Mus musculus

0 known processes

Sgsm2

small G protein signaling modulator 2

(Aliases: Rutbc1,D630003G22Rik,mKIAA0397,R74628)

Sgsm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.111
transmembrane transport GO:0055085 412 0.093
nucleobase containing small molecule metabolic process GO:0055086 352 0.072
Human
purine ribonucleotide metabolic process GO:0009150 290 0.068
Human
nucleoside triphosphate metabolic process GO:0009141 230 0.060
Human
ribonucleotide catabolic process GO:0009261 208 0.059
Human
cellular amino acid metabolic process GO:0006520 103 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.054
Human
actin cytoskeleton organization GO:0030036 220 0.052
aromatic compound catabolic process GO:0019439 286 0.051
Human
inorganic ion transmembrane transport GO:0098660 234 0.051
membrane organization GO:0061024 245 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.048
negative regulation of cell proliferation GO:0008285 296 0.048
ras protein signal transduction GO:0007265 77 0.046
regulation of neuron projection development GO:0010975 169 0.045
purine containing compound metabolic process GO:0072521 311 0.045
Human
amine metabolic process GO:0009308 45 0.045
small gtpase mediated signal transduction GO:0007264 97 0.044
regulation of hydrolase activity GO:0051336 246 0.044
Human
cation transport GO:0006812 399 0.044
organonitrogen compound catabolic process GO:1901565 264 0.044
Human
ribose phosphate metabolic process GO:0019693 291 0.044
Human
cation transmembrane transport GO:0098655 266 0.042
rho protein signal transduction GO:0007266 32 0.042
inorganic cation transmembrane transport GO:0098662 207 0.041
glycosyl compound metabolic process GO:1901657 246 0.041
Human
cellular amine metabolic process GO:0044106 44 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.039
glycosyl compound catabolic process GO:1901658 206 0.039
Human
purine ribonucleoside catabolic process GO:0046130 205 0.039
Human
cellular ketone metabolic process GO:0042180 84 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
organic cyclic compound catabolic process GO:1901361 295 0.039
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
regulation of cellular component size GO:0032535 121 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
regulation of membrane potential GO:0042391 192 0.037
purine nucleotide catabolic process GO:0006195 211 0.036
Human
purine containing compound catabolic process GO:0072523 213 0.036
Human
nucleoside metabolic process GO:0009116 246 0.035
Human
regulation of cellular catabolic process GO:0031329 242 0.034
Human
nucleotide catabolic process GO:0009166 217 0.034
Human
regulation of kinase activity GO:0043549 249 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
Human
nucleoside phosphate metabolic process GO:0006753 338 0.032
Human
regulation of organelle organization GO:0033043 289 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
Human
spermatogenesis GO:0007283 284 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
Human
organophosphate catabolic process GO:0046434 232 0.031
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
Human
positive regulation of hydrolase activity GO:0051345 148 0.030
Human
purine ribonucleoside metabolic process GO:0046128 241 0.029
Human
g protein coupled receptor signaling pathway GO:0007186 243 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
Human
regulation of nucleoside metabolic process GO:0009118 130 0.029
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
Human
organic anion transport GO:0015711 137 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
Human
regulation of cell projection organization GO:0031344 206 0.027
respiratory system development GO:0060541 190 0.027
heterocycle catabolic process GO:0046700 280 0.027
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
Human
cellular lipid metabolic process GO:0044255 323 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
Human
positive regulation of ras gtpase activity GO:0032320 65 0.026
Human
negative regulation of protein metabolic process GO:0051248 282 0.026
positive regulation of cell development GO:0010720 237 0.026
positive regulation of protein modification process GO:0031401 299 0.025
nitrogen compound transport GO:0071705 271 0.025
apoptotic signaling pathway GO:0097190 306 0.025
macromolecule catabolic process GO:0009057 281 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.025
Human
positive regulation of cell projection organization GO:0031346 95 0.025
regulation of neuron differentiation GO:0045664 281 0.025
axonogenesis GO:0007409 274 0.025
cell type specific apoptotic process GO:0097285 268 0.025
microtubule based process GO:0007017 236 0.025
mapk cascade GO:0000165 281 0.024
anion transport GO:0006820 177 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
Human
carbohydrate derivative catabolic process GO:1901136 231 0.024
Human
multicellular organismal signaling GO:0035637 91 0.023
regulation of cell adhesion GO:0030155 154 0.023
nucleotide metabolic process GO:0009117 332 0.023
Human
ribonucleotide metabolic process GO:0009259 291 0.023
Human
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
Human
regulation of protein localization GO:0032880 231 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
regulation of transferase activity GO:0051338 263 0.022
oxidation reduction process GO:0055114 342 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
cellular homeostasis GO:0019725 240 0.022
regulation of cell activation GO:0050865 289 0.022
regulation of ion transport GO:0043269 215 0.022
regionalization GO:0003002 337 0.021
positive regulation of nervous system development GO:0051962 221 0.021
microtubule based movement GO:0007018 84 0.021
positive regulation of nucleotide catabolic process GO:0030813 88 0.021
Human
regulation of lymphocyte activation GO:0051249 240 0.021
gland development GO:0048732 330 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
Human
neuronal action potential GO:0019228 54 0.021
regulation of anatomical structure size GO:0090066 178 0.021
peptidyl amino acid modification GO:0018193 336 0.021
alcohol metabolic process GO:0006066 116 0.020
positive regulation of gtpase activity GO:0043547 85 0.020
Human
regulation of neuron death GO:1901214 134 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
Human
positive regulation of cellular catabolic process GO:0031331 148 0.020
Human
organelle assembly GO:0070925 177 0.020
small molecule biosynthetic process GO:0044283 132 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of cell migration GO:0030334 219 0.020
organelle localization GO:0051640 179 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
Human
reactive oxygen species biosynthetic process GO:1903409 8 0.020
cell adhesion GO:0007155 329 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
Human
regulation of transmembrane transport GO:0034762 128 0.019
sensory perception GO:0007600 245 0.019
forebrain development GO:0030900 302 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
Human
neural tube development GO:0021915 160 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.018
Human
transmission of nerve impulse GO:0019226 76 0.018
regulation of secretion GO:0051046 274 0.018
protein ubiquitination GO:0016567 171 0.018
response to organonitrogen compound GO:0010243 246 0.018
protein maturation GO:0051604 176 0.018
positive regulation of kinase activity GO:0033674 155 0.018
sensory organ morphogenesis GO:0090596 242 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
Human
regulation of ion transmembrane transport GO:0034765 119 0.018
lymphocyte differentiation GO:0030098 242 0.018
endocytosis GO:0006897 168 0.018
regulation of mapk cascade GO:0043408 248 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
neuron death GO:0070997 154 0.017
fertilization GO:0009566 127 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
nucleoside catabolic process GO:0009164 206 0.017
Human
regulation of system process GO:0044057 200 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
divalent inorganic cation transport GO:0072511 178 0.017
positive regulation of neuron projection development GO:0010976 79 0.017
action potential GO:0001508 78 0.017
microtubule cytoskeleton organization GO:0000226 157 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of secretion by cell GO:1903530 249 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
metal ion homeostasis GO:0055065 189 0.016
divalent metal ion transport GO:0070838 172 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
leukocyte differentiation GO:0002521 342 0.016
circulatory system process GO:0003013 197 0.016
immune effector process GO:0002252 321 0.016
primary neural tube formation GO:0014020 95 0.016
positive regulation of transferase activity GO:0051347 167 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
protein localization to membrane GO:0072657 108 0.016
regulation of proteolysis GO:0030162 164 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
Human
developmental maturation GO:0021700 193 0.016
negative regulation of immune system process GO:0002683 209 0.016
negative regulation of protein modification process GO:0031400 163 0.016
camera type eye development GO:0043010 266 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
glycerolipid metabolic process GO:0046486 122 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of protein kinase activity GO:0045859 232 0.015
actin filament organization GO:0007015 113 0.015
muscle system process GO:0003012 141 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
Human
positive regulation of leukocyte differentiation GO:1902107 86 0.015
skin development GO:0043588 220 0.015
respiratory tube development GO:0030323 167 0.015
skeletal system development GO:0001501 356 0.015
cell substrate adhesion GO:0031589 130 0.015
male gamete generation GO:0048232 285 0.015
dna metabolic process GO:0006259 303 0.015
adaptive immune response GO:0002250 155 0.015
learning or memory GO:0007611 148 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
Human
negative regulation of molecular function GO:0044092 258 0.015
t cell activation GO:0042110 289 0.015
dephosphorylation GO:0016311 129 0.015
regulation of cell cycle GO:0051726 281 0.015
inflammatory response GO:0006954 244 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
synaptic transmission GO:0007268 329 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
response to peptide hormone GO:0043434 127 0.014
cellular chemical homeostasis GO:0055082 215 0.014
lipid biosynthetic process GO:0008610 179 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
Human
gtp catabolic process GO:0006184 143 0.014
Human
reactive oxygen species metabolic process GO:0072593 84 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
cation homeostasis GO:0055080 212 0.014
connective tissue development GO:0061448 179 0.014
ossification GO:0001503 216 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
Human
t cell differentiation GO:0030217 174 0.013
response to light stimulus GO:0009416 135 0.013
pallium development GO:0021543 120 0.013
regulation of response to wounding GO:1903034 189 0.013
plasma membrane organization GO:0007009 90 0.013
endomembrane system organization GO:0010256 147 0.013
lipoprotein metabolic process GO:0042157 43 0.013
urogenital system development GO:0001655 261 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
regulation of cell size GO:0008361 72 0.013
cell growth GO:0016049 130 0.013
cognition GO:0050890 149 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
telencephalon development GO:0021537 186 0.013
response to lipopolysaccharide GO:0032496 128 0.013
organic acid transport GO:0015849 101 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of extent of cell growth GO:0061387 52 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
dendrite development GO:0016358 115 0.013
b cell activation GO:0042113 161 0.013
cell chemotaxis GO:0060326 81 0.013
vesicle organization GO:0016050 60 0.013
regulation of t cell activation GO:0050863 170 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
phospholipid metabolic process GO:0006644 87 0.012
calcium ion transport GO:0006816 159 0.012
regulation of homeostatic process GO:0032844 182 0.012
atp metabolic process GO:0046034 75 0.012
positive regulation of secretion GO:0051047 130 0.012
bone development GO:0060348 120 0.012
sequestering of metal ion GO:0051238 19 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
positive regulation of cell death GO:0010942 224 0.012
negative regulation of neuron differentiation GO:0045665 101 0.012
adult behavior GO:0030534 135 0.012
compound eye development GO:0048749 1 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
intracellular protein transport GO:0006886 204 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
protein targeting GO:0006605 143 0.012
angiogenesis GO:0001525 201 0.012
regulation of endocytosis GO:0030100 69 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
lymphocyte proliferation GO:0046651 164 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
response to organic cyclic compound GO:0014070 198 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
neural precursor cell proliferation GO:0061351 121 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
Human
cellular ion homeostasis GO:0006873 165 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
Human
regulation of cell motility GO:2000145 236 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
regulation of cytokine production GO:0001817 266 0.012
neuron apoptotic process GO:0051402 142 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
neural tube formation GO:0001841 108 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
negative regulation of nervous system development GO:0051961 156 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
calcium ion homeostasis GO:0055074 127 0.012
chemotaxis GO:0006935 247 0.012
protein catabolic process GO:0030163 221 0.012
lipid localization GO:0010876 126 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.011
rhythmic process GO:0048511 174 0.011
positive regulation of t cell activation GO:0050870 101 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
epithelial tube formation GO:0072175 130 0.011
actin filament polymerization GO:0030041 44 0.011
protein processing GO:0016485 163 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of inflammatory response GO:0050727 147 0.011
negative regulation of cell development GO:0010721 169 0.011
cytokine production GO:0001816 319 0.011
regulation of cellular response to stress GO:0080135 159 0.011
mitotic cell cycle GO:0000278 195 0.011
regulation of protein transport GO:0051223 163 0.011
kidney development GO:0001822 213 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of cell growth GO:0001558 91 0.011
response to growth factor GO:0070848 198 0.011
negative regulation of cell activation GO:0050866 111 0.011
muscle cell differentiation GO:0042692 261 0.011
ameboidal type cell migration GO:0001667 128 0.011
organic acid biosynthetic process GO:0016053 86 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
fatty acid metabolic process GO:0006631 121 0.011
striated muscle cell development GO:0055002 125 0.011
tube formation GO:0035148 140 0.011
renal system development GO:0072001 225 0.011
lung development GO:0030324 164 0.011
cytoplasmic transport GO:0016482 234 0.011
Human
embryonic organ morphogenesis GO:0048562 276 0.011
muscle contraction GO:0006936 101 0.011
nuclear division GO:0000280 158 0.011
carbohydrate homeostasis GO:0033500 128 0.011
response to insulin GO:0032868 100 0.011
glycoprotein metabolic process GO:0009100 116 0.011
wnt signaling pathway GO:0016055 188 0.011
germ cell development GO:0007281 185 0.011
anion transmembrane transport GO:0098656 71 0.011
anatomical structure homeostasis GO:0060249 145 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
synapse organization GO:0050808 125 0.011
positive regulation of organelle organization GO:0010638 128 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of protein complex assembly GO:0043254 83 0.010
leukocyte proliferation GO:0070661 172 0.010
regulation of asymmetric cell division GO:0009786 4 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
response to radiation GO:0009314 165 0.010
sequestering of calcium ion GO:0051208 18 0.010
methylation GO:0032259 134 0.010
memory GO:0007613 58 0.010
fat cell differentiation GO:0045444 160 0.010
positive regulation of proteolysis GO:0045862 85 0.010
carboxylic acid transport GO:0046942 100 0.010
lateral inhibition GO:0046331 1 0.010
apical constriction GO:0003383 4 0.010
regulation of metal ion transport GO:0010959 106 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.010
positive regulation of cell activation GO:0050867 158 0.010
regulation of defense response GO:0031347 233 0.010
leukocyte migration GO:0050900 124 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010

Sgsm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.041
neuromuscular disease DOID:440 0 0.013
neuropathy DOID:870 0 0.013
charcot marie tooth disease DOID:10595 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012