Mus musculus

39 known processes

Col5a2

collagen, type V, alpha 2

(Aliases: D230017N05,1110014L14Rik)

Col5a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteoglycan metabolic process GO:0006029 38 0.954
Mouse
extracellular matrix organization GO:0030198 147 0.952
cellular response to growth factor stimulus GO:0071363 197 0.943
Mouse
extracellular structure organization GO:0043062 148 0.924
aorta smooth muscle tissue morphogenesis GO:0060414 2 0.882
Mouse
connective tissue development GO:0061448 179 0.832
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.826
response to amino acid GO:0043200 37 0.820
chondrocyte differentiation GO:0002062 72 0.816
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.814
bone trabecula morphogenesis GO:0061430 12 0.800
Mouse
cartilage condensation GO:0001502 18 0.787
Mouse
protein heterotrimerization GO:0070208 8 0.745
Mouse
positive regulation of cell substrate adhesion GO:0010811 47 0.738
fibril organization GO:0097435 2 0.718
skeletal system development GO:0001501 356 0.714
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.705
Mouse
bone development GO:0060348 120 0.634
Mouse
response to growth factor GO:0070848 198 0.625
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.603
Mouse
extracellular fibril organization GO:0043206 2 0.587
signal transduction in absence of ligand GO:0038034 55 0.584
Mouse
protein heterooligomerization GO:0051291 14 0.556
Mouse
bone trabecula formation GO:0060346 9 0.556
Mouse
limb bud formation GO:0060174 10 0.551
Mouse
ossification GO:0001503 216 0.541
Mouse Rat
extrinsic apoptotic signaling pathway GO:0097191 126 0.539
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.515
Mouse
negative regulation of neuron migration GO:2001223 6 0.481
Mouse
negative regulation of cell substrate adhesion GO:0010812 16 0.474
Mouse
cell substrate adhesion GO:0031589 130 0.469
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.447
Mouse
rho protein signal transduction GO:0007266 32 0.445
Mouse
cerebral cortex development GO:0021987 86 0.429
Mouse
negative regulation of cell migration GO:0030336 59 0.412
Mouse
trabecula morphogenesis GO:0061383 40 0.410
Mouse
response to transforming growth factor beta GO:0071559 88 0.395
collagen fibril organization GO:0030199 32 0.395
notochord development GO:0030903 20 0.389
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.383
trabecula formation GO:0060343 24 0.380
Mouse
negative regulation of cell motility GO:2000146 61 0.376
Mouse
negative regulation of blood vessel morphogenesis GO:2000181 25 0.376
protein trimerization GO:0070206 13 0.368
Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.365
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.364
Mouse
cartilage development GO:0051216 140 0.356
Mouse
regulation of cell migration GO:0030334 219 0.353
Mouse
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.351
Mouse
cellular response to acid chemical GO:0071229 68 0.346
negative regulation of angiogenesis GO:0016525 25 0.338
anatomical structure homeostasis GO:0060249 145 0.333
Mouse
cell matrix adhesion GO:0007160 68 0.327
Mouse
tissue homeostasis GO:0001894 115 0.319
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.312
Mouse
negative regulation of cell adhesion GO:0007162 45 0.296
Mouse
sensory perception of sound GO:0007605 97 0.284
Mouse
forebrain development GO:0030900 302 0.283
Mouse
face morphogenesis GO:0060325 29 0.276
Mouse
ear morphogenesis GO:0042471 118 0.272
Mouse
blood vessel morphogenesis GO:0048514 285 0.271
Mouse
inner ear morphogenesis GO:0042472 101 0.264
Mouse
sensory organ morphogenesis GO:0090596 242 0.263
Human Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.256
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.252
cardiac ventricle morphogenesis GO:0003208 50 0.252
Mouse
replacement ossification GO:0036075 26 0.250
Mouse
cell adhesion GO:0007155 329 0.250
Mouse
negative regulation of tooth mineralization GO:0070171 1 0.244
aorta development GO:0035904 23 0.235
Mouse
pallium development GO:0021543 120 0.225
Mouse
otic vesicle development GO:0071599 14 0.223
Mouse
endochondral bone morphogenesis GO:0060350 50 0.219
Mouse
negative regulation of cell development GO:0010721 169 0.218
Mouse
response to bmp GO:0071772 14 0.217
Mouse
muscle tissue morphogenesis GO:0060415 53 0.215
Mouse
cardiac ventricle development GO:0003231 83 0.214
Mouse
negative regulation of vasculature development GO:1901343 26 0.213
protein oligomerization GO:0051259 67 0.209
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.207
Mouse
regulation of cell motility GO:2000145 236 0.207
Mouse
limb morphogenesis GO:0035108 149 0.205
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.204
Mouse
neuron migration GO:0001764 122 0.199
Mouse
telencephalon development GO:0021537 186 0.195
Mouse
response to organonitrogen compound GO:0010243 246 0.185
heart morphogenesis GO:0003007 178 0.183
Mouse
regulation of tooth mineralization GO:0070170 2 0.171
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.171
embryonic skeletal system development GO:0048706 120 0.168
Mouse
wound healing GO:0042060 157 0.159
response to acid chemical GO:0001101 111 0.157
skeletal system morphogenesis GO:0048705 203 0.151
Mouse
artery development GO:0060840 53 0.147
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.140
Mouse
muscle tissue development GO:0060537 308 0.140
Mouse
head morphogenesis GO:0060323 34 0.132
Mouse
lung development GO:0030324 164 0.131
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.128
Mouse
regulation of neuron migration GO:2001222 22 0.128
Mouse
tendon development GO:0035989 6 0.125
Mouse
digestive system development GO:0055123 200 0.121
Human Mouse
appendage development GO:0048736 166 0.119
Mouse
single organism cell adhesion GO:0098602 156 0.113
appendage morphogenesis GO:0035107 149 0.113
Mouse
regulation of cell adhesion GO:0030155 154 0.113
Mouse
aorta morphogenesis GO:0035909 22 0.111
Mouse
positive regulation of rho protein signal transduction GO:0035025 7 0.111
Mouse
multicellular organismal homeostasis GO:0048871 164 0.110
Mouse
peptide cross linking GO:0018149 10 0.098
cellular response to bmp stimulus GO:0071773 14 0.097
Mouse
digestive tract development GO:0048565 190 0.095
Human Mouse
cardiac chamber morphogenesis GO:0003206 93 0.093
Mouse
embryonic organ morphogenesis GO:0048562 276 0.091
Mouse
sensory perception of mechanical stimulus GO:0050954 107 0.091
Mouse
ras protein signal transduction GO:0007265 77 0.085
Mouse
cellular response to external stimulus GO:0071496 88 0.085
Mouse
response to catecholamine GO:0071869 4 0.078
protein hydroxylation GO:0018126 4 0.073
astrocyte cell migration GO:0043615 3 0.073
retinal blood vessel morphogenesis GO:0061304 3 0.072
ventricular cardiac muscle tissue development GO:0003229 38 0.072
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.067
regulation of sphingolipid biosynthetic process GO:0090153 1 0.067
negative regulation of epithelial cell proliferation GO:0050680 64 0.066
direct ossification GO:0036072 5 0.065
Mouse
negative regulation of odontogenesis GO:0042483 3 0.063
sensory perception GO:0007600 245 0.062
Mouse
negative regulation of cell proliferation GO:0008285 296 0.061
response to organic cyclic compound GO:0014070 198 0.061
regulation of angiogenesis GO:0045765 81 0.055
angiogenesis GO:0001525 201 0.054
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.053
positive regulation of ras protein signal transduction GO:0046579 13 0.050
Mouse
bone morphogenesis GO:0060349 78 0.049
Mouse
mesenchymal epithelial cell signaling involved in prostate gland development GO:0060739 1 0.049
apoptotic signaling pathway GO:0097190 306 0.048
Mouse
regulation of proteolysis GO:0030162 164 0.046
respiratory tube development GO:0030323 167 0.045
smooth muscle tissue development GO:0048745 22 0.045
Mouse
intussusceptive angiogenesis GO:0002041 2 0.045
limb development GO:0060173 166 0.044
Mouse
regulation of transmission of nerve impulse GO:0051969 1 0.043
negative regulation of nervous system development GO:0051961 156 0.042
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.042
Mouse
positive regulation of cell motility GO:2000147 116 0.040
regulation of chondrocyte differentiation GO:0032330 33 0.040
regulation of cellular response to growth factor stimulus GO:0090287 82 0.040
positive regulation of cell migration GO:0030335 109 0.040
regulation of ceramide biosynthetic process GO:2000303 1 0.039
chondrocyte development GO:0002063 24 0.039
Mouse
endothelial cell migration GO:0043542 44 0.038
neuromuscular process GO:0050905 99 0.037
renal system development GO:0072001 225 0.036
epithelial cell proliferation GO:0050673 174 0.036
response to thyroid hormone GO:0097066 2 0.036
striated muscle tissue development GO:0014706 293 0.036
Mouse
protein processing GO:0016485 163 0.035
ameboidal type cell migration GO:0001667 128 0.035
jnk cascade GO:0007254 72 0.034
growth plate cartilage development GO:0003417 14 0.034
negative regulation of protein activation cascade GO:2000258 3 0.034
glycoprotein metabolic process GO:0009100 116 0.034
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.034
hair follicle morphogenesis GO:0031069 29 0.034
response to radiation GO:0009314 165 0.033
cellular response to mechanical stimulus GO:0071260 7 0.033
Mouse
synaptic transmission cholinergic GO:0007271 7 0.032
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.031
regulation of fibrinolysis GO:0051917 1 0.031
negative regulation of ossification GO:0030279 49 0.029
synapse organization GO:0050808 125 0.029
regulation of body fluid levels GO:0050878 162 0.029
engulfment of apoptotic cell GO:0043652 3 0.027
response to epidermal growth factor GO:0070849 4 0.027
nephron development GO:0072006 109 0.026
positive regulation of proteolysis GO:0045862 85 0.026
sphingolipid biosynthetic process GO:0030148 26 0.025
response to oxidative stress GO:0006979 123 0.025
integrin mediated signaling pathway GO:0007229 27 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
oviduct development GO:0060066 3 0.025
regulation of ras protein signal transduction GO:0046578 114 0.024
Mouse
protein maturation GO:0051604 176 0.024
positive regulation of response to wounding GO:1903036 66 0.024
regulation of translation GO:0006417 71 0.024
cell adhesion mediated by integrin GO:0033627 18 0.024
regulation of hemostasis GO:1900046 28 0.024
regulation of embryonic development GO:0045995 71 0.024
Human
neuromuscular process controlling balance GO:0050885 59 0.023
mesenchymal cell differentiation GO:0048762 107 0.023
cellular response to vitamin GO:0071295 2 0.023
negative regulation of complement activation GO:0045916 3 0.023
elastic fiber assembly GO:0048251 4 0.023
cell aggregation GO:0098743 18 0.022
Mouse
response to inorganic substance GO:0010035 96 0.022
oxidation reduction process GO:0055114 342 0.022
peptidyl amino acid modification GO:0018193 336 0.022
fibrinolysis GO:0042730 3 0.022
peripheral nervous system axon regeneration GO:0014012 2 0.022
regulation of removal of superoxide radicals GO:2000121 4 0.022
response to peptide hormone GO:0043434 127 0.022
response to extracellular stimulus GO:0009991 127 0.022
cellular response to lipid GO:0071396 145 0.021
sulfur compound metabolic process GO:0006790 100 0.021
regulation of vasculature development GO:1901342 88 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
response to monosaccharide GO:0034284 67 0.020
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan GO:0019800 8 0.020
synaptic transmission glutamatergic GO:0035249 36 0.020
protein catabolic process GO:0030163 221 0.020
skeletal muscle organ development GO:0060538 163 0.020
substrate adhesion dependent cell spreading GO:0034446 30 0.020
anatomical structure maturation GO:0071695 49 0.020
positive regulation of cell adhesion GO:0045785 80 0.020
regulation of ossification GO:0030278 112 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
endodermal cell differentiation GO:0035987 14 0.019
Human
developmental cell growth GO:0048588 84 0.018
endomembrane system organization GO:0010256 147 0.018
cellular response to nitric oxide GO:0071732 4 0.018
regulation of biomineral tissue development GO:0070167 33 0.018
negative regulation of embryonic development GO:0045992 22 0.018
Human
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.017
regulation of tissue remodeling GO:0034103 38 0.017
chondroblast differentiation GO:0060591 2 0.017
cardiac muscle tissue development GO:0048738 130 0.017
Mouse
synaptic transmission GO:0007268 329 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
aldosterone metabolic process GO:0032341 2 0.017
tissue migration GO:0090130 68 0.017
lateral line system development GO:0048925 1 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
cell recognition GO:0008037 83 0.016
epithelial to mesenchymal transition GO:0001837 47 0.016
eosinophil migration GO:0072677 3 0.016
positive regulation of neuron projection regeneration GO:0070572 2 0.016
sequestering of bmp in extracellular matrix GO:0035582 3 0.016
biomineral tissue development GO:0031214 64 0.016
regulation of rho protein signal transduction GO:0035023 71 0.016
Mouse
sensory system development GO:0048880 3 0.016
forebrain cell migration GO:0021885 58 0.016
positive regulation of cell death GO:0010942 224 0.016
telencephalon cell migration GO:0022029 55 0.016
stem cell development GO:0048864 219 0.015
peptidyl proline hydroxylation GO:0019511 3 0.015
positive regulation of neuron projection development GO:0010976 79 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
detection of external stimulus GO:0009581 61 0.015
positive regulation of bone remodeling GO:0046852 13 0.015
endoderm formation GO:0001706 20 0.015
Human
response to oxygen radical GO:0000305 16 0.015
translation GO:0006412 93 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
hair cycle GO:0042633 90 0.015
response to metal ion GO:0010038 47 0.015
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.014
cellular response to superoxide GO:0071451 14 0.014
negative regulation of fibrinolysis GO:0051918 1 0.014
regulation of epithelial cell migration GO:0010632 35 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
cardiac muscle cell development GO:0055013 39 0.014
ear development GO:0043583 200 0.014
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.014
membrane lipid biosynthetic process GO:0046467 32 0.014
hair follicle development GO:0001942 85 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
cellular ketone metabolic process GO:0042180 84 0.013
negative regulation of macrophage chemotaxis GO:0010760 1 0.013
response to monoamine GO:0071867 4 0.013
ceramide biosynthetic process GO:0046513 20 0.013
negative regulation of molecular function GO:0044092 258 0.013
regulation of endodermal cell differentiation GO:1903224 2 0.013
Human
cardiac chamber development GO:0003205 108 0.013
Mouse
negative regulation of endothelial cell proliferation GO:0001937 8 0.013
protein autoprocessing GO:0016540 2 0.013
bone resorption GO:0045453 38 0.013
epidermis development GO:0008544 187 0.012
regulation of cell size GO:0008361 72 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.012
Mouse
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.012
carbohydrate homeostasis GO:0033500 128 0.012
cell growth involved in cardiac muscle cell development GO:0061049 3 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
protein targeting GO:0006605 143 0.012
astrocyte fate commitment GO:0060018 4 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
plasma membrane organization GO:0007009 90 0.012
regulation of map kinase activity GO:0043405 120 0.012
sensory perception of light stimulus GO:0050953 54 0.012
regulation of phospholipase a2 activity GO:0032429 3 0.012
regulation of blood coagulation GO:0030193 28 0.012
covalent chromatin modification GO:0016569 163 0.011
plasma membrane long chain fatty acid transport GO:0015911 1 0.011
cellular response to epidermal growth factor stimulus GO:0071364 4 0.011
notochord cell differentiation GO:0060034 1 0.011
molting cycle GO:0042303 90 0.011
heart valve development GO:0003170 23 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
camera type eye development GO:0043010 266 0.011
response to pain GO:0048265 26 0.011
regulation of neuron projection development GO:0010975 169 0.011
cardiac cell development GO:0055006 41 0.011
metanephric glomerular basement membrane development GO:0072274 1 0.011
cellular lipid metabolic process GO:0044255 323 0.011
development of primary sexual characteristics GO:0045137 143 0.011
neuron neuron synaptic transmission GO:0007270 69 0.011
cell growth GO:0016049 130 0.011
positive regulation of growth GO:0045927 104 0.011
endoderm development GO:0007492 45 0.011
Human
positive regulation of programmed cell death GO:0043068 218 0.010
negative regulation of plasminogen activation GO:0010757 2 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
urogenital system development GO:0001655 261 0.010
regulation of cellular response to stress GO:0080135 159 0.010
regulation of neurological system process GO:0031644 22 0.010
response to fibroblast growth factor GO:0071774 47 0.010
photoreceptor cell development GO:0042461 40 0.010
negative regulation of hydrolase activity GO:0051346 71 0.010

Col5a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.958
Human
musculoskeletal system disease DOID:17 0 0.958
Human
connective tissue disease DOID:65 0 0.958
Human
myopathy DOID:423 0 0.535
muscular disease DOID:0080000 0 0.535
muscle tissue disease DOID:66 0 0.535
collagen disease DOID:854 0 0.432
Human
ehlers danlos syndrome DOID:13359 0 0.432
Human
congenital muscular dystrophy DOID:0050557 0 0.377
muscular dystrophy DOID:9884 0 0.377
osteochondrodysplasia DOID:2256 0 0.153
osteogenesis imperfecta DOID:12347 0 0.153
bone development disease DOID:0080006 0 0.153
bone disease DOID:0080001 0 0.153
bone remodeling disease DOID:0080005 0 0.114
osteoporosis DOID:11476 0 0.054
bone resorption disease DOID:0080011 0 0.054
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.014
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
nervous system disease DOID:863 0 0.014
eye disease DOID:5614 0 0.014
glaucoma DOID:1686 0 0.011