Mus musculus

0 known processes

Polr2e

polymerase (RNA) II (DNA directed) polypeptide E

(Aliases: 2410021N14Rik,RPB5,25kDa,AW208866,XAP4)

Polr2e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.056
cellular amino acid metabolic process GO:0006520 103 0.053
heterocycle catabolic process GO:0046700 280 0.045
rna processing GO:0006396 105 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.041
amine metabolic process GO:0009308 45 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cellular ketone metabolic process GO:0042180 84 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.037
organic cyclic compound catabolic process GO:1901361 295 0.036
aromatic compound catabolic process GO:0019439 286 0.034
purine nucleotide metabolic process GO:0006163 302 0.033
ras protein signal transduction GO:0007265 77 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
peptidyl amino acid modification GO:0018193 336 0.031
nucleotide metabolic process GO:0009117 332 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
small gtpase mediated signal transduction GO:0007264 97 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
purine containing compound metabolic process GO:0072521 311 0.028
regulation of membrane potential GO:0042391 192 0.027
negative regulation of protein metabolic process GO:0051248 282 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.023
macromolecule catabolic process GO:0009057 281 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
organophosphate catabolic process GO:0046434 232 0.023
immune effector process GO:0002252 321 0.022
mrna metabolic process GO:0016071 84 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
nucleotide catabolic process GO:0009166 217 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
nucleoside metabolic process GO:0009116 246 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
mitochondrion organization GO:0007005 134 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
germ cell development GO:0007281 185 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
negative regulation of protein modification process GO:0031400 163 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of hydrolase activity GO:0051336 246 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.018
action potential GO:0001508 78 0.018
cytoplasmic transport GO:0016482 234 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
regulation of cell cycle GO:0051726 281 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
rho protein signal transduction GO:0007266 32 0.018
cytokine production GO:0001816 319 0.018
positive regulation of protein modification process GO:0031401 299 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
intracellular protein transport GO:0006886 204 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
purine containing compound catabolic process GO:0072523 213 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
regulation of organelle organization GO:0033043 289 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
apoptotic signaling pathway GO:0097190 306 0.016
endomembrane system organization GO:0010256 147 0.016
cation transport GO:0006812 399 0.016
nucleoside catabolic process GO:0009164 206 0.016
endocytosis GO:0006897 168 0.016
dna metabolic process GO:0006259 303 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
nucleocytoplasmic transport GO:0006913 139 0.015
regulation of transferase activity GO:0051338 263 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
response to organonitrogen compound GO:0010243 246 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
regulation of proteolysis GO:0030162 164 0.015
translation GO:0006412 93 0.015
carbohydrate metabolic process GO:0005975 230 0.015
regulation of protein localization GO:0032880 231 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
organelle fission GO:0048285 170 0.015
rna splicing GO:0008380 54 0.015
transmission of nerve impulse GO:0019226 76 0.015
response to organic cyclic compound GO:0014070 198 0.015
purine nucleoside catabolic process GO:0006152 205 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
nitrogen compound transport GO:0071705 271 0.014
cellular homeostasis GO:0019725 240 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
gtp catabolic process GO:0006184 143 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
neuronal action potential GO:0019228 54 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of cell activation GO:0050865 289 0.014
oxidation reduction process GO:0055114 342 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
camera type eye development GO:0043010 266 0.014
microtubule based process GO:0007017 236 0.014
protein targeting GO:0006605 143 0.014
multicellular organismal signaling GO:0035637 91 0.014
nuclear transport GO:0051169 139 0.013
membrane organization GO:0061024 245 0.013
protein localization to membrane GO:0072657 108 0.013
sensory perception GO:0007600 245 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
protein ubiquitination GO:0016567 171 0.013
transmembrane transport GO:0055085 412 0.013
nuclear division GO:0000280 158 0.013
regulation of binding GO:0051098 111 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
muscle tissue development GO:0060537 308 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of anatomical structure size GO:0090066 178 0.013
regulation of intracellular transport GO:0032386 159 0.013
cell type specific apoptotic process GO:0097285 268 0.013
sulfur compound metabolic process GO:0006790 100 0.013
cation transmembrane transport GO:0098655 266 0.013
maintenance of location GO:0051235 89 0.013
spermatogenesis GO:0007283 284 0.013
regulation of neuron differentiation GO:0045664 281 0.013
cellular lipid metabolic process GO:0044255 323 0.013
positive regulation of organelle organization GO:0010638 128 0.013
striated muscle tissue development GO:0014706 293 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
regulation of t cell activation GO:0050863 170 0.013
retrograde transport endosome to golgi GO:0042147 2 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
organelle assembly GO:0070925 177 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
covalent chromatin modification GO:0016569 163 0.012
compound eye development GO:0048749 1 0.012
gtp metabolic process GO:0046039 144 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
cellular response to lipid GO:0071396 145 0.012
myosin filament assembly GO:0031034 2 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
cell adhesion GO:0007155 329 0.012
muscle cell differentiation GO:0042692 261 0.012
negative regulation of immune system process GO:0002683 209 0.012
protein localization to organelle GO:0033365 185 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
negative regulation of molecular function GO:0044092 258 0.012
chromatin organization GO:0006325 206 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
anion transport GO:0006820 177 0.011
response to radiation GO:0009314 165 0.011
cofactor metabolic process GO:0051186 80 0.011
regulation of secretion by cell GO:1903530 249 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
positive regulation of cell death GO:0010942 224 0.011
methylation GO:0032259 134 0.011
inflammatory response GO:0006954 244 0.011
response to growth factor GO:0070848 198 0.011
lateral inhibition GO:0046331 1 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
macromolecule methylation GO:0043414 120 0.011
protein maturation GO:0051604 176 0.011
protein secretion GO:0009306 111 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
protein catabolic process GO:0030163 221 0.011
regulation of kinase activity GO:0043549 249 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
synaptic transmission GO:0007268 329 0.011
regulation of hormone levels GO:0010817 211 0.011
regulation of inflammatory response GO:0050727 147 0.011
digestive system development GO:0055123 200 0.011
regulation of protein catabolic process GO:0042176 108 0.011
response to transforming growth factor beta GO:0071559 88 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
regulation of ion transport GO:0043269 215 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
leukocyte proliferation GO:0070661 172 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
response to molecule of bacterial origin GO:0002237 143 0.010
leukocyte differentiation GO:0002521 342 0.010
cell division GO:0051301 120 0.010
asymmetric stem cell division GO:0098722 3 0.010
forebrain development GO:0030900 302 0.010
response to lipopolysaccharide GO:0032496 128 0.010
homeostasis of number of cells GO:0048872 210 0.010
positive regulation of transferase activity GO:0051347 167 0.010
lipid biosynthetic process GO:0008610 179 0.010
histone modification GO:0016570 159 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
chemotaxis GO:0006935 247 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
response to inorganic substance GO:0010035 96 0.010
ion transmembrane transport GO:0034220 361 0.010

Polr2e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.016
disease of anatomical entity DOID:7 0 0.016
hematopoietic system disease DOID:74 0 0.012
disease of cellular proliferation DOID:14566 0 0.012