Mus musculus

13 known processes

Irx4

Iroquois related homeobox 4 (Drosophila)

Irx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 276 0.638
embryonic placenta development GO:0001892 98 0.548
regulation of cellular ketone metabolic process GO:0010565 66 0.530
camera type eye development GO:0043010 266 0.474
Mouse
amine metabolic process GO:0009308 45 0.469
muscle cell differentiation GO:0042692 261 0.460
Mouse
regulation of body fluid levels GO:0050878 162 0.455
regionalization GO:0003002 337 0.432
Mouse
cellular ketone metabolic process GO:0042180 84 0.426
blood vessel morphogenesis GO:0048514 285 0.426
placenta development GO:0001890 140 0.388
epithelial tube morphogenesis GO:0060562 303 0.382
Mouse
regulation of heart contraction GO:0008016 77 0.371
Mouse
stem cell development GO:0048864 219 0.363
cell type specific apoptotic process GO:0097285 268 0.353
bmp signaling pathway GO:0030509 93 0.347
regulation of neuron differentiation GO:0045664 281 0.345
Mouse
heart contraction GO:0060047 93 0.345
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.334
cell fate commitment GO:0045165 210 0.322
mesenchymal cell development GO:0014031 93 0.309
embryonic epithelial tube formation GO:0001838 130 0.302
Mouse
positive regulation of nervous system development GO:0051962 221 0.295
Mouse
ear development GO:0043583 200 0.294
stem cell differentiation GO:0048863 268 0.289
gland development GO:0048732 330 0.275
limb development GO:0060173 166 0.271
sensory organ morphogenesis GO:0090596 242 0.268
Mouse
cardiac chamber development GO:0003205 108 0.264
keratinocyte differentiation GO:0030216 48 0.259
striated muscle tissue development GO:0014706 293 0.259
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.247
muscle tissue development GO:0060537 308 0.239
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.237
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.231
positive regulation of neuron differentiation GO:0045666 141 0.214
Mouse
regulation of muscle tissue development GO:1901861 97 0.213
Mouse
cellular amino acid metabolic process GO:0006520 103 0.212
cellular amine metabolic process GO:0044106 44 0.211
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.206
regulation of system process GO:0044057 200 0.203
Mouse
cardiac ventricle development GO:0003231 83 0.200
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.185
primary neural tube formation GO:0014020 95 0.181
neuron projection guidance GO:0097485 141 0.180
cardiocyte differentiation GO:0035051 87 0.180
regulation of organ morphogenesis GO:2000027 144 0.178
embryonic heart tube morphogenesis GO:0003143 51 0.177
regulation of ras gtpase activity GO:0032318 88 0.175
forebrain neuron differentiation GO:0021879 52 0.173
negative regulation of testosterone biosynthetic process GO:2000225 1 0.171
chemotaxis GO:0006935 247 0.170
axonogenesis GO:0007409 274 0.169
tube formation GO:0035148 140 0.167
Mouse
positive regulation of cell development GO:0010720 237 0.165
Mouse
central nervous system neuron differentiation GO:0021953 162 0.161
appendage development GO:0048736 166 0.160
skin development GO:0043588 220 0.159
Zebrafish
apoptotic signaling pathway GO:0097190 306 0.159
negative regulation of cell proliferation GO:0008285 296 0.158
inner ear morphogenesis GO:0042472 101 0.154
mammary gland epithelium development GO:0061180 65 0.153
paraxial mesodermal cell differentiation GO:0048342 2 0.153
somatotropin secreting cell differentiation GO:0060126 4 0.152
lymphocyte differentiation GO:0030098 242 0.151
heart morphogenesis GO:0003007 178 0.151
nucleotide catabolic process GO:0009166 217 0.149
neural tube closure GO:0001843 90 0.147
gtp catabolic process GO:0006184 143 0.146
forebrain development GO:0030900 302 0.145
mesenchyme development GO:0060485 152 0.145
small gtpase mediated signal transduction GO:0007264 97 0.143
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.140
renal outer medulla development GO:0072054 2 0.137
appendage morphogenesis GO:0035107 149 0.135
synapse organization GO:0050808 125 0.135
positive regulation of protein modification process GO:0031401 299 0.133
epidermis development GO:0008544 187 0.132
Zebrafish
head morphogenesis GO:0060323 34 0.132
ventricular cardiac muscle cell action potential GO:0086005 4 0.131
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.129
regulation of cell projection organization GO:0031344 206 0.128
uterus morphogenesis GO:0061038 2 0.127
nucleoside phosphate metabolic process GO:0006753 338 0.127
skeletal muscle fiber development GO:0048741 58 0.127
Mouse
cerebral cortex development GO:0021987 86 0.126
circulatory system process GO:0003013 197 0.125
Mouse
regulation of gtp catabolic process GO:0033124 113 0.125
ossification GO:0001503 216 0.124
developmental maturation GO:0021700 193 0.123
Mouse
cardiac muscle tissue development GO:0048738 130 0.123
leukocyte differentiation GO:0002521 342 0.123
hair follicle development GO:0001942 85 0.123
nucleobase containing small molecule metabolic process GO:0055086 352 0.122
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.122
gas homeostasis GO:0033483 3 0.122
organ growth GO:0035265 117 0.122
rho protein signal transduction GO:0007266 32 0.120
dendrite development GO:0016358 115 0.120
regulation of asymmetric cell division GO:0009786 4 0.120
regulation of secretion GO:0051046 274 0.119
wnt signaling pathway GO:0016055 188 0.119
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.118
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.118
heart process GO:0003015 94 0.116
Mouse
mesoderm formation GO:0001707 62 0.116
olfactory bulb development GO:0021772 30 0.115
paramesonephric duct development GO:0061205 3 0.114
epithelial cell proliferation GO:0050673 174 0.114
morphogenesis of a branching structure GO:0001763 203 0.113
muscle system process GO:0003012 141 0.113
purine ribonucleotide metabolic process GO:0009150 290 0.113
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.112
pigmentation GO:0043473 71 0.112
urogenital system development GO:0001655 261 0.111
Mouse
regulation of cell cycle GO:0051726 281 0.110
neural tube development GO:0021915 160 0.110
neural retina development GO:0003407 41 0.110
Mouse
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.108
central nervous system vasculogenesis GO:0022009 3 0.108
canonical wnt signaling pathway GO:0060070 130 0.107
regulation of cellular amino acid metabolic process GO:0006521 5 0.107
mesonephric duct formation GO:0072181 2 0.106
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.106
response to parathyroid hormone GO:0071107 3 0.106
embryonic limb morphogenesis GO:0030326 126 0.105
regulation of nucleotide metabolic process GO:0006140 169 0.105
oxygen homeostasis GO:0032364 2 0.105
positive regulation of anagen GO:0051885 1 0.105
mammary gland duct morphogenesis GO:0060603 38 0.104
oviduct development GO:0060066 3 0.104
tube closure GO:0060606 91 0.103
aortic valve morphogenesis GO:0003180 4 0.102
cellular response to growth factor stimulus GO:0071363 197 0.102
regulation of ras protein signal transduction GO:0046578 114 0.102
neural tube formation GO:0001841 108 0.101
myeloid cell differentiation GO:0030099 233 0.101
autonomic nervous system development GO:0048483 43 0.100
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.100
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.098
positive regulation of interleukin 8 secretion GO:2000484 1 0.098
spemann organizer formation GO:0060061 2 0.098
cerebellum formation GO:0021588 1 0.098
single organismal cell cell adhesion GO:0016337 131 0.098
embryonic heart tube development GO:0035050 65 0.098
regulation of anagen GO:0051884 1 0.097
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.097
skeletal system development GO:0001501 356 0.097
regulation of protein transport GO:0051223 163 0.096
midbrain hindbrain boundary maturation GO:0021732 1 0.096
photoreceptor cell development GO:0042461 40 0.096
Zebrafish
central nervous system morphogenesis GO:0021551 2 0.096
muscle cell development GO:0055001 133 0.095
Mouse
ventricular septum development GO:0003281 42 0.095
artery development GO:0060840 53 0.095
cell differentiation in spinal cord GO:0021515 53 0.094
epithelial cell morphogenesis GO:0003382 41 0.094
axis elongation involved in somitogenesis GO:0090245 4 0.094
cell differentiation involved in embryonic placenta development GO:0060706 26 0.094
regulation of transforming growth factor beta2 production GO:0032909 2 0.093
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.093
ear morphogenesis GO:0042471 118 0.092
diencephalon development GO:0021536 63 0.092
mesonephric duct morphogenesis GO:0072180 4 0.092
renal system development GO:0072001 225 0.092
Mouse
lung induction GO:0060492 3 0.092
mesoderm morphogenesis GO:0048332 64 0.092
establishment or maintenance of cell polarity GO:0007163 86 0.091
positive regulation of cellular amine metabolic process GO:0033240 5 0.091
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.091
regulation of heart rate GO:0002027 36 0.091
Mouse
auditory receptor cell fate specification GO:0042667 1 0.091
negative regulation of cellular amine metabolic process GO:0033239 1 0.091
negative regulation of cytokine production GO:0001818 84 0.090
skeletal muscle organ development GO:0060538 163 0.090
Mouse
outflow tract morphogenesis GO:0003151 53 0.090
cervix development GO:0060067 2 0.089
regulation of ossification GO:0030278 112 0.089
regulation of bmp signaling pathway GO:0030510 60 0.089
spinal cord development GO:0021510 81 0.089
synaptic transmission GO:0007268 329 0.089
Worm
formation of primary germ layer GO:0001704 77 0.089
pancreatic a cell fate commitment GO:0003326 2 0.088
telencephalon development GO:0021537 186 0.088
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.087
mesenchymal cell differentiation GO:0048762 107 0.087
purine containing compound catabolic process GO:0072523 213 0.086
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.086
water homeostasis GO:0030104 27 0.086
neuron migration GO:0001764 122 0.086
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.086
striated muscle cell development GO:0055002 125 0.085
Mouse
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.085
ras protein signal transduction GO:0007265 77 0.085
regulation of response to wounding GO:1903034 189 0.085
digestive tract morphogenesis GO:0048546 147 0.085
regulation of establishment of protein localization GO:0070201 181 0.083
asymmetric neuroblast division GO:0055059 1 0.083
hindbrain formation GO:0021576 1 0.083
nephron development GO:0072006 109 0.082
Mouse
asymmetric stem cell division GO:0098722 3 0.082
cardiac septum development GO:0003279 59 0.082
paraxial mesodermal cell fate commitment GO:0048343 2 0.082
negative regulation of molecular function GO:0044092 258 0.081
endocrine system development GO:0035270 98 0.081
establishment of organ orientation GO:0048561 1 0.079
nephric duct formation GO:0072179 4 0.079
hematopoietic progenitor cell differentiation GO:0002244 143 0.079
ventricular septum morphogenesis GO:0060412 27 0.079
guanosine containing compound catabolic process GO:1901069 144 0.078
regulation of purine nucleotide catabolic process GO:0033121 122 0.078
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.078
epithelial to mesenchymal transition GO:0001837 47 0.078
metanephric loop of henle development GO:0072236 4 0.078
fat cell differentiation GO:0045444 160 0.078
digestive system development GO:0055123 200 0.077
olfactory lobe development GO:0021988 32 0.077
trophoblast giant cell differentiation GO:0060707 15 0.077
ribonucleoside metabolic process GO:0009119 245 0.077
heterocycle catabolic process GO:0046700 280 0.076
purine nucleotide metabolic process GO:0006163 302 0.076
hypophysis morphogenesis GO:0048850 3 0.076
mitotic cell cycle process GO:1903047 159 0.076
potassium ion homeostasis GO:0055075 4 0.075
hindbrain development GO:0030902 128 0.074
regulation of ion transport GO:0043269 215 0.074
regulation of rho gtpase activity GO:0032319 58 0.074
bone development GO:0060348 120 0.074
skin morphogenesis GO:0043589 38 0.074
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.074
regulation of nucleoside metabolic process GO:0009118 130 0.074
regulation of homeostatic process GO:0032844 182 0.073
cellular nitrogen compound catabolic process GO:0044270 280 0.073
renal vesicle induction GO:0072034 3 0.073
organic cyclic compound catabolic process GO:1901361 295 0.072
endocardial cushion morphogenesis GO:0003203 18 0.072
skeletal muscle cell differentiation GO:0035914 66 0.072
morphogenesis of a polarized epithelium GO:0001738 37 0.072
ribonucleoside triphosphate catabolic process GO:0009203 199 0.072
branching morphogenesis of an epithelial tube GO:0048754 159 0.071
lens development in camera type eye GO:0002088 62 0.071
developmental growth involved in morphogenesis GO:0060560 138 0.071
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.071
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.071
intermediate filament based process GO:0045103 27 0.070
cardiac epithelial to mesenchymal transition GO:0060317 18 0.070
regulation of purine nucleotide metabolic process GO:1900542 169 0.070
blood circulation GO:0008015 195 0.070
Mouse
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.070
connective tissue development GO:0061448 179 0.070
Mouse
epithelial cell development GO:0002064 159 0.069
trigeminal nerve development GO:0021559 10 0.069
molting cycle GO:0042303 90 0.069
ribose phosphate metabolic process GO:0019693 291 0.069
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.069
visceral serous pericardium development GO:0061032 2 0.069
purine nucleoside catabolic process GO:0006152 205 0.069
maintenance of cell number GO:0098727 3 0.068
myotube differentiation GO:0014902 105 0.068
Mouse
determination of heart left right asymmetry GO:0061371 48 0.068
stem cell maintenance GO:0019827 130 0.068
small molecule biosynthetic process GO:0044283 132 0.068
peptidyl amino acid modification GO:0018193 336 0.068
negative regulation of cellular component organization GO:0051129 194 0.068
lung field specification GO:0060424 3 0.067
cell adhesion GO:0007155 329 0.067
positive regulation of muscle tissue development GO:1901863 32 0.067
mitral valve development GO:0003174 4 0.067
embryonic digit morphogenesis GO:0042733 56 0.067
septum primum development GO:0003284 4 0.066
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.066
embryonic appendage morphogenesis GO:0035113 126 0.066
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.066
epithelial tube formation GO:0072175 130 0.066
Mouse
ribonucleotide metabolic process GO:0009259 291 0.066
sensory perception of light stimulus GO:0050953 54 0.065
regulation of organelle organization GO:0033043 289 0.065
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.065
peripheral nervous system neuron axonogenesis GO:0048936 3 0.065
angiogenesis GO:0001525 201 0.065
protein secretion GO:0009306 111 0.065
regulation of cardiac muscle tissue development GO:0055024 31 0.065
negative regulation of protein metabolic process GO:0051248 282 0.065
limb morphogenesis GO:0035108 149 0.064
regulation of protein localization GO:0032880 231 0.064
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.064
epithelial cell migration GO:0010631 63 0.064
establishment of anatomical structure orientation GO:0048560 1 0.064
digestive tract development GO:0048565 190 0.063
regulation of hydrolase activity GO:0051336 246 0.063
metanephros development GO:0001656 79 0.063
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.063
circadian rhythm GO:0007623 114 0.063
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.063
regulation of canonical wnt signaling pathway GO:0060828 82 0.063
purine nucleoside metabolic process GO:0042278 241 0.063
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.063
positive regulation of striated muscle tissue development GO:0045844 31 0.062
chromatin organization GO:0006325 206 0.062
neuron apoptotic process GO:0051402 142 0.062
morphogenesis of a branching epithelium GO:0061138 193 0.062
sensory perception GO:0007600 245 0.062
renal inner medulla development GO:0072053 3 0.062
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.062
regulation of testosterone biosynthetic process GO:2000224 2 0.061
av node cell to bundle of his cell communication GO:0086067 2 0.061
regulation of cellular catabolic process GO:0031329 242 0.061
tendon formation GO:0035992 4 0.061
Mouse
regulation of cardiac muscle cell proliferation GO:0060043 23 0.061
hemangioblast cell differentiation GO:0060217 1 0.061
forebrain neuron fate commitment GO:0021877 13 0.060
regulation of epidermis development GO:0045682 33 0.060
axon guidance GO:0007411 141 0.060
macromolecule catabolic process GO:0009057 281 0.060
regulation of cardiac muscle tissue growth GO:0055021 26 0.060
negative regulation of bmp signaling pathway GO:0030514 35 0.060
mapk cascade GO:0000165 281 0.059
transdifferentiation GO:0060290 1 0.059
negative regulation of neuron differentiation GO:0045665 101 0.059
Mouse
neural crest cell differentiation GO:0014033 54 0.059
protein processing GO:0016485 163 0.058
gastrulation GO:0007369 116 0.058
regulation of cell motility GO:2000145 236 0.058
mitral valve morphogenesis GO:0003183 4 0.058
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.057
nephron tubule formation GO:0072079 20 0.057
Mouse
skeletal system morphogenesis GO:0048705 203 0.057
negative regulation of cellular protein metabolic process GO:0032269 247 0.057
positive regulation of keratinocyte proliferation GO:0010838 4 0.057
regulation of cytokine production GO:0001817 266 0.057
gonad development GO:0008406 141 0.056
mammary gland epithelial cell proliferation GO:0033598 24 0.056
regulation of neuron death GO:1901214 134 0.056
renal tubule development GO:0061326 87 0.056
Mouse
outer medullary collecting duct development GO:0072060 1 0.056
segmentation GO:0035282 93 0.056
Mouse
negative regulation of immune system process GO:0002683 209 0.056
forebrain regionalization GO:0021871 25 0.055
guanosine containing compound metabolic process GO:1901068 144 0.055
forelimb morphogenesis GO:0035136 40 0.055
mitotic cell cycle GO:0000278 195 0.055
neural precursor cell proliferation GO:0061351 121 0.055
negative regulation of cell development GO:0010721 169 0.055
Mouse
cardiac septum morphogenesis GO:0060411 46 0.054
astrocyte fate commitment GO:0060018 4 0.054
cation transmembrane transport GO:0098655 266 0.054
regulation of fibroblast growth factor production GO:0090270 4 0.054
nucleotide metabolic process GO:0009117 332 0.053
regulation of actin filament based process GO:0032970 99 0.053
negative chemotaxis GO:0050919 14 0.053
cranial nerve development GO:0021545 41 0.053
mechanoreceptor differentiation GO:0042490 67 0.053
Zebrafish
determination of left right symmetry GO:0007368 80 0.053
regulation of cell activation GO:0050865 289 0.052
negative regulation of alcohol biosynthetic process GO:1902931 4 0.052
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.052
ion transmembrane transport GO:0034220 361 0.052
polarity specification of proximal distal axis GO:0010085 2 0.052
posttranscriptional regulation of gene expression GO:0010608 155 0.052
sinoatrial node cell differentiation GO:0060921 3 0.052
ameboidal type cell migration GO:0001667 128 0.052
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.051
t cell differentiation GO:0030217 174 0.051
establishment of tissue polarity GO:0007164 28 0.051
divalent inorganic cation transport GO:0072511 178 0.051
regulation of ketone biosynthetic process GO:0010566 2 0.051
hair cycle GO:0042633 90 0.051
pattern specification involved in metanephros development GO:0072268 4 0.051
Mouse
lateral inhibition GO:0046331 1 0.051
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.051
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.050
endomembrane system organization GO:0010256 147 0.050
inorganic ion transmembrane transport GO:0098660 234 0.050
cellular response to parathyroid hormone stimulus GO:0071374 2 0.050
negative regulation of nervous system development GO:0051961 156 0.050
Mouse
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.050
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.050
cell fate specification GO:0001708 72 0.050
regulation of cell adhesion GO:0030155 154 0.049
aromatic compound catabolic process GO:0019439 286 0.049
cerebellar cortex development GO:0021695 48 0.049
regulation of neuron apoptotic process GO:0043523 122 0.049
metencephalon development GO:0022037 89 0.049
cell proliferation involved in heart valve development GO:2000793 2 0.049
regulation of binding GO:0051098 111 0.049
negative regulation of hydrolase activity GO:0051346 71 0.049
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.049
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.049
photoreceptor cell differentiation GO:0046530 52 0.048
Zebrafish
cardiac muscle cell differentiation GO:0055007 69 0.048
megakaryocyte differentiation GO:0030219 26 0.048
establishment of endothelial blood brain barrier GO:0014045 3 0.048
multi multicellular organism process GO:0044706 109 0.048
regulation of epithelial cell proliferation GO:0050678 141 0.048
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.048
regulation of auditory receptor cell differentiation GO:0045607 4 0.047
regulation of cellular component biogenesis GO:0044087 181 0.047
negative regulation of muscle cell differentiation GO:0051148 33 0.047
Mouse
neuromuscular process GO:0050905 99 0.047
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.047
regulation of interleukin 8 secretion GO:2000482 2 0.047
organonitrogen compound catabolic process GO:1901565 264 0.047
positive regulation of programmed cell death GO:0043068 218 0.047
positive regulation of heart growth GO:0060421 18 0.046
cardiac atrium development GO:0003230 24 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.046
neuron fate specification GO:0048665 30 0.046
tongue development GO:0043586 18 0.045
stem cell proliferation GO:0072089 117 0.045
regulation of secretion by cell GO:1903530 249 0.045
neuron death GO:0070997 154 0.045
cation homeostasis GO:0055080 212 0.044
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.044
cranial nerve morphogenesis GO:0021602 26 0.044
negative regulation of defense response GO:0031348 77 0.044
cochlea morphogenesis GO:0090103 22 0.044
establishment of planar polarity GO:0001736 28 0.044
transmission of nerve impulse GO:0019226 76 0.044
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.044
sclerotome development GO:0061056 4 0.044
histone modification GO:0016570 159 0.044
organophosphate catabolic process GO:0046434 232 0.044
negative regulation of apoptotic signaling pathway GO:2001234 104 0.044
myeloid leukocyte differentiation GO:0002573 119 0.044
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.043
ribonucleoside triphosphate metabolic process GO:0009199 220 0.043
regulation of protein maturation GO:1903317 96 0.043
regulation of organ formation GO:0003156 34 0.043
forebrain generation of neurons GO:0021872 63 0.043
negative regulation of synapse assembly GO:0051964 3 0.043
epidermis morphogenesis GO:0048730 33 0.043
wound healing GO:0042060 157 0.043
negative regulation of neuron projection development GO:0010977 50 0.043
glycosyl compound catabolic process GO:1901658 206 0.043
negative regulation of protein processing GO:0010955 79 0.043
regulation of nucleotide catabolic process GO:0030811 122 0.043
cell maturation GO:0048469 127 0.043
Mouse
protein maturation GO:0051604 176 0.043
fibroblast growth factor production GO:0090269 4 0.043
neural crest cell development GO:0014032 48 0.043
myotube cell development GO:0014904 60 0.043
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.042
regulation of map kinase activity GO:0043405 120 0.042
response to radiation GO:0009314 165 0.042
locomotory behavior GO:0007626 195 0.042
regulation of cellular response to growth factor stimulus GO:0090287 82 0.042
trophectodermal cell differentiation GO:0001829 21 0.042
regulation of leukocyte differentiation GO:1902105 159 0.041
visual perception GO:0007601 52 0.041
negative regulation of fat cell differentiation GO:0045599 36 0.041
regulation of blood circulation GO:1903522 93 0.041
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.041
Mouse
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.041
heart growth GO:0060419 45 0.041
palate development GO:0060021 76 0.041
ribonucleoside catabolic process GO:0042454 206 0.040
positive regulation of cell projection organization GO:0031346 95 0.040
nucleoside triphosphate metabolic process GO:0009141 230 0.040
single organism cell adhesion GO:0098602 156 0.040
blastocyst formation GO:0001825 33 0.040
type b pancreatic cell proliferation GO:0044342 10 0.040
regulation of axon diameter GO:0031133 6 0.040
muscle fiber development GO:0048747 76 0.040
Mouse
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.040
regulation of peptidase activity GO:0052547 96 0.040
plasma membrane organization GO:0007009 90 0.040
nucleoside triphosphate catabolic process GO:0009143 205 0.040
mesoderm development GO:0007498 100 0.040
Mouse
nerve development GO:0021675 67 0.039
heart valve development GO:0003170 23 0.039
regulation of myeloid cell differentiation GO:0045637 96 0.039
cardiac right atrium morphogenesis GO:0003213 3 0.039
pancreatic pp cell fate commitment GO:0003329 2 0.039
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.039
auditory receptor cell fate determination GO:0042668 3 0.039
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.039
positive regulation of epidermis development GO:0045684 13 0.039
cardiac right ventricle formation GO:0003219 3 0.039
actin filament organization GO:0007015 113 0.038
multicellular organismal water homeostasis GO:0050891 23 0.038
purine containing compound metabolic process GO:0072521 311 0.038
transforming growth factor beta2 production GO:0032906 2 0.038
cell fate determination GO:0001709 32 0.038
cop9 signalosome assembly GO:0010387 2 0.038
intermediate filament cytoskeleton organization GO:0045104 26 0.038
positive regulation of growth GO:0045927 104 0.038
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.037
negative regulation of neuron apoptotic process GO:0043524 92 0.037
negative regulation of response to wounding GO:1903035 77 0.037
multicellular organismal signaling GO:0035637 91 0.037
positive regulation of cellular catabolic process GO:0031331 148 0.037
peptidyl tyrosine phosphorylation GO:0018108 143 0.037
detection of external stimulus GO:0009581 61 0.037
neural crest cell migration GO:0001755 32 0.037
visceral motor neuron differentiation GO:0021524 3 0.037
regulation of cysteine type endopeptidase activity GO:2000116 65 0.037

Irx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org