Mus musculus

0 known processes

Nsmaf

neutral sphingomyelinase (N-SMase) activation associated factor

(Aliases: AA959567,Fan,C630007J05)

Nsmaf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound catabolic process GO:1901361 295 0.194
cellular ketone metabolic process GO:0042180 84 0.084
apoptotic signaling pathway GO:0097190 306 0.082
nucleoside phosphate metabolic process GO:0006753 338 0.076
macromolecule catabolic process GO:0009057 281 0.071
protein modification by small protein conjugation or removal GO:0070647 207 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.064
cellular amino acid metabolic process GO:0006520 103 0.064
positive regulation of apoptotic process GO:0043065 217 0.062
ribose phosphate metabolic process GO:0019693 291 0.061
purine nucleotide catabolic process GO:0006195 211 0.058
ribonucleoside catabolic process GO:0042454 206 0.057
purine containing compound metabolic process GO:0072521 311 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.056
regulation of cell cycle GO:0051726 281 0.053
nucleotide metabolic process GO:0009117 332 0.052
cellular amine metabolic process GO:0044106 44 0.052
nucleoside catabolic process GO:0009164 206 0.051
peptidyl amino acid modification GO:0018193 336 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
aromatic compound catabolic process GO:0019439 286 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.048
ribonucleoside metabolic process GO:0009119 245 0.048
heterocycle catabolic process GO:0046700 280 0.048
glycosyl compound metabolic process GO:1901657 246 0.048
amine metabolic process GO:0009308 45 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
developmental maturation GO:0021700 193 0.047
purine ribonucleoside metabolic process GO:0046128 241 0.047
purine nucleotide metabolic process GO:0006163 302 0.046
organelle fission GO:0048285 170 0.046
negative regulation of protein metabolic process GO:0051248 282 0.046
positive regulation of programmed cell death GO:0043068 218 0.046
ribonucleotide metabolic process GO:0009259 291 0.046
carbohydrate derivative catabolic process GO:1901136 231 0.045
small gtpase mediated signal transduction GO:0007264 97 0.043
purine nucleoside metabolic process GO:0042278 241 0.043
cellular macromolecule catabolic process GO:0044265 206 0.042
nuclear division GO:0000280 158 0.041
cellular response to dna damage stimulus GO:0006974 207 0.040
negative regulation of molecular function GO:0044092 258 0.040
synaptic transmission GO:0007268 329 0.040
protein catabolic process GO:0030163 221 0.039
protein modification by small protein conjugation GO:0032446 187 0.039
nucleoside metabolic process GO:0009116 246 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.038
positive regulation of cell death GO:0010942 224 0.038
regulation of hydrolase activity GO:0051336 246 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
nucleotide catabolic process GO:0009166 217 0.037
response to organonitrogen compound GO:0010243 246 0.037
microtubule based process GO:0007017 236 0.036
organophosphate catabolic process GO:0046434 232 0.035
protein maturation GO:0051604 176 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
ribonucleotide catabolic process GO:0009261 208 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
protein ubiquitination GO:0016567 171 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
regulation of protein localization GO:0032880 231 0.033
carbohydrate metabolic process GO:0005975 230 0.033
regulation of organelle organization GO:0033043 289 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
transmembrane transport GO:0055085 412 0.032
meiotic nuclear division GO:0007126 115 0.032
cation transmembrane transport GO:0098655 266 0.031
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
microtubule nucleation GO:0007020 2 0.031
positive regulation of hydrolase activity GO:0051345 148 0.031
protein processing GO:0016485 163 0.030
cation transport GO:0006812 399 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
ras protein signal transduction GO:0007265 77 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
rho protein signal transduction GO:0007266 32 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
cellular lipid metabolic process GO:0044255 323 0.028
glucose homeostasis GO:0042593 128 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
meiotic cell cycle GO:0051321 122 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
maintenance of location GO:0051235 89 0.026
ribonucleoside monophosphate metabolic process GO:0009161 80 0.026
regulation of cell cycle process GO:0010564 160 0.026
purine containing compound catabolic process GO:0072523 213 0.026
organelle localization GO:0051640 179 0.026
mitotic cell cycle GO:0000278 195 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.025
oxidation reduction process GO:0055114 342 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
organelle assembly GO:0070925 177 0.025
cytokine production GO:0001816 319 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.025
neuron apoptotic process GO:0051402 142 0.025
regulation of membrane potential GO:0042391 192 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
regulation of cytokine production GO:0001817 266 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
cellular response to organonitrogen compound GO:0071417 145 0.023
guanosine containing compound catabolic process GO:1901069 144 0.023
response to lipopolysaccharide GO:0032496 128 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
immune effector process GO:0002252 321 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
response to peptide hormone GO:0043434 127 0.022
dephosphorylation GO:0016311 129 0.022
cellular response to hormone stimulus GO:0032870 150 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
lipid localization GO:0010876 126 0.021
negative regulation of cell cycle GO:0045786 123 0.021
dna metabolic process GO:0006259 303 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
male gamete generation GO:0048232 285 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
cellular homeostasis GO:0019725 240 0.020
carbohydrate homeostasis GO:0033500 128 0.019
striated muscle tissue development GO:0014706 293 0.019
regulation of cellular response to stress GO:0080135 159 0.019
cell type specific apoptotic process GO:0097285 268 0.019
establishment of vesicle localization GO:0051650 81 0.019
membrane organization GO:0061024 245 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
gonad development GO:0008406 141 0.019
locomotory behavior GO:0007626 195 0.019
cell adhesion GO:0007155 329 0.019
action potential GO:0001508 78 0.019
mrna metabolic process GO:0016071 84 0.019
anatomical structure homeostasis GO:0060249 145 0.019
ion transmembrane transport GO:0034220 361 0.018
muscle cell differentiation GO:0042692 261 0.018
leukocyte differentiation GO:0002521 342 0.018
homeostasis of number of cells GO:0048872 210 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.018
regulation of transferase activity GO:0051338 263 0.018
regulation of protein processing GO:0070613 96 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
cellular protein complex assembly GO:0043623 116 0.018
engulfment of apoptotic cell GO:0043652 3 0.017
chemotaxis GO:0006935 247 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
regulation of homeostatic process GO:0032844 182 0.017
mapk cascade GO:0000165 281 0.017
negative regulation of protein modification process GO:0031400 163 0.017
cytoplasmic transport GO:0016482 234 0.017
atp metabolic process GO:0046034 75 0.017
multicellular organism growth GO:0035264 161 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
response to insulin GO:0032868 100 0.017
regulation of proteolysis GO:0030162 164 0.017
spermatogenesis GO:0007283 284 0.017
regulation of hormone levels GO:0010817 211 0.017
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of protein maturation GO:1903317 96 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
positive regulation of protein modification process GO:0031401 299 0.016
gtp catabolic process GO:0006184 143 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
regulation of secretion GO:0051046 274 0.016
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
response to peptide GO:1901652 136 0.016
mitochondrion distribution GO:0048311 4 0.016
activation of immune response GO:0002253 138 0.016
circadian rhythm GO:0007623 114 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
peptidyl serine modification GO:0018209 83 0.016
regulation of peptidase activity GO:0052547 96 0.016
regulation of engulfment of apoptotic cell GO:1901074 2 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
regulation of cell cycle phase transition GO:1901987 77 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
protein polymerization GO:0051258 57 0.015
nitrogen compound transport GO:0071705 271 0.015
cellular chemical homeostasis GO:0055082 215 0.015
divalent metal ion transport GO:0070838 172 0.015
ossification GO:0001503 216 0.015
translation GO:0006412 93 0.015
regulation of cell activation GO:0050865 289 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
regulation of defense response GO:0031347 233 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
digestive system development GO:0055123 200 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
divalent inorganic cation transport GO:0072511 178 0.015
endocytosis GO:0006897 168 0.015
microtubule based movement GO:0007018 84 0.015
stem cell differentiation GO:0048863 268 0.015
leukocyte mediated immunity GO:0002443 174 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
adult behavior GO:0030534 135 0.014
multicellular organismal signaling GO:0035637 91 0.014
cell cycle checkpoint GO:0000075 47 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
digestive tract development GO:0048565 190 0.014
t cell activation GO:0042110 289 0.014
protein localization to organelle GO:0033365 185 0.014
neuronal action potential GO:0019228 54 0.014
blood circulation GO:0008015 195 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
intracellular protein transport GO:0006886 204 0.014
sensory perception GO:0007600 245 0.014
cellular response to peptide GO:1901653 92 0.014
regulation of ras gtpase activity GO:0032318 88 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
positive regulation of defense response GO:0031349 124 0.014
regulation of protein transport GO:0051223 163 0.013
mitotic cell cycle process GO:1903047 159 0.013
glycerolipid metabolic process GO:0046486 122 0.013
cell division GO:0051301 120 0.013
cellular response to lipid GO:0071396 145 0.013
regulation of kinase activity GO:0043549 249 0.013
germ cell development GO:0007281 185 0.013
skeletal muscle organ development GO:0060538 163 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of secretion by cell GO:1903530 249 0.013
phospholipid metabolic process GO:0006644 87 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
inositol phosphate catabolic process GO:0071545 4 0.013
compound eye development GO:0048749 1 0.013
positive regulation of cell development GO:0010720 237 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
skeletal muscle cell differentiation GO:0035914 66 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
chromatin modification GO:0016568 187 0.013
transmission of nerve impulse GO:0019226 76 0.013
muscle tissue development GO:0060537 308 0.013
regulation of mapk cascade GO:0043408 248 0.013
protein oligomerization GO:0051259 67 0.012
histone modification GO:0016570 159 0.012
muscle system process GO:0003012 141 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
lymphocyte differentiation GO:0030098 242 0.012
t cell differentiation in thymus GO:0033077 77 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
learning or memory GO:0007611 148 0.012
cellular protein catabolic process GO:0044257 155 0.012
mitochondrion organization GO:0007005 134 0.012
positive regulation of ras gtpase activity GO:0032320 65 0.012
positive regulation of organelle organization GO:0010638 128 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
dna repair GO:0006281 107 0.012
methylation GO:0032259 134 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
rna splicing GO:0008380 54 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
cellular ion homeostasis GO:0006873 165 0.012
response to light stimulus GO:0009416 135 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
urogenital system development GO:0001655 261 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
positive regulation of cell cycle GO:0045787 92 0.012
stem cell development GO:0048864 219 0.012
defense response to other organism GO:0098542 197 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
humoral immune response GO:0006959 57 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
multi multicellular organism process GO:0044706 109 0.012
gene silencing GO:0016458 38 0.012
response to oxygen levels GO:0070482 62 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
regulation of response to wounding GO:1903034 189 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
negative regulation of protein processing GO:0010955 79 0.012
regulation of transmembrane transport GO:0034762 128 0.011
actin cytoskeleton organization GO:0030036 220 0.011
cell maturation GO:0048469 127 0.011
rhythmic process GO:0048511 174 0.011
protein localization to membrane GO:0072657 108 0.011
respiratory system development GO:0060541 190 0.011
calcium ion homeostasis GO:0055074 127 0.011
regulation of system process GO:0044057 200 0.011
mitotic cell cycle checkpoint GO:0007093 31 0.011
positive regulation of cytokine production GO:0001819 174 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
lipid biosynthetic process GO:0008610 179 0.011
neuron death GO:0070997 154 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
epithelial cell proliferation GO:0050673 174 0.011
leukocyte proliferation GO:0070661 172 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of intracellular transport GO:0032386 159 0.011
meiotic cell cycle process GO:1903046 77 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
establishment of organelle localization GO:0051656 122 0.011
digestive tract morphogenesis GO:0048546 147 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
nuclear transport GO:0051169 139 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
rna processing GO:0006396 105 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
forebrain development GO:0030900 302 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
cation homeostasis GO:0055080 212 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
adult locomotory behavior GO:0008344 91 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
dna integrity checkpoint GO:0031570 28 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
response to growth factor GO:0070848 198 0.010
protein autophosphorylation GO:0046777 61 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
wnt signaling pathway GO:0016055 188 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
myeloid cell differentiation GO:0030099 233 0.010
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.010
positive regulation of proteolysis GO:0045862 85 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
protein localization to chromatin GO:0071168 3 0.010
regulation of ion transport GO:0043269 215 0.010
purine nucleoside monophosphate catabolic process GO:0009128 58 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
vesicle localization GO:0051648 86 0.010
response to oxidative stress GO:0006979 123 0.010
neuron projection guidance GO:0097485 141 0.010

Nsmaf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010