.063
positive regulation of cytokine production involved in immune response GO:0002720 19 0.063
activation of mapk activity GO:0000187 59 0.061
interleukin 5 secretion GO:0072603 2 0.061
interleukin 6 production GO:0032635 58 0.060
detection of biotic stimulus GO:0009595 10 0.059
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.059
sequestering of calcium ion GO:0051208 18 0.059
reactive oxygen species metabolic process GO:0072593 84 0.058
sensory perception GO:0007600 245 0.058
regulation of b cell mediated immunity GO:0002712 37 0.058
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.057
regulation of chemokine production GO:0032642 30 0.057
negative regulation of leukocyte proliferation GO:0070664 46 0.057
lymphocyte activation involved in immune response GO:0002285 93 0.057
regulation of erk1 and erk2 cascade GO:0070372 71 0.056
nucleoside triphosphate metabolic process GO:0009141 230 0.055
myeloid leukocyte differentiation GO:0002573 119 0.055
small gtpase mediated signal transduction GO:0007264 97 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.055
inorganic ion transmembrane transport GO:0098660 234 0.054
regulation of adaptive immune response GO:0002819 90 0.053
regulation of body fluid levels GO:0050878 162 0.053
interleukin 13 secretion GO:0072611 2 0.053
cation transport GO:0006812 399 0.052
myeloid leukocyte mediated immunity GO:0002444 42 0.051
cellular response to organonitrogen compound GO:0071417 145 0.051
neutrophil migration GO:1990266 37 0.051
negative regulation of interleukin 10 secretion GO:2001180 2 0.051
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.050
negative regulation of interleukin 13 production GO:0032696 2 0.050
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.050
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.050
ras protein signal transduction GO:0007265 77 0.049
regulation of interleukin 8 production GO:0032677 3 0.048
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.048
regulation of cell motility GO:2000145 236 0.048
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.048
exocytosis GO:0006887 121 0.048
cytokine metabolic process GO:0042107 71 0.047
regulation of interleukin 13 secretion GO:2000665 2 0.047
regulation of protein transport GO:0051223 163 0.047
chemotaxis GO:0006935 247 0.047
negative regulation of immune effector process GO:0002698 55 0.046
cellular response to molecule of bacterial origin GO:0071219 83 0.046
positive regulation of phagocytosis GO:0050766 26 0.045
regulation of cellular response to stress GO:0080135 159 0.045
toll like receptor 2 signaling pathway GO:0034134 6 0.045
response to organic cyclic compound GO:0014070 198 0.045
regulation of mast cell degranulation GO:0043304 16 0.045
calcium ion homeostasis GO:0055074 127 0.045
cellular response to cytokine stimulus GO:0071345 189 0.044
regulation of map kinase activity GO:0043405 120 0.044
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.044
gliogenesis GO:0042063 141 0.044
negative regulation of secretion by cell GO:1903531 54 0.043
purine containing compound catabolic process GO:0072523 213 0.043
histamine production involved in inflammatory response GO:0002349 1 0.043
cation transmembrane transport GO:0098655 266 0.043
growth of symbiont in host GO:0044117 23 0.042
regulation of hormone levels GO:0010817 211 0.042
regulation of production of molecular mediator of immune response GO:0002700 65 0.041
regulation of t cell proliferation GO:0042129 92 0.041
leukocyte proliferation GO:0070661 172 0.041
sequestering of metal ion GO:0051238 19 0.041
endocytosis GO:0006897 168 0.041
cell recognition GO:0008037 83 0.040
stress activated protein kinase signaling cascade GO:0031098 81 0.040
ribonucleoside triphosphate catabolic process GO:0009203 199 0.040
membrane organization GO:0061024 245 0.040
cellular metal ion homeostasis GO:0006875 151 0.039
serotonin transport GO:0006837 11 0.039
antibacterial peptide biosynthetic process GO:0002780 2 0.039
detection of bacterium GO:0016045 7 0.038
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.038
immunoglobulin mediated immune response GO:0016064 69 0.038
detection of yeast GO:0001879 2 0.038
t cell proliferation GO:0042098 120 0.038
mapk cascade GO:0000165 281 0.038
humoral immune response GO:0006959 57 0.038
regulation of cytokine secretion GO:0050707 61 0.038
positive regulation of transferase activity GO:0051347 167 0.038
cellular ion homeostasis GO:0006873 165 0.038
negative regulation of t cell proliferation GO:0042130 38 0.037
regulation of protein kinase activity GO:0045859 232 0.037
regulation of calcium ion transport into cytosol GO:0010522 31 0.037
b cell activation involved in immune response GO:0002312 50 0.037
regulation of interleukin 5 secretion GO:2000662 2 0.037
ion transmembrane transport GO:0034220 361 0.037
regulation of antimicrobial humoral response GO:0002759 3 0.037
interleukin 12 production GO:0032615 32 0.037
negative regulation of interleukin 5 secretion GO:2000663 1 0.037
histamine transport GO:0051608 2 0.037
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.036
regulation of phagocytosis GO:0050764 33 0.036
positive regulation of endocytosis GO:0045807 42 0.036
alpha beta t cell activation GO:0046631 91 0.036
reactive oxygen species biosynthetic process GO:1903409 8 0.036
regulation of interleukin 18 production GO:0032661 3 0.035
organic hydroxy compound transport GO:0015850 93 0.035
cellular carbohydrate metabolic process GO:0044262 119 0.035
eosinophil migration GO:0072677 3 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
cellular response to biotic stimulus GO:0071216 92 0.035
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.035
regulation of serotonin secretion GO:0014062 3 0.034
second messenger mediated signaling GO:0019932 73 0.034
immunoglobulin production GO:0002377 73 0.034
erk1 and erk2 cascade GO:0070371 77 0.034
negative regulation of t cell activation GO:0050868 65 0.034
response to growth factor GO:0070848 198 0.033
protein catabolic process GO:0030163 221 0.033
nucleotide metabolic process GO:0009117 332 0.033
phosphatidylinositol mediated signaling GO:0048015 41 0.033
antimicrobial peptide production GO:0002775 2 0.032
positive regulation of b cell mediated immunity GO:0002714 26 0.032
growth involved in symbiotic interaction GO:0044110 23 0.032
regulation of t cell differentiation GO:0045580 83 0.032
negative regulation of cell proliferation GO:0008285 296 0.032
multicellular organismal homeostasis GO:0048871 164 0.032
monoamine transport GO:0015844 33 0.032
response to organonitrogen compound GO:0010243 246 0.032
negative regulation of secretion GO:0051048 61 0.032
protein kinase b signaling GO:0043491 74 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
phagocytosis GO:0006909 66 0.032
lymphocyte proliferation GO:0046651 164 0.032
organ or tissue specific immune response GO:0002251 13 0.031
histamine secretion by mast cell GO:0002553 1 0.031
lysosome localization GO:0032418 20 0.031
detection of external biotic stimulus GO:0098581 9 0.031
regulation of kinase activity GO:0043549 249 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
aromatic compound catabolic process GO:0019439 286 0.031
regulation of interleukin 6 production GO:0032675 55 0.031
positive regulation of interferon alpha production GO:0032727 4 0.031
macromolecule catabolic process GO:0009057 281 0.030
b cell mediated immunity GO:0019724 71 0.030
b cell activation GO:0042113 161 0.030
divalent inorganic cation transport GO:0072511 178 0.030
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.030
regulation of cytokine production involved in immune response GO:0002718 26 0.030
inorganic cation transmembrane transport GO:0098662 207 0.030
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.030
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.030
negative regulation of lymphocyte proliferation GO:0050672 45 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
positive regulation of stress activated mapk cascade GO:0032874 48 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
regulation of t cell activation GO:0050863 170 0.029
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.029
mast cell mediated immunity GO:0002448 20 0.029
detection of stimulus GO:0051606 84 0.029
positive regulation of t cell activation GO:0050870 101 0.029
positive regulation of interleukin 8 production GO:0032757 2 0.028
regulation of interleukin 10 secretion GO:2001179 4 0.028
circulatory system process GO:0003013 197 0.028
positive regulation of intracellular transport GO:0032388 70 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
body fluid secretion GO:0007589 53 0.028
modification of morphology or physiology of other organism GO:0035821 18 0.028
negative regulation of protein secretion GO:0050709 20 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
defense response to gram negative bacterium GO:0050829 28 0.028
negative regulation of interleukin 12 production GO:0032695 10 0.028
positive regulation of thymocyte migration GO:2000412 2 0.028
notch signaling pathway GO:0007219 71 0.028
thymocyte migration GO:0072679 2 0.028
regulation of immunoglobulin production GO:0002637 42 0.028
regulation of mapk cascade GO:0043408 248 0.027
reactive nitrogen species metabolic process GO:2001057 0 0.027
regulation of cytokine biosynthetic process GO:0042035 59 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
regulation of neutrophil migration GO:1902622 14 0.027
interleukin 8 production GO:0032637 4 0.027
maintenance of location GO:0051235 89 0.027
regulation of system process GO:0044057 200 0.027
organelle localization GO:0051640 179 0.027
response to acid chemical GO:0001101 111 0.027
positive regulation of cytokine biosynthetic process GO:0042108 40 0.027
negative regulation of multi organism process GO:0043901 68 0.027
positive regulation of protein kinase activity GO:0045860 144 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.026
heterocycle catabolic process GO:0046700 280 0.026
cellular lipid metabolic process GO:0044255 323 0.026
regulation of intracellular transport GO:0032386 159 0.026
antigen receptor mediated signaling pathway GO:0050851 64 0.026
detection of lipoteichoic acid GO:0070392 1 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
myeloid dendritic cell differentiation GO:0043011 16 0.025
positive regulation of adaptive immune response GO:0002821 61 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.025
angiogenesis GO:0001525 201 0.025
intracellular protein transport GO:0006886 204 0.025
purine containing compound metabolic process GO:0072521 311 0.025
regulation of tumor necrosis factor production GO:0032680 49 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
interferon gamma production GO:0032609 67 0.025
actin cytoskeleton organization GO:0030036 220 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
regulation of stress activated mapk cascade GO:0032872 69 0.025
negative regulation of phagocytosis GO:0050765 4 0.025
circadian temperature homeostasis GO:0060086 2 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
cell adhesion GO:0007155 329 0.025
tissue homeostasis GO:0001894 115 0.025
positive regulation of interleukin 6 production GO:0032755 37 0.024
t helper 1 cell cytokine production GO:0035744 1 0.024
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.024
regulation of antibacterial peptide production GO:0002786 1 0.024
regulation of endocytosis GO:0030100 69 0.024
asymmetric stem cell division GO:0098722 3 0.024
positive regulation of neutrophil chemotaxis GO:0090023 12 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.024
regulation of interleukin 12 production GO:0032655 30 0.024
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
regulation of t cell mediated immunity GO:0002709 34 0.023
stress activated mapk cascade GO:0051403 80 0.023
purinergic receptor signaling pathway GO:0035587 7 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
somatic diversification of immune receptors GO:0002200 53 0.023
interferon alpha biosynthetic process GO:0045349 1 0.023
wound healing GO:0042060 157 0.023
anatomical structure homeostasis GO:0060249 145 0.023
lymphocyte differentiation GO:0030098 242 0.023
t cell differentiation GO:0030217 174 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
release of sequestered calcium ion into cytosol GO:0051209 42 0.023
regulation of neutrophil chemotaxis GO:0090022 14 0.023
microtubule based process GO:0007017 236 0.023
action potential GO:0001508 78 0.023
regulation of transferase activity GO:0051338 263 0.023
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.022
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
astrocyte cell migration GO:0043615 3 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
dendritic cell differentiation GO:0097028 26 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
positive regulation of ion transport GO:0043270 65 0.022
antibacterial peptide secretion GO:0002779 1 0.022
mucopolysaccharide metabolic process GO:1903510 25 0.022
neuronal action potential GO:0019228 54 0.022
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.022
antimicrobial peptide biosynthetic process GO:0002777 2 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
production of molecular mediator involved in inflammatory response GO:0002532 21 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
Mouse
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.021
cellular response to lipid GO:0071396 145 0.021
neutrophil mediated killing of bacterium GO:0070944 6 0.021
regulation of ion transport GO:0043269 215 0.021
positive regulation of kinase activity GO:0033674 155 0.021
regulation of protein ubiquitination GO:0031396 52 0.021
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
regulation of chemotaxis GO:0050920 53 0.021
regulation of cell shape GO:0008360 39 0.021
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.021
positive regulation of leukocyte proliferation GO:0070665 73 0.021
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 6 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
interferon beta biosynthetic process GO:0045350 4 0.021
sodium ion transport GO:0006814 73 0.021
cellular chemical homeostasis GO:0055082 215 0.020
positive regulation of tumor necrosis factor production GO:0032760 30 0.020
positive regulation of homeostatic process GO:0032846 64 0.020
regulation of t helper 2 cell cytokine production GO:2000551 3 0.020
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.020
cytosolic calcium ion homeostasis GO:0051480 70 0.020
positive regulation of defense response to bacterium GO:1900426 1 0.020
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
positive regulation of antimicrobial humoral response GO:0002760 2 0.020
ameboidal type cell migration GO:0001667 128 0.020
ensheathment of neurons GO:0007272 76 0.020
tissue remodeling GO:0048771 102 0.020
regulation of interleukin 10 production GO:0032653 21 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
regulation of lymphocyte proliferation GO:0050670 117 0.020
glial cell differentiation GO:0010001 131 0.020
glial cell apoptotic process GO:0034349 3 0.020
anion transport GO:0006820 177 0.020
regulation of multi organism process GO:0043900 111 0.020
intestinal epithelial structure maintenance GO:0060729 4 0.020
toll like receptor 9 signaling pathway GO:0034162 6 0.020
regulation of actin filament based process GO:0032970 99 0.020
positive regulation of lipid kinase activity GO:0090218 11 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
negative regulation of mapk cascade GO:0043409 65 0.019
negative regulation of protein transport GO:0051224 46 0.019
regulation of blood pressure GO:0008217 93 0.019
tumor necrosis factor production GO:0032640 50 0.019
oxidation reduction process GO:0055114 342 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
connective tissue development GO:0061448 179 0.019
nucleoside catabolic process GO:0009164 206 0.019
camera type eye development GO:0043010 266 0.019
establishment of organelle localization GO:0051656 122 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
chemokine metabolic process GO:0050755 10 0.019
positive regulation of leukocyte differentiation GO:1902107 86 0.019
cytokine mediated signaling pathway GO:0019221 115 0.019
carboxylic acid transport GO:0046942 100 0.019
lymphocyte migration GO:0072676 26 0.019
regulation of cytokine secretion involved in immune response GO:0002739 4 0.019
regulation of leukocyte apoptotic process GO:2000106 56 0.019
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.019
protein ubiquitination GO:0016567 171 0.018
regulation of ion homeostasis GO:2000021 64 0.018
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.018
positive regulation of calcium mediated signaling GO:0050850 15 0.018
dendritic cell migration GO:0036336 12 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
respiratory system development GO:0060541 190 0.018
positive regulation of protein ubiquitination GO:0031398 27 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.018
regulation of acute inflammatory response GO:0002673 27 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
response to dsrna GO:0043331 30 0.018
cellular homeostasis GO:0019725 240 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
mast cell degranulation GO:0043303 19 0.018
regulation of protein kinase b signaling GO:0051896 56 0.018
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.017
nucleoside metabolic process GO:0009116 246 0.017
response to drug GO:0042493 75 0.017
positive regulation of regulated secretory pathway GO:1903307 10 0.017
bone mineralization GO:0030282 54 0.017
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.017
nucleotide catabolic process GO:0009166 217 0.017
metal ion homeostasis GO:0055065 189 0.017
divalent metal ion transport GO:0070838 172 0.017
regulation of b cell activation GO:0050864 81 0.017
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.017
regulation of cell projection organization GO:0031344 206 0.017
gtp catabolic process GO:0006184 143 0.017
dna metabolic process GO:0006259 303 0.017
transmission of nerve impulse GO:0019226 76 0.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.016
regulation of growth of symbiont in host GO:0044126 19 0.016
cell type specific apoptotic process GO:0097285 268 0.016
regulation of mast cell activation involved in immune response GO:0033006 17 0.016
jnk cascade GO:0007254 72 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
protein polymerization GO:0051258 57 0.016
protein localization to organelle GO:0033365 185 0.016
inositol lipid mediated signaling GO:0048017 41 0.016
cellular amide metabolic process GO:0043603 58 0.016

Siglece disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
acquired immunodeficiency syndrome DOID:635 0 0.133
disease by infectious agent DOID:0050117 0 0.133
viral infectious disease DOID:934 0 0.133
human immunodeficiency virus infectious disease DOID:526 0 0.133