Mus musculus

85 known processes

Stag2

stromal antigen 2

(Aliases: SA-2,B230112I07Rik,9230105L23Rik,SAP2)

Stag2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle localization GO:0051640 179 0.580
cell junction organization GO:0034330 77 0.567
positive regulation of gtpase activity GO:0043547 85 0.557
regulation of cell cycle process GO:0010564 160 0.553
Human
purine ribonucleoside catabolic process GO:0046130 205 0.493
organophosphate catabolic process GO:0046434 232 0.455
guanosine containing compound catabolic process GO:1901069 144 0.442
mitotic sister chromatid cohesion GO:0007064 1 0.440
guanosine containing compound metabolic process GO:1901068 144 0.436
purine ribonucleoside metabolic process GO:0046128 241 0.316
nucleoside catabolic process GO:0009164 206 0.311
ras protein signal transduction GO:0007265 77 0.299
positive regulation of gtp catabolic process GO:0033126 85 0.276
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.270
positive regulation of nucleoside metabolic process GO:0045979 91 0.262
purine nucleoside triphosphate catabolic process GO:0009146 203 0.245
regulation of nucleoside metabolic process GO:0009118 130 0.239
mitotic sister chromatid segregation GO:0000070 14 0.238
positive regulation of nucleotide catabolic process GO:0030813 88 0.237
mitotic nuclear division GO:0007067 48 0.228
regulation of gtp catabolic process GO:0033124 113 0.226
regulation of protein localization GO:0032880 231 0.206
mitotic cell cycle process GO:1903047 159 0.194
establishment of organelle localization GO:0051656 122 0.191
chromatin modification GO:0016568 187 0.183
cell division GO:0051301 120 0.180
ribose phosphate metabolic process GO:0019693 291 0.180
purine nucleoside catabolic process GO:0006152 205 0.172
regulation of dna dependent dna replication GO:0090329 8 0.167
Human
glycosyl compound catabolic process GO:1901658 206 0.164
nucleoside phosphate catabolic process GO:1901292 222 0.160
ribonucleotide catabolic process GO:0009261 208 0.157
organic cyclic compound catabolic process GO:1901361 295 0.157
cell cell junction organization GO:0045216 72 0.155
nucleus localization GO:0051647 20 0.152
positive regulation of nucleotide metabolic process GO:0045981 114 0.148
purine ribonucleotide catabolic process GO:0009154 208 0.146
nucleoside phosphate metabolic process GO:0006753 338 0.143
chromosome segregation GO:0007059 48 0.143
Human
leukocyte differentiation GO:0002521 342 0.142
organelle fission GO:0048285 170 0.142
purine nucleoside metabolic process GO:0042278 241 0.138
regulation of mitotic cell cycle GO:0007346 126 0.134
nuclear division GO:0000280 158 0.133
heterocycle catabolic process GO:0046700 280 0.132
mitotic cell cycle GO:0000278 195 0.131
blastocyst development GO:0001824 80 0.129
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.119
nucleotide metabolic process GO:0009117 332 0.117
purine nucleotide catabolic process GO:0006195 211 0.116
small gtpase mediated signal transduction GO:0007264 97 0.113
regulation of nucleotide metabolic process GO:0006140 169 0.112
rho protein signal transduction GO:0007266 32 0.110
nucleotide catabolic process GO:0009166 217 0.108
protein localization to organelle GO:0033365 185 0.106
cellular nitrogen compound catabolic process GO:0044270 280 0.104
purine ribonucleotide metabolic process GO:0009150 290 0.103
nucleobase containing small molecule metabolic process GO:0055086 352 0.100
neural tube development GO:0021915 160 0.099
carbohydrate derivative catabolic process GO:1901136 231 0.098
nucleoside triphosphate metabolic process GO:0009141 230 0.098
regulation of purine nucleotide catabolic process GO:0033121 122 0.097
purine nucleoside triphosphate metabolic process GO:0009144 226 0.097
negative regulation of mitotic cell cycle GO:0045930 58 0.097
microtubule based process GO:0007017 236 0.096
negative regulation of cell cycle GO:0045786 123 0.093
Human
purine containing compound metabolic process GO:0072521 311 0.093
defense response to other organism GO:0098542 197 0.093
regulation of ras gtpase activity GO:0032318 88 0.092
ribonucleoside triphosphate metabolic process GO:0009199 220 0.087
positive regulation of cell cycle process GO:0090068 61 0.087
carbohydrate derivative biosynthetic process GO:1901137 183 0.087
purine nucleotide metabolic process GO:0006163 302 0.086
developmental maturation GO:0021700 193 0.086
nucleoside triphosphate catabolic process GO:0009143 205 0.085
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.084
ribonucleoside metabolic process GO:0009119 245 0.084
circulatory system process GO:0003013 197 0.083
blood circulation GO:0008015 195 0.083
positive regulation of apoptotic process GO:0043065 217 0.083
purine containing compound catabolic process GO:0072523 213 0.079
negative regulation of cell cycle phase transition GO:1901988 48 0.078
positive regulation of ras gtpase activity GO:0032320 65 0.077
negative regulation of mapk cascade GO:0043409 65 0.075
regulation of cellular catabolic process GO:0031329 242 0.075
axon target recognition GO:0007412 4 0.072
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.071
multi multicellular organism process GO:0044706 109 0.071
sister chromatid segregation GO:0000819 20 0.071
regulation of nucleotide catabolic process GO:0030811 122 0.070
regulation of cell cycle GO:0051726 281 0.067
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.067
neuron apoptotic process GO:0051402 142 0.064
cellular response to dna damage stimulus GO:0006974 207 0.064
cell cycle checkpoint GO:0000075 47 0.063
negative regulation of neuron death GO:1901215 98 0.062
gtp metabolic process GO:0046039 144 0.062
regulation of mitotic sister chromatid segregation GO:0033047 12 0.061
nucleoside metabolic process GO:0009116 246 0.061
negative regulation of cell cycle process GO:0010948 69 0.060
Human
meiotic nuclear division GO:0007126 115 0.060
gtp catabolic process GO:0006184 143 0.060
myeloid cell homeostasis GO:0002262 114 0.060
dna metabolic process GO:0006259 303 0.058
Human
positive regulation of hydrolase activity GO:0051345 148 0.058
lymphocyte differentiation GO:0030098 242 0.057
positive regulation of cellular catabolic process GO:0031331 148 0.057
regulation of cell shape GO:0008360 39 0.057
cellular macromolecule catabolic process GO:0044265 206 0.057
development of primary sexual characteristics GO:0045137 143 0.056
gonad development GO:0008406 141 0.056
regulation of mapk cascade GO:0043408 248 0.056
glycosyl compound metabolic process GO:1901657 246 0.053
regulation of cell migration GO:0030334 219 0.052
centrosome cycle GO:0007098 23 0.051
rhythmic process GO:0048511 174 0.051
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.049
circadian rhythm GO:0007623 114 0.049
cell type specific apoptotic process GO:0097285 268 0.049
nuclear migration GO:0007097 6 0.048
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.047
ribonucleoside catabolic process GO:0042454 206 0.047
heart process GO:0003015 94 0.047
meiotic cell cycle process GO:1903046 77 0.046
regulation of response to wounding GO:1903034 189 0.045
negative regulation of molecular function GO:0044092 258 0.044
negative regulation of protein metabolic process GO:0051248 282 0.044
multicellular organism growth GO:0035264 161 0.044
positive regulation of adherens junction organization GO:1903393 5 0.042
protein modification by small protein removal GO:0070646 21 0.042
regulation of glucose metabolic process GO:0010906 60 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
myeloid cell differentiation GO:0030099 233 0.041
adult behavior GO:0030534 135 0.041
organonitrogen compound catabolic process GO:1901565 264 0.041
neurotransmitter secretion GO:0007269 62 0.039
neural precursor cell proliferation GO:0061351 121 0.039
regulation of neuron projection development GO:0010975 169 0.038
single organismal cell cell adhesion GO:0016337 131 0.038
regulation of mitotic cell cycle phase transition GO:1901990 73 0.037
blastocyst formation GO:0001825 33 0.037
positive regulation of rab gtpase activity GO:0032851 7 0.036
histone modification GO:0016570 159 0.036
cell maturation GO:0048469 127 0.035
neural tube formation GO:0001841 108 0.035
mitotic cell cycle checkpoint GO:0007093 31 0.034
regulation of organelle organization GO:0033043 289 0.034
regulation of cell activation GO:0050865 289 0.034
neuron death GO:0070997 154 0.034
chemotaxis GO:0006935 247 0.034
chromosome organization involved in meiosis GO:0070192 39 0.034
aromatic compound catabolic process GO:0019439 286 0.034
meiotic cell cycle GO:0051321 122 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.033
positive regulation of cell development GO:0010720 237 0.033
wound healing GO:0042060 157 0.032
morphogenesis of embryonic epithelium GO:0016331 159 0.032
response to growth factor GO:0070848 198 0.032
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.031
negative regulation of phosphorylation GO:0042326 166 0.031
cytokine production GO:0001816 319 0.030
regulation of stress activated mapk cascade GO:0032872 69 0.030
regulation of chromatin silencing GO:0031935 2 0.030
cell matrix adhesion GO:0007160 68 0.030
microtubule cytoskeleton organization GO:0000226 157 0.030
regulation of cell substrate adhesion GO:0010810 73 0.030
adherens junction organization GO:0034332 28 0.029
regulation of cell cycle phase transition GO:1901987 77 0.029
ribonucleoside monophosphate metabolic process GO:0009161 80 0.029
forebrain development GO:0030900 302 0.029
actin filament based movement GO:0030048 23 0.028
centrosome duplication GO:0051298 16 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
regulation of circadian rhythm GO:0042752 58 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
dna packaging GO:0006323 30 0.028
digestive system development GO:0055123 200 0.028
bone morphogenesis GO:0060349 78 0.027
regulation of cell junction assembly GO:1901888 14 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
stress activated protein kinase signaling cascade GO:0031098 81 0.027
regulation of system process GO:0044057 200 0.027
female gamete generation GO:0007292 74 0.026
regulation of secretion GO:0051046 274 0.026
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.026
regulation of neuron apoptotic process GO:0043523 122 0.026
maintenance of location GO:0051235 89 0.026
regulation of cellular response to stress GO:0080135 159 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
retina development in camera type eye GO:0060041 119 0.025
heart contraction GO:0060047 93 0.024
dna dependent dna replication GO:0006261 24 0.024
Human
transition metal ion homeostasis GO:0055076 54 0.024
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.024
nucleoside monophosphate metabolic process GO:0009123 85 0.024
regulation of transferase activity GO:0051338 263 0.024
cellular ketone metabolic process GO:0042180 84 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.023
negative regulation of exocytosis GO:0045920 12 0.023
regulation of neuron death GO:1901214 134 0.023
negative regulation of ossification GO:0030279 49 0.023
dna conformation change GO:0071103 37 0.023
leukocyte migration GO:0050900 124 0.023
negative regulation of neuron apoptotic process GO:0043524 92 0.022
chromatin organization GO:0006325 206 0.022
regulation of intracellular transport GO:0032386 159 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
axonogenesis GO:0007409 274 0.022
dna repair GO:0006281 107 0.022
cellular homeostasis GO:0019725 240 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
monosaccharide metabolic process GO:0005996 106 0.022
tube formation GO:0035148 140 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
protein autophosphorylation GO:0046777 61 0.022
cellular amine metabolic process GO:0044106 44 0.021
regionalization GO:0003002 337 0.021
positive regulation of wound healing GO:0090303 17 0.021
protein deubiquitination GO:0016579 19 0.021
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.021
regulation of kinase activity GO:0043549 249 0.021
embryonic epithelial tube formation GO:0001838 130 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
epithelial cell development GO:0002064 159 0.021
ossification GO:0001503 216 0.020
cellular amino acid metabolic process GO:0006520 103 0.020
dendrite development GO:0016358 115 0.020
regulation of hydrolase activity GO:0051336 246 0.020
regulation of chromosome segregation GO:0051983 21 0.020
spindle assembly involved in meiosis GO:0090306 4 0.019
dephosphorylation GO:0016311 129 0.019
sensory organ morphogenesis GO:0090596 242 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
positive regulation of secretion GO:0051047 130 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
regulation of nuclear division GO:0051783 56 0.019
regulation of neural precursor cell proliferation GO:2000177 70 0.019
regulation of dna replication GO:0006275 17 0.019
Human
amine metabolic process GO:0009308 45 0.019
ribonucleoside monophosphate catabolic process GO:0009158 57 0.019
synaptic transmission GO:0007268 329 0.019
cell substrate adherens junction assembly GO:0007045 19 0.018
covalent chromatin modification GO:0016569 163 0.018
regulation of membrane potential GO:0042391 192 0.018
cell junction assembly GO:0034329 52 0.018
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
oocyte construction GO:0007308 2 0.017
multi organism reproductive behavior GO:0044705 29 0.017
organelle assembly GO:0070925 177 0.017
lung field specification GO:0060424 3 0.017
carbohydrate metabolic process GO:0005975 230 0.017
response to light stimulus GO:0009416 135 0.017
endothelial cell differentiation GO:0045446 41 0.017
immune effector process GO:0002252 321 0.017
regulation of neuron differentiation GO:0045664 281 0.017
stem cell maintenance GO:0019827 130 0.017
negative regulation of protein modification process GO:0031400 163 0.017
positive regulation of cell death GO:0010942 224 0.017
negative regulation of immune system process GO:0002683 209 0.016
glycosylation GO:0070085 62 0.016
ion transmembrane transport GO:0034220 361 0.016
response to organonitrogen compound GO:0010243 246 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
muscle cell differentiation GO:0042692 261 0.016
transmembrane transport GO:0055085 412 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of rab protein signal transduction GO:0032483 8 0.016
positive regulation of cell adhesion GO:0045785 80 0.016
wnt signaling pathway GO:0016055 188 0.016
mitotic chromosome condensation GO:0007076 1 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.016
membrane organization GO:0061024 245 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
protein oligomerization GO:0051259 67 0.015
actin cytoskeleton reorganization GO:0031532 21 0.015
negative regulation of chromatin silencing GO:0031936 1 0.015
mitotic cytokinesis GO:0000281 4 0.015
regulation of protein transport GO:0051223 163 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
chromatin remodeling at centromere GO:0031055 2 0.015
regulation of protein autophosphorylation GO:0031952 8 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
epidermis development GO:0008544 187 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
morphogenesis of a polarized epithelium GO:0001738 37 0.015
actin filament organization GO:0007015 113 0.014
lipid localization GO:0010876 126 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
actin mediated cell contraction GO:0070252 15 0.014
multicellular organismal reproductive behavior GO:0033057 23 0.014
endothelial cell development GO:0001885 20 0.014
body morphogenesis GO:0010171 45 0.014
leukocyte tethering or rolling GO:0050901 3 0.014
b cell activation GO:0042113 161 0.014
cellular lipid metabolic process GO:0044255 323 0.014
regulation of sister chromatid segregation GO:0033045 13 0.014
protein heterooligomerization GO:0051291 14 0.014
regulation of defense response GO:0031347 233 0.014
nitrogen compound transport GO:0071705 271 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
cellular chemical homeostasis GO:0055082 215 0.014
positive regulation of actin filament bundle assembly GO:0032233 11 0.014
leukocyte proliferation GO:0070661 172 0.014
regulation of vesicle mediated transport GO:0060627 139 0.013
single organism cell adhesion GO:0098602 156 0.013
regulation of carbohydrate biosynthetic process GO:0043255 40 0.013
jnk cascade GO:0007254 72 0.013
regulation of establishment of planar polarity GO:0090175 28 0.013
cell adhesion GO:0007155 329 0.013
calcium ion dependent exocytosis GO:0017156 35 0.013
apoptotic signaling pathway GO:0097190 306 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
retina morphogenesis in camera type eye GO:0060042 45 0.013
protein localization to chromosome GO:0034502 6 0.013
multi organism behavior GO:0051705 62 0.013
adherens junction assembly GO:0034333 22 0.013
parental behavior GO:0060746 11 0.013
calcium ion homeostasis GO:0055074 127 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
monosaccharide biosynthetic process GO:0046364 44 0.013
regulation of jnk cascade GO:0046328 62 0.013
maintenance of location in cell GO:0051651 24 0.012
digestive tract morphogenesis GO:0048546 147 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
muscle system process GO:0003012 141 0.012
glycoprotein metabolic process GO:0009100 116 0.012
regulation of chromosome organization GO:0033044 83 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
trophectodermal cell differentiation GO:0001829 21 0.012
fertilization GO:0009566 127 0.012
protein localization to chromatin GO:0071168 3 0.012
regulation of innate immune response GO:0045088 91 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
regulation of ossification GO:0030278 112 0.012
definitive hemopoiesis GO:0060216 20 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
regulation of b cell activation GO:0050864 81 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
spindle assembly involved in female meiosis GO:0007056 3 0.012
macromolecule glycosylation GO:0043413 55 0.012
primary neural tube formation GO:0014020 95 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
mapk cascade GO:0000165 281 0.011
stem cell development GO:0048864 219 0.011
synaptic vesicle localization GO:0097479 59 0.011
meiosis ii GO:0007135 7 0.011
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.011
regulation of cell projection organization GO:0031344 206 0.011
stress activated mapk cascade GO:0051403 80 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
gastrulation GO:0007369 116 0.011
endocytosis GO:0006897 168 0.011
positive regulation of protein transport GO:0051222 93 0.011
response to radiation GO:0009314 165 0.011
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.011
metaphase plate congression GO:0051310 2 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of cell motility GO:2000145 236 0.011
hexose biosynthetic process GO:0019319 39 0.011
lateral mesodermal cell fate commitment GO:0048372 2 0.011
intra s dna damage checkpoint GO:0031573 4 0.010
negative regulation of lymphocyte proliferation GO:0050672 45 0.010
defecation GO:0030421 1 0.010
homeostasis of number of cells GO:0048872 210 0.010
granulocyte differentiation GO:0030851 17 0.010
negative regulation of leukocyte proliferation GO:0070664 46 0.010
memory GO:0007613 58 0.010
regulation of rab gtpase activity GO:0032313 8 0.010
neural tube closure GO:0001843 90 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
regulation of ras protein signal transduction GO:0046578 114 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010

Stag2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.281
nervous system disease DOID:863 0 0.281
sensory system disease DOID:0050155 0 0.155
eye and adnexa disease DOID:1492 0 0.116
eye disease DOID:5614 0 0.116
central nervous system disease DOID:331 0 0.077
neurodegenerative disease DOID:1289 0 0.077
retinal disease DOID:5679 0 0.030
retinal degeneration DOID:8466 0 0.016
cornelia de lange syndrome DOID:11725 0 0.010