Mus musculus

12 known processes

Unc45a

unc-45 homolog A (C. elegans)

(Aliases: AW538196)

Unc45a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleotide metabolic process GO:0009259 291 0.082
regulation of cellular ketone metabolic process GO:0010565 66 0.081
purine nucleotide metabolic process GO:0006163 302 0.081
glycosyl compound metabolic process GO:1901657 246 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.068
ribonucleotide catabolic process GO:0009261 208 0.065
regulation of mapk cascade GO:0043408 248 0.064
purine containing compound catabolic process GO:0072523 213 0.059
purine nucleoside metabolic process GO:0042278 241 0.057
organic cyclic compound catabolic process GO:1901361 295 0.057
nucleoside phosphate metabolic process GO:0006753 338 0.056
nucleoside monophosphate metabolic process GO:0009123 85 0.056
ribonucleoside triphosphate metabolic process GO:0009199 220 0.056
purine nucleoside triphosphate metabolic process GO:0009144 226 0.056
nucleoside triphosphate metabolic process GO:0009141 230 0.055
nucleoside phosphate catabolic process GO:1901292 222 0.054
amine metabolic process GO:0009308 45 0.054
heterocycle catabolic process GO:0046700 280 0.052
glycosyl compound catabolic process GO:1901658 206 0.051
nucleoside metabolic process GO:0009116 246 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
purine containing compound metabolic process GO:0072521 311 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.049
cellular amine metabolic process GO:0044106 44 0.048
regulation of protein localization GO:0032880 231 0.046
nucleotide metabolic process GO:0009117 332 0.046
actin cytoskeleton organization GO:0030036 220 0.046
Fly
ribose phosphate metabolic process GO:0019693 291 0.046
nucleoside triphosphate catabolic process GO:0009143 205 0.045
ribonucleoside triphosphate catabolic process GO:0009203 199 0.045
purine ribonucleoside metabolic process GO:0046128 241 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
cellular lipid metabolic process GO:0044255 323 0.044
aromatic compound catabolic process GO:0019439 286 0.044
ras protein signal transduction GO:0007265 77 0.044
cellular ketone metabolic process GO:0042180 84 0.043
nucleoside catabolic process GO:0009164 206 0.043
cellular amino acid metabolic process GO:0006520 103 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.042
purine nucleoside catabolic process GO:0006152 205 0.041
ribonucleoside catabolic process GO:0042454 206 0.038
nucleotide catabolic process GO:0009166 217 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.037
endocytosis GO:0006897 168 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
regulation of lymphocyte activation GO:0051249 240 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
positive regulation of protein phosphorylation GO:0001934 242 0.036
asymmetric neuroblast division GO:0055059 1 0.036
macromolecule catabolic process GO:0009057 281 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
regulation of nucleotide metabolic process GO:0006140 169 0.035
cytoplasmic transport GO:0016482 234 0.035
regulation of kinase activity GO:0043549 249 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.034
regulation of cell motility GO:2000145 236 0.034
ribonucleoside monophosphate catabolic process GO:0009158 57 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
membrane organization GO:0061024 245 0.033
regulation of cell activation GO:0050865 289 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.033
ion transmembrane transport GO:0034220 361 0.032
positive regulation of cellular catabolic process GO:0031331 148 0.032
maintenance of location GO:0051235 89 0.032
regulation of transferase activity GO:0051338 263 0.032
nitrogen compound transport GO:0071705 271 0.032
leukocyte differentiation GO:0002521 342 0.032
organelle localization GO:0051640 179 0.032
cellular protein catabolic process GO:0044257 155 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
response to organonitrogen compound GO:0010243 246 0.031
cation transmembrane transport GO:0098655 266 0.031
cell type specific apoptotic process GO:0097285 268 0.031
purine nucleotide catabolic process GO:0006195 211 0.031
regulation of t cell activation GO:0050863 170 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.030
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.030
negative regulation of molecular function GO:0044092 258 0.029
lymphocyte differentiation GO:0030098 242 0.029
regulation of secretion GO:0051046 274 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
regulation of organelle organization GO:0033043 289 0.029
protein catabolic process GO:0030163 221 0.029
positive regulation of protein modification process GO:0031401 299 0.028
regulation of protein kinase activity GO:0045859 232 0.028
regulation of intracellular transport GO:0032386 159 0.028
axonogenesis GO:0007409 274 0.028
sequestering of calcium ion GO:0051208 18 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
t cell activation GO:0042110 289 0.027
apoptotic signaling pathway GO:0097190 306 0.027
purine nucleoside monophosphate metabolic process GO:0009126 81 0.026
synaptic transmission GO:0007268 329 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
establishment of organelle localization GO:0051656 122 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
asymmetric stem cell division GO:0098722 3 0.025
regulation of cellular response to stress GO:0080135 159 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.025
atp metabolic process GO:0046034 75 0.025
atp catabolic process GO:0006200 55 0.024
retrograde transport endosome to golgi GO:0042147 2 0.024
ribonucleoside monophosphate metabolic process GO:0009161 80 0.024
nucleoside monophosphate catabolic process GO:0009125 59 0.024
cation transport GO:0006812 399 0.024
regulation of defense response GO:0031347 233 0.024
Fly
purine nucleoside monophosphate catabolic process GO:0009128 58 0.024
camera type eye development GO:0043010 266 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.023
regulation of secretion by cell GO:1903530 249 0.023
regulation of hydrolase activity GO:0051336 246 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
telencephalon development GO:0021537 186 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
positive regulation of programmed cell death GO:0043068 218 0.022
germ cell development GO:0007281 185 0.022
negative regulation of immune system process GO:0002683 209 0.022
Fly
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
microtubule based process GO:0007017 236 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
regulation of cell growth GO:0001558 91 0.022
cellular response to cytokine stimulus GO:0071345 189 0.022
inorganic cation transmembrane transport GO:0098662 207 0.021
mapk cascade GO:0000165 281 0.021
rho protein signal transduction GO:0007266 32 0.021
glucose homeostasis GO:0042593 128 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
response to radiation GO:0009314 165 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
chemotaxis GO:0006935 247 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
transmembrane transport GO:0055085 412 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
cellular chemical homeostasis GO:0055082 215 0.020
t cell differentiation GO:0030217 174 0.020
mrna metabolic process GO:0016071 84 0.020
male gamete generation GO:0048232 285 0.020
sensory perception GO:0007600 245 0.019
meiotic nuclear division GO:0007126 115 0.019
lipid localization GO:0010876 126 0.019
organelle fission GO:0048285 170 0.019
response to peptide GO:1901652 136 0.019
regulation of neuron differentiation GO:0045664 281 0.019
myeloid cell differentiation GO:0030099 233 0.019
protein targeting GO:0006605 143 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
response to light stimulus GO:0009416 135 0.019
intracellular protein transport GO:0006886 204 0.019
nuclear division GO:0000280 158 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.019
cellular homeostasis GO:0019725 240 0.019
compound eye development GO:0048749 1 0.018
actin filament organization GO:0007015 113 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
lipid homeostasis GO:0055088 63 0.018
lipid transport GO:0006869 98 0.018
endomembrane system organization GO:0010256 147 0.018
chromatin modification GO:0016568 187 0.018
oocyte construction GO:0007308 2 0.018
regulation of proteolysis GO:0030162 164 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
response to growth factor GO:0070848 198 0.018
lateral inhibition GO:0046331 1 0.018
negative regulation of cell development GO:0010721 169 0.018
regulation of cytoplasmic transport GO:1903649 112 0.017
oocyte anterior posterior axis specification GO:0007314 2 0.017
muscle system process GO:0003012 141 0.017
regulation of innate immune response GO:0045088 91 0.017
Fly
rna processing GO:0006396 105 0.017
mrna processing GO:0006397 63 0.017
response to inorganic substance GO:0010035 96 0.017
anion transport GO:0006820 177 0.017
regionalization GO:0003002 337 0.017
regulation of hormone levels GO:0010817 211 0.017
peptidyl serine phosphorylation GO:0018105 74 0.017
cellular ion homeostasis GO:0006873 165 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
developmental maturation GO:0021700 193 0.017
regulation of cell migration GO:0030334 219 0.017
regulation of anatomical structure size GO:0090066 178 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.016
sequestering of metal ion GO:0051238 19 0.016
leukocyte proliferation GO:0070661 172 0.016
regulation of protein transport GO:0051223 163 0.016
rna splicing GO:0008380 54 0.016
spermatogenesis GO:0007283 284 0.016
divalent inorganic cation transport GO:0072511 178 0.016
protein processing GO:0016485 163 0.016
peptide transport GO:0015833 133 0.016
response to lipopolysaccharide GO:0032496 128 0.016
cell division GO:0051301 120 0.016
positive regulation of kinase activity GO:0033674 155 0.016
regulation of neuron projection development GO:0010975 169 0.016
nuclear transport GO:0051169 139 0.016
response to oxidative stress GO:0006979 123 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
peptidyl amino acid modification GO:0018193 336 0.016
regulation of t cell differentiation GO:0045580 83 0.016
norepinephrine secretion GO:0048243 2 0.016
positive regulation of cell death GO:0010942 224 0.016
ossification GO:0001503 216 0.016
pallium development GO:0021543 120 0.016
regulation of cellular component biogenesis GO:0044087 181 0.015
negative regulation of protein modification process GO:0031400 163 0.015
organophosphate catabolic process GO:0046434 232 0.015
regulation of cellular component size GO:0032535 121 0.015
retina development in camera type eye GO:0060041 119 0.015
exocytosis GO:0006887 121 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
skin development GO:0043588 220 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
carbohydrate metabolic process GO:0005975 230 0.015
blood circulation GO:0008015 195 0.015
positive regulation of secretion GO:0051047 130 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
regulation of cell projection organization GO:0031344 206 0.015
neuron apoptotic process GO:0051402 142 0.015
adult behavior GO:0030534 135 0.015
response to peptide hormone GO:0043434 127 0.015
regulation of ion transport GO:0043269 215 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
cognition GO:0050890 149 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
multicellular organism growth GO:0035264 161 0.014
immune effector process GO:0002252 321 0.014
glycerolipid metabolic process GO:0046486 122 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of feeding behavior GO:0060259 3 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of neuron death GO:1901214 134 0.014
phospholipid metabolic process GO:0006644 87 0.014
oocyte axis specification GO:0007309 2 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
protein localization to organelle GO:0033365 185 0.014
cell activation involved in immune response GO:0002263 126 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
regulation of multi organism process GO:0043900 111 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of inflammatory response GO:0050727 147 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
defecation GO:0030421 1 0.014
organelle assembly GO:0070925 177 0.014
cell adhesion GO:0007155 329 0.014
neuron migration GO:0001764 122 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
oxidation reduction process GO:0055114 342 0.013
regulation of cell cycle GO:0051726 281 0.013
protein maturation GO:0051604 176 0.013
positive regulation of defense response GO:0031349 124 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
forebrain development GO:0030900 302 0.013
small molecule biosynthetic process GO:0044283 132 0.013
gtp catabolic process GO:0006184 143 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
response to insulin GO:0032868 100 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
vesicle localization GO:0051648 86 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
multi multicellular organism process GO:0044706 109 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
divalent metal ion transport GO:0070838 172 0.013
establishment or maintenance of cell polarity GO:0007163 86 0.013
ear development GO:0043583 200 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
regulation of system process GO:0044057 200 0.013
sulfur compound metabolic process GO:0006790 100 0.013
development of primary sexual characteristics GO:0045137 143 0.013
cellular protein complex assembly GO:0043623 116 0.013
Fly
proteasomal protein catabolic process GO:0010498 98 0.012
negative regulation of organelle organization GO:0010639 90 0.012
cellular response to peptide GO:1901653 92 0.012
cation homeostasis GO:0055080 212 0.012
positive regulation of cell development GO:0010720 237 0.012
negative regulation of cell motility GO:2000146 61 0.012
positive regulation of organelle organization GO:0010638 128 0.012
cell fate commitment GO:0045165 210 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
neuron death GO:0070997 154 0.012
organic hydroxy compound transport GO:0015850 93 0.012
gtp metabolic process GO:0046039 144 0.012
sensory organ morphogenesis GO:0090596 242 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
striated muscle tissue development GO:0014706 293 0.012
inflammatory response GO:0006954 244 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
negative regulation of nervous system development GO:0051961 156 0.012
ribonucleoprotein complex subunit organization GO:0071826 28 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
ameboidal type cell migration GO:0001667 128 0.012
response to oxygen levels GO:0070482 62 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
positive regulation of transferase activity GO:0051347 167 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
innate immune response GO:0045087 157 0.012
Fly
immune response activating signal transduction GO:0002757 116 0.012
metal ion homeostasis GO:0055065 189 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
protein localization to membrane GO:0072657 108 0.012
wound healing GO:0042060 157 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
homeostasis of number of cells GO:0048872 210 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
negative regulation of cell migration GO:0030336 59 0.011
cellular response to lipid GO:0071396 145 0.011
positive regulation of cytokine production GO:0001819 174 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
positive regulation of proteolysis GO:0045862 85 0.011
learning or memory GO:0007611 148 0.011
organic acid biosynthetic process GO:0016053 86 0.011
regulation of homeostatic process GO:0032844 182 0.011
calcium ion transport GO:0006816 159 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of endocytosis GO:0030100 69 0.011
regulation of protein catabolic process GO:0042176 108 0.011
positive regulation of protein transport GO:0051222 93 0.011
lipid biosynthetic process GO:0008610 179 0.011
norepinephrine transport GO:0015874 2 0.011
peptide secretion GO:0002790 114 0.011
muscle cell differentiation GO:0042692 261 0.011
dna metabolic process GO:0006259 303 0.011
regulation of cell shape GO:0008360 39 0.011
regulation of cytokine production GO:0001817 266 0.011
spermatid development GO:0007286 108 0.011
epithelial cell development GO:0002064 159 0.011
anion transmembrane transport GO:0098656 71 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
muscle tissue development GO:0060537 308 0.011
protein ubiquitination GO:0016567 171 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
receptor mediated endocytosis GO:0006898 51 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
protein import into nucleus GO:0006606 95 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
circulatory system process GO:0003013 197 0.011
cytokine production GO:0001816 319 0.011
spermatid differentiation GO:0048515 115 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
t cell differentiation in thymus GO:0033077 77 0.010
meiotic cell cycle GO:0051321 122 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
fatty acid metabolic process GO:0006631 121 0.010
response to decreased oxygen levels GO:0036293 59 0.010
digestive tract development GO:0048565 190 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
leukocyte mediated immunity GO:0002443 174 0.010
regulation of peptide transport GO:0090087 91 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
leukocyte migration GO:0050900 124 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
regulation of rna splicing GO:0043484 37 0.010
glycerolipid biosynthetic process GO:0045017 50 0.010
digestive system development GO:0055123 200 0.010
cell maturation GO:0048469 127 0.010
regulation of blood pressure GO:0008217 93 0.010
regulation of protein maturation GO:1903317 96 0.010
pole plasm assembly GO:0007315 2 0.010
fertilization GO:0009566 127 0.010
sensory system development GO:0048880 3 0.010
neural precursor cell proliferation GO:0061351 121 0.010
stem cell differentiation GO:0048863 268 0.010
stem cell proliferation GO:0072089 117 0.010
female gamete generation GO:0007292 74 0.010
anatomical structure homeostasis GO:0060249 145 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
lymphocyte proliferation GO:0046651 164 0.010
engulfment of apoptotic cell GO:0043652 3 0.010

Unc45a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
disease of metabolism DOID:0014667 0 0.013
disease of mental health DOID:150 0 0.012
central nervous system disease DOID:331 0 0.012