Mus musculus

243 known processes

Bmpr1a

bone morphogenetic protein receptor, type 1A

(Aliases: Bmpr,1110037I22Rik,AU045487,ALK3,BMPR-IA)

Bmpr1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to sterol GO:0036314 4 0.999
Mouse
germ line stem cell division GO:0042078 2 0.999
Fly
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.996
lateral mesodermal cell differentiation GO:0048371 3 0.994
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.994
Mouse
chondrocyte development GO:0002063 24 0.991
Mouse
formation of radial glial scaffolds GO:0021943 4 0.990
regionalization GO:0003002 337 0.987
metanephric mesenchyme morphogenesis GO:0072133 4 0.985
digestive tract morphogenesis GO:0048546 147 0.979
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.978
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.977
mesenchyme development GO:0060485 152 0.976
embryonic skeletal system development GO:0048706 120 0.974
Mouse
embryonic organ morphogenesis GO:0048562 276 0.974
Zebrafish Mouse
response to growth factor GO:0070848 198 0.974
Mouse Fly
kidney mesenchyme morphogenesis GO:0072131 4 0.971
regulation of cell migration GO:0030334 219 0.971
Mouse
camera type eye development GO:0043010 266 0.969
Mouse
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.968
blood vessel morphogenesis GO:0048514 285 0.967
Mouse
cell proliferation involved in heart valve morphogenesis GO:0003249 1 0.966
positive regulation of cell projection organization GO:0031346 95 0.966
Mouse
hair follicle development GO:0001942 85 0.965
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.959
Mouse
mesenchymal cell differentiation GO:0048762 107 0.952
ossification GO:0001503 216 0.951
Human
mesendoderm development GO:0048382 3 0.946
striated muscle tissue development GO:0014706 293 0.945
organ growth GO:0035265 117 0.944
Mouse Fly
digestive tract development GO:0048565 190 0.943
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.942
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.940
ventricular septum morphogenesis GO:0060412 27 0.935
mesenchyme morphogenesis GO:0072132 32 0.927
wnt signaling pathway GO:0016055 188 0.926
clara cell differentiation GO:0060486 4 0.922
lens development in camera type eye GO:0002088 62 0.920
Mouse
cardiac endothelial cell differentiation GO:0003348 4 0.915
bronchus morphogenesis GO:0060434 2 0.915
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.911
Mouse
muscle tissue development GO:0060537 308 0.898
skeletal system development GO:0001501 356 0.897
digestive system development GO:0055123 200 0.897
cell migration involved in gastrulation GO:0042074 13 0.896
negative regulation of bmp signaling pathway GO:0030514 35 0.891
inner ear receptor cell differentiation GO:0060113 61 0.890
paraxial mesoderm structural organization GO:0048352 1 0.884
blastoderm segmentation GO:0007350 13 0.884
organelle localization GO:0051640 179 0.884
endodermal cell fate commitment GO:0001711 12 0.884
Fly
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.882
Fly
engulfment of apoptotic cell GO:0043652 3 0.882
stem cell development GO:0048864 219 0.880
blood circulation GO:0008015 195 0.879
Mouse
circulatory system process GO:0003013 197 0.876
Mouse
lateral mesodermal cell fate commitment GO:0048372 2 0.874
regulation of wnt signaling pathway GO:0030111 123 0.866
leukocyte differentiation GO:0002521 342 0.866
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.861
endocardial cushion formation GO:0003272 13 0.855
positive regulation of apoptotic signaling pathway GO:2001235 95 0.851
Mouse
regulation of organ morphogenesis GO:2000027 144 0.851
limb morphogenesis GO:0035108 149 0.843
paraxial mesoderm morphogenesis GO:0048340 10 0.842
oocyte axis specification GO:0007309 2 0.839
regulation of cell adhesion GO:0030155 154 0.839
Worm Fly
cardiac muscle tissue development GO:0048738 130 0.831
stem cell division GO:0017145 30 0.826
Fly
chondrocyte differentiation GO:0002062 72 0.825
Mouse
segmentation GO:0035282 93 0.824
regulation of canonical wnt signaling pathway GO:0060828 82 0.824
hindbrain radial glia guided cell migration GO:0021932 12 0.817
mesonephric tubule development GO:0072164 94 0.815
regulation of intracellular protein transport GO:0033157 82 0.814
Human
epidermis development GO:0008544 187 0.809
Mouse
endocardial cushion morphogenesis GO:0003203 18 0.803
positive regulation of bmp signaling pathway GO:0030513 23 0.801
Mouse
venous blood vessel development GO:0060841 13 0.795
Mouse
mesoderm development GO:0007498 100 0.793
cardiac septum morphogenesis GO:0060411 46 0.790
germ cell development GO:0007281 185 0.787
Mouse Fly
cell adhesion GO:0007155 329 0.787
Worm Fly
retina vasculature development in camera type eye GO:0061298 17 0.782
Mouse
striated muscle cell development GO:0055002 125 0.782
single organismal cell cell adhesion GO:0016337 131 0.776
Fly
regulation of neuron projection development GO:0010975 169 0.775
Mouse
single organism cell adhesion GO:0098602 156 0.772
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.768
Mouse
cardiac chamber development GO:0003205 108 0.767
cartilage development GO:0051216 140 0.765
connective tissue development GO:0061448 179 0.762
pole plasm assembly GO:0007315 2 0.761
myeloid cell differentiation GO:0030099 233 0.761
Mouse
regulation of mapk cascade GO:0043408 248 0.760
mapk cascade GO:0000165 281 0.756
angiogenesis GO:0001525 201 0.755
Mouse
appendage development GO:0048736 166 0.754
skeletal system morphogenesis GO:0048705 203 0.752
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.751
Mouse
neural plate mediolateral regionalization GO:0021998 1 0.747
palate development GO:0060021 76 0.747
maternal process involved in female pregnancy GO:0060135 32 0.745
Mouse
endodermal cell fate specification GO:0001714 4 0.743
Fly
urogenital system development GO:0001655 261 0.732
Mouse Fly
osteoblast development GO:0002076 17 0.732
artery development GO:0060840 53 0.730
Mouse
epithelial tube morphogenesis GO:0060562 303 0.730
Zebrafish Mouse
stem cell differentiation GO:0048863 268 0.730
muscle cell differentiation GO:0042692 261 0.729
Mouse
membrane organization GO:0061024 245 0.728
smoothened signaling pathway GO:0007224 105 0.727
Mouse
regulation of cartilage development GO:0061035 44 0.727
Mouse
paraxial mesoderm development GO:0048339 18 0.727
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.726
Mouse Fly
regulation of cell proliferation involved in heart valve morphogenesis GO:0003250 1 0.725
endocardial cell differentiation GO:0060956 4 0.725
cardiac ventricle development GO:0003231 83 0.722
renal system development GO:0072001 225 0.721
Mouse Fly
endothelial cell activation GO:0042118 1 0.713
cardiac septum development GO:0003279 59 0.712
neural tube development GO:0021915 160 0.711
heart morphogenesis GO:0003007 178 0.707
regulation of protein kinase activity GO:0045859 232 0.703
Mouse
telencephalon development GO:0021537 186 0.701
cell fate commitment GO:0045165 210 0.701
response to cholesterol GO:0070723 4 0.697
Mouse
pallium development GO:0021543 120 0.696
regulation of cell motility GO:2000145 236 0.694
Mouse
regulation of smad protein import into nucleus GO:0060390 3 0.693
Human
regulation of neuron differentiation GO:0045664 281 0.693
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.692
Human
cardiocyte differentiation GO:0035051 87 0.692
heart valve development GO:0003170 23 0.689
ureteric bud morphogenesis GO:0060675 62 0.686
asymmetric neuroblast division GO:0055059 1 0.684
regulation of intracellular transport GO:0032386 159 0.681
Human
morphogenesis of a branching epithelium GO:0061138 193 0.681
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.680
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.680
positive regulation of cell development GO:0010720 237 0.680
Mouse
kidney development GO:0001822 213 0.677
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.675
gastrulation with mouth forming second GO:0001702 29 0.674
Mouse
schwann cell proliferation GO:0014010 2 0.673
mesoderm formation GO:0001707 62 0.671
mesonephric epithelium development GO:0072163 94 0.664
peptidyl threonine phosphorylation GO:0018107 31 0.656
Mouse
epithelial cell proliferation GO:0050673 174 0.655
gastrulation GO:0007369 116 0.653
positive regulation of leukocyte differentiation GO:1902107 86 0.645
Mouse
oocyte construction GO:0007308 2 0.644
endochondral bone growth GO:0003416 19 0.644
Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.644
fused antrum stage GO:0048165 1 0.638
Mouse
regulation of tolerance induction to self antigen GO:0002649 1 0.637
Mouse
appendage morphogenesis GO:0035107 149 0.637
heart field specification GO:0003128 6 0.635
gland development GO:0048732 330 0.632
regulation of hormone secretion GO:0046883 88 0.629
Mouse
limb development GO:0060173 166 0.627
endochondral bone morphogenesis GO:0060350 50 0.626
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.625
somitogenesis GO:0001756 69 0.625
dna metabolic process GO:0006259 303 0.624
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.623
Mouse
negative regulation of peptidyl threonine phosphorylation GO:0010801 6 0.621
bmp signaling pathway GO:0030509 93 0.614
heart valve morphogenesis GO:0003179 21 0.612
regulation of transferase activity GO:0051338 263 0.611
Mouse
cytoplasmic transport GO:0016482 234 0.611
Human
regulation of defense response GO:0031347 233 0.609
positive regulation of smad protein import into nucleus GO:0060391 2 0.609
Human
lateral mesoderm formation GO:0048370 3 0.605
anterior posterior axis specification embryo GO:0008595 9 0.602
neural tube closure GO:0001843 90 0.602
endocardial cushion development GO:0003197 26 0.601
gonad development GO:0008406 141 0.600
Mouse
hair cycle GO:0042633 90 0.596
Mouse
regulation of protein transport GO:0051223 163 0.596
Human
regulation of ossification GO:0030278 112 0.590
Human
regulation of protein targeting GO:1903533 61 0.586
Human
bone development GO:0060348 120 0.585
Mouse
positive regulation of osteoblast differentiation GO:0045669 34 0.584
Human
nitrogen compound transport GO:0071705 271 0.583
Mouse
regulation of chemotaxis GO:0050920 53 0.580
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.579
Mouse
oocyte anterior posterior axis specification GO:0007314 2 0.579
nephron tubule morphogenesis GO:0072078 68 0.576
endoderm development GO:0007492 45 0.575
regulation of apoptotic signaling pathway GO:2001233 197 0.574
Mouse
negative regulation of immune system process GO:0002683 209 0.573
mitotic cell cycle GO:0000278 195 0.570
retina development in camera type eye GO:0060041 119 0.570
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.570
Mouse Fly
axon guidance GO:0007411 141 0.569
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.569
regulation of t cell differentiation GO:0045580 83 0.567
Mouse
cell proliferation involved in heart valve development GO:2000793 2 0.567
multicellular organism growth GO:0035264 161 0.564
Worm
cell cycle switching GO:0060184 1 0.562
protein localization to nucleus GO:0034504 121 0.562
Human Worm
embryonic heart tube morphogenesis GO:0003143 51 0.559
Zebrafish
forebrain development GO:0030900 302 0.557
positive regulation of cell motility GO:2000147 116 0.556
Mouse
ventricular septum development GO:0003281 42 0.555
ameboidal type cell migration GO:0001667 128 0.553
Mouse
olfactory learning GO:0008355 2 0.549
mesenchymal cell development GO:0014031 93 0.548
negative regulation of cell motility GO:2000146 61 0.546
outflow tract morphogenesis GO:0003151 53 0.546
regulation of protein import into nucleus GO:0042306 52 0.546
Human
male sex differentiation GO:0046661 109 0.546
membrane invagination GO:0010324 17 0.545
stem cell maintenance GO:0019827 130 0.540
regulation of hair follicle development GO:0051797 9 0.539
negative regulation of defense response GO:0031348 77 0.539
mesodermal cell migration GO:0008078 4 0.533
negative regulation of cell development GO:0010721 169 0.531
regulation of cellular response to growth factor stimulus GO:0090287 82 0.531
lymphocyte differentiation GO:0030098 242 0.528
Mouse
chondrocyte hypertrophy GO:0003415 4 0.525
Mouse
regulation of binding GO:0051098 111 0.522
Mouse
positive regulation of t cell tolerance induction GO:0002666 6 0.520
Mouse
neuron projection guidance GO:0097485 141 0.520
Mouse
thymus development GO:0048538 41 0.519
Mouse
synapse organization GO:0050808 125 0.517
Fly
regulation of mesoderm development GO:2000380 12 0.515
regulation of mesodermal cell fate specification GO:0042661 5 0.514
cell substrate adhesion GO:0031589 130 0.514
cell division GO:0051301 120 0.513
Fly
nephron epithelium morphogenesis GO:0072088 68 0.512
neural crest cell development GO:0014032 48 0.512
establishment of organelle localization GO:0051656 122 0.511
cartilage condensation GO:0001502 18 0.510
Mouse
hindlimb morphogenesis GO:0035137 42 0.507
positive regulation of dendrite development GO:1900006 21 0.506
regulation of cell projection organization GO:0031344 206 0.506
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.505
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.504
defense response to other organism GO:0098542 197 0.498
Worm
innate immune response GO:0045087 157 0.497
Worm
cerebral cortex development GO:0021987 86 0.496
determination of left right symmetry GO:0007368 80 0.495
Zebrafish Mouse
mesodermal cell fate specification GO:0007501 11 0.494
establishment or maintenance of cell polarity GO:0007163 86 0.494
protein localization to organelle GO:0033365 185 0.493
Human Worm
regulation of vasculature development GO:1901342 88 0.491
Mouse
maternal placenta development GO:0001893 20 0.486
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.479
mesodermal cell fate commitment GO:0001710 17 0.478
negative regulation of t cell proliferation GO:0042130 38 0.477
respiratory tube development GO:0030323 167 0.476
positive regulation of programmed cell death GO:0043068 218 0.473
Mouse
kidney morphogenesis GO:0060993 83 0.473
peptide transport GO:0015833 133 0.472
Mouse
peptidyl threonine modification GO:0018210 31 0.471
Mouse
placenta development GO:0001890 140 0.471
Mouse
proteoglycan metabolic process GO:0006029 38 0.470
regulation of dna replication GO:0006275 17 0.464
lung induction GO:0060492 3 0.464
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.462
macromolecule catabolic process GO:0009057 281 0.459
Worm
skin development GO:0043588 220 0.457
Mouse
atrial septum primum morphogenesis GO:0003289 3 0.456
lateral mesoderm development GO:0048368 13 0.455
mitral valve morphogenesis GO:0003183 4 0.453
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.453
negative regulation of ossification GO:0030279 49 0.452
endocrine system development GO:0035270 98 0.449
regulation of cell cycle GO:0051726 281 0.449
mesodermal cell differentiation GO:0048333 22 0.445
axis elongation involved in somitogenesis GO:0090245 4 0.443
forebrain generation of neurons GO:0021872 63 0.443
apoptotic signaling pathway GO:0097190 306 0.442
Mouse
nephron tubule development GO:0072080 84 0.441
neural tube formation GO:0001841 108 0.441
osteoblast fate commitment GO:0002051 4 0.441
negative regulation of protein phosphorylation GO:0001933 126 0.439
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.439
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.438
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.436
cardiac epithelial to mesenchymal transition GO:0060317 18 0.433
atrioventricular valve morphogenesis GO:0003181 13 0.432
smad protein complex assembly GO:0007183 1 0.430
endothelial cell fate commitment GO:0060839 2 0.430
nk t cell differentiation GO:0001865 8 0.429
Mouse
positive regulation of wnt signaling pathway GO:0030177 45 0.427
neural crest cell differentiation GO:0014033 54 0.426
cardiac muscle cell development GO:0055013 39 0.423
negative regulation of mitotic cell cycle GO:0045930 58 0.422
response to alcohol GO:0097305 48 0.422
Mouse
renal tubule development GO:0061326 87 0.421
Fly
regulation of leukocyte differentiation GO:1902105 159 0.420
Mouse
epidermis morphogenesis GO:0048730 33 0.420
actin cytoskeleton organization GO:0030036 220 0.418
peptidyl tyrosine phosphorylation GO:0018108 143 0.418
negative regulation of nervous system development GO:0051961 156 0.417
regulation of transforming growth factor beta2 production GO:0032909 2 0.417
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.414
axonogenesis GO:0007409 274 0.413
Mouse
central nervous system neuron differentiation GO:0021953 162 0.410
polarity specification of proximal distal axis GO:0010085 2 0.410
maternal determination of anterior posterior axis embryo GO:0008358 2 0.410
regulation of stem cell proliferation GO:0072091 78 0.403
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.401
Mouse
mesoderm morphogenesis GO:0048332 64 0.399
dna replication GO:0006260 52 0.397
growth plate cartilage development GO:0003417 14 0.394
Mouse
embryonic placenta development GO:0001892 98 0.394
protein catabolic process GO:0030163 221 0.394
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.393
positive regulation of neuron projection development GO:0010976 79 0.392
Mouse
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.391
regulation of cytoplasmic transport GO:1903649 112 0.391
Human
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.390
positive regulation of cell migration GO:0030335 109 0.389
Mouse
ureteric bud development GO:0001657 94 0.387
pituitary gland development GO:0021983 38 0.385
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.383
pharynx development GO:0060465 1 0.381
skeletal muscle organ development GO:0060538 163 0.381
myelination in peripheral nervous system GO:0022011 19 0.381
negative regulation of osteoblast differentiation GO:0045668 30 0.379
negative regulation of glial cell proliferation GO:0060253 4 0.377
positive regulation of apoptotic process GO:0043065 217 0.377
Mouse
positive regulation of glial cell proliferation GO:0060252 4 0.375
cellular response to glucocorticoid stimulus GO:0071385 13 0.375
alpha beta t cell differentiation GO:0046632 69 0.375
Mouse
insulin secretion GO:0030073 89 0.372
Mouse
lateral mesodermal cell fate specification GO:0048377 2 0.372
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.371
embryonic epithelial tube formation GO:0001838 130 0.371
regulation of blood pressure GO:0008217 93 0.369
Mouse
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.368
kidney epithelium development GO:0072073 121 0.368
spermatid differentiation GO:0048515 115 0.367
olfactory lobe development GO:0021988 32 0.366
cell type specific apoptotic process GO:0097285 268 0.365
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.361
mitochondrion distribution GO:0048311 4 0.359
mesoderm structural organization GO:0048338 1 0.358
lateral mesoderm morphogenesis GO:0048369 3 0.357
amine metabolic process GO:0009308 45 0.356
molting cycle GO:0042303 90 0.355
Mouse
positive regulation of cell adhesion GO:0045785 80 0.354
canonical wnt signaling pathway GO:0060070 130 0.351
tripartite regional subdivision GO:0007351 9 0.351
cardiac muscle cell proliferation GO:0060038 31 0.351
positive regulation of determination of dorsal identity GO:2000017 2 0.350
peptidyl amino acid modification GO:0018193 336 0.349
Mouse
heart contraction GO:0060047 93 0.349
antral ovarian follicle growth GO:0001547 5 0.348
Mouse
nephron morphogenesis GO:0072028 69 0.348
blastocyst development GO:0001824 80 0.346
Mouse
central nervous system vasculogenesis GO:0022009 3 0.345
growth plate cartilage chondrocyte development GO:0003431 3 0.344
Mouse
secondary heart field specification GO:0003139 6 0.344
cardiac muscle cell differentiation GO:0055007 69 0.343
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.343
dendrite development GO:0016358 115 0.342
primary neural tube formation GO:0014020 95 0.338
midbrain development GO:0030901 35 0.335
regulation of protein localization GO:0032880 231 0.334
Human
neuroblast division in subventricular zone GO:0021849 2 0.334
hindbrain development GO:0030902 128 0.333
negative regulation of phosphorylation GO:0042326 166 0.333
trachea formation GO:0060440 3 0.330
Mouse
negative regulation of osteoblast proliferation GO:0033689 4 0.330
amide transport GO:0042886 138 0.330
Mouse
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation GO:0061324 2 0.329
forebrain neuron differentiation GO:0021879 52 0.329
bone morphogenesis GO:0060349 78 0.328
Mouse
regulation of system process GO:0044057 200 0.327
Mouse
cytokine production GO:0001816 319 0.327
t cell activation GO:0042110 289 0.326
Mouse
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.324
negative regulation of cell proliferation GO:0008285 296 0.321
Mouse
intracellular protein transport GO:0006886 204 0.320
Human
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.318
regulation of protein stability GO:0031647 52 0.318
mesonephric tubule morphogenesis GO:0072171 63 0.318
atrioventricular valve formation GO:0003190 5 0.317
positive regulation of transferase activity GO:0051347 167 0.314
Mouse
embryonic axis specification GO:0000578 30 0.314
jnk cascade GO:0007254 72 0.314
regulation of myeloid leukocyte differentiation GO:0002761 58 0.313
positive regulation of b cell tolerance induction GO:0002663 2 0.312
Mouse
developmental cell growth GO:0048588 84 0.311
Mouse
response to transforming growth factor beta GO:0071559 88 0.311
Mouse Fly
regulation of cytokine production GO:0001817 266 0.310
morphogenesis of a branching structure GO:0001763 203 0.310
Mouse
sensory organ morphogenesis GO:0090596 242 0.309
Fly
positive regulation of chemotaxis GO:0050921 38 0.308
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.304
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.303
regulation of kinase activity GO:0043549 249 0.302
Mouse
positive regulation of protein modification process GO:0031401 299 0.300
Human Mouse
nephrogenic mesenchyme development GO:0072076 3 0.300
lung lobe morphogenesis GO:0060463 9 0.300
Mouse
lipid localization GO:0010876 126 0.299
Mouse
embryonic digit morphogenesis GO:0042733 56 0.297
lung development GO:0030324 164 0.297
regulation of blood circulation GO:1903522 93 0.296
Mouse
apical junction assembly GO:0043297 15 0.296
regulation of myeloid cell differentiation GO:0045637 96 0.293
positive regulation of intracellular transport GO:0032388 70 0.292
Human
pathway restricted smad protein phosphorylation GO:0060389 10 0.292
Human
negative regulation of anti mullerian hormone signaling pathway GO:1902613 1 0.290
Mouse
regulation of feeding behavior GO:0060259 3 0.290
positive regulation of map kinase activity GO:0043406 84 0.288
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.285
Mouse Fly
negative regulation of organ growth GO:0046621 17 0.285
regulation of lymphocyte proliferation GO:0050670 117 0.285
positive regulation of cardioblast differentiation GO:0051891 3 0.285
intracellular mrna localization GO:0008298 4 0.284
regulation of secretion by cell GO:1903530 249 0.283
Mouse
positive regulation of binding GO:0051099 49 0.283
diencephalon development GO:0021536 63 0.282
positive regulation of cell activation GO:0050867 158 0.282
Mouse
metencephalon development GO:0022037 89 0.282
striated muscle cell proliferation GO:0014855 39 0.281
regulation of innate immune response GO:0045088 91 0.279
myeloid dendritic cell activation GO:0001773 25 0.279
Mouse
hair follicle morphogenesis GO:0031069 29 0.278
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.277
Mouse
negative regulation of protein modification process GO:0031400 163 0.276
cell proliferation in hindbrain GO:0021534 10 0.275
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.275
negative regulation of cellular amine metabolic process GO:0033239 1 0.275
nucleoside phosphate metabolic process GO:0006753 338 0.275
cellular response to dna damage stimulus GO:0006974 207 0.275
hair follicle cell proliferation GO:0071335 3 0.274
regulation of tolerance induction GO:0002643 10 0.274
Mouse
rho protein signal transduction GO:0007266 32 0.273
synaptic growth at neuromuscular junction GO:0051124 6 0.271
Fly
respiratory system development GO:0060541 190 0.269
regulation of cell projection assembly GO:0060491 38 0.266
Mouse
regulation of organ growth GO:0046620 61 0.266
Fly
development of primary male sexual characteristics GO:0046546 88 0.265
Mouse
macrophage differentiation GO:0030225 20 0.264
mammary gland morphogenesis GO:0060443 54 0.264
Mouse
cardiac cell development GO:0055006 41 0.264
regulation of muscle tissue development GO:1901861 97 0.263
regulation of cellular amine metabolic process GO:0033238 20 0.263
epithelial to mesenchymal transition GO:0001837 47 0.262
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.261
regulation of t cell activation GO:0050863 170 0.259
Mouse
lipid storage GO:0019915 36 0.259
Mouse
cardiac conduction system development GO:0003161 12 0.258
response to organic cyclic compound GO:0014070 198 0.258
Mouse
neural crest cell migration GO:0001755 32 0.257
Mouse
epithelium migration GO:0090132 63 0.255
Mouse
mechanoreceptor differentiation GO:0042490 67 0.254
proteoglycan biosynthetic process GO:0030166 20 0.254
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.254
regulation of cellular component biogenesis GO:0044087 181 0.253
Mouse Fly
cell matrix adhesion GO:0007160 68 0.252
regulation of cardiac muscle tissue development GO:0055024 31 0.252
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.251
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.251
embryonic limb morphogenesis GO:0030326 126 0.251
regulation of determination of dorsal identity GO:2000015 3 0.248
tissue migration GO:0090130 68 0.246
Mouse
olfactory bulb development GO:0021772 30 0.246
b cell tolerance induction GO:0002514 2 0.246
Mouse
muscle cell development GO:0055001 133 0.246
neuron apoptotic process GO:0051402 142 0.246
mitral valve development GO:0003174 4 0.246
dorsal ventral axon guidance GO:0033563 3 0.245
pigmentation GO:0043473 71 0.244
morphogenesis of embryonic epithelium GO:0016331 159 0.244
Fly
single organism nuclear import GO:1902593 95 0.243
Human
chemotaxis GO:0006935 247 0.241
Mouse
peptidyl serine modification GO:0018209 83 0.240
positive regulation of protein phosphorylation GO:0001934 242 0.239
Human Mouse
negative regulation of gliogenesis GO:0014014 23 0.239
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.238
oocyte differentiation GO:0009994 35 0.238
neuron projection extension GO:1990138 64 0.238
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.238
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.234
non canonical wnt signaling pathway GO:0035567 33 0.233
g1 s transition of mitotic cell cycle GO:0000082 57 0.232
nephron development GO:0072006 109 0.229
regulation of cardiac muscle cell proliferation GO:0060043 23 0.229
salivary gland morphogenesis GO:0007435 33 0.229
regulation of cellular component size GO:0032535 121 0.228
Mouse
formation of primary germ layer GO:0001704 77 0.227
negative regulation of apoptotic signaling pathway GO:2001234 104 0.225
embryonic camera type eye development GO:0031076 36 0.225

Bmpr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.878
musculoskeletal system disease DOID:17 0 0.878
connective tissue disease DOID:65 0 0.878
cancer DOID:162 0 0.552
disease of cellular proliferation DOID:14566 0 0.552
heart disease DOID:114 0 0.456
cardiovascular system disease DOID:1287 0 0.456
organ system cancer DOID:0050686 0 0.300