Mus musculus

18 known processes

Plch2

phospholipase C, eta 2

(Aliases: Plcl4,PLCeta2,Plc-eta2,A930027K05Rik)

Plch2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.287
regulation of cell projection organization GO:0031344 206 0.073
blood circulation GO:0008015 195 0.070
cation homeostasis GO:0055080 212 0.068
Mouse
cation transmembrane transport GO:0098655 266 0.062
Mouse
regulation of kinase activity GO:0043549 249 0.061
regulation of hydrolase activity GO:0051336 246 0.059
small gtpase mediated signal transduction GO:0007264 97 0.059
aromatic compound catabolic process GO:0019439 286 0.057
regulation of cellular catabolic process GO:0031329 242 0.054
ras protein signal transduction GO:0007265 77 0.051
cellular nitrogen compound catabolic process GO:0044270 280 0.050
purine nucleoside metabolic process GO:0042278 241 0.050
regulation of transferase activity GO:0051338 263 0.049
regulation of membrane potential GO:0042391 192 0.049
regulation of cellular response to stress GO:0080135 159 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
single fertilization GO:0007338 82 0.048
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.048
cation transport GO:0006812 399 0.046
Mouse
cell adhesion GO:0007155 329 0.045
regulation of secretion GO:0051046 274 0.045
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.044
transmembrane transport GO:0055085 412 0.043
Mouse
purine containing compound metabolic process GO:0072521 311 0.043
cellular ketone metabolic process GO:0042180 84 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.042
purine nucleoside triphosphate metabolic process GO:0009144 226 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.042
organic cyclic compound catabolic process GO:1901361 295 0.041
regulation of mapk cascade GO:0043408 248 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
organophosphate catabolic process GO:0046434 232 0.040
cellular amino acid metabolic process GO:0006520 103 0.040
axonogenesis GO:0007409 274 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
retina development in camera type eye GO:0060041 119 0.040
cell type specific apoptotic process GO:0097285 268 0.040
ribonucleoside catabolic process GO:0042454 206 0.039
mapk cascade GO:0000165 281 0.039
purine ribonucleoside catabolic process GO:0046130 205 0.039
rho protein signal transduction GO:0007266 32 0.038
fertilization GO:0009566 127 0.038
Mouse
nucleotide metabolic process GO:0009117 332 0.038
inorganic ion transmembrane transport GO:0098660 234 0.038
Mouse
regulation of neuron differentiation GO:0045664 281 0.038
ion transmembrane transport GO:0034220 361 0.038
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.038
response to organonitrogen compound GO:0010243 246 0.037
nucleoside metabolic process GO:0009116 246 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
synapse organization GO:0050808 125 0.036
nucleoside phosphate catabolic process GO:1901292 222 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
sensory perception GO:0007600 245 0.036
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.036
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
nucleoside catabolic process GO:0009164 206 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
regulation of neuron projection development GO:0010975 169 0.035
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
positive regulation of mapk cascade GO:0043410 170 0.034
heterocycle catabolic process GO:0046700 280 0.034
amine metabolic process GO:0009308 45 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
plasma membrane organization GO:0007009 90 0.033
phospholipid metabolic process GO:0006644 87 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
action potential GO:0001508 78 0.031
regulation of purine nucleotide catabolic process GO:0033121 122 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
regulation of lipid metabolic process GO:0019216 118 0.029
muscle contraction GO:0006936 101 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
negative regulation of cell proliferation GO:0008285 296 0.028
nucleotide catabolic process GO:0009166 217 0.028
gland development GO:0048732 330 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.028
skin development GO:0043588 220 0.027
regulation of anatomical structure size GO:0090066 178 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
exocytosis GO:0006887 121 0.026
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
positive regulation of kinase activity GO:0033674 155 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
cellular amine metabolic process GO:0044106 44 0.025
metal ion homeostasis GO:0055065 189 0.025
Mouse
negative regulation of cell development GO:0010721 169 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
synaptic transmission GO:0007268 329 0.025
Mouse
regulation of ion transport GO:0043269 215 0.025
Mouse
muscle system process GO:0003012 141 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.024
sensory perception of light stimulus GO:0050953 54 0.024
peptidyl amino acid modification GO:0018193 336 0.024
Mouse
calcium ion homeostasis GO:0055074 127 0.024
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
forebrain development GO:0030900 302 0.024
Mouse
locomotory behavior GO:0007626 195 0.023
membrane organization GO:0061024 245 0.023
regulation of cell adhesion GO:0030155 154 0.023
positive regulation of transferase activity GO:0051347 167 0.022
positive regulation of gtpase activity GO:0043547 85 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
gtp catabolic process GO:0006184 143 0.022
purine containing compound catabolic process GO:0072523 213 0.022
anion transport GO:0006820 177 0.022
circulatory system process GO:0003013 197 0.022
regulation of gtp catabolic process GO:0033124 113 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
divalent inorganic cation transport GO:0072511 178 0.021
Mouse
inter male aggressive behavior GO:0002121 3 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
negative regulation of molecular function GO:0044092 258 0.021
muscle cell differentiation GO:0042692 261 0.021
Mouse
positive regulation of protein modification process GO:0031401 299 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
regulation of cell migration GO:0030334 219 0.020
Mouse
telencephalon development GO:0021537 186 0.020
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
endomembrane system organization GO:0010256 147 0.020
cellular homeostasis GO:0019725 240 0.020
Mouse
regulation of blood pressure GO:0008217 93 0.020
heart process GO:0003015 94 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
myeloid cell differentiation GO:0030099 233 0.020
ameboidal type cell migration GO:0001667 128 0.019
establishment of organelle localization GO:0051656 122 0.019
regulation of proteolysis GO:0030162 164 0.019
gtp metabolic process GO:0046039 144 0.019
regulation of protein kinase activity GO:0045859 232 0.019
organic anion transport GO:0015711 137 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
response to organic cyclic compound GO:0014070 198 0.019
heart contraction GO:0060047 93 0.019
rap protein signal transduction GO:0032486 3 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
positive regulation of cell migration GO:0030335 109 0.018
protein localization to organelle GO:0033365 185 0.018
carboxylic acid transport GO:0046942 100 0.018
organelle localization GO:0051640 179 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
regulation of metal ion transport GO:0010959 106 0.018
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.018
Mouse
epithelial cell proliferation GO:0050673 174 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
macromolecule catabolic process GO:0009057 281 0.017
carbohydrate metabolic process GO:0005975 230 0.017
regulation of system process GO:0044057 200 0.017
urogenital system development GO:0001655 261 0.017
camera type eye development GO:0043010 266 0.017
wound healing GO:0042060 157 0.017
microtubule based process GO:0007017 236 0.017
multicellular organismal signaling GO:0035637 91 0.017
regulation of transmembrane transport GO:0034762 128 0.017
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
regulation of map kinase activity GO:0043405 120 0.016
leukocyte differentiation GO:0002521 342 0.016
Mouse
negative regulation of cell projection organization GO:0031345 56 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
oxidation reduction process GO:0055114 342 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
Mouse
negative regulation of cell adhesion GO:0007162 45 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
sodium ion transport GO:0006814 73 0.016
dendrite development GO:0016358 115 0.016
regulation of organelle organization GO:0033043 289 0.015
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
mitotic cell cycle process GO:1903047 159 0.015
Mouse
cellular chemical homeostasis GO:0055082 215 0.015
Mouse
response to radiation GO:0009314 165 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
potassium ion homeostasis GO:0055075 4 0.015
negative regulation of neuron projection development GO:0010977 50 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
regulation of hormone levels GO:0010817 211 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
Mouse
calcium ion transport GO:0006816 159 0.015
Mouse
stress activated mapk cascade GO:0051403 80 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
multicellular organismal homeostasis GO:0048871 164 0.014
pallium development GO:0021543 120 0.014
Mouse
lateral inhibition GO:0046331 1 0.014
regulation of cell motility GO:2000145 236 0.014
Mouse
nitrogen compound transport GO:0071705 271 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
Mouse
neuron death GO:0070997 154 0.014
regulation of systemic arterial blood pressure GO:0003073 61 0.014
neuron apoptotic process GO:0051402 142 0.014
lipid biosynthetic process GO:0008610 179 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
regulation of neuron death GO:1901214 134 0.013
positive regulation of cell motility GO:2000147 116 0.013
positive regulation of nervous system development GO:0051962 221 0.013
stem cell differentiation GO:0048863 268 0.013
epidermis development GO:0008544 187 0.013
peptide secretion GO:0002790 114 0.013
epithelial cell development GO:0002064 159 0.013
homeostasis of number of cells GO:0048872 210 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
cell substrate adhesion GO:0031589 130 0.013
regulation of feeding behavior GO:0060259 3 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
male gamete generation GO:0048232 285 0.012
protein targeting GO:0006605 143 0.012
regulation of response to wounding GO:1903034 189 0.012
maintenance of location GO:0051235 89 0.012
Mouse
regulation of homeostatic process GO:0032844 182 0.012
Mouse
conditioned taste aversion GO:0001661 4 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
Mouse
axon guidance GO:0007411 141 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
single organism cell adhesion GO:0098602 156 0.012
regulation of protein transport GO:0051223 163 0.012
protein maturation GO:0051604 176 0.012
response to light stimulus GO:0009416 135 0.012
glycoprotein metabolic process GO:0009100 116 0.012
Mouse
positive regulation of cell development GO:0010720 237 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
Mouse
positive regulation of cell projection organization GO:0031346 95 0.012
regulation of secretion by cell GO:1903530 249 0.012
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.012
striated muscle tissue development GO:0014706 293 0.012
Mouse
neuronal action potential GO:0019228 54 0.011
regulation of protein localization GO:0032880 231 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
cell chemotaxis GO:0060326 81 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
striated muscle contraction GO:0006941 45 0.011
leukocyte proliferation GO:0070661 172 0.011
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
negative regulation of organelle organization GO:0010639 90 0.011
sperm motility GO:0030317 47 0.011
negative regulation of neuron death GO:1901215 98 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
lipid localization GO:0010876 126 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
protein localization to plasma membrane GO:0072659 57 0.011
tissue remodeling GO:0048771 102 0.011
anatomical structure homeostasis GO:0060249 145 0.011
activation of mapk activity GO:0000187 59 0.011
regulation of blood circulation GO:1903522 93 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
negative regulation of protein processing GO:0010955 79 0.011
muscle tissue development GO:0060537 308 0.011
Mouse
defecation GO:0030421 1 0.011
chemotaxis GO:0006935 247 0.011
peptide transport GO:0015833 133 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
rhythmic process GO:0048511 174 0.011
renal system development GO:0072001 225 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
protein localization to membrane GO:0072657 108 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
fatty acid metabolic process GO:0006631 121 0.011
multicellular organism growth GO:0035264 161 0.011
divalent metal ion transport GO:0070838 172 0.011
Mouse
phosphatidylinositol metabolic process GO:0046488 45 0.011
negative regulation of neuron projection regeneration GO:0070571 3 0.011
fasciculation of motor neuron axon GO:0097156 2 0.011
cellular response to lipid GO:0071396 145 0.011
protein catabolic process GO:0030163 221 0.010
regulation of cellular component size GO:0032535 121 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
sulfur compound metabolic process GO:0006790 100 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
Mouse
oocyte construction GO:0007308 2 0.010
ear development GO:0043583 200 0.010
regulation of jnk cascade GO:0046328 62 0.010
regulation of ras protein signal transduction GO:0046578 114 0.010
organelle assembly GO:0070925 177 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
sodium ion transmembrane transport GO:0035725 49 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.010

Plch2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
eye and adnexa disease DOID:1492 0 0.020
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.020
disease of anatomical entity DOID:7 0 0.020
retinal degeneration DOID:8466 0 0.015
eye disease DOID:5614 0 0.015
retinal disease DOID:5679 0 0.015
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of cellular proliferation DOID:14566 0 0.012