|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.925
|
Human |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.752
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.656
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.617
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.546
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.459
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.443
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.406
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.400
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.388
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.363
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.326
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.318
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.316
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.304
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.303
|
Worm |
|
|
response to radiation
|
GO:0009314 |
165 |
0.300
|
Human Worm |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.277
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.262
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.251
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.240
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.231
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.229
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.225
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.224
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.218
|
Human Worm |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.212
|
Human Worm |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.206
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.204
|
Human Worm |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.201
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.198
|
Human Worm |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.196
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.195
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.189
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.187
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.176
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.175
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.173
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.163
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.156
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.156
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.155
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.153
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.153
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.153
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
4 |
0.152
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.151
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.150
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.148
|
Human Worm |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.147
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.146
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.145
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.145
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.145
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.143
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.143
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.143
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.140
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.138
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.137
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.137
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.129
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.128
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.126
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.126
|
|
|
|
spindle assembly involved in mitosis
|
GO:0090307 |
4 |
0.125
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.123
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.123
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.123
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.122
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.122
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.121
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.120
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.119
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.116
|
|
|
|
telomere maintenance via telomerase
|
GO:0007004 |
1 |
0.115
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.115
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.112
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.112
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.112
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.111
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.109
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.109
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.107
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.106
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.106
|
Human Worm |
|
|
organelle fission
|
GO:0048285 |
170 |
0.105
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.104
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.103
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.102
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.102
|
Human |
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.101
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.100
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.098
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.098
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.096
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.094
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.093
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.093
|
Human Worm |
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.091
|
|
|
|
telomere capping
|
GO:0016233 |
4 |
0.091
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.091
|
Human Worm |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.089
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.089
|
|
|
|
rna dependent dna replication
|
GO:0006278 |
3 |
0.088
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.087
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.087
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.087
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.086
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.085
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.085
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.084
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.084
|
|
|
|
telomere maintenance
|
GO:0000723 |
19 |
0.083
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.083
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.082
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.082
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.082
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.082
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.081
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.081
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.080
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.080
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.080
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.080
|
Human Worm |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.079
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.079
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.079
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.079
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.078
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.077
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.077
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.077
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.076
|
Human Worm |
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
15 |
0.076
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.076
|
|
|
|
cilium assembly
|
GO:0042384 |
81 |
0.076
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.075
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.074
|
Worm |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.074
|
Human Worm |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.074
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.073
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.072
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.072
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.072
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.072
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.071
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.070
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.070
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.070
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.070
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.070
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.070
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.069
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.069
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.068
|
Human Worm |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.068
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.068
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.068
|
Human Worm |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.068
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.068
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.067
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.067
|
Human Worm |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.067
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.066
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.066
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.066
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.065
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.065
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.065
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.065
|
Human Worm |
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.064
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.063
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.063
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.061
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.061
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.060
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.060
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.059
|
Human Worm |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.059
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.059
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.059
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.059
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.059
|
Human |
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.059
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.058
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.057
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.057
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
3 |
0.056
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.056
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.056
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.056
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.056
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.055
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.055
|
Human Worm |
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.055
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.054
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.054
|
Human |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.053
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.053
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.053
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.053
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.052
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.052
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.052
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.051
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.051
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.051
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.051
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.050
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.050
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.050
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.049
|
Human Worm |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.049
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.049
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.049
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.049
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.049
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.048
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.048
|
Human Worm |
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.048
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.048
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.048
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.048
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.047
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.047
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.047
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.047
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.047
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.047
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.047
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.046
|
|
|
|
positive regulation of interleukin 1 alpha production
|
GO:0032730 |
4 |
0.046
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.046
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.046
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.045
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.045
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.045
|
Human Worm |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.044
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.044
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.044
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.044
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.044
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.043
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.043
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.043
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.043
|
Worm |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.043
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.043
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.042
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.042
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.042
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.042
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.042
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.042
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.042
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.042
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.042
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.042
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.042
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.042
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.042
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.041
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.041
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.041
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.041
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.041
|
|
|
|
double strand break repair
|
GO:0006302 |
48 |
0.041
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.041
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.041
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.040
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.040
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.040
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.040
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.039
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.039
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.039
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.039
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.039
|
Human Worm |
|
|
protection from non homologous end joining at telomere
|
GO:0031848 |
4 |
0.039
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.039
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.038
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.038
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.038
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.038
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.038
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.038
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.038
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.037
|
Human Worm |
|
|
centrosome organization
|
GO:0051297 |
26 |
0.037
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.037
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.037
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.037
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.037
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.036
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.036
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.036
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.036
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.036
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.036
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.035
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.035
|
Human Worm |
|
|
hepatocyte apoptotic process
|
GO:0097284 |
11 |
0.035
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.035
|
|
|
|
centrosome cycle
|
GO:0007098 |
23 |
0.035
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.035
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.035
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.035
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
12 |
0.035
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.035
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.034
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.034
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.034
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.034
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.034
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.034
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.033
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.033
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.033
|
Human Worm |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.033
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.033
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.032
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.032
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.032
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.032
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.032
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
13 |
0.032
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.031
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.031
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.031
|
Human Worm |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.031
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.031
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.031
|
Human Worm |
|
|
tube formation
|
GO:0035148 |
140 |
0.031
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.031
|
Human Worm |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.031
|
|
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
6 |
0.031
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.031
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.030
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.030
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.030
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.030
|
|
|
|
amp metabolic process
|
GO:0046033 |
4 |
0.030
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.030
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.030
|
|
|
|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
2 |
0.030
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.030
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.030
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.030
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.030
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.030
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.030
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.030
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.030
|
|
|
|
response to x ray
|
GO:0010165 |
11 |
0.030
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.030
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.030
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.030
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.029
|
Human Worm |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.029
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.029
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.029
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.029
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.029
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.029
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.029
|
|
|
|
dna catabolic process
|
GO:0006308 |
19 |
0.029
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.029
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.028
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.028
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.028
|
Human Worm |
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.028
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.028
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.028
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.028
|
Human Worm |
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.028
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.028
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.028
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.028
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.028
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.028
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.028
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.028
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.028
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
3 |
0.027
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.027
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.027
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.027
|
|
|
|
telomere maintenance in response to dna damage
|
GO:0043247 |
4 |
0.027
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.027
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
3 |
0.027
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.027
|
Human Worm |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.027
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.027
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.027
|
|
|
|
dna endoreduplication
|
GO:0042023 |
4 |
0.027
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.027
|
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.026
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.026
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.026
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.026
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.026
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.026
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.026
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.026
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.026
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.026
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.026
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.025
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.025
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.025
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.025
|
Human Worm |
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.025
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.025
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.025
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.025
|
Human Worm |
|
|
protein polymerization
|
GO:0051258 |
57 |
0.025
|
|
|
|
negative regulation of release of cytochrome c from mitochondria
|
GO:0090201 |
6 |
0.025
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.025
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.025
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.025
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.025
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.024
|
|
|
|
lens fiber cell apoptotic process
|
GO:1990086 |
4 |
0.024
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.024
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.024
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.024
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.024
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.024
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.024
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.024
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
20 |
0.024
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.024
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.024
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.024
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.024
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.024
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.024
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.024
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.024
|
Human Worm |
|
|
negative regulation of osteoblast proliferation
|
GO:0033689 |
4 |
0.024
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.024
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.024
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.024
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.024
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.024
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.024
|
Human Worm |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.023
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.023
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.023
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.023
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.023
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.023
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.023
|
Human Worm |
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.023
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.023
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
58 |
0.023
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.023
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
25 |
0.023
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.022
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.022
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.022
|
Human Worm |
|
|
regulation of interleukin 1 alpha production
|
GO:0032650 |
4 |
0.022
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.022
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.022
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
3 |
0.022
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.022
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.022
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.022
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.022
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.022
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.022
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.022
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.022
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.022
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.022
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.022
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.022
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.022
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.021
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.021
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.021
|
|
