Mus musculus

26 known processes

Htr3b

5-hydroxytryptamine (serotonin) receptor 3B

(Aliases: 5-HT3B)

Htr3b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of action potential GO:0098900 4 0.255
norepinephrine transport GO:0015874 2 0.184
forebrain development GO:0030900 302 0.092
regulation of renin secretion into blood stream GO:1900133 4 0.081
neuronal action potential GO:0019228 54 0.080
detection of stimulus GO:0051606 84 0.078
positive regulation of nervous system development GO:0051962 221 0.075
embryonic organ morphogenesis GO:0048562 276 0.074
conditioned taste aversion GO:0001661 4 0.073
atrial ventricular junction remodeling GO:0003294 2 0.073
cell communication by chemical coupling GO:0010643 2 0.067
gland development GO:0048732 330 0.063
sensory perception of chemical stimulus GO:0007606 51 0.058
positive regulation of protein phosphorylation GO:0001934 242 0.057
regulation of cell activation GO:0050865 289 0.056
dopamine transport GO:0015872 15 0.056
milk ejection GO:0060156 1 0.055
nucleoside phosphate metabolic process GO:0006753 338 0.047
defense response to other organism GO:0098542 197 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.045
organonitrogen compound catabolic process GO:1901565 264 0.045
transmission of nerve impulse GO:0019226 76 0.044
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 0.043
ion transmembrane transport GO:0034220 361 0.042
cation transport GO:0006812 399 0.042
av node cell to bundle of his cell communication GO:0086067 2 0.041
t cell activation GO:0042110 289 0.041
regulation of dopamine metabolic process GO:0042053 10 0.040
positive regulation of protein modification process GO:0031401 299 0.040
ventricular cardiac muscle cell action potential GO:0086005 4 0.039
transmembrane transport GO:0055085 412 0.039
regulation of cell migration GO:0030334 219 0.038
norepinephrine secretion GO:0048243 2 0.038
response to radiation GO:0009314 165 0.038
catecholamine transport GO:0051937 21 0.038
placenta development GO:0001890 140 0.038
foramen ovale closure GO:0035922 1 0.037
neuron migration GO:0001764 122 0.037
mesenchyme development GO:0060485 152 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.037
carbohydrate metabolic process GO:0005975 230 0.037
ribonucleotide metabolic process GO:0009259 291 0.036
stem cell development GO:0048864 219 0.036
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.036
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.036
regulation of ion transport GO:0043269 215 0.036
regulation of blood pressure GO:0008217 93 0.036
sensory perception of light stimulus GO:0050953 54 0.036
regulation of heart contraction GO:0008016 77 0.036
oxidation reduction process GO:0055114 342 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.035
regulation of muscle system process GO:0090257 80 0.034
lens development in camera type eye GO:0002088 62 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
muscle system process GO:0003012 141 0.033
sensory perception GO:0007600 245 0.033
g protein coupled receptor signaling pathway GO:0007186 243 0.033
ear morphogenesis GO:0042471 118 0.032
sa node cell action potential GO:0086015 4 0.032
immune effector process GO:0002252 321 0.032
inflammatory response GO:0006954 244 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
regulation of heart rate GO:0002027 36 0.032
nitrogen compound transport GO:0071705 271 0.031
appendage development GO:0048736 166 0.031
aromatic compound catabolic process GO:0019439 286 0.031
b cell activation GO:0042113 161 0.030
regulation of neuron differentiation GO:0045664 281 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
regionalization GO:0003002 337 0.029
positive regulation of cell development GO:0010720 237 0.029
mapk cascade GO:0000165 281 0.029
organ growth GO:0035265 117 0.029
skeletal system development GO:0001501 356 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
cellular amine metabolic process GO:0044106 44 0.028
visual perception GO:0007601 52 0.028
nucleotide metabolic process GO:0009117 332 0.028
response to light stimulus GO:0009416 135 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
bmp signaling pathway GO:0030509 93 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
cytokine production GO:0001816 319 0.027
stem cell differentiation GO:0048863 268 0.026
regulation of anatomical structure size GO:0090066 178 0.026
taurine transport GO:0015734 1 0.026
digestive tract development GO:0048565 190 0.026
detection of stimulus involved in sensory perception GO:0050906 44 0.026
heart contraction GO:0060047 93 0.026
defense response to bacterium GO:0042742 119 0.025
regulation of membrane depolarization during action potential GO:0098902 1 0.025
embryonic appendage morphogenesis GO:0035113 126 0.025
negative regulation of growth GO:0045926 99 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.025
respiratory system development GO:0060541 190 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
regulation of membrane potential GO:0042391 192 0.024
regulation of secretion by cell GO:1903530 249 0.024
dopamine catabolic process GO:0042420 4 0.024
limb morphogenesis GO:0035108 149 0.024
ras protein signal transduction GO:0007265 77 0.023
renal system process GO:0003014 48 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
action potential GO:0001508 78 0.023
positive regulation of secretion GO:0051047 130 0.022
endocrine system development GO:0035270 98 0.022
regulation of norepinephrine secretion GO:0014061 2 0.022
ear development GO:0043583 200 0.022
endocrine process GO:0050886 39 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
locomotory behavior GO:0007626 195 0.022
purine containing compound metabolic process GO:0072521 311 0.022
negative regulation of defense response GO:0031348 77 0.022
positive regulation of catecholamine secretion GO:0033605 2 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
regulation of cell projection organization GO:0031344 206 0.020
positive regulation of dopamine secretion GO:0033603 2 0.020
endocytosis GO:0006897 168 0.020
l amino acid transport GO:0015807 32 0.020
organophosphate catabolic process GO:0046434 232 0.020
sensory perception of smell GO:0007608 26 0.020
social behavior GO:0035176 21 0.019
response to cocaine GO:0042220 14 0.019
cell adhesion GO:0007155 329 0.019
regulation of membrane depolarization during cardiac muscle cell action potential GO:1900825 1 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
regulation of defense response GO:0031347 233 0.019
leukocyte differentiation GO:0002521 342 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
blood circulation GO:0008015 195 0.018
regulation of secretion GO:0051046 274 0.018
response to extracellular stimulus GO:0009991 127 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
appendage morphogenesis GO:0035107 149 0.018
negative regulation of cell development GO:0010721 169 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
regulation of gtp catabolic process GO:0033124 113 0.018
regulation of catecholamine metabolic process GO:0042069 10 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
positive regulation of cell activation GO:0050867 158 0.018
response to organonitrogen compound GO:0010243 246 0.018
glucose import GO:0046323 32 0.018
cell differentiation in spinal cord GO:0021515 53 0.017
sensory perception of mechanical stimulus GO:0050954 107 0.017
divalent inorganic cation transport GO:0072511 178 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
monoamine transport GO:0015844 33 0.017
synaptic transmission GO:0007268 329 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
somatotropin secreting cell differentiation GO:0060126 4 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
cellular homeostasis GO:0019725 240 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of system process GO:0044057 200 0.016
camera type eye development GO:0043010 266 0.016
potassium ion transmembrane transport GO:0071805 43 0.016
ventricular septum morphogenesis GO:0060412 27 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
specification of organ position GO:0010159 3 0.016
defecation GO:0030421 1 0.016
serotonin uptake GO:0051610 3 0.016
midgut development GO:0007494 4 0.016
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
synaptic transmission involved in micturition GO:0060084 3 0.016
connective tissue development GO:0061448 179 0.016
leukocyte mediated immunity GO:0002443 174 0.016
regulation of cardiac muscle cell action potential GO:0098901 1 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
response to alkaloid GO:0043279 34 0.016
sensory organ morphogenesis GO:0090596 242 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
humoral immune response GO:0006959 57 0.016
regulation of muscle contraction GO:0006937 49 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
photoreceptor cell differentiation GO:0046530 52 0.015
neuromuscular process GO:0050905 99 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
regulation of cell motility GO:2000145 236 0.015
positive regulation of blood pressure GO:0045777 21 0.015
response to nutrient levels GO:0031667 109 0.015
blood vessel morphogenesis GO:0048514 285 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
embryonic heart tube morphogenesis GO:0003143 51 0.015
organic hydroxy compound transport GO:0015850 93 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
regulation of mapk cascade GO:0043408 248 0.015
heart process GO:0003015 94 0.015
positive regulation of neuron projection development GO:0010976 79 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
regulation of tube size GO:0035150 57 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.015
purine containing compound biosynthetic process GO:0072522 70 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
corticotropin releasing hormone secretion GO:0043396 2 0.015
tissue remodeling GO:0048771 102 0.015
cell communication by electrical coupling GO:0010644 4 0.014
positive regulation of transferase activity GO:0051347 167 0.014
regulation of b cell activation GO:0050864 81 0.014
metal ion homeostasis GO:0055065 189 0.014
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.014
multicellular organismal signaling GO:0035637 91 0.014
epithelial cell development GO:0002064 159 0.014
detection of external stimulus GO:0009581 61 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
wnt signaling pathway GO:0016055 188 0.014
circulatory system process GO:0003013 197 0.014
wound healing GO:0042060 157 0.014
regulation of neuron projection development GO:0010975 169 0.014
cellular ketone metabolic process GO:0042180 84 0.014
regulation of response to wounding GO:1903034 189 0.014
regulation of multi organism process GO:0043900 111 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
cyclic purine nucleotide metabolic process GO:0052652 43 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
cation homeostasis GO:0055080 212 0.014
muscle contraction GO:0006936 101 0.014
sensory perception of sound GO:0007605 97 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of blood circulation GO:1903522 93 0.013
pituitary gland development GO:0021983 38 0.013
regulation of systemic arterial blood pressure GO:0003073 61 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of stem cell proliferation GO:0072091 78 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of glial cell differentiation GO:0045685 41 0.013
neurotransmitter transport GO:0006836 76 0.013
nucleoside metabolic process GO:0009116 246 0.013
diencephalon development GO:0021536 63 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
septum primum development GO:0003284 4 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
regulation of actin filament based process GO:0032970 99 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of protein kinase activity GO:0045859 232 0.013
pallium development GO:0021543 120 0.013
regulation of biomineral tissue development GO:0070167 33 0.013
digestive system development GO:0055123 200 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.013
dna metabolic process GO:0006259 303 0.012
myeloid leukocyte migration GO:0097529 57 0.012
heterocycle catabolic process GO:0046700 280 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
mesodermal cell migration GO:0008078 4 0.012
b cell mediated immunity GO:0019724 71 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
positive regulation of stem cell proliferation GO:2000648 59 0.012
negative regulation of action potential GO:0045759 1 0.012
male gamete generation GO:0048232 285 0.012
mesenchymal cell development GO:0014031 93 0.012
positive regulation of epidermal growth factor activated receptor activity GO:0045741 2 0.012
apoptotic signaling pathway GO:0097190 306 0.012
renal system development GO:0072001 225 0.012
adaptive immune response GO:0002250 155 0.012
single fertilization GO:0007338 82 0.012
neural tube development GO:0021915 160 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
negative regulation of blood pressure GO:0045776 22 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
cerebral cortex neuron differentiation GO:0021895 19 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
glycine transport GO:0015816 4 0.012
fertilization GO:0009566 127 0.012
positive regulation of b cell activation GO:0050871 49 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
circadian sleep wake cycle non rem sleep GO:0042748 2 0.012
positive regulation of kinase activity GO:0033674 155 0.012
embryonic placenta development GO:0001892 98 0.012
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.012
determination of heart left right asymmetry GO:0061371 48 0.011
regulation of blood vessel size GO:0050880 56 0.011
regulation of neurotransmitter transport GO:0051588 35 0.011
spinal cord development GO:0021510 81 0.011
beta alanine transport GO:0001762 1 0.011
inner ear morphogenesis GO:0042472 101 0.011
bone remodeling GO:0046849 53 0.011
defense response to gram negative bacterium GO:0050829 28 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
detection of chemical stimulus involved in sensory perception GO:0050907 10 0.011
regulation of organ growth GO:0046620 61 0.011
cartilage development GO:0051216 140 0.011
multi multicellular organism process GO:0044706 109 0.011
amine metabolic process GO:0009308 45 0.011
regulation of transmembrane transport GO:0034762 128 0.011
hormone metabolic process GO:0042445 86 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
proteoglycan metabolic process GO:0006029 38 0.011
histamine induced gastric acid secretion GO:0001697 1 0.011
striated muscle tissue development GO:0014706 293 0.011
stem cell proliferation GO:0072089 117 0.011
cation transmembrane transport GO:0098655 266 0.011
cell activation involved in immune response GO:0002263 126 0.011
regulation of reproductive process GO:2000241 66 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
defense response to virus GO:0051607 68 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
response to monosaccharide GO:0034284 67 0.011
regulation of cell cycle GO:0051726 281 0.011
regulation of hormone levels GO:0010817 211 0.011
leukocyte migration GO:0050900 124 0.011
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
glucose transport GO:0015758 56 0.010
t cell proliferation GO:0042098 120 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
operant conditioning GO:0035106 2 0.010
regulation of transferase activity GO:0051338 263 0.010
response to lipopolysaccharide GO:0032496 128 0.010
chemotaxis GO:0006935 247 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
gliogenesis GO:0042063 141 0.010
negative regulation of camp mediated signaling GO:0043951 3 0.010
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.010
cardiac atrium morphogenesis GO:0003209 23 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.010
negative regulation of nervous system development GO:0051961 156 0.010
sulfur compound metabolic process GO:0006790 100 0.010
glycosaminoglycan metabolic process GO:0030203 34 0.010
biomineral tissue development GO:0031214 64 0.010
regulation of bone mineralization GO:0030500 31 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
glycoprotein metabolic process GO:0009100 116 0.010
neural precursor cell proliferation GO:0061351 121 0.010

Htr3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.031
disease of anatomical entity DOID:7 0 0.031
eye and adnexa disease DOID:1492 0 0.031
nervous system disease DOID:863 0 0.031
eye disease DOID:5614 0 0.026
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
bone disease DOID:0080001 0 0.011