Mus musculus

134 known processes

Slc6a3

solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

(Aliases: DAT,Dat1)

Slc6a3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of dopamine secretion GO:0014059 9 1.000
dopamine metabolic process GO:0042417 23 1.000
catecholamine metabolic process GO:0006584 30 1.000
monoamine transport GO:0015844 33 1.000
response to ammonium ion GO:0060359 21 1.000
dopamine secretion GO:0014046 9 1.000
dopamine transport GO:0015872 15 1.000
synaptic transmission GO:0007268 329 0.999
Mouse
response to cocaine GO:0042220 14 0.999
catecholamine transport GO:0051937 21 0.999
response to alkaloid GO:0043279 34 0.999
long term synaptic potentiation GO:0060291 25 0.998
regulation of catecholamine secretion GO:0050433 12 0.998
catecholamine secretion GO:0050432 15 0.998
positive regulation of cellular amine metabolic process GO:0033240 5 0.994
dopamine uptake involved in synaptic transmission GO:0051583 4 0.994
cellular amine metabolic process GO:0044106 44 0.993
neurotransmitter transport GO:0006836 76 0.993
Mouse Rat
conditioned taste aversion GO:0001661 4 0.990
regulation of cellular ketone metabolic process GO:0010565 66 0.986
organic hydroxy compound transport GO:0015850 93 0.985
dopamine uptake GO:0090494 4 0.984
organic hydroxy compound metabolic process GO:1901615 203 0.984
phenol containing compound metabolic process GO:0018958 60 0.983
amine metabolic process GO:0009308 45 0.981
regulation of neurotransmitter transport GO:0051588 35 0.979
behavioral response to cocaine GO:0048148 10 0.972
locomotory behavior GO:0007626 195 0.971
organonitrogen compound biosynthetic process GO:1901566 192 0.970
amine transport GO:0015837 21 0.968
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 2 0.968
serotonin transport GO:0006837 11 0.965
Mouse
nitrogen compound transport GO:0071705 271 0.960
g protein coupled receptor signaling pathway GO:0007186 243 0.959
regulation of cellular amine metabolic process GO:0033238 20 0.959
g protein coupled receptor internalization GO:0002031 3 0.958
feeding behavior GO:0007631 62 0.953
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.951
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.948
calcium ion transport GO:0006816 159 0.939
positive regulation of secretion by cell GO:1903532 114 0.934
catecholamine biosynthetic process GO:0042423 11 0.934
regulation of synaptic plasticity GO:0048167 87 0.932
regulation of ion transport GO:0043269 215 0.930
regulation of catecholamine metabolic process GO:0042069 10 0.930
organophosphate biosynthetic process GO:0090407 122 0.928
regulation of dopamine uptake involved in synaptic transmission GO:0051584 2 0.922
regulation of membrane potential GO:0042391 192 0.917
divalent inorganic cation homeostasis GO:0072507 138 0.913
organic hydroxy compound biosynthetic process GO:1901617 77 0.911
response to organic cyclic compound GO:0014070 198 0.910
limbic system development GO:0021761 72 0.907
regulation of cellular amino acid metabolic process GO:0006521 5 0.904
adult behavior GO:0030534 135 0.892
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.885
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.885
regulation of circadian sleep wake cycle GO:0042749 3 0.880
circadian sleep wake cycle GO:0042745 5 0.877
response to organonitrogen compound GO:0010243 246 0.872
generation of ovulation cycle rhythm GO:0060112 1 0.865
regulation of secretion by cell GO:1903530 249 0.865
phenol containing compound biosynthetic process GO:0046189 21 0.864
regulation of synaptic transmission dopaminergic GO:0032225 8 0.860
smooth muscle contraction GO:0006939 44 0.859
circadian sleep wake cycle rem sleep GO:0042747 1 0.855
neuron neuron synaptic transmission GO:0007270 69 0.839
synaptic transmission involved in micturition GO:0060084 3 0.835
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.834
positive regulation of secretion GO:0051047 130 0.833
response to metal ion GO:0010038 47 0.831
Rat
dopamine biosynthetic process GO:0042416 6 0.830
positive regulation of catecholamine secretion GO:0033605 2 0.829
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.827
cellular ketone metabolic process GO:0042180 84 0.824
angiogenesis GO:0001525 201 0.823
positive regulation of protein kinase activity GO:0045860 144 0.822
purine nucleotide metabolic process GO:0006163 302 0.819
cellular amino acid metabolic process GO:0006520 103 0.814
forebrain cell migration GO:0021885 58 0.812
cellular metal ion homeostasis GO:0006875 151 0.811
carboxylic acid transport GO:0046942 100 0.808
Mouse
phospholipid metabolic process GO:0006644 87 0.805
cellular lipid metabolic process GO:0044255 323 0.801
positive regulation of dopamine secretion GO:0033603 2 0.801
regulation of secretion GO:0051046 274 0.801
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.797
response to nutrient levels GO:0031667 109 0.796
cation transport GO:0006812 399 0.794
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.793
peptide secretion GO:0002790 114 0.788
calcium ion homeostasis GO:0055074 127 0.787
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.780
response to extracellular stimulus GO:0009991 127 0.779
organic anion transport GO:0015711 137 0.772
Mouse
anion transport GO:0006820 177 0.770
Mouse
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.770
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.768
release of sequestered calcium ion into cytosol GO:0051209 42 0.763
regulation of dopamine metabolic process GO:0042053 10 0.761
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.761
positive regulation of kinase activity GO:0033674 155 0.760
regulation of transferase activity GO:0051338 263 0.756
visual learning GO:0008542 44 0.751
axonogenesis GO:0007409 274 0.749
purine ribonucleotide metabolic process GO:0009150 290 0.742
negative regulation of action potential GO:0045759 1 0.741
memory GO:0007613 58 0.738
dopamine receptor signaling pathway GO:0007212 16 0.730
learning or memory GO:0007611 148 0.728
positive regulation of transferase activity GO:0051347 167 0.724
regulation of neuron projection development GO:0010975 169 0.718
regulation of synaptic transmission glutamatergic GO:0051966 19 0.715
action potential GO:0001508 78 0.714
regulation of neurotransmitter secretion GO:0046928 29 0.712
cognition GO:0050890 149 0.710
cellular calcium ion homeostasis GO:0006874 119 0.709
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.708
regulation of neurotransmitter levels GO:0001505 87 0.707
Mouse
neurotransmitter uptake GO:0001504 14 0.700
Mouse
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.694
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.694
peptidyl tyrosine modification GO:0018212 145 0.692
response to nicotine GO:0035094 6 0.687
Rat
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.686
negative regulation of cell development GO:0010721 169 0.683
negative regulation of ion transport GO:0043271 28 0.683
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.682
membrane depolarization GO:0051899 64 0.681
positive regulation of protein modification process GO:0031401 299 0.676
synapse organization GO:0050808 125 0.676
forebrain development GO:0030900 302 0.676
divalent metal ion transport GO:0070838 172 0.676
monocarboxylic acid metabolic process GO:0032787 191 0.676
metal ion homeostasis GO:0055065 189 0.673
peptidyl amino acid modification GO:0018193 336 0.670
cytosolic calcium ion homeostasis GO:0051480 70 0.660
gliogenesis GO:0042063 141 0.656
negative regulation of neurotransmitter transport GO:0051589 7 0.655
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.649
mitochondrion organization GO:0007005 134 0.646
regulation of ion homeostasis GO:2000021 64 0.645
response to amphetamine GO:0001975 16 0.644
neuron migration GO:0001764 122 0.644
regulation of neuronal synaptic plasticity GO:0048168 30 0.641
neuromuscular process GO:0050905 99 0.641
leukocyte proliferation GO:0070661 172 0.638
acid secretion GO:0046717 33 0.638
regulation of postsynaptic membrane potential GO:0060078 48 0.638
negative regulation of response to wounding GO:1903035 77 0.638
adult locomotory behavior GO:0008344 91 0.635
positive regulation of ion transport GO:0043270 65 0.635
hormone secretion GO:0046879 128 0.634
central nervous system neuron differentiation GO:0021953 162 0.632
peptide hormone secretion GO:0030072 109 0.632
cellular carbohydrate metabolic process GO:0044262 119 0.631
neuron death GO:0070997 154 0.631
response to oxidative stress GO:0006979 123 0.631
pallium development GO:0021543 120 0.629
norepinephrine secretion GO:0048243 2 0.628
fat cell differentiation GO:0045444 160 0.624
response to amine GO:0014075 16 0.624
energy derivation by oxidation of organic compounds GO:0015980 77 0.623
negative regulation of cellular component organization GO:0051129 194 0.615
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.604
nucleoside metabolic process GO:0009116 246 0.602
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.598
cellular chemical homeostasis GO:0055082 215 0.595
regulation of blood pressure GO:0008217 93 0.595
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.594
regulation of neurotransmitter uptake GO:0051580 6 0.593
negative regulation of adenylate cyclase activity GO:0007194 1 0.590
regulation of body fluid levels GO:0050878 162 0.588
heart process GO:0003015 94 0.588
carbohydrate metabolic process GO:0005975 230 0.587
neuron apoptotic process GO:0051402 142 0.583
associative learning GO:0008306 61 0.575
sequestering of metal ion GO:0051238 19 0.575
purine nucleoside metabolic process GO:0042278 241 0.574
regulation of hormone levels GO:0010817 211 0.571
regulation of cell motility GO:2000145 236 0.569
ribose phosphate biosynthetic process GO:0046390 59 0.566
blood circulation GO:0008015 195 0.561
negative regulation of phosphate metabolic process GO:0045936 184 0.561
cellular divalent inorganic cation homeostasis GO:0072503 127 0.560
regulation of actin cytoskeleton organization GO:0032956 84 0.558
amide transport GO:0042886 138 0.556
negative regulation of neuron death GO:1901215 98 0.555
lateral geniculate nucleus development GO:0021771 1 0.553
positive regulation of protein phosphorylation GO:0001934 242 0.551
negative regulation of blood pressure GO:0045776 22 0.541
regulation of organelle organization GO:0033043 289 0.541
response to transition metal nanoparticle GO:1990267 11 0.541
Rat
regulation of reactive oxygen species metabolic process GO:2000377 40 0.539
synaptic transmission cholinergic GO:0007271 7 0.538
regulation of action potential GO:0098900 4 0.535
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.535
histamine induced gastric acid secretion GO:0001697 1 0.534
metencephalon development GO:0022037 89 0.530
sequestering of calcium ion GO:0051208 18 0.529
regulation of neuron death GO:1901214 134 0.525
regulation of glutamate secretion GO:0014048 3 0.524
generation of precursor metabolites and energy GO:0006091 103 0.519
gland development GO:0048732 330 0.518
oxidation reduction process GO:0055114 342 0.518
establishment of organelle localization GO:0051656 122 0.516
regulation of protein kinase activity GO:0045859 232 0.509
digestive tract development GO:0048565 190 0.508
regulation of kinase activity GO:0043549 249 0.508
cytokine production GO:0001816 319 0.504
regulation of smooth muscle contraction GO:0006940 22 0.502
substrate independent telencephalic tangential migration GO:0021826 8 0.500
regulation of neuron differentiation GO:0045664 281 0.497
cellular ion homeostasis GO:0006873 165 0.495
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.492
regulation of calcium ion transport GO:0051924 69 0.489
muscle contraction GO:0006936 101 0.479
cellular homeostasis GO:0019725 240 0.479
nucleoside phosphate biosynthetic process GO:1901293 79 0.474
multicellular organismal response to stress GO:0033555 62 0.471
Mouse
operant conditioning GO:0035106 2 0.469
visual behavior GO:0007632 45 0.469
divalent inorganic cation transport GO:0072511 178 0.468
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 5 0.466
organic acid transport GO:0015849 101 0.466
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.464
positive regulation of neurotransmitter transport GO:0051590 9 0.462
regulation of cell division GO:0051302 76 0.460
positive regulation of homeostatic process GO:0032846 64 0.458
regulation of hormone secretion GO:0046883 88 0.457
regulation of response to wounding GO:1903034 189 0.456
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.456
positive regulation of organelle organization GO:0010638 128 0.456
calcium ion transport into cytosol GO:0060402 48 0.454
forebrain neuron differentiation GO:0021879 52 0.453
negative regulation of homeostatic process GO:0032845 71 0.453
regulation of renal sodium excretion GO:0035813 3 0.450
telencephalon cell migration GO:0022029 55 0.436
neurotransmitter secretion GO:0007269 62 0.434
regulation of circadian rhythm GO:0042752 58 0.430
renal sodium excretion GO:0035812 3 0.429
regulation of peptide transport GO:0090087 91 0.425
regulation of metal ion transport GO:0010959 106 0.423
purine ribonucleoside metabolic process GO:0046128 241 0.423
positive regulation of synaptic transmission dopaminergic GO:0032226 5 0.420
b cell proliferation GO:0042100 53 0.416
response to drug GO:0042493 75 0.415
Rat
transmission of nerve impulse GO:0019226 76 0.415
neuronal action potential GO:0019228 54 0.414
negative regulation of purine nucleotide biosynthetic process GO:1900372 6 0.414
fear response GO:0042596 33 0.413
cerebellum development GO:0021549 77 0.410
cation homeostasis GO:0055080 212 0.408
positive regulation of catecholamine uptake involved in synaptic transmission GO:0051944 2 0.408
cellular response to cytokine stimulus GO:0071345 189 0.408
negative regulation of serotonin secretion GO:0014063 2 0.406
cytosolic calcium ion transport GO:0060401 48 0.404
regulation of fat cell differentiation GO:0045598 81 0.403
social behavior GO:0035176 21 0.402
Mouse
response to pain GO:0048265 26 0.401
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.397
somatotropin secreting cell differentiation GO:0060126 4 0.396
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.396
positive regulation of heart rate GO:0010460 10 0.395
fatty acid metabolic process GO:0006631 121 0.394
regulation of cytokine production GO:0001817 266 0.394
negative regulation of organelle organization GO:0010639 90 0.393
alcohol biosynthetic process GO:0046165 43 0.389
alcohol metabolic process GO:0006066 116 0.387
dentate gyrus development GO:0021542 14 0.387
circadian rhythm GO:0007623 114 0.385
circulatory system process GO:0003013 197 0.384
negative regulation of cell proliferation GO:0008285 296 0.384
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.383
small molecule biosynthetic process GO:0044283 132 0.383
phasic smooth muscle contraction GO:0014821 8 0.382
negative regulation of secretion GO:0051048 61 0.381
response to inorganic substance GO:0010035 96 0.378
Rat
regulation of neuron apoptotic process GO:0043523 122 0.377
gabaergic neuron differentiation GO:0097154 11 0.377
peptidyl tyrosine phosphorylation GO:0018108 143 0.376
acetylcholine secretion neurotransmission GO:0014055 2 0.375
regulation of actin filament based process GO:0032970 99 0.375
adenohypophysis development GO:0021984 14 0.372
telencephalon development GO:0021537 186 0.370
purine ribonucleotide biosynthetic process GO:0009152 59 0.370
regulation of peptide secretion GO:0002791 77 0.369
regulation of camp biosynthetic process GO:0030817 25 0.368
regulation of nucleotide metabolic process GO:0006140 169 0.367
peptidyl serine phosphorylation GO:0018105 74 0.364
maintenance of location GO:0051235 89 0.360
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.360
membrane organization GO:0061024 245 0.359
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.359
ribonucleotide metabolic process GO:0009259 291 0.359
synaptic vesicle localization GO:0097479 59 0.358
regulation of lipid metabolic process GO:0019216 118 0.358
sulfur compound biosynthetic process GO:0044272 37 0.354
regulation of amine transport GO:0051952 21 0.354
insulin secretion GO:0030073 89 0.353
peptide transport GO:0015833 133 0.353
endocrine system development GO:0035270 98 0.349
regulation of voltage gated calcium channel activity GO:1901385 4 0.348
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.347
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.345
regulation of cellular component biogenesis GO:0044087 181 0.344
negative regulation of camp biosynthetic process GO:0030818 5 0.344
negative regulation of defense response GO:0031348 77 0.343
habituation GO:0046959 3 0.343
regulation of system process GO:0044057 200 0.343
behavioral response to ethanol GO:0048149 8 0.343
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.341
regulation of feeding behavior GO:0060259 3 0.340
learning GO:0007612 98 0.338
regulation of carbohydrate metabolic process GO:0006109 75 0.335
purine nucleoside triphosphate metabolic process GO:0009144 226 0.335
forebrain generation of neurons GO:0021872 63 0.332
receptor internalization GO:0031623 16 0.331
positive regulation of cell migration GO:0030335 109 0.329
cerebellum morphogenesis GO:0021587 42 0.326
ribonucleoside metabolic process GO:0009119 245 0.325
bone resorption GO:0045453 38 0.323
negative regulation of phosphorus metabolic process GO:0010563 184 0.322
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.322
norepinephrine transport GO:0015874 2 0.321
diencephalon development GO:0021536 63 0.319
negative regulation of inflammatory response GO:0050728 61 0.316
negative regulation of lyase activity GO:0051350 1 0.316
renal system process GO:0003014 48 0.316
positive regulation of cellular catabolic process GO:0031331 148 0.315
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.313
placenta development GO:0001890 140 0.311
camera type eye development GO:0043010 266 0.311
circadian sleep wake cycle non rem sleep GO:0042748 2 0.309
glial cell differentiation GO:0010001 131 0.308
pituitary gland development GO:0021983 38 0.306
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.305
camp biosynthetic process GO:0006171 31 0.305
glycosyl compound metabolic process GO:1901657 246 0.304
rhythmic process GO:0048511 174 0.301
regulation of blood circulation GO:1903522 93 0.299
negative regulation of nucleotide biosynthetic process GO:0030809 6 0.298
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.295
regulation of cell migration GO:0030334 219 0.295
regulation of muscle contraction GO:0006937 49 0.294
forebrain neuron development GO:0021884 30 0.293
regulation of mitochondrial fission GO:0090140 3 0.292
protein targeting GO:0006605 143 0.291
embryonic organ morphogenesis GO:0048562 276 0.290
positive regulation of cell division GO:0051781 31 0.290
activation of adenylate cyclase activity GO:0007190 4 0.287
cellular response to temperature stimulus GO:0071502 2 0.287
negative regulation of cellular amine metabolic process GO:0033239 1 0.285
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.285
negative regulation of neuron apoptotic process GO:0043524 92 0.283
glycerophospholipid metabolic process GO:0006650 71 0.281
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.279
ribose phosphate metabolic process GO:0019693 291 0.279
regulation of peptidyl lysine acetylation GO:2000756 22 0.278
digestive system development GO:0055123 200 0.277
gastrin induced gastric acid secretion GO:0001698 1 0.276
hair follicle morphogenesis GO:0031069 29 0.274
synaptic transmission glutamatergic GO:0035249 36 0.274
positive regulation of proteolysis GO:0045862 85 0.274
catecholamine uptake GO:0090493 4 0.274
actin cytoskeleton organization GO:0030036 220 0.270
positive regulation of calcium ion transport GO:0051928 27 0.269
inflammatory response GO:0006954 244 0.269
hindbrain development GO:0030902 128 0.268
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback GO:0001978 5 0.267
chromatin modification GO:0016568 187 0.267
serotonin receptor signaling pathway GO:0007210 8 0.263
negative regulation of secretion by cell GO:1903531 54 0.262
developmental cell growth GO:0048588 84 0.262
cell growth GO:0016049 130 0.259
nucleoside phosphate metabolic process GO:0006753 338 0.259
muscle system process GO:0003012 141 0.256
neutral lipid metabolic process GO:0006638 57 0.255
midbrain development GO:0030901 35 0.255
carbohydrate biosynthetic process GO:0016051 74 0.255
carbohydrate homeostasis GO:0033500 128 0.252
nucleobase containing small molecule metabolic process GO:0055086 352 0.252
response to decreased oxygen levels GO:0036293 59 0.251
negative regulation of molecular function GO:0044092 258 0.249
long term synaptic depression GO:0060292 13 0.249
asymmetric stem cell division GO:0098722 3 0.249
regulation of norepinephrine secretion GO:0014061 2 0.248
lymphocyte proliferation GO:0046651 164 0.248
regulation of protein complex assembly GO:0043254 83 0.247
multicellular organismal homeostasis GO:0048871 164 0.246
behavioral fear response GO:0001662 28 0.245
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.243
negative regulation of growth GO:0045926 99 0.243
Mouse
histone acetylation GO:0016573 41 0.243
regulation of homeostatic process GO:0032844 182 0.242
regulation of heart rate GO:0002027 36 0.241
endocytosis GO:0006897 168 0.240
camp metabolic process GO:0046058 40 0.238
peptidyl lysine modification GO:0018205 77 0.238
regulation of cellular response to oxidative stress GO:1900407 19 0.237
peptidyl serine modification GO:0018209 83 0.237
regulation of response to oxidative stress GO:1902882 19 0.237
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.236
subpallium development GO:0021544 20 0.234
glutamate secretion GO:0014047 8 0.234
negative regulation of transporter activity GO:0032410 7 0.233
cation transmembrane transport GO:0098655 266 0.233
positive regulation of growth hormone secretion GO:0060124 3 0.233
regulation of multi organism process GO:0043900 111 0.232
cyclic purine nucleotide metabolic process GO:0052652 43 0.230
cellular response to oxidative stress GO:0034599 76 0.230
positive regulation of carbohydrate metabolic process GO:0045913 30 0.229
vesicle localization GO:0051648 86 0.228
positive regulation of growth GO:0045927 104 0.227
reactive oxygen species metabolic process GO:0072593 84 0.227
chemotaxis GO:0006935 247 0.226
acetylcholine transport GO:0015870 2 0.225
regulation of transmembrane transport GO:0034762 128 0.225
embryonic placenta development GO:0001892 98 0.224
protein localization to organelle GO:0033365 185 0.220
negative regulation of cytoskeleton organization GO:0051494 36 0.219
somatostatin receptor signaling pathway GO:0038169 2 0.217
protein localization to nucleus GO:0034504 121 0.216
regulation of peptidyl serine phosphorylation GO:0033135 39 0.216
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.215
regulation of long term synaptic potentiation GO:1900271 4 0.215
purine containing compound metabolic process GO:0072521 311 0.214
protein import into nucleus GO:0006606 95 0.214
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.214
protein polymerization GO:0051258 57 0.212
blood vessel morphogenesis GO:0048514 285 0.212
response to alcohol GO:0097305 48 0.211
Rat
neuron projection extension GO:1990138 64 0.211
regulation of glucose metabolic process GO:0010906 60 0.208
sensitization GO:0046960 2 0.208
cerebral cortex neuron differentiation GO:0021895 19 0.207
positive regulation of programmed cell death GO:0043068 218 0.207
central nervous system neuron development GO:0021954 67 0.206
positive regulation of lymphocyte proliferation GO:0050671 70 0.205
positive regulation of cytokine production GO:0001819 174 0.205
extracellular matrix organization GO:0030198 147 0.204
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.204
cell proliferation in external granule layer GO:0021924 10 0.203
ameboidal type cell migration GO:0001667 128 0.202
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 5 0.202
cytoplasmic transport GO:0016482 234 0.202
regulation of interleukin 1 beta production GO:0032651 25 0.201
labyrinthine layer blood vessel development GO:0060716 21 0.200
regulation of acyl coa biosynthetic process GO:0050812 4 0.200
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.199
positive regulation of nucleotide metabolic process GO:0045981 114 0.199
brown fat cell differentiation GO:0050873 36 0.198
regulation of cellular catabolic process GO:0031329 242 0.197
regulation of cellular response to stress GO:0080135 159 0.196
regulation of leukocyte proliferation GO:0070663 121 0.196
nucleoside monophosphate metabolic process GO:0009123 85 0.193
multi organism behavior GO:0051705 62 0.193
Mouse
aromatic compound catabolic process GO:0019439 286 0.192
nucleotide metabolic process GO:0009117 332 0.192
positive regulation of nervous system development GO:0051962 221 0.191
response to oxygen levels GO:0070482 62 0.191
second messenger mediated signaling GO:0019932 73 0.189
regulation of heart contraction GO:0008016 77 0.189
regulation of systemic arterial blood pressure by baroreceptor feedback GO:0003025 7 0.189
dicarboxylic acid transport GO:0006835 29 0.188
peristalsis GO:0030432 8 0.188
regulation of cell cycle GO:0051726 281 0.187
Mouse
multicellular organism growth GO:0035264 161 0.187
regulation of lymphocyte proliferation GO:0050670 117 0.186
asymmetric neuroblast division GO:0055059 1 0.186
circadian behavior GO:0048512 13 0.186
neuromuscular synaptic transmission GO:0007274 16 0.186
positive regulation of calcium ion transport into cytosol GO:0010524 9 0.186
regulation of cell activation GO:0050865 289 0.186
glycerolipid metabolic process GO:0046486 122 0.185
regulation of muscle system process GO:0090257 80 0.185
somatostatin signaling pathway GO:0038170 2 0.184
response to steroid hormone GO:0048545 56 0.183
placenta blood vessel development GO:0060674 31 0.183
inositol phosphate biosynthetic process GO:0032958 6 0.183
detection of mechanical stimulus GO:0050982 27 0.180
positive regulation of heart contraction GO:0045823 14 0.180
regulation of transporter activity GO:0032409 57 0.180
nuclear transport GO:0051169 139 0.178
regulation of defense response GO:0031347 233 0.177
positive regulation of cell development GO:0010720 237 0.176
polyol metabolic process GO:0019751 26 0.176
cellular protein complex assembly GO:0043623 116 0.176
microglial cell activation GO:0001774 3 0.175
sensory perception GO:0007600 245 0.174
regulation of b cell proliferation GO:0030888 39 0.172
positive regulation of glycolytic process GO:0045821 4 0.172
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.171
response to food GO:0032094 17 0.169
monosaccharide metabolic process GO:0005996 106 0.169
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.169

Slc6a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.195
disease of anatomical entity DOID:7 0 0.195
neurodegenerative disease DOID:1289 0 0.195
nervous system disease DOID:863 0 0.195