Mus musculus

55 known processes

Irx1

Iroquois related homeobox 1 (Drosophila)

Irx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.838
tendon formation GO:0035992 4 0.736
Mouse
retinal bipolar neuron differentiation GO:0060040 5 0.717
Mouse
specification of loop of henle identity GO:0072086 4 0.670
proximal distal pattern formation involved in nephron development GO:0072047 5 0.641
renal system development GO:0072001 225 0.631
pattern specification involved in metanephros development GO:0072268 4 0.601
developmental maturation GO:0021700 193 0.579
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.571
Mouse
neuron projection guidance GO:0097485 141 0.556
axonogenesis GO:0007409 274 0.539
renal tubule development GO:0061326 87 0.537
tendon cell differentiation GO:0035990 4 0.532
Mouse
segmentation GO:0035282 93 0.514
epithelial tube morphogenesis GO:0060562 303 0.504
connective tissue development GO:0061448 179 0.487
Mouse
proximal distal pattern formation involved in metanephric nephron development GO:0072272 2 0.485
tendon sheath development GO:0002932 1 0.474
Mouse
positive regulation of cell development GO:0010720 237 0.460
Mouse
forebrain development GO:0030900 302 0.458
chemotaxis GO:0006935 247 0.454
camera type eye development GO:0043010 266 0.452
Zebrafish Mouse
cell fate commitment GO:0045165 210 0.449
metanephric nephron development GO:0072210 34 0.437
stem cell development GO:0048864 219 0.435
epithelial tube formation GO:0072175 130 0.407
nephron development GO:0072006 109 0.405
nephron epithelium morphogenesis GO:0072088 68 0.403
nephron epithelium development GO:0072009 92 0.394
nephron tubule development GO:0072080 84 0.391
neural tube development GO:0021915 160 0.373
spinal cord development GO:0021510 81 0.372
paraxial mesodermal cell fate commitment GO:0048343 2 0.343
cellular response to growth factor stimulus GO:0071363 197 0.338
smoothened signaling pathway GO:0007224 105 0.337
urogenital system development GO:0001655 261 0.336
loop of henle development GO:0072070 10 0.336
kidney epithelium development GO:0072073 121 0.325
stem cell maintenance GO:0019827 130 0.321
skeletal system development GO:0001501 356 0.320
cardiac chamber morphogenesis GO:0003206 93 0.318
kidney development GO:0001822 213 0.318
gland development GO:0048732 330 0.316
morphogenesis of embryonic epithelium GO:0016331 159 0.313
regulation of myoblast differentiation GO:0045661 29 0.304
Mouse
positive regulation of nervous system development GO:0051962 221 0.302
Mouse
axon guidance GO:0007411 141 0.296
regulation of neuron differentiation GO:0045664 281 0.284
Mouse
regulation of organ morphogenesis GO:2000027 144 0.281
nephron morphogenesis GO:0072028 69 0.281
paraxial mesodermal cell differentiation GO:0048342 2 0.275
cardiac chamber development GO:0003205 108 0.275
striated muscle tissue development GO:0014706 293 0.270
Mouse
kidney morphogenesis GO:0060993 83 0.266
embryonic organ morphogenesis GO:0048562 276 0.259
Zebrafish
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.257
embryonic epithelial tube formation GO:0001838 130 0.256
muscle cell differentiation GO:0042692 261 0.252
Mouse
cerebral cortex development GO:0021987 86 0.248
limb morphogenesis GO:0035108 149 0.234
embryonic placenta development GO:0001892 98 0.233
negative regulation of myoblast differentiation GO:0045662 18 0.232
Mouse
diencephalon development GO:0021536 63 0.231
regulation of cellular amine metabolic process GO:0033238 20 0.231
skeletal system morphogenesis GO:0048705 203 0.230
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.227
ribonucleotide catabolic process GO:0009261 208 0.227
nephron tubule morphogenesis GO:0072078 68 0.226
stem cell differentiation GO:0048863 268 0.225
cellular ketone metabolic process GO:0042180 84 0.219
collagen fibril organization GO:0030199 32 0.217
Mouse
central nervous system neuron differentiation GO:0021953 162 0.215
Zebrafish
telencephalon development GO:0021537 186 0.214
regulation of cell projection organization GO:0031344 206 0.214
cellular amine metabolic process GO:0044106 44 0.213
pallium development GO:0021543 120 0.210
bmp signaling pathway GO:0030509 93 0.208
negative regulation of cell development GO:0010721 169 0.204
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.200
branching morphogenesis of an epithelial tube GO:0048754 159 0.200
regulation of skeletal muscle fiber development GO:0048742 36 0.199
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.196
regulation of auditory receptor cell differentiation GO:0045607 4 0.193
embryonic skeletal system morphogenesis GO:0048704 91 0.192
regulation of myotube differentiation GO:0010830 62 0.192
Mouse
cellular amino acid metabolic process GO:0006520 103 0.191
erythrocyte differentiation GO:0030218 88 0.189
specification of nephron tubule identity GO:0072081 5 0.182
neural tube formation GO:0001841 108 0.182
sensory organ morphogenesis GO:0090596 242 0.181
Zebrafish Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.178
establishment of organ orientation GO:0048561 1 0.177
developmental growth involved in morphogenesis GO:0060560 138 0.171
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.170
amine metabolic process GO:0009308 45 0.169
regulation of bmp signaling pathway GO:0030510 60 0.169
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.168
epidermis development GO:0008544 187 0.167
regulation of cell motility GO:2000145 236 0.164
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.164
ear morphogenesis GO:0042471 118 0.163
Zebrafish
muscle tissue development GO:0060537 308 0.163
Mouse
retina development in camera type eye GO:0060041 119 0.161
Zebrafish Mouse
ossification GO:0001503 216 0.161
extracellular structure organization GO:0043062 148 0.160
Mouse
purine containing compound metabolic process GO:0072521 311 0.160
mesenchymal cell development GO:0014031 93 0.157
collagen biosynthetic process GO:0032964 7 0.153
Mouse
embryonic skeletal system development GO:0048706 120 0.153
negative regulation of nervous system development GO:0051961 156 0.151
Mouse
myotube differentiation GO:0014902 105 0.148
Mouse
mesoderm development GO:0007498 100 0.148
Mouse
tube formation GO:0035148 140 0.147
brain segmentation GO:0035284 3 0.147
morphogenesis of a polarized epithelium GO:0001738 37 0.147
negative regulation of molecular function GO:0044092 258 0.147
midbrain hindbrain boundary maturation GO:0021732 1 0.146
pyramidal neuron migration GO:0021852 1 0.145
mesenchyme development GO:0060485 152 0.143
skeletal muscle fiber development GO:0048741 58 0.142
Mouse
hindbrain formation GO:0021576 1 0.141
cell adhesion GO:0007155 329 0.140
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.140
retina morphogenesis in camera type eye GO:0060042 45 0.138
Zebrafish Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.138
negative regulation of muscle cell differentiation GO:0051148 33 0.137
Mouse
blood vessel morphogenesis GO:0048514 285 0.137
regulation of neuron apoptotic process GO:0043523 122 0.137
epithelial to mesenchymal transition GO:0001837 47 0.136
central nervous system morphogenesis GO:0021551 2 0.136
myotube cell development GO:0014904 60 0.135
Mouse
circulatory system process GO:0003013 197 0.133
Mouse
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.133
regulation of epithelial cell migration GO:0010632 35 0.132
extracellular matrix organization GO:0030198 147 0.131
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.130
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.129
regulation of rho gtpase activity GO:0032319 58 0.129
positive regulation of stem cell proliferation GO:2000648 59 0.126
mesenchymal cell differentiation GO:0048762 107 0.126
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.125
ribonucleoside catabolic process GO:0042454 206 0.125
negative regulation of cell proliferation GO:0008285 296 0.125
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.124
skin development GO:0043588 220 0.124
response to growth factor GO:0070848 198 0.124
dendrite development GO:0016358 115 0.122
regulation of system process GO:0044057 200 0.122
Mouse
muscle fiber development GO:0048747 76 0.120
Mouse
heart morphogenesis GO:0003007 178 0.120
cell maturation GO:0048469 127 0.119
Mouse
cardiac ventricle development GO:0003231 83 0.118
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.115
renal vesicle induction GO:0072034 3 0.114
cellular nitrogen compound catabolic process GO:0044270 280 0.113
digestive system development GO:0055123 200 0.111
regulation of multicellular organismal metabolic process GO:0044246 14 0.111
Mouse
gliogenesis GO:0042063 141 0.110
negative regulation of neuron differentiation GO:0045665 101 0.109
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.109
regulation of axon extension GO:0030516 43 0.108
stem cell proliferation GO:0072089 117 0.107
myoblast differentiation GO:0045445 52 0.106
Mouse
motor neuron migration GO:0097475 4 0.106
mammary gland duct morphogenesis GO:0060603 38 0.105
neuron migration GO:0001764 122 0.104
neural tube closure GO:0001843 90 0.104
astrocyte fate commitment GO:0060018 4 0.103
neural retina development GO:0003407 41 0.102
Mouse
skeletal muscle organ development GO:0060538 163 0.102
Mouse
regulation of cell migration GO:0030334 219 0.102
placenta development GO:0001890 140 0.102
olfactory bulb interneuron differentiation GO:0021889 12 0.101
neural crest cell differentiation GO:0014033 54 0.101
trachea cartilage morphogenesis GO:0060535 4 0.101
epithelial cell development GO:0002064 159 0.100
lung development GO:0030324 164 0.099
fat cell differentiation GO:0045444 160 0.099
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.099
metanephric loop of henle development GO:0072236 4 0.097
response to transforming growth factor beta GO:0071559 88 0.097
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.097
renal outer medulla development GO:0072054 2 0.097
metanephros development GO:0001656 79 0.096
skeletal muscle cell differentiation GO:0035914 66 0.096
ear development GO:0043583 200 0.096
Zebrafish
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.096
oviduct development GO:0060066 3 0.095
mammary gland epithelial cell proliferation GO:0033598 24 0.095
morphogenesis of a branching structure GO:0001763 203 0.094
organonitrogen compound catabolic process GO:1901565 264 0.094
morphogenesis of a branching epithelium GO:0061138 193 0.094
regulation of neuron death GO:1901214 134 0.093
ribonucleoside triphosphate catabolic process GO:0009203 199 0.093
cell fate determination GO:0001709 32 0.093
cartilage development GO:0051216 140 0.092
forebrain regionalization GO:0021871 25 0.092
tube closure GO:0060606 91 0.091
cerebellum formation GO:0021588 1 0.091
respiratory system development GO:0060541 190 0.090
organophosphate catabolic process GO:0046434 232 0.090
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.090
forebrain generation of neurons GO:0021872 63 0.090
ras protein signal transduction GO:0007265 77 0.089
cell differentiation in spinal cord GO:0021515 53 0.089
renal tubule morphogenesis GO:0061333 72 0.087
nucleoside phosphate metabolic process GO:0006753 338 0.087
nucleotide metabolic process GO:0009117 332 0.087
prostate gland stromal morphogenesis GO:0060741 2 0.086
negative regulation of synapse maturation GO:2000297 2 0.085
mesonephric duct formation GO:0072181 2 0.085
digestive tract morphogenesis GO:0048546 147 0.084
protein ubiquitination GO:0016567 171 0.084
lateral line system development GO:0048925 1 0.083
positive regulation of anagen GO:0051885 1 0.082
nucleoside catabolic process GO:0009164 206 0.082
spinal cord association neuron differentiation GO:0021527 14 0.082
outflow tract morphogenesis GO:0003151 53 0.081
primary neural tube formation GO:0014020 95 0.081
somitogenesis GO:0001756 69 0.081
negative regulation of cellular amine metabolic process GO:0033239 1 0.081
glucose homeostasis GO:0042593 128 0.081
multicellular organismal metabolic process GO:0044236 28 0.080
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.080
mammary gland epithelium development GO:0061180 65 0.080
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.080
mesoderm formation GO:0001707 62 0.080
nucleotide catabolic process GO:0009166 217 0.080
t cell differentiation GO:0030217 174 0.080
segment specification GO:0007379 15 0.080
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.079
negative regulation of growth GO:0045926 99 0.079
somatic stem cell maintenance GO:0035019 47 0.079
organic cyclic compound catabolic process GO:1901361 295 0.079
gas homeostasis GO:0033483 3 0.078
guanosine containing compound metabolic process GO:1901068 144 0.078
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.078
sensory neuron axon guidance GO:0097374 3 0.077
purine nucleoside catabolic process GO:0006152 205 0.077
hindbrain development GO:0030902 128 0.076
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.076
trophectodermal cell differentiation GO:0001829 21 0.076
spinal cord motor neuron migration GO:0097476 4 0.076
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.076
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.075
axis elongation involved in somitogenesis GO:0090245 4 0.075
nephron tubule formation GO:0072079 20 0.075
endocrine system development GO:0035270 98 0.075
purine nucleotide catabolic process GO:0006195 211 0.075
renal system pattern specification GO:0072048 9 0.074
regulation of neuron projection development GO:0010975 169 0.074
epithelium migration GO:0090132 63 0.074
auditory receptor cell fate determination GO:0042668 3 0.073
hemangioblast cell differentiation GO:0060217 1 0.073
aromatic compound catabolic process GO:0019439 286 0.072
hair follicle development GO:0001942 85 0.072
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.072
synaptic transmission GO:0007268 329 0.072
Worm
auditory receptor cell fate specification GO:0042667 1 0.072
outer medullary collecting duct development GO:0072060 1 0.072
notch signaling pathway GO:0007219 71 0.071
regulation of retina development in camera type eye GO:1902866 3 0.071
artery development GO:0060840 53 0.071
regulation of mitotic cell cycle GO:0007346 126 0.070
purine containing compound catabolic process GO:0072523 213 0.070
regulation of hydrolase activity GO:0051336 246 0.070
central nervous system vasculogenesis GO:0022009 3 0.070
purine nucleoside triphosphate catabolic process GO:0009146 203 0.070
sensory system development GO:0048880 3 0.070
blastocyst formation GO:0001825 33 0.069
metencephalon development GO:0022037 89 0.069
epithelial cell proliferation GO:0050673 174 0.069
cell type specific apoptotic process GO:0097285 268 0.069
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.069
positive regulation of cell motility GO:2000147 116 0.068
lung induction GO:0060492 3 0.068
gonad development GO:0008406 141 0.068
transdifferentiation GO:0060290 1 0.068
leukocyte differentiation GO:0002521 342 0.068
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.067
regulation of cellular catabolic process GO:0031329 242 0.067
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.067
positive regulation of protein modification process GO:0031401 299 0.067
purine nucleoside metabolic process GO:0042278 241 0.066
dopaminergic neuron differentiation GO:0071542 14 0.066
negative regulation of neuron death GO:1901215 98 0.066
regulation of mast cell differentiation GO:0060375 3 0.066
gtp metabolic process GO:0046039 144 0.065
nucleoside triphosphate metabolic process GO:0009141 230 0.065
positive regulation of cell cycle GO:0045787 92 0.065
protein modification by small protein conjugation or removal GO:0070647 207 0.065
regulation of organelle organization GO:0033043 289 0.065
blood circulation GO:0008015 195 0.065
Mouse
ameboidal type cell migration GO:0001667 128 0.064
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.064
ureteric bud morphogenesis GO:0060675 62 0.064
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.064
lymphocyte differentiation GO:0030098 242 0.064
purine ribonucleotide metabolic process GO:0009150 290 0.064
cellular chemical homeostasis GO:0055082 215 0.062
cellular response to external stimulus GO:0071496 88 0.062
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.062
actin filament organization GO:0007015 113 0.062
motor neuron axon guidance GO:0008045 26 0.062
hypophysis morphogenesis GO:0048850 3 0.062
olfactory bulb development GO:0021772 30 0.061
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.061
determination of left right symmetry GO:0007368 80 0.061
myeloid cell homeostasis GO:0002262 114 0.061
neuron fate specification GO:0048665 30 0.061
rho protein signal transduction GO:0007266 32 0.061
male sex differentiation GO:0046661 109 0.061
regulation of ras protein signal transduction GO:0046578 114 0.061
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.061
corpus callosum morphogenesis GO:0021540 3 0.061
cardiac muscle tissue morphogenesis GO:0055008 44 0.060
mesangial cell differentiation GO:0072007 4 0.060
uterus morphogenesis GO:0061038 2 0.060
gtp catabolic process GO:0006184 143 0.060
mechanoreceptor differentiation GO:0042490 67 0.060
inner ear morphogenesis GO:0042472 101 0.059
Zebrafish
gastrulation GO:0007369 116 0.059
ribonucleotide metabolic process GO:0009259 291 0.059
muscle cell development GO:0055001 133 0.058
Mouse
oxygen homeostasis GO:0032364 2 0.058
regulation of anagen GO:0051884 1 0.058
purine ribonucleoside catabolic process GO:0046130 205 0.058
regulation of cellular response to growth factor stimulus GO:0090287 82 0.058
cell growth GO:0016049 130 0.058
androgen biosynthetic process GO:0006702 4 0.058
respiratory tube development GO:0030323 167 0.058
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.058
regulation of nucleoside metabolic process GO:0009118 130 0.058
purine nucleotide metabolic process GO:0006163 302 0.058
polarity specification of proximal distal axis GO:0010085 2 0.057
bone morphogenesis GO:0060349 78 0.057
mesonephric duct morphogenesis GO:0072180 4 0.057
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.057
neuron projection extension GO:1990138 64 0.057
cardiac right atrium morphogenesis GO:0003213 3 0.057
nucleoside triphosphate catabolic process GO:0009143 205 0.057
regulation of neural retina development GO:0061074 3 0.056
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.056
striated muscle cell development GO:0055002 125 0.056
Mouse
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.056
regulation of cellular response to stress GO:0080135 159 0.055
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.055
hippocampus development GO:0021766 52 0.055
regulation of smoothened signaling pathway GO:0008589 58 0.055
hindbrain morphogenesis GO:0021575 46 0.055
body morphogenesis GO:0010171 45 0.055
Worm
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.054
angiogenesis GO:0001525 201 0.054
regulation of nucleotide catabolic process GO:0030811 122 0.054
small gtpase mediated signal transduction GO:0007264 97 0.054
transmission of nerve impulse GO:0019226 76 0.054
epithelial cell migration GO:0010631 63 0.054
forebrain neuron differentiation GO:0021879 52 0.054
central nervous system neuron development GO:0021954 67 0.054
neuron apoptotic process GO:0051402 142 0.054
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.054
synapse organization GO:0050808 125 0.054
appendage morphogenesis GO:0035107 149 0.054
Zebrafish
pattern specification involved in kidney development GO:0061004 8 0.054
regulation of striated muscle cell differentiation GO:0051153 81 0.053
Mouse
interleukin 8 production GO:0032637 4 0.053
regulation of protein localization GO:0032880 231 0.053
hair follicle morphogenesis GO:0031069 29 0.053
canonical wnt signaling pathway GO:0060070 130 0.053
hair cycle GO:0042633 90 0.052
regulation of homeostatic process GO:0032844 182 0.052
purine nucleoside triphosphate metabolic process GO:0009144 226 0.052
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.052
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.052
neuroblast proliferation GO:0007405 49 0.052
regulation of secretion by cell GO:1903530 249 0.052
positive regulation of cell migration GO:0030335 109 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
regulation of ras gtpase activity GO:0032318 88 0.052
heterocycle catabolic process GO:0046700 280 0.051
central nervous system segmentation GO:0035283 3 0.051
anterior commissure morphogenesis GO:0021960 6 0.051
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.051
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.051
peripheral nervous system development GO:0007422 53 0.051
cellular response to monosaccharide stimulus GO:0071326 47 0.051
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.050
establishment of anatomical structure orientation GO:0048560 1 0.050
bone development GO:0060348 120 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.050
regulation of epithelial cell proliferation GO:0050678 141 0.050
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.050
mesonephric tubule development GO:0072164 94 0.050
compound eye development GO:0048749 1 0.049
regulation of body fluid levels GO:0050878 162 0.049
regulation of hormone levels GO:0010817 211 0.049
positive regulation of neuron projection development GO:0010976 79 0.049
pancreatic pp cell differentiation GO:0003312 2 0.049
regulation of transferase activity GO:0051338 263 0.049
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.049
determination of heart left right asymmetry GO:0061371 48 0.049
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.049
limb development GO:0060173 166 0.048
paraxial mesoderm development GO:0048339 18 0.048
ribose phosphate metabolic process GO:0019693 291 0.048
spemann organizer formation GO:0060061 2 0.048
glomerular mesangial cell development GO:0072144 3 0.048
regulation of purine nucleotide metabolic process GO:1900542 169 0.048
negative regulation of protein metabolic process GO:0051248 282 0.048
carbohydrate homeostasis GO:0033500 128 0.048
regulation of myeloid cell differentiation GO:0045637 96 0.048
chromatin modification GO:0016568 187 0.048
renal capsule specification GO:0072130 1 0.048
myeloid cell differentiation GO:0030099 233 0.048
regulation of cell size GO:0008361 72 0.048
positive regulation of organelle organization GO:0010638 128 0.048
cardiac epithelial to mesenchymal transition GO:0060317 18 0.047
regulation of endothelial cell migration GO:0010594 22 0.047
development of primary sexual characteristics GO:0045137 143 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.047
neural precursor cell proliferation GO:0061351 121 0.047
mesoderm morphogenesis GO:0048332 64 0.047
positive regulation of cell adhesion GO:0045785 80 0.046
regulation of cellular component biogenesis GO:0044087 181 0.046
neuron death GO:0070997 154 0.046
pancreatic a cell fate commitment GO:0003326 2 0.046
positive regulation of epithelial cell proliferation GO:0050679 68 0.046
regulation of purine nucleotide catabolic process GO:0033121 122 0.046
locomotory behavior GO:0007626 195 0.046
chromatin organization GO:0006325 206 0.046
organ growth GO:0035265 117 0.046
potassium ion homeostasis GO:0055075 4 0.046
glomerular mesangial cell differentiation GO:0072008 3 0.046
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.046
aortic valve morphogenesis GO:0003180 4 0.046
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.046
developmental induction GO:0031128 34 0.045
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.045
cerebral cortex radial glia guided migration GO:0021801 17 0.045
olfactory lobe development GO:0021988 32 0.045
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.045
glycosyl compound metabolic process GO:1901657 246 0.045
establishment or maintenance of cell polarity GO:0007163 86 0.045
mesenchyme morphogenesis GO:0072132 32 0.045
neural crest cell development GO:0014032 48 0.045
inner medullary collecting duct development GO:0072061 2 0.045
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.045
regulation of vascular wound healing GO:0061043 2 0.045
establishment of endothelial blood brain barrier GO:0014045 3 0.045
mitral valve development GO:0003174 4 0.045
multicellular organismal macromolecule metabolic process GO:0044259 19 0.044
Mouse
embryonic limb morphogenesis GO:0030326 126 0.044
cardiac right ventricle formation GO:0003219 3 0.044
developmental cell growth GO:0048588 84 0.044
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.044
ribonucleoside triphosphate metabolic process GO:0009199 220 0.044
regulation of kidney development GO:0090183 40 0.044
renal inner medulla development GO:0072053 3 0.044
protein modification by small protein conjugation GO:0032446 187 0.044
regulation of ossification GO:0030278 112 0.044
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.044
epithelial cell morphogenesis GO:0003382 41 0.044
homeostasis of number of cells GO:0048872 210 0.044
pancreatic pp cell fate commitment GO:0003329 2 0.044
branching involved in ureteric bud morphogenesis GO:0001658 56 0.043
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.043
embryonic heart tube morphogenesis GO:0003143 51 0.043
ectoderm formation GO:0001705 3 0.043
skin morphogenesis GO:0043589 38 0.043
positive regulation of neural precursor cell proliferation GO:2000179 42 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
positive regulation of interleukin 8 secretion GO:2000484 1 0.043
purine ribonucleotide catabolic process GO:0009154 208 0.043
glycosyl compound catabolic process GO:1901658 206 0.042
sensory perception GO:0007600 245 0.042
multicellular organismal signaling GO:0035637 91 0.042
epidermis morphogenesis GO:0048730 33 0.042
positive regulation of cellular catabolic process GO:0031331 148 0.042
hair cell differentiation GO:0035315 40 0.042
multicellular organismal homeostasis GO:0048871 164 0.042
renal capsule morphogenesis GO:0072128 1 0.042
positive regulation of bmp signaling pathway GO:0030513 23 0.042
regulation of stem cell proliferation GO:0072091 78 0.042
stress activated mapk cascade GO:0051403 80 0.041
regulation of organ formation GO:0003156 34 0.041
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.041
multi multicellular organism process GO:0044706 109 0.041
actin cytoskeleton organization GO:0030036 220 0.041
auditory receptor cell differentiation GO:0042491 37 0.041
regulation of mesenchymal cell proliferation GO:0010464 37 0.041
autonomic nervous system development GO:0048483 43 0.041
glomerulus development GO:0032835 40 0.041
carbon catabolite activation of transcription GO:0045991 4 0.041
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.041
hematopoietic progenitor cell differentiation GO:0002244 143 0.041
regulation of epithelial to mesenchymal transition GO:0010717 22 0.040

Irx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org