Mus musculus

204 known processes

Cyr61

cysteine rich protein 61

(Aliases: Igfbp10,AI325051,CCN1)

Cyr61 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel morphogenesis GO:0048514 285 0.899
cell adhesion GO:0007155 329 0.898
intussusceptive angiogenesis GO:0002041 2 0.812
cell substrate adhesion GO:0031589 130 0.809
cellular response to growth factor stimulus GO:0071363 197 0.787
Mouse
response to growth factor GO:0070848 198 0.769
Mouse
response to transforming growth factor beta GO:0071559 88 0.747
skeletal muscle organ development GO:0060538 163 0.745
placenta development GO:0001890 140 0.716
wound healing GO:0042060 157 0.711
Human
regulation of hydrolase activity GO:0051336 246 0.691
blood vessel endothelial cell migration GO:0043534 23 0.679
cell matrix adhesion GO:0007160 68 0.668
Mouse
regulation of peptidase activity GO:0052547 96 0.658
regulation of cell migration GO:0030334 219 0.645
response to fibroblast growth factor GO:0071774 47 0.610
Mouse
axonogenesis GO:0007409 274 0.602
placenta blood vessel development GO:0060674 31 0.566
cell growth GO:0016049 130 0.565
Mouse
positive regulation of proteolysis GO:0045862 85 0.556
epithelial cell migration GO:0010631 63 0.556
regulation of plasminogen activation GO:0010755 4 0.538
single organismal cell cell adhesion GO:0016337 131 0.522
positive regulation of cell migration GO:0030335 109 0.500
positive regulation of cell death GO:0010942 224 0.498
regulation of cell motility GO:2000145 236 0.468
single organism cell adhesion GO:0098602 156 0.464
regulation of cysteine type endopeptidase activity GO:2000116 65 0.454
membrane lipid biosynthetic process GO:0046467 32 0.450
chorio allantoic fusion GO:0060710 8 0.448
embryonic placenta development GO:0001892 98 0.443
tissue migration GO:0090130 68 0.430
axon regeneration GO:0031103 12 0.425
labyrinthine layer development GO:0060711 49 0.421
positive regulation of cell motility GO:2000147 116 0.420
regulation of protein kinase activity GO:0045859 232 0.420
Human
sphingolipid biosynthetic process GO:0030148 26 0.420
cellular response to oxidative stress GO:0034599 76 0.418
regulation of angiogenesis GO:0045765 81 0.409
fibrinolysis GO:0042730 3 0.405
ameboidal type cell migration GO:0001667 128 0.404
angiogenesis GO:0001525 201 0.404
positive regulation of programmed cell death GO:0043068 218 0.404
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.397
regulation of proteolysis GO:0030162 164 0.394
negative regulation of vasculature development GO:1901343 26 0.387
chemotaxis GO:0006935 247 0.385
Rat
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.378
striated muscle tissue development GO:0014706 293 0.371
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.364
forebrain development GO:0030900 302 0.356
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.356
regulation of apoptotic signaling pathway GO:2001233 197 0.356
regulation of ceramide biosynthetic process GO:2000303 1 0.352
epithelium migration GO:0090132 63 0.350
ceramide biosynthetic process GO:0046513 20 0.346
regulation of mapk cascade GO:0043408 248 0.344
Human
coagulation GO:0050817 78 0.340
muscle tissue development GO:0060537 308 0.337
positive regulation of apoptotic process GO:0043065 217 0.326
cardiac chamber development GO:0003205 108 0.324
regulation of blood vessel endothelial cell migration GO:0043535 12 0.320
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.314
Mouse
regulation of endopeptidase activity GO:0052548 89 0.312
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.306
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycle GO:0031660 1 0.303
extrinsic apoptotic signaling pathway GO:0097191 126 0.302
heart morphogenesis GO:0003007 178 0.301
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.298
Human
negative regulation of intracellular signal transduction GO:1902532 167 0.291
regulation of cellular response to stress GO:0080135 159 0.289
labyrinthine layer morphogenesis GO:0060713 21 0.275
regulation of vasculature development GO:1901342 88 0.270
connective tissue development GO:0061448 179 0.268
sphingolipid metabolic process GO:0006665 45 0.265
cardiac chamber morphogenesis GO:0003206 93 0.263
protein processing GO:0016485 163 0.260
regulation of cell cycle GO:0051726 281 0.254
endocytosis GO:0006897 168 0.253
regulation of fibrinolysis GO:0051917 1 0.253
regulation of organelle organization GO:0033043 289 0.247
negative regulation of fat cell differentiation GO:0045599 36 0.246
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.245
nerve development GO:0021675 67 0.244
cellular response to gamma radiation GO:0071480 4 0.240
negative regulation of phosphorylation GO:0042326 166 0.237
regulation of protein serine threonine kinase activity GO:0071900 157 0.230
long term synaptic potentiation GO:0060291 25 0.230
regulation of epithelial cell migration GO:0010632 35 0.228
cell adhesion mediated by integrin GO:0033627 18 0.224
epithelial cell development GO:0002064 159 0.223
regulation of kinase activity GO:0043549 249 0.221
Human
negative regulation of endothelial cell migration GO:0010596 4 0.220
negative regulation of response to wounding GO:1903035 77 0.219
negative regulation of protein metabolic process GO:0051248 282 0.217
negative regulation of molecular function GO:0044092 258 0.215
skeletal muscle cell differentiation GO:0035914 66 0.215
endothelial cell migration GO:0043542 44 0.214
regulation of nucleotide metabolic process GO:0006140 169 0.214
response to interleukin 1 GO:0070555 11 0.212
positive regulation of mrna 3 end processing GO:0031442 5 0.210
transforming growth factor beta2 production GO:0032906 2 0.202
regulation of ovulation GO:0060278 3 0.197
lung development GO:0030324 164 0.191
Mouse
regulation of neuron projection development GO:0010975 169 0.189
substrate dependent cell migration cell attachment to substrate GO:0006931 2 0.184
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.181
Mouse
response to oxidative stress GO:0006979 123 0.181
ossification GO:0001503 216 0.181
protein maturation GO:0051604 176 0.180
regulation of endothelial cell migration GO:0010594 22 0.175
skeletal system development GO:0001501 356 0.174
negative regulation of phosphate metabolic process GO:0045936 184 0.173
regulation of transferase activity GO:0051338 263 0.169
Human
axon guidance GO:0007411 141 0.168
phagocytosis GO:0006909 66 0.167
response to reactive oxygen species GO:0000302 56 0.166
dna metabolic process GO:0006259 303 0.165
mesoderm development GO:0007498 100 0.163
synaptic transmission GO:0007268 329 0.162
vitellogenesis GO:0007296 2 0.162
integrin mediated signaling pathway GO:0007229 27 0.160
Mouse
skeletal system morphogenesis GO:0048705 203 0.160
Mouse
positive regulation of mapk cascade GO:0043410 170 0.159
blood circulation GO:0008015 195 0.159
positive regulation of osteoclast differentiation GO:0045672 15 0.159
glial cell differentiation GO:0010001 131 0.159
fat cell differentiation GO:0045444 160 0.157
negative regulation of hydrolase activity GO:0051346 71 0.157
actin filament organization GO:0007015 113 0.157
regulation of cell adhesion mediated by integrin GO:0033628 13 0.155
positive regulation of phospholipase activity GO:0010518 3 0.154
regulation of histone modification GO:0031056 56 0.153
jnk cascade GO:0007254 72 0.152
macromolecule deacylation GO:0098732 37 0.152
myeloid cell differentiation GO:0030099 233 0.149
epithelial cell proliferation GO:0050673 174 0.148
cell chemotaxis GO:0060326 81 0.148
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.146
Mouse
regulation of transforming growth factor beta2 production GO:0032909 2 0.146
lateral line system development GO:0048925 1 0.145
response to hypoxia GO:0001666 58 0.145
digestive tract development GO:0048565 190 0.145
regionalization GO:0003002 337 0.145
hemostasis GO:0007599 78 0.145
response to organic cyclic compound GO:0014070 198 0.144
cognition GO:0050890 149 0.142
guanosine containing compound metabolic process GO:1901068 144 0.138
neuron projection guidance GO:0097485 141 0.137
regulation of reactive oxygen species metabolic process GO:2000377 40 0.136
extracellular matrix organization GO:0030198 147 0.135
camera type eye development GO:0043010 266 0.133
negative regulation of phosphorus metabolic process GO:0010563 184 0.133
regulation of response to wounding GO:1903034 189 0.131
positive regulation of angiogenesis GO:0045766 46 0.128
engulfment of apoptotic cell GO:0043652 3 0.125
stem cell differentiation GO:0048863 268 0.124
response to oxygen levels GO:0070482 62 0.124
response to decreased oxygen levels GO:0036293 59 0.124
mapk cascade GO:0000165 281 0.121
Human
positive regulation of fibroblast proliferation GO:0048146 20 0.117
anatomical structure homeostasis GO:0060249 145 0.116
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.116
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.116
cell junction organization GO:0034330 77 0.115
positive regulation of peptidase activity GO:0010952 49 0.115
regulation of cartilage development GO:0061035 44 0.115
regulation of cell adhesion GO:0030155 154 0.114
embryonic organ morphogenesis GO:0048562 276 0.113
positive regulation of epithelial cell migration GO:0010634 19 0.113
regulation of fat cell differentiation GO:0045598 81 0.112
regeneration GO:0031099 38 0.111
negative regulation of cellular protein metabolic process GO:0032269 247 0.111
neuron projection regeneration GO:0031102 14 0.110
positive regulation of organelle organization GO:0010638 128 0.110
regulation of cytokine production GO:0001817 266 0.110
gastrulation GO:0007369 116 0.109
digestive tract morphogenesis GO:0048546 147 0.109
apoptotic signaling pathway GO:0097190 306 0.108
negative regulation of kinase activity GO:0033673 81 0.108
apoptotic process involved in morphogenesis GO:0060561 25 0.108
response to extracellular stimulus GO:0009991 127 0.107
mesoderm morphogenesis GO:0048332 64 0.107
forebrain cell migration GO:0021885 58 0.106
regulation of map kinase activity GO:0043405 120 0.105
mesenchyme development GO:0060485 152 0.105
telencephalon development GO:0021537 186 0.104
protein deacetylation GO:0006476 32 0.104
response to peptide GO:1901652 136 0.104
salivary gland morphogenesis GO:0007435 33 0.103
positive regulation of cell adhesion GO:0045785 80 0.103
sensory system development GO:0048880 3 0.102
negative regulation of neuron projection regeneration GO:0070571 3 0.101
synapse organization GO:0050808 125 0.101
learning GO:0007612 98 0.100
positive regulation of neuron projection development GO:0010976 79 0.100
chromatin organization GO:0006325 206 0.099
embryonic process involved in female pregnancy GO:0060136 7 0.099
osteoclast differentiation GO:0030316 62 0.099
response to organophosphorus GO:0046683 22 0.099
organonitrogen compound biosynthetic process GO:1901566 192 0.098
positive regulation of cardiac muscle contraction GO:0060452 2 0.098
membrane lipid metabolic process GO:0006643 53 0.098
amine metabolic process GO:0009308 45 0.098
epithelial to mesenchymal transition GO:0001837 47 0.098
regulation of cellular amino acid metabolic process GO:0006521 5 0.098
cellular response to extracellular stimulus GO:0031668 81 0.097
negative regulation of smooth muscle cell migration GO:0014912 2 0.096
reactive oxygen species metabolic process GO:0072593 84 0.096
substrate dependent cell migration GO:0006929 18 0.095
negative regulation of ovulation GO:0060280 1 0.094
actomyosin structure organization GO:0031032 56 0.093
cell junction assembly GO:0034329 52 0.093
purine ribonucleoside catabolic process GO:0046130 205 0.093
apoptotic process involved in development GO:1902742 28 0.093
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.093
nucleobase containing small molecule metabolic process GO:0055086 352 0.093
regulation of cellular component biogenesis GO:0044087 181 0.093
multicellular organismal homeostasis GO:0048871 164 0.092
Mouse
embryonic placenta morphogenesis GO:0060669 25 0.091
stem cell development GO:0048864 219 0.091
stress activated protein kinase signaling cascade GO:0031098 81 0.090
negative regulation of blood vessel morphogenesis GO:2000181 25 0.090
chondrocyte differentiation GO:0002062 72 0.090
Mouse
striated muscle cell development GO:0055002 125 0.089
regulation of endothelial cell proliferation GO:0001936 23 0.088
central nervous system neuron development GO:0021954 67 0.088
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.088
negative regulation of protein phosphorylation GO:0001933 126 0.087
digestive system development GO:0055123 200 0.086
positive regulation of hydrolase activity GO:0051345 148 0.086
respiratory system development GO:0060541 190 0.085
Mouse
neuron death GO:0070997 154 0.085
female sex differentiation GO:0046660 84 0.085
inner ear morphogenesis GO:0042472 101 0.085
developmental cell growth GO:0048588 84 0.084
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.083
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.081
metanephric glomerular mesangium development GO:0072223 3 0.081
hindbrain development GO:0030902 128 0.081
response to monosaccharide GO:0034284 67 0.079
cellular nitrogen compound catabolic process GO:0044270 280 0.078
cell type specific apoptotic process GO:0097285 268 0.078
positive regulation of endothelial cell migration GO:0010595 12 0.076
locomotory behavior GO:0007626 195 0.076
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.075
response to corticosteroid GO:0031960 20 0.075
mesenchymal cell differentiation GO:0048762 107 0.075
zymogen activation GO:0031638 41 0.075
telencephalon cell migration GO:0022029 55 0.074
negative regulation of endopeptidase activity GO:0010951 44 0.074
formation of primary germ layer GO:0001704 77 0.073
negative regulation of neuron death GO:1901215 98 0.073
purine containing compound metabolic process GO:0072521 311 0.073
i kappab kinase nf kappab signaling GO:0007249 85 0.073
respiratory tube development GO:0030323 167 0.072
Mouse
cartilage development GO:0051216 140 0.072
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.072
gland development GO:0048732 330 0.071
response to follicle stimulating hormone GO:0032354 1 0.071
positive regulation of cell development GO:0010720 237 0.070
leukocyte differentiation GO:0002521 342 0.070
urogenital system development GO:0001655 261 0.069
cellular amino acid metabolic process GO:0006520 103 0.069
negative regulation of proteolysis GO:0045861 74 0.068
membrane organization GO:0061024 245 0.068
cellular response to external stimulus GO:0071496 88 0.067
female gamete generation GO:0007292 74 0.067
carbohydrate metabolic process GO:0005975 230 0.067
keratinocyte migration GO:0051546 3 0.067
collagen biosynthetic process GO:0032964 7 0.066
ribonucleoside catabolic process GO:0042454 206 0.066
platelet aggregation GO:0070527 20 0.066
hippocampus development GO:0021766 52 0.066
response to camp GO:0051591 14 0.065
regulation of establishment of protein localization GO:0070201 181 0.065
glomerulus development GO:0032835 40 0.064
organic hydroxy compound metabolic process GO:1901615 203 0.064
actin filament bundle assembly GO:0051017 40 0.064
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.064
regulation of cellular catabolic process GO:0031329 242 0.064
negative regulation of fibrinolysis GO:0051918 1 0.064
decidualization GO:0046697 10 0.064
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.064
developmental maturation GO:0021700 193 0.063
negative regulation of angiogenesis GO:0016525 25 0.063
positive regulation of neuron differentiation GO:0045666 141 0.062
cellular amine metabolic process GO:0044106 44 0.062
negative regulation of protein processing GO:0010955 79 0.061
regulation of translation GO:0006417 71 0.061
regulation of chromatin modification GO:1903308 57 0.061
heterocycle catabolic process GO:0046700 280 0.061
striated muscle myosin thick filament assembly GO:0071688 1 0.060
cerebral cortex cell migration GO:0021795 44 0.060
nucleotide metabolic process GO:0009117 332 0.059
response to inorganic substance GO:0010035 96 0.059
multicellular organismal macromolecule metabolic process GO:0044259 19 0.058
regulation of protein maturation GO:1903317 96 0.058
regulation of neuron apoptotic process GO:0043523 122 0.058
regulation of myeloid leukocyte differentiation GO:0002761 58 0.058
purine ribonucleotide catabolic process GO:0009154 208 0.058
endothelial cell proliferation GO:0001935 27 0.058
positive regulation of chemotaxis GO:0050921 38 0.058
regulation of protein deacetylation GO:0090311 17 0.058
response to calcium ion GO:0051592 20 0.058
regulation of stem cell differentiation GO:2000736 50 0.057
regulation of wnt signaling pathway GO:0030111 123 0.057
neuron apoptotic process GO:0051402 142 0.057
compound eye development GO:0048749 1 0.057
ventricular septum development GO:0003281 42 0.057
regulation of neuronal synaptic plasticity GO:0048168 30 0.057
circulatory system process GO:0003013 197 0.057
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.056
Human
epithelial cell morphogenesis GO:0003382 41 0.056
positive regulation of protein modification process GO:0031401 299 0.056
Human
response to mineralocorticoid GO:0051385 1 0.055
brain segmentation GO:0035284 3 0.055
regulation of antimicrobial humoral response GO:0002759 3 0.055
regulation of neuron death GO:1901214 134 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
response to steroid hormone GO:0048545 56 0.055
muscle system process GO:0003012 141 0.055
regulation of cell activation GO:0050865 289 0.055
regulation of purine nucleotide metabolic process GO:1900542 169 0.055
learning or memory GO:0007611 148 0.055
cellular response to peptide GO:1901653 92 0.054
platelet activation GO:0030168 40 0.054
regulation of chromosome organization GO:0033044 83 0.054
positive regulation of muscle contraction GO:0045933 10 0.054
chondroblast differentiation GO:0060591 2 0.054
cation transport GO:0006812 399 0.054
regulation of synaptic transmission glutamatergic GO:0051966 19 0.054
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.054
negative regulation of stem cell differentiation GO:2000737 14 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.053
mesenchymal cell development GO:0014031 93 0.053
synapse assembly GO:0007416 56 0.053
ribose phosphate metabolic process GO:0019693 291 0.053
cardiac septum development GO:0003279 59 0.053
lens morphogenesis in camera type eye GO:0002089 24 0.053
regulation of cellular response to growth factor stimulus GO:0090287 82 0.053
regulation of cell substrate adhesion GO:0010810 73 0.053
regulation of system process GO:0044057 200 0.053
regulation of multicellular organismal metabolic process GO:0044246 14 0.053
glycosyl compound metabolic process GO:1901657 246 0.052
glomerular visceral epithelial cell differentiation GO:0072112 10 0.052
cytokine production GO:0001816 319 0.052
labyrinthine layer blood vessel development GO:0060716 21 0.052
sprouting angiogenesis GO:0002040 26 0.052
segmentation GO:0035282 93 0.051
regulation of neuron differentiation GO:0045664 281 0.051
ceramide metabolic process GO:0006672 31 0.051
positive regulation of stress activated mapk cascade GO:0032874 48 0.051
regulation of inflammatory response GO:0050727 147 0.050
organophosphate catabolic process GO:0046434 232 0.050
cell recognition GO:0008037 83 0.050
negative regulation of cell proliferation GO:0008285 296 0.050
central nervous system projection neuron axonogenesis GO:0021952 21 0.050
positive regulation of endopeptidase activity GO:0010950 43 0.049
positive regulation of epithelial cell proliferation GO:0050679 68 0.049
muscle cell differentiation GO:0042692 261 0.049
regulation of epithelial to mesenchymal transition GO:0010717 22 0.049
t cell differentiation in thymus GO:0033077 77 0.049
limbic system development GO:0021761 72 0.049
histone modification GO:0016570 159 0.049
vascular wound healing GO:0061042 3 0.048
protein deacylation GO:0035601 36 0.048
regulation of vascular wound healing GO:0061043 2 0.047
elastic fiber assembly GO:0048251 4 0.047
regulation of fibroblast proliferation GO:0048145 34 0.047
fibroblast proliferation GO:0048144 35 0.047
negative regulation of transferase activity GO:0051348 85 0.047
intracellular protein transport GO:0006886 204 0.047
mesoderm formation GO:0001707 62 0.046
positive regulation of lipid biosynthetic process GO:0046889 18 0.046
positive regulation of histone deacetylation GO:0031065 7 0.046
histone deacetylation GO:0016575 26 0.046
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.046
oocyte construction GO:0007308 2 0.045
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.045
negative regulation of cell substrate adhesion GO:0010812 16 0.045
positive regulation of myeloid cell differentiation GO:0045639 43 0.045
brown fat cell differentiation GO:0050873 36 0.045
regulation of leukocyte differentiation GO:1902105 159 0.045
gene silencing by mirna GO:0035195 10 0.044
positive regulation of actin filament bundle assembly GO:0032233 11 0.044
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 5 0.044
nuclear transport GO:0051169 139 0.044
negative regulation of cell adhesion mediated by integrin GO:0033629 2 0.044
synaptic transmission glutamatergic GO:0035249 36 0.044
response to peptide hormone GO:0043434 127 0.044
positive regulation of histone modification GO:0031058 28 0.043
regulation of cell projection organization GO:0031344 206 0.043
response to amino acid GO:0043200 37 0.043
macromolecule catabolic process GO:0009057 281 0.043
positive regulation of protein kinase activity GO:0045860 144 0.043
Human
positive regulation of cell activation GO:0050867 158 0.043
cellular response to hypoxia GO:0071456 17 0.043
chromatin modification GO:0016568 187 0.043
regulation of peptide transport GO:0090087 91 0.043
lamellipodium organization GO:0097581 29 0.043
skin development GO:0043588 220 0.042
regulation of histone deacetylation GO:0031063 12 0.042
rhythmic process GO:0048511 174 0.042
positive regulation of protein phosphorylation GO:0001934 242 0.042
Human
stress activated mapk cascade GO:0051403 80 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
morphogenesis of a branching epithelium GO:0061138 193 0.041
regulation of smad protein import into nucleus GO:0060390 3 0.041
single organism reproductive behavior GO:0044704 3 0.041
septum transversum development GO:0003343 2 0.041
cellular response to cytokine stimulus GO:0071345 189 0.041
response to hyperoxia GO:0055093 2 0.041
oocyte axis specification GO:0007309 2 0.041
regulation of chromatin organization GO:1902275 57 0.040
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.040
regulation of stress activated mapk cascade GO:0032872 69 0.040
regulation of interleukin 8 production GO:0032677 3 0.040
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.040
leukocyte chemotaxis GO:0030595 69 0.040
innervation GO:0060384 22 0.040
canonical wnt signaling pathway GO:0060070 130 0.040
motor neuron axon guidance GO:0008045 26 0.040
heart valve morphogenesis GO:0003179 21 0.040
negative regulation of protein modification process GO:0031400 163 0.040
kidney vasculature development GO:0061440 15 0.040
positive regulation of growth GO:0045927 104 0.039
regulation of wound healing GO:0061041 40 0.039
female gonad development GO:0008585 71 0.039
adherens junction organization GO:0034332 28 0.039
atrial septum development GO:0003283 12 0.039
atrioventricular valve morphogenesis GO:0003181 13 0.039
cardiac septum morphogenesis GO:0060411 46 0.039
regulation of synaptic plasticity GO:0048167 87 0.038
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.038
regulation of endothelial cell chemotaxis GO:2001026 1 0.038
regulation of lipase activity GO:0060191 15 0.038
response to organonitrogen compound GO:0010243 246 0.038
pallium development GO:0021543 120 0.038
regulation of brown fat cell differentiation GO:0090335 5 0.038
ovulation GO:0030728 15 0.038
mitotic cell cycle process GO:1903047 159 0.038
nephron epithelium development GO:0072009 92 0.038
regulation of intracellular transport GO:0032386 159 0.038
negative regulation of defense response GO:0031348 77 0.038
positive regulation of cell cycle GO:0045787 92 0.038
chronological cell aging GO:0001300 1 0.038
carbohydrate biosynthetic process GO:0016051 74 0.038
cell migration involved in sprouting angiogenesis GO:0002042 9 0.037
cellular response to inorganic substance GO:0071241 37 0.037
organelle assembly GO:0070925 177 0.037
cell maturation GO:0048469 127 0.037
covalent chromatin modification GO:0016569 163 0.037
response to drug GO:0042493 75 0.037
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.037
response to purine containing compound GO:0014074 28 0.036
general adaptation syndrome GO:0051866 2 0.036
regulation of cellular component size GO:0032535 121 0.036
mesenchymal cell apoptotic process involved in metanephros development GO:1900200 4 0.036
positive regulation of map kinase activity GO:0043406 84 0.036
regulation of jnk cascade GO:0046328 62 0.036
glomerular mesangial cell proliferation GO:0072110 3 0.036
associative learning GO:0008306 61 0.035
positive regulation of chromosome organization GO:2001252 33 0.035
nucleotide catabolic process GO:0009166 217 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
nucleoside triphosphate catabolic process GO:0009143 205 0.035
positive regulation of nervous system development GO:0051962 221 0.035
smad protein signal transduction GO:0060395 21 0.035
cardiac muscle contraction GO:0060048 32 0.035
hippo signaling GO:0035329 11 0.035
regulation of cell growth GO:0001558 91 0.035
Mouse
cell cell adhesion GO:0098609 41 0.035
regulation of canonical wnt signaling pathway GO:0060828 82 0.035
cell substrate junction assembly GO:0007044 24 0.034
positive regulation of interleukin 8 production GO:0032757 2 0.034
insemination GO:0007320 6 0.034
cellular response to dna damage stimulus GO:0006974 207 0.034
negative regulation of cell adhesion GO:0007162 45 0.034
positive regulation of neuron apoptotic process GO:0043525 25 0.034
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.034
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.034
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.034
interleukin 8 production GO:0032637 4 0.034
regulation of lipid metabolic process GO:0019216 118 0.034
negative regulation of cellular amine metabolic process GO:0033239 1 0.034
maternal placenta development GO:0001893 20 0.033

Cyr61 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.436
disease of anatomical entity DOID:7 0 0.436
cardiovascular system disease DOID:1287 0 0.436
muscular disease DOID:0080000 0 0.138
musculoskeletal system disease DOID:17 0 0.138
nervous system disease DOID:863 0 0.054
muscle tissue disease DOID:66 0 0.047
myopathy DOID:423 0 0.047
neuromuscular disease DOID:440 0 0.037
charcot marie tooth disease DOID:10595 0 0.037
neuropathy DOID:870 0 0.037
sensory system disease DOID:0050155 0 0.034