Mus musculus

0 known processes

Hist2h4

histone cluster 2, H4

(Aliases: X04652,H4)

Hist2h4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 206 0.137
protein dna complex disassembly GO:0032986 1 0.122
protein dna complex subunit organization GO:0071824 28 0.117
regulation of cellular amino acid metabolic process GO:0006521 5 0.109
cellular ketone metabolic process GO:0042180 84 0.107
negative regulation of protein metabolic process GO:0051248 282 0.100
cellular response to dna damage stimulus GO:0006974 207 0.097
covalent chromatin modification GO:0016569 163 0.086
dna packaging GO:0006323 30 0.085
regulation of cellular ketone metabolic process GO:0010565 66 0.085
dna metabolic process GO:0006259 303 0.085
chromatin modification GO:0016568 187 0.078
negative regulation of protein maturation GO:1903318 79 0.076
negative regulation of cellular protein metabolic process GO:0032269 247 0.076
dna repair GO:0006281 107 0.075
amine metabolic process GO:0009308 45 0.070
nucleosome disassembly GO:0006337 1 0.069
chromatin assembly or disassembly GO:0006333 16 0.067
protein maturation GO:0051604 176 0.066
regulation of cellular amine metabolic process GO:0033238 20 0.066
chromatin assembly GO:0031497 13 0.065
cellular protein catabolic process GO:0044257 155 0.063
cellular amino acid metabolic process GO:0006520 103 0.062
muscle cell differentiation GO:0042692 261 0.061
protein processing GO:0016485 163 0.061
meiotic cell cycle process GO:1903046 77 0.060
regulation of chromosome organization GO:0033044 83 0.057
dna conformation change GO:0071103 37 0.056
regulation of organelle organization GO:0033043 289 0.055
negative regulation of protein processing GO:0010955 79 0.052
ossification GO:0001503 216 0.052
mitotic cell cycle GO:0000278 195 0.050
cellular amine metabolic process GO:0044106 44 0.050
mitotic cell cycle checkpoint GO:0007093 31 0.049
synaptic vesicle localization GO:0097479 59 0.048
gene silencing GO:0016458 38 0.047
monocarboxylic acid metabolic process GO:0032787 191 0.047
cellular macromolecule catabolic process GO:0044265 206 0.046
negative regulation of proteolysis GO:0045861 74 0.046
synaptic transmission GO:0007268 329 0.045
aromatic compound catabolic process GO:0019439 286 0.045
regulation of mitotic cell cycle phase transition GO:1901990 73 0.045
negative regulation of organelle organization GO:0010639 90 0.044
modification dependent macromolecule catabolic process GO:0043632 133 0.044
negative regulation of molecular function GO:0044092 258 0.044
lipid homeostasis GO:0055088 63 0.044
triglyceride homeostasis GO:0070328 15 0.044
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.041
negative regulation of cell cycle GO:0045786 123 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.041
histone modification GO:0016570 159 0.041
carbohydrate derivative catabolic process GO:1901136 231 0.040
mitotic cell cycle process GO:1903047 159 0.040
organelle localization GO:0051640 179 0.038
regulation of cell cycle phase transition GO:1901987 77 0.038
response to organonitrogen compound GO:0010243 246 0.038
regulation of protein processing GO:0070613 96 0.038
autophagy GO:0006914 45 0.038
vesicle localization GO:0051648 86 0.038
regulation of cell cycle process GO:0010564 160 0.037
carbohydrate metabolic process GO:0005975 230 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.036
leukocyte differentiation GO:0002521 342 0.036
proteasomal protein catabolic process GO:0010498 98 0.035
cellular lipid metabolic process GO:0044255 323 0.035
macromolecule catabolic process GO:0009057 281 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.034
organophosphate catabolic process GO:0046434 232 0.033
organelle fission GO:0048285 170 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
negative regulation of chromosome organization GO:2001251 30 0.033
acylglycerol homeostasis GO:0055090 16 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
nucleotide metabolic process GO:0009117 332 0.032
cellular response to organonitrogen compound GO:0071417 145 0.032
regulation of cell division GO:0051302 76 0.032
regulation of cell cycle GO:0051726 281 0.032
lipid biosynthetic process GO:0008610 179 0.031
striated muscle tissue development GO:0014706 293 0.031
response to peptide GO:1901652 136 0.031
nucleoside metabolic process GO:0009116 246 0.031
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.031
regulation of cellular protein catabolic process GO:1903362 61 0.031
cell division GO:0051301 120 0.030
nuclear division GO:0000280 158 0.030
heterocycle catabolic process GO:0046700 280 0.030
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.030
protein modification by small protein conjugation or removal GO:0070647 207 0.030
negative regulation of cell cycle phase transition GO:1901988 48 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.029
meiotic cell cycle GO:0051321 122 0.029
myeloid cell differentiation GO:0030099 233 0.029
synapse organization GO:0050808 125 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
organonitrogen compound catabolic process GO:1901565 264 0.027
response to insulin GO:0032868 100 0.027
regulation of sister chromatid segregation GO:0033045 13 0.027
regulation of chromatin silencing GO:0031935 2 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
organic cyclic compound catabolic process GO:1901361 295 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
negative regulation of protein modification process GO:0031400 163 0.026
cellular homeostasis GO:0019725 240 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
negative regulation of nuclear division GO:0051784 19 0.026
regulation of leukocyte differentiation GO:1902105 159 0.025
inflammatory response GO:0006954 244 0.025
cytokine production GO:0001816 319 0.025
cell cycle checkpoint GO:0000075 47 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
regulation of kinase activity GO:0043549 249 0.025
cellular response to lipid GO:0071396 145 0.025
oxidation reduction process GO:0055114 342 0.025
response to peptide hormone GO:0043434 127 0.025
small molecule biosynthetic process GO:0044283 132 0.025
male gamete generation GO:0048232 285 0.025
apoptotic signaling pathway GO:0097190 306 0.025
nucleoside catabolic process GO:0009164 206 0.025
ribonucleotide catabolic process GO:0009261 208 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
lymphocyte differentiation GO:0030098 242 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
germ cell development GO:0007281 185 0.024
fat cell differentiation GO:0045444 160 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
reactive oxygen species biosynthetic process GO:1903409 8 0.023
immune effector process GO:0002252 321 0.023
hexose metabolic process GO:0019318 98 0.023
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.023
fatty acid metabolic process GO:0006631 121 0.023
regulation of nuclear division GO:0051783 56 0.023
regulation of cytokine production GO:0001817 266 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
asymmetric stem cell division GO:0098722 3 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
lateral inhibition GO:0046331 1 0.022
regulation of muscle tissue development GO:1901861 97 0.022
cellular chemical homeostasis GO:0055082 215 0.021
negative regulation of mitotic cell cycle GO:0045930 58 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
regulation of myeloid cell differentiation GO:0045637 96 0.021
positive regulation of cell death GO:0010942 224 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
t cell activation GO:0042110 289 0.020
regulation of protein kinase activity GO:0045859 232 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
positive regulation of protein modification process GO:0031401 299 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
regulation of proteolysis GO:0030162 164 0.020
internal protein amino acid acetylation GO:0006475 42 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.020
central nervous system neuron differentiation GO:0021953 162 0.020
protein targeting GO:0006605 143 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
regulation of cell activation GO:0050865 289 0.020
leukocyte proliferation GO:0070661 172 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
protein catabolic process GO:0030163 221 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
regulation of protein localization GO:0032880 231 0.019
urogenital system development GO:0001655 261 0.019
response to radiation GO:0009314 165 0.019
cation transport GO:0006812 399 0.019
negative regulation of cell cycle process GO:0010948 69 0.019
regulation of protein maturation GO:1903317 96 0.019
peptidyl amino acid modification GO:0018193 336 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
peptidyl lysine modification GO:0018205 77 0.019
peptidyl lysine acetylation GO:0018394 45 0.019
response to lipopolysaccharide GO:0032496 128 0.019
maintenance of location GO:0051235 89 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
chromatin silencing GO:0006342 15 0.019
spermatogenesis GO:0007283 284 0.019
nucleoside monophosphate catabolic process GO:0009125 59 0.018
protein ubiquitination GO:0016567 171 0.018
innate immune response GO:0045087 157 0.018
response to inorganic substance GO:0010035 96 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
camera type eye development GO:0043010 266 0.018
cell growth GO:0016049 130 0.018
organic acid biosynthetic process GO:0016053 86 0.018
multicellular organism growth GO:0035264 161 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
transmembrane transport GO:0055085 412 0.017
cellular response to peptide GO:1901653 92 0.017
purine containing compound metabolic process GO:0072521 311 0.017
response to acid chemical GO:0001101 111 0.017
regulation of protein catabolic process GO:0042176 108 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.017
nitrogen compound transport GO:0071705 271 0.017
cellular response to insulin stimulus GO:0032869 78 0.017
positive regulation of cell activation GO:0050867 158 0.017
regulation of mitosis GO:0007088 29 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
regulation of cellular component size GO:0032535 121 0.017
monocarboxylic acid biosynthetic process GO:0072330 61 0.017
atp catabolic process GO:0006200 55 0.017
negative regulation of protein catabolic process GO:0042177 36 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of mitotic sister chromatid segregation GO:0033047 12 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
chromosome separation GO:0051304 14 0.016
mapk cascade GO:0000165 281 0.016
regulation of anatomical structure size GO:0090066 178 0.016
development of primary sexual characteristics GO:0045137 143 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.016
protein methylation GO:0006479 81 0.016
regulation of binding GO:0051098 111 0.016
positive regulation of cell cycle GO:0045787 92 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
protein import GO:0017038 101 0.016
protein localization to organelle GO:0033365 185 0.016
inter male aggressive behavior GO:0002121 3 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
regulation of defense response GO:0031347 233 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
renal system development GO:0072001 225 0.015
nucleosome assembly GO:0006334 7 0.015
connective tissue development GO:0061448 179 0.015
purine containing compound catabolic process GO:0072523 213 0.015
regulation of intracellular transport GO:0032386 159 0.015
rrna transcription GO:0009303 9 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
stem cell differentiation GO:0048863 268 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
compound eye development GO:0048749 1 0.015
respiratory system development GO:0060541 190 0.015
regulation of cell growth GO:0001558 91 0.015
negative regulation of transferase activity GO:0051348 85 0.015
mitotic sister chromatid separation GO:0051306 9 0.015
response to organic cyclic compound GO:0014070 198 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
negative regulation of immune system process GO:0002683 209 0.015
ras protein signal transduction GO:0007265 77 0.015
b cell activation GO:0042113 161 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
glucose metabolic process GO:0006006 92 0.015
antimicrobial peptide biosynthetic process GO:0002777 2 0.015
cell adhesion GO:0007155 329 0.015
skeletal system development GO:0001501 356 0.014
methylation GO:0032259 134 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
atp metabolic process GO:0046034 75 0.014
regulation of ossification GO:0030278 112 0.014
negative regulation of chromatin silencing GO:0031936 1 0.014
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
regulation of ion transport GO:0043269 215 0.014
regulation of response to wounding GO:1903034 189 0.014
intracellular protein transport GO:0006886 204 0.014
spermatid development GO:0007286 108 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
muscle tissue development GO:0060537 308 0.014
neuromuscular synaptic transmission GO:0007274 16 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
positive regulation of organelle organization GO:0010638 128 0.014
microtubule based process GO:0007017 236 0.014
chromosome segregation GO:0007059 48 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
positive regulation of nervous system development GO:0051962 221 0.014
response to growth factor GO:0070848 198 0.014
forebrain development GO:0030900 302 0.014
positive regulation of cytokine production GO:0001819 174 0.014
divalent inorganic cation transport GO:0072511 178 0.014
nucleotide excision repair GO:0006289 13 0.014
lymphocyte proliferation GO:0046651 164 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
response to oxygen levels GO:0070482 62 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
negative regulation of cell development GO:0010721 169 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
cell type specific apoptotic process GO:0097285 268 0.013
antimicrobial peptide production GO:0002775 2 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
spermatid differentiation GO:0048515 115 0.013
protein acylation GO:0043543 64 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
cellular alcohol metabolic process GO:0044107 3 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
cellular response to acid chemical GO:0071229 68 0.013
lung development GO:0030324 164 0.013
peptide transport GO:0015833 133 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of secretion GO:0051046 274 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of transferase activity GO:0051338 263 0.013
sensory perception GO:0007600 245 0.013
skeletal muscle organ development GO:0060538 163 0.013
leukocyte migration GO:0050900 124 0.013
membrane organization GO:0061024 245 0.013
cell fate commitment GO:0045165 210 0.013
regulation of hormone levels GO:0010817 211 0.013
nuclear import GO:0051170 95 0.013
protein localization to nucleus GO:0034504 121 0.013
stem cell development GO:0048864 219 0.013
striated muscle cell development GO:0055002 125 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.012
multicellular organismal signaling GO:0035637 91 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
digestive system development GO:0055123 200 0.012
fatty acid biosynthetic process GO:0006633 41 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
dna replication independent nucleosome assembly GO:0006336 1 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
divalent metal ion transport GO:0070838 172 0.012
response to light stimulus GO:0009416 135 0.012
regulation of chromatin modification GO:1903308 57 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.012
macromolecule methylation GO:0043414 120 0.012
regulation of chromosome segregation GO:0051983 21 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
myotube cell development GO:0014904 60 0.012
cytoplasmic transport GO:0016482 234 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
histone lysine methylation GO:0034968 50 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
nucleotide catabolic process GO:0009166 217 0.012
b cell differentiation GO:0030183 78 0.012
translation GO:0006412 93 0.012
positive regulation of cell development GO:0010720 237 0.012
calcium ion transport GO:0006816 159 0.012
positive regulation of leukocyte differentiation GO:1902107 86 0.012
sister chromatid segregation GO:0000819 20 0.011
rna processing GO:0006396 105 0.011
internal peptidyl lysine acetylation GO:0018393 42 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
gland development GO:0048732 330 0.011
sequestering of calcium ion GO:0051208 18 0.011
histone acetylation GO:0016573 41 0.011
extracellular structure organization GO:0043062 148 0.011
mitotic nuclear division GO:0007067 48 0.011
endomembrane system organization GO:0010256 147 0.011
extracellular matrix organization GO:0030198 147 0.011
cell substrate adhesion GO:0031589 130 0.011
positive regulation of binding GO:0051099 49 0.011
secondary alcohol metabolic process GO:1902652 3 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
angiogenesis GO:0001525 201 0.011
transmission of nerve impulse GO:0019226 76 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
meiotic nuclear division GO:0007126 115 0.011
dna recombination GO:0006310 92 0.011
mitotic sister chromatid segregation GO:0000070 14 0.011
sequestering of metal ion GO:0051238 19 0.011
chromatin disassembly GO:0031498 1 0.011
regulation of histone modification GO:0031056 56 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of cell motility GO:2000145 236 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
negative regulation of endopeptidase activity GO:0010951 44 0.011
monosaccharide metabolic process GO:0005996 106 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
positive regulation of t cell activation GO:0050870 101 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
leukocyte mediated immunity GO:0002443 174 0.011
negative regulation of cellular protein catabolic process GO:1903363 22 0.011
zymogen activation GO:0031638 41 0.011
regionalization GO:0003002 337 0.011
blood vessel morphogenesis GO:0048514 285 0.011
developmental maturation GO:0021700 193 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of cell projection organization GO:0031344 206 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
cation homeostasis GO:0055080 212 0.011
asymmetric neuroblast division GO:0055059 1 0.011
myotube differentiation GO:0014902 105 0.011
regulation of cell adhesion GO:0030155 154 0.011
activation of immune response GO:0002253 138 0.010
response to transforming growth factor beta GO:0071559 88 0.010
regulation of chromatin organization GO:1902275 57 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
blood circulation GO:0008015 195 0.010
ameboidal type cell migration GO:0001667 128 0.010
muscle fiber development GO:0048747 76 0.010
cell activation involved in immune response GO:0002263 126 0.010
lipid localization GO:0010876 126 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.010
regulation of fatty acid metabolic process GO:0019217 28 0.010
mrna metabolic process GO:0016071 84 0.010
sulfur compound metabolic process GO:0006790 100 0.010
rhythmic process GO:0048511 174 0.010
t cell differentiation GO:0030217 174 0.010
respiratory tube development GO:0030323 167 0.010
tissue homeostasis GO:0001894 115 0.010
mitotic spindle checkpoint GO:0071174 9 0.010
locomotory behavior GO:0007626 195 0.010
regulation of fat cell differentiation GO:0045598 81 0.010

Hist2h4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.012
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010