Mus musculus

18 known processes

Tro

trophinin

(Aliases: Trol,Maged3,Maged3l,magphinin,Tnn,AA409408)

Tro biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neuron differentiation GO:0045664 281 0.213
regulation of organelle organization GO:0033043 289 0.161
regulation of cellular ketone metabolic process GO:0010565 66 0.127
cellular ketone metabolic process GO:0042180 84 0.125
chemotaxis GO:0006935 247 0.123
axonogenesis GO:0007409 274 0.114
regulation of neuron apoptotic process GO:0043523 122 0.113
actin cytoskeleton organization GO:0030036 220 0.112
regulation of cellular amino acid metabolic process GO:0006521 5 0.106
axon guidance GO:0007411 141 0.103
regulation of cell motility GO:2000145 236 0.087
genetic imprinting GO:0071514 27 0.080
body morphogenesis GO:0010171 45 0.077
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.077
maintenance of presynaptic active zone structure GO:0048790 1 0.075
regulation of cellular amine metabolic process GO:0033238 20 0.070
cellular amine metabolic process GO:0044106 44 0.069
regulation of neuron projection development GO:0010975 169 0.057
cellular amino acid metabolic process GO:0006520 103 0.057
regulation of cytoskeleton organization GO:0051493 122 0.056
hindbrain development GO:0030902 128 0.050
positive regulation of cellular amine metabolic process GO:0033240 5 0.050
neuron projection guidance GO:0097485 141 0.047
peptidyl amino acid modification GO:0018193 336 0.047
dendrite development GO:0016358 115 0.047
amine metabolic process GO:0009308 45 0.047
positive regulation of protein kinase activity GO:0045860 144 0.046
Mouse
cognition GO:0050890 149 0.045
positive regulation of nervous system development GO:0051962 221 0.043
protein polymerization GO:0051258 57 0.043
methylation GO:0032259 134 0.042
purine nucleoside triphosphate metabolic process GO:0009144 226 0.042
dna metabolic process GO:0006259 303 0.041
small gtpase mediated signal transduction GO:0007264 97 0.041
rac protein signal transduction GO:0016601 13 0.041
rho protein signal transduction GO:0007266 32 0.041
neuron migration GO:0001764 122 0.041
actin filament organization GO:0007015 113 0.040
ribonucleoside metabolic process GO:0009119 245 0.039
axon target recognition GO:0007412 4 0.039
nucleotide metabolic process GO:0009117 332 0.039
defecation GO:0030421 1 0.039
regulation of actin filament based process GO:0032970 99 0.039
cell recognition GO:0008037 83 0.039
macromolecule methylation GO:0043414 120 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.038
sialylation GO:0097503 14 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
compound eye development GO:0048749 1 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
actin filament polymerization GO:0030041 44 0.037
positive regulation of protein modification process GO:0031401 299 0.036
Mouse
anion transport GO:0006820 177 0.036
leukocyte differentiation GO:0002521 342 0.035
response to organonitrogen compound GO:0010243 246 0.034
organic cyclic compound catabolic process GO:1901361 295 0.034
myeloid leukocyte differentiation GO:0002573 119 0.034
regulation of cell cycle GO:0051726 281 0.034
negative regulation of neuron death GO:1901215 98 0.033
regulation of actin filament length GO:0030832 45 0.033
regulation of cell projection organization GO:0031344 206 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
positive regulation of programmed cell death GO:0043068 218 0.032
Mouse
regulation of actin nucleation GO:0051125 4 0.031
organonitrogen compound catabolic process GO:1901565 264 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
transmembrane transport GO:0055085 412 0.031
cerebellum development GO:0021549 77 0.030
membrane organization GO:0061024 245 0.030
negative regulation of nervous system development GO:0051961 156 0.030
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.030
regulation of cell migration GO:0030334 219 0.030
engulfment of apoptotic cell GO:0043652 3 0.029
striated muscle tissue development GO:0014706 293 0.029
aromatic compound catabolic process GO:0019439 286 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
regulation of actin cytoskeleton organization GO:0032956 84 0.029
regulation of hydrolase activity GO:0051336 246 0.029
myeloid cell differentiation GO:0030099 233 0.027
developmental growth involved in morphogenesis GO:0060560 138 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
microtubule based process GO:0007017 236 0.027
sensory perception GO:0007600 245 0.027
nucleoside catabolic process GO:0009164 206 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.027
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
dendritic spine morphogenesis GO:0060997 22 0.026
heterocycle catabolic process GO:0046700 280 0.026
neuron apoptotic process GO:0051402 142 0.026
synapse organization GO:0050808 125 0.025
mitochondrion transport along microtubule GO:0047497 3 0.025
protein processing GO:0016485 163 0.025
axon cargo transport GO:0008088 33 0.025
mitotic cell cycle GO:0000278 195 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
regulation of intracellular transport GO:0032386 159 0.024
positive regulation of cellular component biogenesis GO:0044089 94 0.024
macromolecule catabolic process GO:0009057 281 0.024
cell type specific apoptotic process GO:0097285 268 0.024
regulation of neuron death GO:1901214 134 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.023
oligosaccharide biosynthetic process GO:0009312 7 0.023
learning or memory GO:0007611 148 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
positive regulation of organelle organization GO:0010638 128 0.023
rap protein signal transduction GO:0032486 3 0.023
neuron death GO:0070997 154 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
lateral inhibition GO:0046331 1 0.023
negative regulation of cellular component organization GO:0051129 194 0.022
organelle localization GO:0051640 179 0.022
fasciculation of sensory neuron axon GO:0097155 3 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
Mouse
dna alkylation GO:0006305 43 0.022
negative regulation of cell development GO:0010721 169 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.021
axonal fasciculation GO:0007413 15 0.021
apoptotic signaling pathway GO:0097190 306 0.021
Mouse
dendritic spine organization GO:0097061 26 0.021
dorsal ventral axon guidance GO:0033563 3 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
regulation of protein localization GO:0032880 231 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
regulation of ion transport GO:0043269 215 0.021
metencephalon development GO:0022037 89 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.020
gtp metabolic process GO:0046039 144 0.020
muscle tissue development GO:0060537 308 0.020
synaptic vesicle membrane organization GO:0048499 1 0.020
actin polymerization or depolymerization GO:0008154 54 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
asymmetric neuroblast division GO:0055059 1 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
negative regulation of cell motility GO:2000146 61 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
Mouse
central nervous system neuron differentiation GO:0021953 162 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
organophosphate catabolic process GO:0046434 232 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
Mouse
camera type eye development GO:0043010 266 0.019
positive regulation of actin filament polymerization GO:0030838 26 0.019
glycosyl compound catabolic process GO:1901658 206 0.018
axon regeneration GO:0031103 12 0.018
synaptic transmission GO:0007268 329 0.018
ras protein signal transduction GO:0007265 77 0.018
positive regulation of cytoskeleton organization GO:0051495 49 0.018
purine containing compound catabolic process GO:0072523 213 0.018
negative regulation of molecular function GO:0044092 258 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
cellular response to abiotic stimulus GO:0071214 56 0.018
negative regulation of cell migration GO:0030336 59 0.018
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.017
positive regulation of protein export from nucleus GO:0046827 4 0.017
cardiac cell fate specification GO:0060912 2 0.017
myeloid leukocyte migration GO:0097529 57 0.017
translation GO:0006412 93 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
regulation of cellular component size GO:0032535 121 0.017
regulation of stem cell division GO:2000035 4 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
response to osmotic stress GO:0006970 21 0.017
organic anion transport GO:0015711 137 0.017
regulation of cell adhesion GO:0030155 154 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
protein localization to membrane GO:0072657 108 0.016
protein maturation GO:0051604 176 0.016
regulation of kinase activity GO:0043549 249 0.016
Mouse
intracellular protein transport GO:0006886 204 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
Mouse
multicellular organismal response to stress GO:0033555 62 0.016
cell division GO:0051301 120 0.016
regulation of cell cycle process GO:0010564 160 0.016
regulation of glial cell differentiation GO:0045685 41 0.016
negative regulation of endothelial cell migration GO:0010596 4 0.016
gland development GO:0048732 330 0.016
female gamete generation GO:0007292 74 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
regulation of nucleocytoplasmic transport GO:0046822 73 0.016
ephrin receptor signaling pathway GO:0048013 20 0.016
positive regulation of map kinase activity GO:0043406 84 0.015
Mouse
forebrain development GO:0030900 302 0.015
cellular response to osmotic stress GO:0071470 7 0.015
oocyte axis specification GO:0007309 2 0.015
neural precursor cell proliferation GO:0061351 121 0.015
chromatin modification GO:0016568 187 0.015
regulation of protein complex assembly GO:0043254 83 0.015
terminal button organization GO:0072553 3 0.015
neuron recognition GO:0008038 25 0.015
cellular protein complex assembly GO:0043623 116 0.015
peripheral nervous system axon regeneration GO:0014012 2 0.015
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.015
regulation of stress activated mapk cascade GO:0032872 69 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
regulation of membrane potential GO:0042391 192 0.015
cellular chemical homeostasis GO:0055082 215 0.015
negative regulation of ovulation GO:0060280 1 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
regulation of translation GO:0006417 71 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
peripheral nervous system neuron axonogenesis GO:0048936 3 0.014
gliogenesis GO:0042063 141 0.014
positive regulation of myelination GO:0031643 5 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
mitotic cytokinesis GO:0000281 4 0.014
cation transmembrane transport GO:0098655 266 0.014
organelle fission GO:0048285 170 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
endocytosis GO:0006897 168 0.014
cellular response to carbohydrate stimulus GO:0071322 50 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
neuron projection regeneration GO:0031102 14 0.014
regulation of anatomical structure size GO:0090066 178 0.014
calcium ion transport GO:0006816 159 0.014
transcription from rna polymerase iii promoter GO:0006383 3 0.013
regulation of vasculature development GO:1901342 88 0.013
multicellular organism growth GO:0035264 161 0.013
negative regulation of organelle organization GO:0010639 90 0.013
protein autophosphorylation GO:0046777 61 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
mesodermal cell migration GO:0008078 4 0.013
dna methylation GO:0006306 43 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
establishment of vesicle localization GO:0051650 81 0.013
regulation of ovulation GO:0060278 3 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
oocyte maturation GO:0001556 18 0.013
nucleoside metabolic process GO:0009116 246 0.013
protein oligomerization GO:0051259 67 0.013
dendritic spine development GO:0060996 30 0.013
negative regulation of immune system process GO:0002683 209 0.013
negative regulation of cell activation GO:0050866 111 0.013
regulation of myeloid leukocyte differentiation GO:0002761 58 0.013
nucleotide catabolic process GO:0009166 217 0.013
parathyroid hormone secretion GO:0035898 2 0.013
cell adhesion GO:0007155 329 0.013
membrane tubulation GO:0097320 4 0.013
sensory organ morphogenesis GO:0090596 242 0.013
positive regulation of cell death GO:0010942 224 0.013
Mouse
regulation of t cell activation GO:0050863 170 0.013
mitotic cell cycle process GO:1903047 159 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
regulation of cell activation GO:0050865 289 0.013
cellular homeostasis GO:0019725 240 0.013
bmp signaling pathway GO:0030509 93 0.013
positive regulation of protein complex assembly GO:0031334 45 0.013
mesoderm development GO:0007498 100 0.013
respiratory system development GO:0060541 190 0.013
neuromuscular process GO:0050905 99 0.012
response to organic cyclic compound GO:0014070 198 0.012
gtp catabolic process GO:0006184 143 0.012
response to inorganic substance GO:0010035 96 0.012
dna modification GO:0006304 50 0.012
response to amino acid GO:0043200 37 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of actin filament polymerization GO:0030833 38 0.012
cytoplasmic transport GO:0016482 234 0.012
embryonic body morphogenesis GO:0010172 10 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
cellular response to inorganic substance GO:0071241 37 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
morphogenesis of a polarized epithelium GO:0001738 37 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
photoreceptor cell morphogenesis GO:0008594 3 0.012
regulation of dendritic spine development GO:0060998 22 0.012
l alpha amino acid transmembrane transport GO:1902475 23 0.012
pole plasm assembly GO:0007315 2 0.012
regulation of peptidase activity GO:0052547 96 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
sensory perception of pain GO:0019233 47 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
regulation of multi organism process GO:0043900 111 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
negative regulation of growth GO:0045926 99 0.012
learning GO:0007612 98 0.012
regulation of establishment of protein localization GO:0070201 181 0.011
establishment of glial blood brain barrier GO:0060857 2 0.011
fat cell differentiation GO:0045444 160 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.011
nitrogen compound transport GO:0071705 271 0.011
negative regulation of cell cycle GO:0045786 123 0.011
response to peptide GO:1901652 136 0.011
development of primary sexual characteristics GO:0045137 143 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
endomembrane system organization GO:0010256 147 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
central nervous system neuron axonogenesis GO:0021955 28 0.011
dna replication GO:0006260 52 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
telencephalon development GO:0021537 186 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
hormone secretion GO:0046879 128 0.011
peptidyl serine modification GO:0018209 83 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
cation homeostasis GO:0055080 212 0.011
stem cell development GO:0048864 219 0.011
extracellular matrix organization GO:0030198 147 0.011
negative regulation of dna replication GO:0008156 4 0.011
negative regulation of protein modification process GO:0031400 163 0.011
fasciculation of motor neuron axon GO:0097156 2 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
oocyte construction GO:0007308 2 0.011
retinal ganglion cell axon guidance GO:0031290 18 0.011
cell chemotaxis GO:0060326 81 0.011
response to monosaccharide GO:0034284 67 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
microtubule nucleation GO:0007020 2 0.010
plasma membrane organization GO:0007009 90 0.010
skeletal muscle organ development GO:0060538 163 0.010
regulation of feeding behavior GO:0060259 3 0.010
cerebellar cortex development GO:0021695 48 0.010
single organism cell adhesion GO:0098602 156 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
stem cell differentiation GO:0048863 268 0.010
carboxylic acid transport GO:0046942 100 0.010
regulation of mapk cascade GO:0043408 248 0.010
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.010
regulation of map kinase activity GO:0043405 120 0.010
Mouse
cytokine production GO:0001816 319 0.010
microtubule polymerization or depolymerization GO:0031109 26 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
regulation of protein maturation GO:1903317 96 0.010
neural tube development GO:0021915 160 0.010
positive regulation of cell development GO:0010720 237 0.010
mapk cascade GO:0000165 281 0.010
Mouse
endochondral bone morphogenesis GO:0060350 50 0.010
proteoglycan metabolic process GO:0006029 38 0.010
replication fork protection GO:0048478 1 0.010
organic acid transport GO:0015849 101 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
covalent chromatin modification GO:0016569 163 0.010

Tro disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.012
central nervous system disease DOID:331 0 0.012
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
congenital nervous system abnormality DOID:2490 0 0.011