Mus musculus

14 known processes

Vps26a

vacuolar protein sorting 26 homolog A (yeast)

(Aliases: AA407240,Vps26,HB58)

Vps26a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
retrograde transport endosome to golgi GO:0042147 2 0.558
membrane fusion GO:0061025 38 0.345
nucleoside phosphate metabolic process GO:0006753 338 0.234
vesicle organization GO:0016050 60 0.228
vacuolar transport GO:0007034 11 0.176
regulation of intracellular transport GO:0032386 159 0.160
lysosomal transport GO:0007041 10 0.146
purine ribonucleotide metabolic process GO:0009150 290 0.141
cation transport GO:0006812 399 0.134
organelle fusion GO:0048284 28 0.121
purine ribonucleoside metabolic process GO:0046128 241 0.116
ion transmembrane transport GO:0034220 361 0.094
membrane organization GO:0061024 245 0.090
purine nucleoside metabolic process GO:0042278 241 0.088
cytoplasmic transport GO:0016482 234 0.084
nucleobase containing small molecule metabolic process GO:0055086 352 0.081
cellular macromolecule catabolic process GO:0044265 206 0.079
nucleotide metabolic process GO:0009117 332 0.075
inorganic cation transmembrane transport GO:0098662 207 0.074
nucleoside metabolic process GO:0009116 246 0.072
establishment of vesicle localization GO:0051650 81 0.070
negative regulation of intracellular transport GO:0032387 38 0.068
regulation of organelle organization GO:0033043 289 0.066
nitrogen compound transport GO:0071705 271 0.065
organophosphate catabolic process GO:0046434 232 0.061
macromolecule catabolic process GO:0009057 281 0.057
positive regulation of protein catabolic process GO:0045732 60 0.056
cation transmembrane transport GO:0098655 266 0.056
nucleoside triphosphate metabolic process GO:0009141 230 0.052
regulation of cellular catabolic process GO:0031329 242 0.052
carbohydrate derivative catabolic process GO:1901136 231 0.052
cellular homeostasis GO:0019725 240 0.051
protein modification by small protein conjugation GO:0032446 187 0.049
peptide transport GO:0015833 133 0.048
protein catabolic process GO:0030163 221 0.048
intracellular protein transport GO:0006886 204 0.045
ribose phosphate metabolic process GO:0019693 291 0.045
ubiquitin dependent protein catabolic process GO:0006511 129 0.045
negative regulation of cytoplasmic transport GO:1903650 29 0.044
cellular amino acid metabolic process GO:0006520 103 0.044
ras protein signal transduction GO:0007265 77 0.044
purine ribonucleoside catabolic process GO:0046130 205 0.043
vacuole organization GO:0007033 38 0.043
purine nucleoside catabolic process GO:0006152 205 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
cellular amine metabolic process GO:0044106 44 0.040
regulation of cellular component size GO:0032535 121 0.040
regulation of protein catabolic process GO:0042176 108 0.039
endosome to lysosome transport GO:0008333 6 0.039
regulation of anatomical structure size GO:0090066 178 0.038
inorganic ion transmembrane transport GO:0098660 234 0.038
organelle assembly GO:0070925 177 0.038
amine metabolic process GO:0009308 45 0.037
immune effector process GO:0002252 321 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
organonitrogen compound catabolic process GO:1901565 264 0.034
cellular protein catabolic process GO:0044257 155 0.033
cellular ketone metabolic process GO:0042180 84 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
spermatid differentiation GO:0048515 115 0.032
regulation of hormone levels GO:0010817 211 0.031
protein ubiquitination GO:0016567 171 0.031
hydrogen ion transmembrane transport GO:1902600 25 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
amide transport GO:0042886 138 0.031
nucleoside triphosphate catabolic process GO:0009143 205 0.031
response to organonitrogen compound GO:0010243 246 0.030
transmembrane transport GO:0055085 412 0.030
response to light stimulus GO:0009416 135 0.030
cellular response to organonitrogen compound GO:0071417 145 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.029
vesicle fusion GO:0006906 16 0.029
cytokine production GO:0001816 319 0.029
cellular lipid metabolic process GO:0044255 323 0.029
protein localization to organelle GO:0033365 185 0.029
regulation of proteolysis GO:0030162 164 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.028
regulation of cytoplasmic transport GO:1903649 112 0.028
hormone secretion GO:0046879 128 0.028
dna metabolic process GO:0006259 303 0.028
proteasomal protein catabolic process GO:0010498 98 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
positive regulation of secretion GO:0051047 130 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
negative regulation of molecular function GO:0044092 258 0.027
organophosphate biosynthetic process GO:0090407 122 0.027
regulation of vesicle mediated transport GO:0060627 139 0.027
regulation of hydrolase activity GO:0051336 246 0.026
homeostasis of number of cells GO:0048872 210 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
regulation of cell migration GO:0030334 219 0.026
positive regulation of cell death GO:0010942 224 0.026
modification dependent protein catabolic process GO:0019941 133 0.025
nucleotide catabolic process GO:0009166 217 0.025
positive regulation of nucleotide metabolic process GO:0045981 114 0.025
regulation of secretion by cell GO:1903530 249 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
regulation of vacuole organization GO:0044088 4 0.025
positive regulation of organelle organization GO:0010638 128 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
response to peptide hormone GO:0043434 127 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
regulation of secretion GO:0051046 274 0.024
apoptotic signaling pathway GO:0097190 306 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
cellular amide metabolic process GO:0043603 58 0.023
gland development GO:0048732 330 0.023
positive regulation of hydrolase activity GO:0051345 148 0.022
cell substrate adhesion GO:0031589 130 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
regulation of neuron differentiation GO:0045664 281 0.022
maintenance of location GO:0051235 89 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
lysosome organization GO:0007040 21 0.022
peptide hormone secretion GO:0030072 109 0.021
leukocyte mediated immunity GO:0002443 174 0.021
insulin secretion GO:0030073 89 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
phagosome maturation GO:0090382 4 0.020
regulation of cell projection organization GO:0031344 206 0.020
coenzyme metabolic process GO:0006732 52 0.020
purine containing compound metabolic process GO:0072521 311 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
response to insulin GO:0032868 100 0.020
phospholipid metabolic process GO:0006644 87 0.020
small molecule biosynthetic process GO:0044283 132 0.020
protein maturation GO:0051604 176 0.020
regulation of ion transport GO:0043269 215 0.019
endocytosis GO:0006897 168 0.019
divalent metal ion transport GO:0070838 172 0.019
developmental maturation GO:0021700 193 0.019
cation homeostasis GO:0055080 212 0.019
spermatogenesis GO:0007283 284 0.019
locomotory behavior GO:0007626 195 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
regulation of cell cycle GO:0051726 281 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
dendrite development GO:0016358 115 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
mitotic cell cycle process GO:1903047 159 0.019
actin cytoskeleton organization GO:0030036 220 0.018
cellular response to lipid GO:0071396 145 0.018
defense response to bacterium GO:0042742 119 0.018
blood vessel morphogenesis GO:0048514 285 0.018
regulation of mitotic cell cycle phase transition GO:1901990 73 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
glycerolipid metabolic process GO:0046486 122 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
lipid biosynthetic process GO:0008610 179 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
spermatid development GO:0007286 108 0.017
cell type specific apoptotic process GO:0097285 268 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
regulation of peptidase activity GO:0052547 96 0.017
atp metabolic process GO:0046034 75 0.017
rab protein signal transduction GO:0032482 1 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
exocytosis GO:0006887 121 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
regulation of homeostatic process GO:0032844 182 0.017
male gamete generation GO:0048232 285 0.017
divalent inorganic cation transport GO:0072511 178 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
response to peptide GO:1901652 136 0.016
lipid catabolic process GO:0016042 69 0.016
regulation of neuron projection development GO:0010975 169 0.016
defense response to other organism GO:0098542 197 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
nuclear division GO:0000280 158 0.016
protein targeting GO:0006605 143 0.016
nucleoside catabolic process GO:0009164 206 0.016
cellular response to peptide GO:1901653 92 0.016
carbohydrate homeostasis GO:0033500 128 0.016
phosphatidylethanolamine metabolic process GO:0046337 2 0.016
peptidyl amino acid modification GO:0018193 336 0.016
mitochondrial transport GO:0006839 36 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
circulatory system process GO:0003013 197 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
mitochondrion organization GO:0007005 134 0.015
microtubule based process GO:0007017 236 0.015
meiotic cell cycle GO:0051321 122 0.015
mapk cascade GO:0000165 281 0.015
gtp catabolic process GO:0006184 143 0.015
glucose homeostasis GO:0042593 128 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
peptide secretion GO:0002790 114 0.015
receptor recycling GO:0001881 11 0.015
blood circulation GO:0008015 195 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
stem cell maintenance GO:0019827 130 0.015
regulation of cellular response to growth factor stimulus GO:0090287 82 0.015
negative regulation of neuron death GO:1901215 98 0.015
single organism cell adhesion GO:0098602 156 0.015
atp catabolic process GO:0006200 55 0.015
regulation of mapk cascade GO:0043408 248 0.015
cellular chemical homeostasis GO:0055082 215 0.015
transmission of nerve impulse GO:0019226 76 0.015
nucleoside monophosphate catabolic process GO:0009125 59 0.015
actin filament organization GO:0007015 113 0.015
cofactor metabolic process GO:0051186 80 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
negative regulation of cell development GO:0010721 169 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
sequestering of calcium ion GO:0051208 18 0.014
purine containing compound catabolic process GO:0072523 213 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
regulation of body fluid levels GO:0050878 162 0.014
pyridine nucleotide biosynthetic process GO:0019363 4 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
cell adhesion GO:0007155 329 0.014
heterocycle catabolic process GO:0046700 280 0.013
regulation of response to wounding GO:1903034 189 0.013
negative regulation of cell cycle GO:0045786 123 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
regulation of cell motility GO:2000145 236 0.013
mitochondrion degradation GO:0000422 3 0.013
regulation of protein transport GO:0051223 163 0.013
response to oxidative stress GO:0006979 123 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
regulation of protein localization GO:0032880 231 0.013
oxidation reduction process GO:0055114 342 0.013
phagolysosome assembly GO:0001845 3 0.013
regulation of calcium ion transport GO:0051924 69 0.013
regulation of metal ion transport GO:0010959 106 0.013
chromatin organization GO:0006325 206 0.013
rho protein signal transduction GO:0007266 32 0.013
axonogenesis GO:0007409 274 0.013
metal ion homeostasis GO:0055065 189 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
peptidyl serine modification GO:0018209 83 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
neuron death GO:0070997 154 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
lipid transport GO:0006869 98 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
calcium ion transport GO:0006816 159 0.013
carbohydrate metabolic process GO:0005975 230 0.013
organic acid biosynthetic process GO:0016053 86 0.013
protein localization to nucleus GO:0034504 121 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
positive regulation of protein modification process GO:0031401 299 0.012
protein processing GO:0016485 163 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
vesicle localization GO:0051648 86 0.012
protein localization to vacuole GO:0072665 4 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of membrane potential GO:0042391 192 0.012
myeloid cell differentiation GO:0030099 233 0.012
response to radiation GO:0009314 165 0.012
regulation of cytokine production GO:0001817 266 0.012
germ cell development GO:0007281 185 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
leukocyte differentiation GO:0002521 342 0.012
pyridine containing compound metabolic process GO:0072524 14 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
negative regulation of growth GO:0045926 99 0.012
ossification GO:0001503 216 0.012
multicellular organismal signaling GO:0035637 91 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of cell growth GO:0001558 91 0.012
chromatin modification GO:0016568 187 0.012
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.012
wnt signaling pathway GO:0016055 188 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
proton transport GO:0015992 35 0.012
mitotic nuclear division GO:0007067 48 0.012
organelle localization GO:0051640 179 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
regulation of kinase activity GO:0043549 249 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
regulation of binding GO:0051098 111 0.011
nuclear transport GO:0051169 139 0.011
interleukin 8 production GO:0032637 4 0.011
cytoskeleton dependent intracellular transport GO:0030705 50 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
calcium ion homeostasis GO:0055074 127 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
organelle fission GO:0048285 170 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.011
cell maturation GO:0048469 127 0.011
axon cargo transport GO:0008088 33 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
regulation of defense response GO:0031347 233 0.011
translesion synthesis GO:0019985 1 0.011
establishment of synaptic vesicle localization GO:0097480 57 0.011
positive regulation of nervous system development GO:0051962 221 0.011
synapse organization GO:0050808 125 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
striated muscle tissue development GO:0014706 293 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
adult behavior GO:0030534 135 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
response to extracellular stimulus GO:0009991 127 0.011
cell growth GO:0016049 130 0.011
synaptic transmission GO:0007268 329 0.011
regulation of hormone secretion GO:0046883 88 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
positive regulation of cytokine production GO:0001819 174 0.011
organic acid transport GO:0015849 101 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
wound healing GO:0042060 157 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
muscle tissue development GO:0060537 308 0.011
regulation of peptide transport GO:0090087 91 0.011
regulation of neuron death GO:1901214 134 0.011
negative regulation of organelle organization GO:0010639 90 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.010
localization within membrane GO:0051668 4 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
urogenital system development GO:0001655 261 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
positive regulation of cell development GO:0010720 237 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.010
organic hydroxy compound transport GO:0015850 93 0.010
action potential GO:0001508 78 0.010
response to acid chemical GO:0001101 111 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
mitotic cell cycle GO:0000278 195 0.010
pigmentation GO:0043473 71 0.010
cellular ion homeostasis GO:0006873 165 0.010
lipid localization GO:0010876 126 0.010
blastocyst development GO:0001824 80 0.010
oocyte axis specification GO:0007309 2 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
regulation of protein kinase activity GO:0045859 232 0.010
ribonucleotide catabolic process GO:0009261 208 0.010

Vps26a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.109
disease of anatomical entity DOID:7 0 0.109
neurodegenerative disease DOID:1289 0 0.109
nervous system disease DOID:863 0 0.109
parkinson s disease DOID:14330 0 0.042
synucleinopathy DOID:0050890 0 0.042
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.015
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011