Mus musculus

0 known processes

Rspo4

R-spondin family, member 4

(Aliases: A930029K19Rik,A730099F22)

Rspo4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
forebrain development GO:0030900 302 0.092
inorganic cation transmembrane transport GO:0098662 207 0.088
spermatogenesis GO:0007283 284 0.086
transmembrane transport GO:0055085 412 0.075
cell type specific apoptotic process GO:0097285 268 0.075
protein processing GO:0016485 163 0.066
developmental maturation GO:0021700 193 0.064
macromolecule catabolic process GO:0009057 281 0.061
cell fate commitment GO:0045165 210 0.056
regulation of cell cycle GO:0051726 281 0.056
cation transmembrane transport GO:0098655 266 0.053
male gamete generation GO:0048232 285 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.046
cellular amino acid metabolic process GO:0006520 103 0.046
ion transmembrane transport GO:0034220 361 0.045
skeletal system morphogenesis GO:0048705 203 0.045
protein maturation GO:0051604 176 0.043
central nervous system neuron differentiation GO:0021953 162 0.042
protein catabolic process GO:0030163 221 0.040
placenta development GO:0001890 140 0.039
skeletal system development GO:0001501 356 0.038
cellular macromolecule catabolic process GO:0044265 206 0.037
single organism cell adhesion GO:0098602 156 0.037
ossification GO:0001503 216 0.037
spermatid differentiation GO:0048515 115 0.036
regulation of membrane potential GO:0042391 192 0.036
cellular homeostasis GO:0019725 240 0.036
camera type eye development GO:0043010 266 0.036
cell adhesion GO:0007155 329 0.035
cation transport GO:0006812 399 0.035
negative regulation of cellular component organization GO:0051129 194 0.034
t cell activation GO:0042110 289 0.034
regulation of retina development in camera type eye GO:1902866 3 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.033
regulation of cell cycle process GO:0010564 160 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
response to organic cyclic compound GO:0014070 198 0.031
cellular ion homeostasis GO:0006873 165 0.031
mapk cascade GO:0000165 281 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
metal ion homeostasis GO:0055065 189 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
synaptic transmission GO:0007268 329 0.029
protein ubiquitination GO:0016567 171 0.029
positive regulation of nervous system development GO:0051962 221 0.028
cartilage development GO:0051216 140 0.028
cell junction organization GO:0034330 77 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
gland development GO:0048732 330 0.027
response to organonitrogen compound GO:0010243 246 0.027
regulation of organelle organization GO:0033043 289 0.027
inorganic ion transmembrane transport GO:0098660 234 0.026
stem cell development GO:0048864 219 0.026
kidney development GO:0001822 213 0.026
positive regulation of neuron differentiation GO:0045666 141 0.026
leukocyte differentiation GO:0002521 342 0.026
cellular response to lipid GO:0071396 145 0.025
amine metabolic process GO:0009308 45 0.025
fat cell differentiation GO:0045444 160 0.025
dephosphorylation GO:0016311 129 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
divalent inorganic cation transport GO:0072511 178 0.024
regulation of proteolysis GO:0030162 164 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
organelle fission GO:0048285 170 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.024
stem cell maintenance GO:0019827 130 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
bone mineralization GO:0030282 54 0.024
urogenital system development GO:0001655 261 0.024
cellular ketone metabolic process GO:0042180 84 0.023
connective tissue development GO:0061448 179 0.023
nuclear division GO:0000280 158 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
cellular protein catabolic process GO:0044257 155 0.023
response to inorganic substance GO:0010035 96 0.022
renal system development GO:0072001 225 0.022
interleukin 8 secretion GO:0072606 3 0.022
regulation of interleukin 8 production GO:0032677 3 0.022
regionalization GO:0003002 337 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
positive regulation of cell development GO:0010720 237 0.022
cation homeostasis GO:0055080 212 0.022
interleukin 8 production GO:0032637 4 0.022
reactive nitrogen species metabolic process GO:2001057 0 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
cell maturation GO:0048469 127 0.021
somatotropin secreting cell differentiation GO:0060126 4 0.021
ubiquitin dependent protein catabolic process GO:0006511 129 0.021
regulation of protein localization GO:0032880 231 0.021
chromatin organization GO:0006325 206 0.021
regulation of synapse structural plasticity GO:0051823 4 0.021
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.020
apoptotic signaling pathway GO:0097190 306 0.020
sensory perception GO:0007600 245 0.020
purine containing compound metabolic process GO:0072521 311 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
sensory perception of mechanical stimulus GO:0050954 107 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
regulation of ossification GO:0030278 112 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
negative regulation of cell cycle GO:0045786 123 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
regulation of interleukin 1 alpha production GO:0032650 4 0.020
mesoderm development GO:0007498 100 0.019
epithelial cell development GO:0002064 159 0.019
regulation of anatomical structure size GO:0090066 178 0.019
regulation of cell activation GO:0050865 289 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
cognition GO:0050890 149 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
immune effector process GO:0002252 321 0.019
chondrocyte differentiation GO:0002062 72 0.019
germ cell development GO:0007281 185 0.019
mesonephric epithelium development GO:0072163 94 0.019
cellular response to cytokine stimulus GO:0071345 189 0.018
lateral inhibition GO:0046331 1 0.018
endocytosis GO:0006897 168 0.018
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.018
cell growth GO:0016049 130 0.018
regulation of interleukin 8 secretion GO:2000482 2 0.018
endomembrane system organization GO:0010256 147 0.018
stem cell differentiation GO:0048863 268 0.018
cellular amine metabolic process GO:0044106 44 0.018
inflammatory response GO:0006954 244 0.018
membrane organization GO:0061024 245 0.018
heart morphogenesis GO:0003007 178 0.018
regulation of system process GO:0044057 200 0.017
cytokine production GO:0001816 319 0.017
oocyte axis specification GO:0007309 2 0.017
circulatory system process GO:0003013 197 0.017
sensory organ morphogenesis GO:0090596 242 0.017
formation of primary germ layer GO:0001704 77 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
heterocycle catabolic process GO:0046700 280 0.017
response to extracellular stimulus GO:0009991 127 0.017
wnt signaling pathway GO:0016055 188 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
aromatic compound catabolic process GO:0019439 286 0.017
learning or memory GO:0007611 148 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
regulation of secretion by cell GO:1903530 249 0.016
wound healing GO:0042060 157 0.016
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
homeostasis of number of cells GO:0048872 210 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
positive regulation of cell death GO:0010942 224 0.016
skeletal muscle organ development GO:0060538 163 0.016
divalent metal ion transport GO:0070838 172 0.016
regulation of protein catabolic process GO:0042176 108 0.016
regulation of multi organism process GO:0043900 111 0.016
response to acid chemical GO:0001101 111 0.016
neural retina development GO:0003407 41 0.016
intracellular protein transport GO:0006886 204 0.016
cellular protein complex assembly GO:0043623 116 0.016
response to metal ion GO:0010038 47 0.016
regulation of cellular component biogenesis GO:0044087 181 0.015
embryonic skeletal system development GO:0048706 120 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
defecation GO:0030421 1 0.015
t cell differentiation GO:0030217 174 0.015
kidney epithelium development GO:0072073 121 0.015
neuroblast differentiation GO:0014016 2 0.015
regulation of neuron differentiation GO:0045664 281 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
regulation of neural retina development GO:0061074 3 0.015
locomotory behavior GO:0007626 195 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
odontogenesis GO:0042476 78 0.015
nucleoside metabolic process GO:0009116 246 0.014
organ growth GO:0035265 117 0.014
leukocyte proliferation GO:0070661 172 0.014
response to growth factor GO:0070848 198 0.014
regulation of stem cell differentiation GO:2000736 50 0.014
compound eye development GO:0048749 1 0.014
positive regulation of proteolysis GO:0045862 85 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.014
asymmetric stem cell division GO:0098722 3 0.014
mesenchyme development GO:0060485 152 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
striated muscle tissue development GO:0014706 293 0.014
epithelial tube formation GO:0072175 130 0.014
transmission of nerve impulse GO:0019226 76 0.014
meiotic nuclear division GO:0007126 115 0.014
cellular response to external stimulus GO:0071496 88 0.013
regulation of peptidase activity GO:0052547 96 0.013
regulation of mapk cascade GO:0043408 248 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
renal vesicle induction GO:0072034 3 0.013
sensory perception of sound GO:0007605 97 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
hexose metabolic process GO:0019318 98 0.013
dna metabolic process GO:0006259 303 0.013
regulation of hydrolase activity GO:0051336 246 0.013
defense response to other organism GO:0098542 197 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
male sex differentiation GO:0046661 109 0.013
regulation of chromosome organization GO:0033044 83 0.013
meiotic cell cycle GO:0051321 122 0.013
endocrine system development GO:0035270 98 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
dendrite development GO:0016358 115 0.013
spinal cord development GO:0021510 81 0.013
cardiac chamber morphogenesis GO:0003206 93 0.013
epidermis development GO:0008544 187 0.012
determination of left right symmetry GO:0007368 80 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
muscle tissue development GO:0060537 308 0.012
oxidation reduction process GO:0055114 342 0.012
cardiac muscle tissue development GO:0048738 130 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.012
cell division GO:0051301 120 0.012
mitotic cell cycle process GO:1903047 159 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
rhythmic process GO:0048511 174 0.012
regulation of protein transport GO:0051223 163 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
cardiac endothelial cell differentiation GO:0003348 4 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
positive regulation of organelle organization GO:0010638 128 0.012
oocyte construction GO:0007308 2 0.012
anatomical structure homeostasis GO:0060249 145 0.012
defense response to bacterium GO:0042742 119 0.012
intracellular mrna localization GO:0008298 4 0.012
midgut development GO:0007494 4 0.012
spermatid development GO:0007286 108 0.012
histone modification GO:0016570 159 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of defense response GO:0031347 233 0.012
cellular response to nutrient levels GO:0031669 64 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
mesonephric tubule development GO:0072164 94 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
regulation of protein stability GO:0031647 52 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
potassium ion transport GO:0006813 52 0.012
stem cell fate specification GO:0048866 3 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of transmembrane transport GO:0034762 128 0.012
covalent chromatin modification GO:0016569 163 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
multi multicellular organism process GO:0044706 109 0.011
pole plasm assembly GO:0007315 2 0.011
nucleotide metabolic process GO:0009117 332 0.011
response to starvation GO:0042594 65 0.011
neuron apoptotic process GO:0051402 142 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
forebrain generation of neurons GO:0021872 63 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
ureter morphogenesis GO:0072197 4 0.011
establishment or maintenance of neuroblast polarity GO:0045196 1 0.011
establishment of blood nerve barrier GO:0008065 3 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
response to oxygen levels GO:0070482 62 0.011
notch signaling pathway GO:0007219 71 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
regulation of secretion GO:0051046 274 0.011
regulation of translation GO:0006417 71 0.011
protein localization to plasma membrane GO:0072659 57 0.011
uterus morphogenesis GO:0061038 2 0.011
protein targeting GO:0006605 143 0.011
learning GO:0007612 98 0.011
neural tube formation GO:0001841 108 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
potassium ion transmembrane transport GO:0071805 43 0.011
monosaccharide metabolic process GO:0005996 106 0.011
bmp signaling pathway GO:0030509 93 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
gastrulation GO:0007369 116 0.011
respiratory tube development GO:0030323 167 0.011
retina development in camera type eye GO:0060041 119 0.011
prostate gland morphogenetic growth GO:0060737 4 0.011
rho protein signal transduction GO:0007266 32 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
regulation of protein maturation GO:1903317 96 0.011
lipid biosynthetic process GO:0008610 179 0.011
respiratory system development GO:0060541 190 0.011
actin cytoskeleton organization GO:0030036 220 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
response to peptide GO:1901652 136 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
blood circulation GO:0008015 195 0.011
positive regulation of cell cycle GO:0045787 92 0.011
interspecies interaction between organisms GO:0044419 83 0.011
astrocyte fate commitment GO:0060018 4 0.011
regulation of cell adhesion GO:0030155 154 0.011
defense response to virus GO:0051607 68 0.010
cellular response to metal ion GO:0071248 31 0.010
plasma membrane organization GO:0007009 90 0.010
mesonephros development GO:0001823 97 0.010
negative regulation of secretion by cell GO:1903531 54 0.010
lymphocyte differentiation GO:0030098 242 0.010
regulation of cardiac cell fate specification GO:2000043 1 0.010
carbohydrate metabolic process GO:0005975 230 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
telencephalon development GO:0021537 186 0.010
endodermal cell fate specification GO:0001714 4 0.010
mesodermal cell migration GO:0008078 4 0.010
embryonic appendage morphogenesis GO:0035113 126 0.010
appendage development GO:0048736 166 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.010
regulation of homeostatic process GO:0032844 182 0.010
transforming growth factor beta2 production GO:0032906 2 0.010
negative regulation of wnt signaling pathway GO:0030178 73 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
sensory system development GO:0048880 3 0.010
stem cell proliferation GO:0072089 117 0.010
response to lipopolysaccharide GO:0032496 128 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
male gonad development GO:0008584 88 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
negative regulation of growth GO:0045926 99 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
axonogenesis GO:0007409 274 0.010

Rspo4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
Human
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.010