Mus musculus

0 known processes

Hax1

HCLS1 associated X-1

(Aliases: HAX-1,SIG-111,mHAX-1s,Hs1bp1,Silg111)

Hax1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.131
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.084
nuclear division GO:0000280 158 0.082
lymphocyte differentiation GO:0030098 242 0.074
leukocyte differentiation GO:0002521 342 0.071
Human
cellular amino acid metabolic process GO:0006520 103 0.070
modification dependent macromolecule catabolic process GO:0043632 133 0.064
t cell differentiation GO:0030217 174 0.050
cellular homeostasis GO:0019725 240 0.049
t cell activation GO:0042110 289 0.047
organelle fission GO:0048285 170 0.045
modification dependent protein catabolic process GO:0019941 133 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
proteasome assembly GO:0043248 1 0.042
organic cyclic compound catabolic process GO:1901361 295 0.042
sensory organ morphogenesis GO:0090596 242 0.041
lateral inhibition GO:0046331 1 0.040
cellular protein catabolic process GO:0044257 155 0.040
proteasomal protein catabolic process GO:0010498 98 0.038
regulation of transferase activity GO:0051338 263 0.038
skeletal system development GO:0001501 356 0.037
regulation of protein kinase activity GO:0045859 232 0.037
gland development GO:0048732 330 0.035
ubiquitin dependent protein catabolic process GO:0006511 129 0.035
cellular macromolecule catabolic process GO:0044265 206 0.034
cytokine production GO:0001816 319 0.034
cellular protein complex assembly GO:0043623 116 0.034
Human
purine containing compound metabolic process GO:0072521 311 0.033
regulation of cell cycle GO:0051726 281 0.032
carboxylic acid biosynthetic process GO:0046394 86 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
macromolecule catabolic process GO:0009057 281 0.030
response to organonitrogen compound GO:0010243 246 0.030
regulation of lymphocyte activation GO:0051249 240 0.030
organelle assembly GO:0070925 177 0.030
regulation of cell activation GO:0050865 289 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
regulation of t cell activation GO:0050863 170 0.029
regulation of membrane potential GO:0042391 192 0.029
regulation of organelle organization GO:0033043 289 0.028
Human
apoptotic signaling pathway GO:0097190 306 0.027
mapk cascade GO:0000165 281 0.027
spermatogenesis GO:0007283 284 0.027
trna metabolic process GO:0006399 11 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
regulation of leukocyte differentiation GO:1902105 159 0.027
Human
regulation of kinase activity GO:0043549 249 0.026
methylation GO:0032259 134 0.026
response to acid chemical GO:0001101 111 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
regulation of mapk cascade GO:0043408 248 0.024
leukocyte proliferation GO:0070661 172 0.024
cellular response to lipid GO:0071396 145 0.024
protein import GO:0017038 101 0.024
organic acid biosynthetic process GO:0016053 86 0.024
negative regulation of molecular function GO:0044092 258 0.023
ion transmembrane transport GO:0034220 361 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.022
i kappab kinase nf kappab signaling GO:0007249 85 0.022
amine metabolic process GO:0009308 45 0.022
positive regulation of protein modification process GO:0031401 299 0.022
Human
negative regulation of protein metabolic process GO:0051248 282 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
aromatic compound catabolic process GO:0019439 286 0.022
organophosphate catabolic process GO:0046434 232 0.022
stem cell differentiation GO:0048863 268 0.022
leukocyte migration GO:0050900 124 0.022
cellular chemical homeostasis GO:0055082 215 0.021
protein maturation GO:0051604 176 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
cell division GO:0051301 120 0.021
leukocyte mediated immunity GO:0002443 174 0.021
cation transport GO:0006812 399 0.021
male gamete generation GO:0048232 285 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
regulation of cellular response to stress GO:0080135 159 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
myeloid cell differentiation GO:0030099 233 0.020
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of cell cycle process GO:0010564 160 0.020
negative regulation of cell development GO:0010721 169 0.020
cation transmembrane transport GO:0098655 266 0.020
cellular response to biotic stimulus GO:0071216 92 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
embryonic organ morphogenesis GO:0048562 276 0.019
extracellular matrix organization GO:0030198 147 0.019
camera type eye development GO:0043010 266 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
wnt signaling pathway GO:0016055 188 0.019
cell type specific apoptotic process GO:0097285 268 0.019
protein catabolic process GO:0030163 221 0.019
protein folding GO:0006457 28 0.019
extracellular structure organization GO:0043062 148 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
pyridine containing compound catabolic process GO:0072526 4 0.018
cell growth GO:0016049 130 0.018
nuclear import GO:0051170 95 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
nucleoside metabolic process GO:0009116 246 0.018
protein localization to organelle GO:0033365 185 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.018
metal ion homeostasis GO:0055065 189 0.018
immune response regulating signaling pathway GO:0002764 125 0.018
synaptic transmission GO:0007268 329 0.017
mitotic cell cycle process GO:1903047 159 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.017
chromatin modification GO:0016568 187 0.017
divalent inorganic cation transport GO:0072511 178 0.017
lymphocyte proliferation GO:0046651 164 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
gonad development GO:0008406 141 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
Human
carbohydrate derivative catabolic process GO:1901136 231 0.017
neuron apoptotic process GO:0051402 142 0.017
regulation of multi organism process GO:0043900 111 0.017
regulation of ion transport GO:0043269 215 0.017
organophosphate biosynthetic process GO:0090407 122 0.016
glycerolipid metabolic process GO:0046486 122 0.016
connective tissue development GO:0061448 179 0.016
calcium ion transport GO:0006816 159 0.016
heterocycle catabolic process GO:0046700 280 0.016
regulation of t cell differentiation GO:0045580 83 0.016
t cell proliferation GO:0042098 120 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
membrane lipid metabolic process GO:0006643 53 0.016
cellular ion homeostasis GO:0006873 165 0.016
mitotic cell cycle GO:0000278 195 0.016
regulation of systemic arterial blood pressure GO:0003073 61 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
Human
positive regulation of protein kinase activity GO:0045860 144 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
nucleotide metabolic process GO:0009117 332 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
neuron death GO:0070997 154 0.015
positive regulation of protein catabolic process GO:0045732 60 0.015
cellular ketone metabolic process GO:0042180 84 0.015
blastocyst development GO:0001824 80 0.015
protein localization to nucleus GO:0034504 121 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
cellular amine metabolic process GO:0044106 44 0.015
nitrogen compound transport GO:0071705 271 0.015
microtubule based process GO:0007017 236 0.015
positive regulation of transferase activity GO:0051347 167 0.014
regulation of neuron differentiation GO:0045664 281 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
Human
cellular lipid metabolic process GO:0044255 323 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
dna metabolic process GO:0006259 303 0.014
transmembrane transport GO:0055085 412 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
respiratory system development GO:0060541 190 0.014
intracellular protein transport GO:0006886 204 0.014
fertilization GO:0009566 127 0.014
sensory perception GO:0007600 245 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
regulation of protein localization GO:0032880 231 0.014
b cell activation GO:0042113 161 0.014
calcium ion homeostasis GO:0055074 127 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.013
Human
peptidyl amino acid modification GO:0018193 336 0.013
Human
purine ribonucleoside catabolic process GO:0046130 205 0.013
regulation of hormone levels GO:0010817 211 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
circulatory system process GO:0003013 197 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
muscle tissue development GO:0060537 308 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
cation homeostasis GO:0055080 212 0.013
regulation of anatomical structure size GO:0090066 178 0.013
Human
rna processing GO:0006396 105 0.013
mitotic cytokinesis GO:0000281 4 0.013
rna catabolic process GO:0006401 29 0.013
regulation of cytokine production GO:0001817 266 0.012
negative regulation of protein modification process GO:0031400 163 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of homeostatic process GO:0032844 182 0.012
skeletal system morphogenesis GO:0048705 203 0.012
peptide transport GO:0015833 133 0.012
response to peptide GO:1901652 136 0.012
protein ubiquitination GO:0016567 171 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
respiratory tube development GO:0030323 167 0.012
hindbrain development GO:0030902 128 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
rhythmic process GO:0048511 174 0.012
positive regulation of cell cycle GO:0045787 92 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
alpha beta t cell activation GO:0046631 91 0.012
regulation of cell migration GO:0030334 219 0.012
positive regulation of kinase activity GO:0033674 155 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
positive regulation of hydrolase activity GO:0051345 148 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
purine containing compound catabolic process GO:0072523 213 0.011
response to lipopolysaccharide GO:0032496 128 0.011
spindle assembly involved in mitosis GO:0090307 4 0.011
membrane organization GO:0061024 245 0.011
macromolecule methylation GO:0043414 120 0.011
epidermis development GO:0008544 187 0.011
striated muscle tissue development GO:0014706 293 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
protein import into nucleus GO:0006606 95 0.011
ossification GO:0001503 216 0.011
response to topologically incorrect protein GO:0035966 25 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
cell fate commitment GO:0045165 210 0.011
chromatin organization GO:0006325 206 0.011
muscle cell differentiation GO:0042692 261 0.011
regulation of cell division GO:0051302 76 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of chromosome organization GO:0033044 83 0.011
stress activated mapk cascade GO:0051403 80 0.011
regulation of map kinase activity GO:0043405 120 0.011
regulation of cell projection organization GO:0031344 206 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
positive regulation of organelle organization GO:0010638 128 0.011
Human
stem cell development GO:0048864 219 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
activation of immune response GO:0002253 138 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
maintenance of location GO:0051235 89 0.010
amide transport GO:0042886 138 0.010
regulation of response to dna damage stimulus GO:2001020 34 0.010
positive regulation of cell activation GO:0050867 158 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
neuromuscular process GO:0050905 99 0.010
regulation of cell motility GO:2000145 236 0.010
regulation of protein transport GO:0051223 163 0.010

Hax1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
Human
nervous system disease DOID:863 0 0.040
central nervous system disease DOID:331 0 0.019
primary immunodeficiency disease DOID:612 0 0.010
immune system disease DOID:2914 0 0.010
Human