Mus musculus

0 known processes

Akr1b8

aldo-keto reductase family 1, member B8

(Aliases: FR-1,Fgrp,Fgfrp)

Akr1b8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chemotaxis GO:0006935 247 0.189
cation transport GO:0006812 399 0.167
oxidation reduction process GO:0055114 342 0.150
Human Mouse
cellular amino acid metabolic process GO:0006520 103 0.148
regulation of defense response GO:0031347 233 0.121
negative regulation of cellular protein metabolic process GO:0032269 247 0.118
fibrinolysis GO:0042730 3 0.113
apoptotic signaling pathway GO:0097190 306 0.107
homeostasis of number of cells GO:0048872 210 0.098
cofactor metabolic process GO:0051186 80 0.096
Human
cellular ketone metabolic process GO:0042180 84 0.090
Human
cytokine production GO:0001816 319 0.090
response to molecule of bacterial origin GO:0002237 143 0.089
negative regulation of molecular function GO:0044092 258 0.089
activation of immune response GO:0002253 138 0.086
nucleobase containing small molecule metabolic process GO:0055086 352 0.086
heterocycle catabolic process GO:0046700 280 0.084
myeloid cell differentiation GO:0030099 233 0.078
myeloid cell homeostasis GO:0002262 114 0.077
regulation of mapk cascade GO:0043408 248 0.074
cell type specific apoptotic process GO:0097285 268 0.074
response to oxidative stress GO:0006979 123 0.074
purine containing compound metabolic process GO:0072521 311 0.073
t cell activation GO:0042110 289 0.073
positive regulation of defense response GO:0031349 124 0.073
lipid biosynthetic process GO:0008610 179 0.071
Mouse
organic acid transport GO:0015849 101 0.069
metal ion homeostasis GO:0055065 189 0.067
response to organic cyclic compound GO:0014070 198 0.066
membrane organization GO:0061024 245 0.066
leukocyte homeostasis GO:0001776 79 0.065
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.064
transmembrane transport GO:0055085 412 0.064
extrinsic apoptotic signaling pathway GO:0097191 126 0.062
negative regulation of protein metabolic process GO:0051248 282 0.060
lymphocyte differentiation GO:0030098 242 0.058
regulation of cell motility GO:2000145 236 0.058
nucleoside phosphate metabolic process GO:0006753 338 0.058
positive regulation of programmed cell death GO:0043068 218 0.057
organic anion transport GO:0015711 137 0.057
immune response activating signal transduction GO:0002757 116 0.055
cell adhesion GO:0007155 329 0.054
cellular amine metabolic process GO:0044106 44 0.054
purine ribonucleotide metabolic process GO:0009150 290 0.054
positive regulation of apoptotic process GO:0043065 217 0.054
cell chemotaxis GO:0060326 81 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
positive regulation of cell death GO:0010942 224 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.051
macromolecule catabolic process GO:0009057 281 0.051
extracellular matrix organization GO:0030198 147 0.050
nucleotide metabolic process GO:0009117 332 0.050
cellular response to lipid GO:0071396 145 0.050
regulation of response to wounding GO:1903034 189 0.050
negative regulation of cellular component organization GO:0051129 194 0.049
regulation of organelle organization GO:0033043 289 0.049
regulation of transferase activity GO:0051338 263 0.049
divalent inorganic cation transport GO:0072511 178 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
ribose phosphate metabolic process GO:0019693 291 0.048
cellular response to lipopolysaccharide GO:0071222 77 0.048
inflammatory response GO:0006954 244 0.047
response to inorganic substance GO:0010035 96 0.047
regulation of cell activation GO:0050865 289 0.047
anion transport GO:0006820 177 0.047
regulation of cytokine production GO:0001817 266 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.047
adaptive immune response GO:0002250 155 0.047
purine nucleotide metabolic process GO:0006163 302 0.047
regulation of hydrolase activity GO:0051336 246 0.046
regulation of multi organism process GO:0043900 111 0.046
glycosyl compound catabolic process GO:1901658 206 0.046
i kappab kinase nf kappab signaling GO:0007249 85 0.046
aromatic compound catabolic process GO:0019439 286 0.045
regulation of homeostatic process GO:0032844 182 0.045
t cell receptor signaling pathway GO:0050852 46 0.044
negative regulation of phosphate metabolic process GO:0045936 184 0.044
response to growth factor GO:0070848 198 0.044
protein maturation GO:0051604 176 0.043
negative regulation of immune system process GO:0002683 209 0.043
cellular metal ion homeostasis GO:0006875 151 0.043
response to organonitrogen compound GO:0010243 246 0.042
protein processing GO:0016485 163 0.042
protein catabolic process GO:0030163 221 0.042
response to metal ion GO:0010038 47 0.042
extracellular structure organization GO:0043062 148 0.042
lymphocyte proliferation GO:0046651 164 0.041
innate immune response GO:0045087 157 0.041
cellular response to cadmium ion GO:0071276 3 0.041
regulation of cell adhesion GO:0030155 154 0.040
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.040
positive regulation of eosinophil migration GO:2000418 2 0.040
defense response to other organism GO:0098542 197 0.040
leukocyte differentiation GO:0002521 342 0.039
carboxylic acid transport GO:0046942 100 0.039
regulation of cellular catabolic process GO:0031329 242 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.039
blood vessel morphogenesis GO:0048514 285 0.039
regulation of inflammatory response GO:0050727 147 0.038
negative regulation of cell proliferation GO:0008285 296 0.037
cell recognition GO:0008037 83 0.037
dna metabolic process GO:0006259 303 0.037
glycosyl compound metabolic process GO:1901657 246 0.037
Human
ribonucleoside catabolic process GO:0042454 206 0.037
reactive oxygen species metabolic process GO:0072593 84 0.037
striated muscle tissue development GO:0014706 293 0.037
leukocyte apoptotic process GO:0071887 71 0.036
cellular response to inorganic substance GO:0071241 37 0.036
regulation of ion transport GO:0043269 215 0.036
regulation of neuron differentiation GO:0045664 281 0.036
mapk cascade GO:0000165 281 0.035
wound healing GO:0042060 157 0.035
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.035
small gtpase mediated signal transduction GO:0007264 97 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
thymocyte migration GO:0072679 2 0.034
organonitrogen compound catabolic process GO:1901565 264 0.034
divalent metal ion transport GO:0070838 172 0.033
guanosine containing compound catabolic process GO:1901069 144 0.033
regulation of membrane potential GO:0042391 192 0.033
positive regulation of cell activation GO:0050867 158 0.033
ion transmembrane transport GO:0034220 361 0.033
cellular response to biotic stimulus GO:0071216 92 0.033
negative regulation of phosphorylation GO:0042326 166 0.032
immune response regulating signaling pathway GO:0002764 125 0.032
positive regulation of protein modification process GO:0031401 299 0.032
cation homeostasis GO:0055080 212 0.032
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
regulation of cellular response to stress GO:0080135 159 0.032
ribonucleoside metabolic process GO:0009119 245 0.031
cellularization GO:0007349 1 0.031
negative regulation of protein maturation GO:1903318 79 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
single organism cell adhesion GO:0098602 156 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
t cell differentiation GO:0030217 174 0.031
response to lipopolysaccharide GO:0032496 128 0.031
unsaturated fatty acid metabolic process GO:0033559 31 0.030
integrin mediated signaling pathway GO:0007229 27 0.030
regulation of leukocyte apoptotic process GO:2000106 56 0.030
fatty acid metabolic process GO:0006631 121 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
cellular lipid metabolic process GO:0044255 323 0.030
Human
regulation of secretion by cell GO:1903530 249 0.030
regulation of cell projection organization GO:0031344 206 0.030
positive regulation of homeostatic process GO:0032846 64 0.030
cytokine mediated signaling pathway GO:0019221 115 0.030
angiogenesis GO:0001525 201 0.029
leukocyte mediated immunity GO:0002443 174 0.029
nucleoside metabolic process GO:0009116 246 0.029
small molecule biosynthetic process GO:0044283 132 0.029
peptidyl amino acid modification GO:0018193 336 0.029
cellular response to arsenic containing substance GO:0071243 4 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
wound healing involved in inflammatory response GO:0002246 4 0.028
regulation of cell migration GO:0030334 219 0.028
regulation of t cell activation GO:0050863 170 0.028
ribonucleotide metabolic process GO:0009259 291 0.027
regulation of eosinophil migration GO:2000416 2 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
lymphocyte activation involved in immune response GO:0002285 93 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
epidermis development GO:0008544 187 0.027
regulation of lymphocyte proliferation GO:0050670 117 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
early endosome to late endosome transport GO:0045022 2 0.027
t cell proliferation GO:0042098 120 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
endocytosis GO:0006897 168 0.026
regulation of innate immune response GO:0045088 91 0.026
response to peptide GO:1901652 136 0.026
alpha beta t cell differentiation GO:0046632 69 0.026
cytoplasmic transport GO:0016482 234 0.026
regulation of cytokine secretion GO:0050707 61 0.026
response to acid chemical GO:0001101 111 0.026
regulation of protein transport GO:0051223 163 0.026
exocytosis GO:0006887 121 0.026
carbohydrate metabolic process GO:0005975 230 0.026
cofactor catabolic process GO:0051187 6 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
jnk cascade GO:0007254 72 0.025
amine metabolic process GO:0009308 45 0.025
leukocyte migration GO:0050900 124 0.025
antigen receptor mediated signaling pathway GO:0050851 64 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.025
monocarboxylic acid transport GO:0015718 44 0.025
neutrophil migration GO:1990266 37 0.025
regulation of endopeptidase activity GO:0052548 89 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
cell activation involved in immune response GO:0002263 126 0.025
nitrogen compound transport GO:0071705 271 0.024
skeletal muscle organ development GO:0060538 163 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
nucleoside catabolic process GO:0009164 206 0.024
gland development GO:0048732 330 0.024
positive regulation of cellular catabolic process GO:0031331 148 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
ras protein signal transduction GO:0007265 77 0.024
plasma membrane organization GO:0007009 90 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
lipid transport GO:0006869 98 0.024
cellular chemical homeostasis GO:0055082 215 0.024
positive regulation of proteolysis GO:0045862 85 0.024
response to radiation GO:0009314 165 0.024
regulation of protein localization GO:0032880 231 0.023
response to peptide hormone GO:0043434 127 0.023
regulation of proteolysis GO:0030162 164 0.023
regulation of protein processing GO:0070613 96 0.023
regulation of protein kinase activity GO:0045859 232 0.023
positive regulation of response to wounding GO:1903036 66 0.023
male gamete generation GO:0048232 285 0.023
response to oxygen levels GO:0070482 62 0.023
t cell extravasation GO:0072683 4 0.023
regulation of neuron projection development GO:0010975 169 0.023
sensory perception GO:0007600 245 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.022
regulation of cell cycle GO:0051726 281 0.022
forebrain development GO:0030900 302 0.022
negative regulation of multi organism process GO:0043901 68 0.022
spermatogenesis GO:0007283 284 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
defense response to bacterium GO:0042742 119 0.022
muscle tissue development GO:0060537 308 0.022
negative regulation of protein modification process GO:0031400 163 0.022
regulation of vesicle mediated transport GO:0060627 139 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
tumor necrosis factor production GO:0032640 50 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.022
lymphocyte apoptotic process GO:0070227 54 0.022
engulfment of apoptotic cell GO:0043652 3 0.022
calcium ion transport GO:0006816 159 0.022
alpha beta t cell activation GO:0046631 91 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
sequestering of metal ion GO:0051238 19 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
wnt signaling pathway GO:0016055 188 0.021
negative regulation of lymphocyte activation GO:0051250 91 0.021
actin cytoskeleton organization GO:0030036 220 0.021
axonogenesis GO:0007409 274 0.021
nucleotide catabolic process GO:0009166 217 0.021
regulation of peptidase activity GO:0052547 96 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
icosanoid metabolic process GO:0006690 33 0.021
organelle localization GO:0051640 179 0.020
regulation of t cell proliferation GO:0042129 92 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
signal transduction in absence of ligand GO:0038034 55 0.020
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.020
cellular response to oxidative stress GO:0034599 76 0.020
response to insulin GO:0032868 100 0.020
leukocyte proliferation GO:0070661 172 0.020
inflammatory response to wounding GO:0090594 4 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
peptide metabolic process GO:0006518 46 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
Human
regulation of lymphocyte activation GO:0051249 240 0.020
positive regulation of lymphocyte activation GO:0051251 140 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
intracellular receptor signaling pathway GO:0030522 74 0.020
leukocyte activation involved in immune response GO:0002366 126 0.020
endomembrane system organization GO:0010256 147 0.020
positive regulation of innate immune response GO:0045089 80 0.020
regulation of integrin mediated signaling pathway GO:2001044 8 0.020
regulation of protein maturation GO:1903317 96 0.020
immune effector process GO:0002252 321 0.020
fatty acid derivative metabolic process GO:1901568 33 0.020
organophosphate catabolic process GO:0046434 232 0.019
response to light stimulus GO:0009416 135 0.019
positive regulation of t cell activation GO:0050870 101 0.019
negative regulation of cell cycle GO:0045786 123 0.019
synaptic transmission GO:0007268 329 0.019
skeletal system development GO:0001501 356 0.019
muscle cell development GO:0055001 133 0.019
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.019
action potential GO:0001508 78 0.019
cellular homeostasis GO:0019725 240 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
cytokine secretion GO:0050663 72 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
regulation of kinase activity GO:0043549 249 0.019
regulation of stress activated mapk cascade GO:0032872 69 0.019
regulation of protein catabolic process GO:0042176 108 0.019
cellular ion homeostasis GO:0006873 165 0.019
regulation of lymphocyte apoptotic process GO:0070228 41 0.019
sequestering of calcium ion GO:0051208 18 0.019
purine containing compound catabolic process GO:0072523 213 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.019
intracellular protein transport GO:0006886 204 0.019
eosinophil migration GO:0072677 3 0.019
skin development GO:0043588 220 0.019
response to steroid hormone GO:0048545 56 0.019
cell substrate adhesion GO:0031589 130 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
organic hydroxy compound biosynthetic process GO:1901617 77 0.019
regulation of vasculature development GO:1901342 88 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
cellular amide metabolic process GO:0043603 58 0.018
regulation of actin filament based process GO:0032970 99 0.018
ameboidal type cell migration GO:0001667 128 0.018
positive regulation of phospholipase activity GO:0010518 3 0.018
negative regulation of transferase activity GO:0051348 85 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
cation transmembrane transport GO:0098655 266 0.018
b cell activation GO:0042113 161 0.018
nuclear transport GO:0051169 139 0.018
negative regulation of kinase activity GO:0033673 81 0.018
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.017
response to transforming growth factor beta GO:0071559 88 0.017
germ cell development GO:0007281 185 0.017
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.017
multicellular organismal signaling GO:0035637 91 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.017
neuron death GO:0070997 154 0.017
circulatory system process GO:0003013 197 0.017
glycoprotein metabolic process GO:0009100 116 0.017
regulation of thymocyte migration GO:2000410 2 0.017
regulation of secretion GO:0051046 274 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
phagocytosis GO:0006909 66 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
response to decreased oxygen levels GO:0036293 59 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
negative regulation of reproductive process GO:2000242 31 0.017
cellular response to acid chemical GO:0071229 68 0.017
organic acid biosynthetic process GO:0016053 86 0.017
interferon gamma production GO:0032609 67 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
gtp metabolic process GO:0046039 144 0.016
positive regulation of organelle organization GO:0010638 128 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
regulation of binding GO:0051098 111 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
regulation of cellular component size GO:0032535 121 0.016
immunoglobulin production GO:0002377 73 0.016
positive regulation of leukocyte mediated immunity GO:0002705 70 0.016
response to temperature stimulus GO:0009266 55 0.016
regulation of protein secretion GO:0050708 82 0.016
negative regulation of cell activation GO:0050866 111 0.016
negative regulation of cytokine production GO:0001818 84 0.016
substantia nigra development GO:0021762 2 0.016
negative regulation of hydrolase activity GO:0051346 71 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
fatty acid transport GO:0015908 28 0.016
calcium ion homeostasis GO:0055074 127 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
antimicrobial peptide biosynthetic process GO:0002777 2 0.016
porphyrin containing compound metabolic process GO:0006778 22 0.015
tissue homeostasis GO:0001894 115 0.015
alcohol metabolic process GO:0006066 116 0.015
Human
glutathione metabolic process GO:0006749 16 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
mitochondrion distribution GO:0048311 4 0.015
multi multicellular organism process GO:0044706 109 0.015
gonad development GO:0008406 141 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.015
negative regulation of protein processing GO:0010955 79 0.015
negative regulation of b cell proliferation GO:0030889 13 0.015
glial cell differentiation GO:0010001 131 0.015
response to extracellular stimulus GO:0009991 127 0.015
positive regulation of nervous system development GO:0051962 221 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
myotube differentiation GO:0014902 105 0.015
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.015
organophosphate biosynthetic process GO:0090407 122 0.014
pigment metabolic process GO:0042440 32 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of reproductive process GO:2000241 66 0.014
positive regulation of cytokine production GO:0001819 174 0.014
development of primary sexual characteristics GO:0045137 143 0.014
lymphocyte homeostasis GO:0002260 64 0.014
negative regulation of proteolysis GO:0045861 74 0.014
neuronal action potential GO:0019228 54 0.014
axon guidance GO:0007411 141 0.014
ossification GO:0001503 216 0.014
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.014
blood circulation GO:0008015 195 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
negative regulation of cell migration GO:0030336 59 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
anatomical structure homeostasis GO:0060249 145 0.014
transmission of nerve impulse GO:0019226 76 0.014
regulation of protein complex assembly GO:0043254 83 0.014
membrane fusion GO:0061025 38 0.014
striated muscle cell development GO:0055002 125 0.014
mitotic cell cycle process GO:1903047 159 0.013
antimicrobial peptide production GO:0002775 2 0.013
b cell chemotaxis GO:0035754 3 0.013
cellular response to metal ion GO:0071248 31 0.013
response to hypoxia GO:0001666 58 0.013
regulation of anatomical structure size GO:0090066 178 0.013
lipid localization GO:0010876 126 0.013
compound eye development GO:0048749 1 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
positive regulation of inflammatory response GO:0050729 47 0.013
protein oligomerization GO:0051259 67 0.013
protein localization to organelle GO:0033365 185 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
leukocyte chemotaxis GO:0030595 69 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
positive regulation of monocyte chemotaxis GO:0090026 2 0.013
monosaccharide metabolic process GO:0005996 106 0.013
protein secretion GO:0009306 111 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
positive regulation of necrotic cell death GO:0010940 1 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
spleen development GO:0048536 39 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
regulation of neuron death GO:1901214 134 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of intracellular transport GO:0032386 159 0.013
dendrite development GO:0016358 115 0.013
nuclear division GO:0000280 158 0.013
developmental maturation GO:0021700 193 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
regulation of system process GO:0044057 200 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
myoblast differentiation GO:0045445 52 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of transmembrane transport GO:0034762 128 0.013
cytokinetic process GO:0032506 2 0.012
negative regulation of leukocyte proliferation GO:0070664 46 0.012
b cell activation involved in immune response GO:0002312 50 0.012
regulation of exocytosis GO:0017157 61 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
fatty acid biosynthetic process GO:0006633 41 0.012
sulfur compound metabolic process GO:0006790 100 0.012
regulation of interleukin 1 alpha production GO:0032650 4 0.012
antibacterial peptide secretion GO:0002779 1 0.012
positive regulation of immune effector process GO:0002699 107 0.012
interleukin 8 production GO:0032637 4 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
microtubule based process GO:0007017 236 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
negative regulation of cell motility GO:2000146 61 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
regulation of erk1 and erk2 cascade GO:0070372 71 0.012
positive regulation of cell motility GO:2000147 116 0.012
regulation of acute inflammatory response GO:0002673 27 0.012
protein targeting GO:0006605 143 0.012
maintenance of location GO:0051235 89 0.012
lateral inhibition GO:0046331 1 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
regulation of cytokine secretion involved in immune response GO:0002739 4 0.012
interleukin 12 secretion GO:0072610 3 0.012
organelle fission GO:0048285 170 0.012
regulation of myotube differentiation GO:0010830 62 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
circadian rhythm GO:0007623 114 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
translation GO:0006412 93 0.011
localization within membrane GO:0051668 4 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
muscle fiber development GO:0048747 76 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
long chain fatty acid transport GO:0015909 15 0.011
placenta development GO:0001890 140 0.011
myelination GO:0042552 74 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
fertilization GO:0009566 127 0.011
muscle cell differentiation GO:0042692 261 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
positive regulation of lymphocyte differentiation GO:0045621 61 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011

Akr1b8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.017
neuropathy DOID:870 0 0.012
charcot marie tooth disease DOID:10595 0 0.012
neuromuscular disease DOID:440 0 0.012