Mus musculus

14 known processes

Nr1i2

nuclear receptor subfamily 1, group I, member 2

(Aliases: mPXR,PXR.1,PXR.2,PXR,PXR1,SXR)

Nr1i2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fat soluble vitamin biosynthetic process GO:0042362 4 0.989
Mouse
vitamin d3 metabolic process GO:0070640 3 0.956
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.943
Mouse
vitamin d biosynthetic process GO:0042368 3 0.920
Mouse
exogenous drug catabolic process GO:0042738 1 0.919
Human
calcitriol biosynthetic process from calciol GO:0036378 3 0.915
Mouse
cellular alcohol metabolic process GO:0044107 3 0.911
Mouse
drug catabolic process GO:0042737 2 0.902
Human
cellular lipid metabolic process GO:0044255 323 0.823
Mouse
naphthalene metabolic process GO:0018931 1 0.808
drug metabolic process GO:0017144 4 0.794
Human
lipid biosynthetic process GO:0008610 179 0.753
Mouse
oxidative demethylation GO:0070989 1 0.751
small molecule biosynthetic process GO:0044283 132 0.747
Mouse
sterol homeostasis GO:0055092 45 0.691
Fly
cellular alcohol biosynthetic process GO:0044108 3 0.679
Mouse
secondary alcohol metabolic process GO:1902652 3 0.678
Mouse
lipid homeostasis GO:0055088 63 0.653
Fly
fat soluble vitamin metabolic process GO:0006775 11 0.630
Mouse
alcohol biosynthetic process GO:0046165 43 0.596
Mouse
terpenoid metabolic process GO:0006721 25 0.575
response to phenylpropanoid GO:0080184 22 0.514
alcohol metabolic process GO:0006066 116 0.506
Mouse
isoprenoid metabolic process GO:0006720 29 0.481
medium chain fatty acid metabolic process GO:0051791 1 0.476
organic hydroxy compound biosynthetic process GO:1901617 77 0.466
Mouse
oxidation reduction process GO:0055114 342 0.462
Mouse Fly
lipid localization GO:0010876 126 0.438
Mouse
naphthalene containing compound metabolic process GO:0090420 1 0.430
small molecule catabolic process GO:0044282 71 0.413
Mouse
cholesterol homeostasis GO:0042632 44 0.394
Fly
regulation of hormone levels GO:0010817 211 0.365
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.355
Mouse
polyol metabolic process GO:0019751 26 0.355
Mouse
amine metabolic process GO:0009308 45 0.352
Mouse
retinoid metabolic process GO:0001523 24 0.350
glutamate metabolic process GO:0006536 9 0.345
Mouse
response to organic cyclic compound GO:0014070 198 0.331
Zebrafish Mouse
short chain fatty acid catabolic process GO:0019626 2 0.319
cellular ketone metabolic process GO:0042180 84 0.314
Mouse
cellular amide metabolic process GO:0043603 58 0.297
Mouse
unsaturated fatty acid metabolic process GO:0033559 31 0.276
regulation of cellular amine metabolic process GO:0033238 20 0.267
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.244
Human Zebrafish Mouse Rat
lipid transport GO:0006869 98 0.235
Mouse
anion transport GO:0006820 177 0.220
Mouse
vitamin metabolic process GO:0006766 23 0.216
Mouse
regulation of secretion GO:0051046 274 0.198
Mouse
sulfur compound metabolic process GO:0006790 100 0.197
regulation of system process GO:0044057 200 0.192
xenobiotic catabolic process GO:0042178 1 0.188
fatty acid derivative metabolic process GO:1901568 33 0.187
cofactor metabolic process GO:0051186 80 0.187
organic anion transport GO:0015711 137 0.183
Mouse
lipid catabolic process GO:0016042 69 0.180
Mouse
organic acid catabolic process GO:0016054 51 0.178
Mouse
9 cis retinoic acid metabolic process GO:0042905 5 0.175
positive regulation of cellular amine metabolic process GO:0033240 5 0.173
Mouse
cellular amino acid metabolic process GO:0006520 103 0.173
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.171
positive regulation of estrogen secretion GO:2000863 1 0.169
multi multicellular organism process GO:0044706 109 0.165
Mouse
organic acid biosynthetic process GO:0016053 86 0.164
sensory perception GO:0007600 245 0.153
cellular amine metabolic process GO:0044106 44 0.150
Mouse
steroid biosynthetic process GO:0006694 47 0.147
Mouse
wound healing GO:0042060 157 0.141
Mouse
fatty acid metabolic process GO:0006631 121 0.137
Mouse
cellular response to cadmium ion GO:0071276 3 0.136
lipid storage GO:0019915 36 0.135
retinoic acid metabolic process GO:0042573 12 0.134
response to retinoic acid GO:0032526 56 0.134
Mouse
apoptotic signaling pathway GO:0097190 306 0.131
fibrinolysis GO:0042730 3 0.129
epithelial cell proliferation GO:0050673 174 0.126
Mouse
vitamin biosynthetic process GO:0009110 7 0.121
Mouse
fertilization GO:0009566 127 0.120
organonitrogen compound catabolic process GO:1901565 264 0.120
linoleic acid metabolic process GO:0043651 6 0.119
steroid metabolic process GO:0008202 119 0.117
Mouse
arachidonic acid metabolic process GO:0019369 14 0.113
positive regulation of lipid metabolic process GO:0045834 40 0.111
Mouse
toxin catabolic process GO:0009407 1 0.110
glycerolipid metabolic process GO:0046486 122 0.110
regulation of cellular amino acid metabolic process GO:0006521 5 0.107
Mouse
cellular ion homeostasis GO:0006873 165 0.107
Mouse
brown fat cell differentiation GO:0050873 36 0.100
Mouse
monocarboxylic acid catabolic process GO:0072329 27 0.099
Mouse
positive regulation of steroid hormone secretion GO:2000833 2 0.098
regulation of reactive oxygen species metabolic process GO:2000377 40 0.098
regulation of lipid transport GO:0032368 36 0.098
glutamine family amino acid metabolic process GO:0009064 15 0.097
Mouse
long chain fatty acid metabolic process GO:0001676 26 0.096
placenta development GO:0001890 140 0.096
Mouse
macromolecule catabolic process GO:0009057 281 0.095
transmembrane transport GO:0055085 412 0.094
response to organonitrogen compound GO:0010243 246 0.094
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.094
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.090
Mouse
action potential GO:0001508 78 0.089
Mouse
maintenance of location GO:0051235 89 0.089
cellular response to inorganic substance GO:0071241 37 0.088
Mouse
intestinal absorption GO:0050892 13 0.088
Mouse
positive regulation of fatty acid oxidation GO:0046321 4 0.088
Mouse
regulation of membrane potential GO:0042391 192 0.088
Mouse
carboxylic acid transport GO:0046942 100 0.085
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.085
Mouse
regulation of lipid metabolic process GO:0019216 118 0.085
Mouse
response to drug GO:0042493 75 0.084
Human
keratinocyte migration GO:0051546 3 0.082
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.082
response to metal ion GO:0010038 47 0.082
Mouse
response to bile acid GO:1903412 1 0.080
Mouse
regulation of fibrinolysis GO:0051917 1 0.076
icosanoid metabolic process GO:0006690 33 0.076
ensheathment of neurons GO:0007272 76 0.075
Mouse
9 cis retinoic acid biosynthetic process GO:0042904 5 0.075
regulation of circadian rhythm GO:0042752 58 0.072
Mouse
polyol biosynthetic process GO:0046173 13 0.072
Mouse
response to alkaloid GO:0043279 34 0.069
diterpenoid metabolic process GO:0016101 24 0.069
response to nutrient levels GO:0031667 109 0.068
Mouse Fly
hormone secretion GO:0046879 128 0.068
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.068
acylglycerol metabolic process GO:0006639 55 0.067
response to extracellular stimulus GO:0009991 127 0.067
Mouse Fly
neuron neuron synaptic transmission GO:0007270 69 0.066
response to stilbenoid GO:0035634 22 0.065
peptide metabolic process GO:0006518 46 0.065
cellular response to metal ion GO:0071248 31 0.063
Mouse
blood coagulation GO:0007596 76 0.063
mechanoreceptor differentiation GO:0042490 67 0.061
regulation of postsynaptic membrane potential GO:0060078 48 0.061
purine containing compound metabolic process GO:0072521 311 0.060
alpha amino acid metabolic process GO:1901605 59 0.059
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.058
organophosphate biosynthetic process GO:0090407 122 0.057
gland development GO:0048732 330 0.056
Mouse
acetylcholine catabolic process GO:0006581 1 0.056
defense response to bacterium GO:0042742 119 0.056
cellular calcium ion homeostasis GO:0006874 119 0.056
Mouse
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.056
positive regulation of apoptotic process GO:0043065 217 0.056
Mouse
trophoblast giant cell differentiation GO:0060707 15 0.055
reactive oxygen species metabolic process GO:0072593 84 0.054
keratinocyte proliferation GO:0043616 21 0.054
Mouse
acylglycerol homeostasis GO:0055090 16 0.053
Fly
phospholipid metabolic process GO:0006644 87 0.053
negative regulation of protein metabolic process GO:0051248 282 0.052
cell substrate adhesion GO:0031589 130 0.052
Mouse
diterpenoid biosynthetic process GO:0016102 7 0.051
response to food GO:0032094 17 0.051
Mouse
protein oligomerization GO:0051259 67 0.051
cellular response to acid chemical GO:0071229 68 0.051
Mouse
forebrain development GO:0030900 302 0.050
short chain fatty acid metabolic process GO:0046459 6 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.049
response to inorganic substance GO:0010035 96 0.049
Mouse
secondary metabolite catabolic process GO:0090487 1 0.049
maternal process involved in female pregnancy GO:0060135 32 0.049
Mouse
male gamete generation GO:0048232 285 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.048
terpenoid biosynthetic process GO:0016114 7 0.048
hormone metabolic process GO:0042445 86 0.048
cellular component assembly involved in morphogenesis GO:0010927 139 0.047
lipid modification GO:0030258 65 0.047
Mouse
sensory perception of mechanical stimulus GO:0050954 107 0.047
neutral lipid metabolic process GO:0006638 57 0.047
skeletal system development GO:0001501 356 0.046
Mouse
circadian regulation of gene expression GO:0032922 48 0.046
Mouse
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.046
Mouse
nucleoside monophosphate metabolic process GO:0009123 85 0.045
coenzyme metabolic process GO:0006732 52 0.044
endocytosis GO:0006897 168 0.043
regulation of glutamate metabolic process GO:2000211 1 0.043
Mouse
regulation of defense response GO:0031347 233 0.043
regulation of hydrolase activity GO:0051336 246 0.043
purine nucleoside metabolic process GO:0042278 241 0.043
regulation of ammonia assimilation cycle GO:2001248 1 0.042
Mouse
negative regulation of cytokine production GO:0001818 84 0.042
Mouse
positive regulation of cholesterol homeostasis GO:2000189 2 0.041
regulation of cell projection organization GO:0031344 206 0.041
cellular lipid catabolic process GO:0044242 52 0.041
Mouse
glycosyl compound metabolic process GO:1901657 246 0.040
camera type eye development GO:0043010 266 0.040
negative regulation of molecular function GO:0044092 258 0.040
cofactor transport GO:0051181 4 0.040
negative regulation of fibrinolysis GO:0051918 1 0.040
spermatogenesis GO:0007283 284 0.039
multi organism behavior GO:0051705 62 0.039
rhythmic process GO:0048511 174 0.038
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.038
neuronal action potential GO:0019228 54 0.038
Mouse
regulation of nitrogen cycle metabolic process GO:1903314 1 0.038
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.037
regulation of vitamin d biosynthetic process GO:0060556 1 0.037
Mouse
protein catabolic process GO:0030163 221 0.037
ammonia assimilation cycle GO:0019676 2 0.037
Mouse
ion transmembrane transport GO:0034220 361 0.037
heme metabolic process GO:0042168 16 0.037
membrane lipid metabolic process GO:0006643 53 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.036
triglyceride homeostasis GO:0070328 15 0.036
Fly
regulation of ion transport GO:0043269 215 0.036
carboxylic acid biosynthetic process GO:0046394 86 0.035
circadian rhythm GO:0007623 114 0.035
Mouse
estrogen secretion GO:0035937 1 0.035
cellular response to hormone stimulus GO:0032870 150 0.034
Zebrafish Mouse
dendrite development GO:0016358 115 0.034
regulation of phospholipase c activity GO:1900274 3 0.034
response to oxidative stress GO:0006979 123 0.034
regulation of hormone secretion GO:0046883 88 0.034
Mouse
response to temperature stimulus GO:0009266 55 0.034
ribonucleoside metabolic process GO:0009119 245 0.033
ribose phosphate metabolic process GO:0019693 291 0.033
lactation GO:0007595 25 0.033
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.032
Mouse
translational initiation GO:0006413 24 0.032
positive regulation of protein modification process GO:0031401 299 0.032
defense response to gram negative bacterium GO:0050829 28 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
fatty acid transport GO:0015908 28 0.032
Mouse
transmission of nerve impulse GO:0019226 76 0.031
Mouse
defense response to other organism GO:0098542 197 0.031
aromatic compound catabolic process GO:0019439 286 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
positive regulation of translational initiation by iron GO:0045994 2 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
nucleoside triphosphate metabolic process GO:0009141 230 0.031
g protein coupled receptor signaling pathway GO:0007186 243 0.031
regulation of translation GO:0006417 71 0.030
sensory organ morphogenesis GO:0090596 242 0.030
cholesterol storage GO:0010878 4 0.030
inner ear receptor cell differentiation GO:0060113 61 0.030
response to decreased oxygen levels GO:0036293 59 0.029
Mouse
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.029
regulation of intestinal cholesterol absorption GO:0030300 4 0.029
carboxylic acid catabolic process GO:0046395 51 0.029
Mouse
negative regulation of cell proliferation GO:0008285 296 0.029
Mouse
pigment metabolic process GO:0042440 32 0.029
ameboidal type cell migration GO:0001667 128 0.029
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.029
Mouse
regulation of translational initiation by iron GO:0006447 2 0.028
translation GO:0006412 93 0.028
cellular response to bile acid GO:1903413 1 0.028
Mouse
response to cadmium ion GO:0046686 8 0.028
calcium ion transport GO:0006816 159 0.028
Mouse
porphyrin containing compound metabolic process GO:0006778 22 0.028
embryonic placenta development GO:0001892 98 0.028
glycerophospholipid metabolic process GO:0006650 71 0.028
nucleoside monophosphate catabolic process GO:0009125 59 0.028
sensory perception of pain GO:0019233 47 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
antimicrobial peptide production GO:0002775 2 0.027
monocarboxylic acid transport GO:0015718 44 0.026
Mouse
regulation of transferase activity GO:0051338 263 0.026
positive regulation of hormone secretion GO:0046887 38 0.026
response to peptide hormone GO:0043434 127 0.026
Mouse
bile acid metabolic process GO:0008206 17 0.026
Mouse
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.026
positive regulation of blood pressure GO:0045777 21 0.026
demethylation GO:0070988 23 0.026
exocytosis GO:0006887 121 0.026
regulation of organ morphogenesis GO:2000027 144 0.026
Mouse
heart morphogenesis GO:0003007 178 0.026
organic hydroxy compound transport GO:0015850 93 0.026
cellular response to organic cyclic compound GO:0071407 87 0.026
Zebrafish Mouse
cell differentiation involved in embryonic placenta development GO:0060706 26 0.025
positive regulation of systemic arterial blood pressure GO:0003084 9 0.025
positive regulation of dopamine secretion GO:0033603 2 0.025
retinoic acid biosynthetic process GO:0002138 7 0.025
neuromuscular process GO:0050905 99 0.025
norepinephrine transport GO:0015874 2 0.025
sulfate assimilation GO:0000103 3 0.025
regulation of complement activation classical pathway GO:0030450 1 0.025
biomineral tissue development GO:0031214 64 0.025
Mouse
hexose biosynthetic process GO:0019319 39 0.024
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 80 0.024
generation of ovulation cycle rhythm GO:0060112 1 0.024
positive regulation of secretion GO:0051047 130 0.024
innate immune response GO:0045087 157 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.024
carbohydrate catabolic process GO:0016052 32 0.024
purine nucleoside monophosphate metabolic process GO:0009126 81 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.023
epidermis development GO:0008544 187 0.023
Mouse
ribonucleotide catabolic process GO:0009261 208 0.023
positive regulation of translational initiation GO:0045948 4 0.023
sphingolipid metabolic process GO:0006665 45 0.023
regulation of jak stat cascade GO:0046425 34 0.023
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.023
urea metabolic process GO:0019627 3 0.023
Mouse
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.023
immune effector process GO:0002252 321 0.023
sodium ion transport GO:0006814 73 0.023
nucleotide metabolic process GO:0009117 332 0.023
organophosphate catabolic process GO:0046434 232 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
response to acid chemical GO:0001101 111 0.022
Mouse
nucleoside catabolic process GO:0009164 206 0.022
meiotic cell cycle process GO:1903046 77 0.022
detection of external stimulus GO:0009581 61 0.022
cardiac ventricle morphogenesis GO:0003208 50 0.022
muscle tissue development GO:0060537 308 0.022
maternal placenta development GO:0001893 20 0.022
regulation of response to wounding GO:1903034 189 0.022
endothelial cell proliferation GO:0001935 27 0.022
striated muscle tissue development GO:0014706 293 0.021
steroid catabolic process GO:0006706 7 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
anatomical structure maturation GO:0071695 49 0.021
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
developmental maturation GO:0021700 193 0.021
Mouse
glycerolipid biosynthetic process GO:0045017 50 0.021
isoprenoid biosynthetic process GO:0008299 9 0.021
cardiac muscle tissue morphogenesis GO:0055008 44 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
positive regulation of angiogenesis GO:0045766 46 0.021
heterocycle catabolic process GO:0046700 280 0.021
lipoprotein metabolic process GO:0042157 43 0.021
response to oxygen levels GO:0070482 62 0.021
Mouse
fatty acid oxidation GO:0019395 28 0.021
Mouse
regulation of smooth muscle contraction GO:0006940 22 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
Mouse
auditory receptor cell differentiation GO:0042491 37 0.021
organelle assembly GO:0070925 177 0.021
saturated monocarboxylic acid metabolic process GO:0032788 2 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.020
positive regulation of transferase activity GO:0051347 167 0.020
cellular homeostasis GO:0019725 240 0.020
Mouse
carbohydrate metabolic process GO:0005975 230 0.020
Mouse Fly
endocrine process GO:0050886 39 0.020
succinyl coa metabolic process GO:0006104 1 0.020
organic acid transport GO:0015849 101 0.020
Mouse
toxin metabolic process GO:0009404 5 0.020
fatty acid catabolic process GO:0009062 25 0.020
Mouse
nucleoside metabolic process GO:0009116 246 0.020
detection of abiotic stimulus GO:0009582 60 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
atp catabolic process GO:0006200 55 0.020
cytokine production GO:0001816 319 0.020
Mouse
positive regulation of phospholipase activity GO:0010518 3 0.020
cellular response to lipid GO:0071396 145 0.019
Zebrafish Mouse
negative regulation of response to wounding GO:1903035 77 0.019
cell type specific apoptotic process GO:0097285 268 0.019
cholesterol catabolic process GO:0006707 5 0.019
positive regulation of cell death GO:0010942 224 0.019
Mouse
sensory perception of sound GO:0007605 97 0.019
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.019
protein tetramerization GO:0051262 23 0.019
protein localization to organelle GO:0033365 185 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
dicarboxylic acid metabolic process GO:0043648 18 0.019
Mouse
regulation of cytokine production GO:0001817 266 0.019
Mouse
tetrapyrrole metabolic process GO:0033013 22 0.019
retina development in camera type eye GO:0060041 119 0.019
ovulation cycle GO:0042698 59 0.019
organ regeneration GO:0031100 2 0.019
acetylcholine metabolic process GO:0008291 3 0.019
zymogen activation GO:0031638 41 0.019
cellular chemical homeostasis GO:0055082 215 0.018
Mouse
telencephalon development GO:0021537 186 0.018
nitrogen compound transport GO:0071705 271 0.018
Mouse
positive regulation of carbohydrate metabolic process GO:0045913 30 0.018
Mouse
positive regulation of mammary gland involution GO:1903521 4 0.018
Mouse
regulation of anion transport GO:0044070 27 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
hair cell differentiation GO:0035315 40 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
myosin filament assembly GO:0031034 2 0.018
cell adhesion GO:0007155 329 0.018
Mouse
myosin filament organization GO:0031033 3 0.017
regulation of antimicrobial humoral response GO:0002759 3 0.017
regulation of neuron differentiation GO:0045664 281 0.017
muscle tissue morphogenesis GO:0060415 53 0.017
intracellular protein transport GO:0006886 204 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
innate immune response in mucosa GO:0002227 3 0.017
ribonucleoside monophosphate catabolic process GO:0009158 57 0.017
multicellular organismal aging GO:0010259 24 0.017
germ cell development GO:0007281 185 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
triglyceride metabolic process GO:0006641 51 0.017
neurotransmitter receptor biosynthetic process GO:0045212 1 0.017
blood circulation GO:0008015 195 0.017
lipid oxidation GO:0034440 29 0.017
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.016
cell recognition GO:0008037 83 0.016
acetate ester transport GO:1901374 2 0.016
plasma lipoprotein particle organization GO:0071827 11 0.016
regulation of interleukin 6 production GO:0032675 55 0.016
thermosensory behavior GO:0040040 1 0.016
muscle contraction GO:0006936 101 0.016
regulation of cell activation GO:0050865 289 0.016
regulation of vitamin metabolic process GO:0030656 3 0.016
Mouse
cellular protein complex assembly GO:0043623 116 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
Mouse
pyruvate metabolic process GO:0006090 28 0.016
negative regulation of synapse maturation GO:2000297 2 0.016
myelination GO:0042552 74 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
protein processing GO:0016485 163 0.016
cardiac muscle tissue development GO:0048738 130 0.016
regulation of calcidiol 1 monooxygenase activity GO:0060558 1 0.015
Mouse
dna metabolic process GO:0006259 303 0.015
organic hydroxy compound catabolic process GO:1901616 25 0.015
apoptotic process involved in mammary gland involution GO:0060057 4 0.015
Mouse
response to purine containing compound GO:0014074 28 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
skin development GO:0043588 220 0.015
Mouse
positive regulation of antimicrobial humoral response GO:0002760 2 0.015
endocrine system development GO:0035270 98 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
immune response activating signal transduction GO:0002757 116 0.015
response to xenobiotic stimulus GO:0009410 13 0.015
Human
striated muscle myosin thick filament assembly GO:0071688 1 0.015
membrane hyperpolarization GO:0060081 21 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
Mouse Fly
protein modification by small protein conjugation GO:0032446 187 0.015
axon ensheathment GO:0008366 76 0.015
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.015
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.015
positive regulation of fat cell differentiation GO:0045600 32 0.015
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
Mouse
negative regulation of cell development GO:0010721 169 0.015
regulation of steroid biosynthetic process GO:0050810 26 0.014
Mouse
positive regulation of ion transport GO:0043270 65 0.014
regulation of digestive system process GO:0044058 13 0.014
respiratory system development GO:0060541 190 0.014
hydrogen transport GO:0006818 35 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of protein kinase activity GO:0045859 232 0.014
cellular biogenic amine metabolic process GO:0006576 28 0.014
protein lipid complex subunit organization GO:0071825 12 0.014
multicellular organismal signaling GO:0035637 91 0.014
Mouse
detection of mechanical stimulus GO:0050982 27 0.014
nuclear division GO:0000280 158 0.014
homeostasis of number of cells GO:0048872 210 0.014
glycoprotein metabolic process GO:0009100 116 0.014
divalent metal ion transport GO:0070838 172 0.014
Mouse
positive regulation of catecholamine secretion GO:0033605 2 0.014
regulation of neuron projection development GO:0010975 169 0.014
response to insulin GO:0032868 100 0.014
Mouse
glandular epithelial cell differentiation GO:0002067 38 0.014
muscle system process GO:0003012 141 0.014
regulation of tumor necrosis factor production GO:0032680 49 0.014
renal tubular secretion GO:0097254 2 0.014
monosaccharide biosynthetic process GO:0046364 44 0.014
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
proton transport GO:0015992 35 0.014
adipose tissue development GO:0060612 25 0.013
Mouse
negative regulation of blood coagulation GO:0030195 11 0.013
ventricular cardiac muscle tissue development GO:0003229 38 0.013
digestion GO:0007586 40 0.013
Mouse
cation transport GO:0006812 399 0.013
Mouse
regulation of antimicrobial peptide production GO:0002784 1 0.013
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.013
fat cell differentiation GO:0045444 160 0.013
Mouse
maintenance of protein location in nucleus GO:0051457 2 0.013
jak stat cascade GO:0007259 42 0.013
regulation of feeding behavior GO:0060259 3 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
response to transition metal nanoparticle GO:1990267 11 0.013
glycolytic process GO:0006096 20 0.013
digestive tract morphogenesis GO:0048546 147 0.013
purine containing compound catabolic process GO:0072523 213 0.013
establishment of vesicle localization GO:0051650 81 0.013
positive regulation of growth GO:0045927 104 0.013
ceramide metabolic process GO:0006672 31 0.013
ear development GO:0043583 200 0.013
detection of stimulus GO:0051606 84 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
pancreatic pp cell fate commitment GO:0003329 2 0.013
regulation of blood pressure GO:0008217 93 0.013
metal ion homeostasis GO:0055065 189 0.013
Mouse
regulation of intracellular transport GO:0032386 159 0.013
anion transmembrane transport GO:0098656 71 0.013
protein targeting GO:0006605 143 0.013

Nr1i2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.090
vascular disease DOID:178 0 0.090
cardiovascular system disease DOID:1287 0 0.090
artery disease DOID:0050828 0 0.022
hypertension DOID:10763 0 0.019
essential hypertension DOID:10825 0 0.019
nervous system disease DOID:863 0 0.013