Mus musculus

31 known processes

Polr2k

polymerase (RNA) II (DNA directed) polypeptide K

(Aliases: MafY,RPABC4,RPB7.0,RPB12,Mt1a,RPB10alpha)

Polr2k biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral inhibition GO:0046331 1 0.263
mitochondrion organization GO:0007005 134 0.094
macromolecule catabolic process GO:0009057 281 0.073
cellular nitrogen compound catabolic process GO:0044270 280 0.068
spermatid differentiation GO:0048515 115 0.067
male gamete generation GO:0048232 285 0.064
cellular macromolecule catabolic process GO:0044265 206 0.053
spermatid development GO:0007286 108 0.051
apoptotic signaling pathway GO:0097190 306 0.044
positive regulation of cell death GO:0010942 224 0.039
spermatogenesis GO:0007283 284 0.035
regulation of hydrolase activity GO:0051336 246 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
protein maturation GO:0051604 176 0.028
oocyte anterior posterior axis specification GO:0007314 2 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
gpi anchor metabolic process GO:0006505 7 0.027
protein processing GO:0016485 163 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
amine metabolic process GO:0009308 45 0.027
aromatic compound catabolic process GO:0019439 286 0.026
cellular amine metabolic process GO:0044106 44 0.026
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
dna metabolic process GO:0006259 303 0.023
positive regulation of apoptotic process GO:0043065 217 0.022
rna splicing GO:0008380 54 0.021
heterocycle catabolic process GO:0046700 280 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
regulation of proteolysis GO:0030162 164 0.020
cellular lipid metabolic process GO:0044255 323 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
single fertilization GO:0007338 82 0.019
cellular ketone metabolic process GO:0042180 84 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
germ cell development GO:0007281 185 0.017
regulation of cellular catabolic process GO:0031329 242 0.016
fertilization GO:0009566 127 0.016
glycerolipid metabolic process GO:0046486 122 0.016
regulation of embryonic development GO:0045995 71 0.016
sensory perception GO:0007600 245 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
forebrain development GO:0030900 302 0.016
rna processing GO:0006396 105 0.015
pole plasm assembly GO:0007315 2 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
membrane lipid metabolic process GO:0006643 53 0.015
gpi anchor biosynthetic process GO:0006506 6 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of organelle organization GO:0033043 289 0.015
purine containing compound metabolic process GO:0072521 311 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
negative regulation of molecular function GO:0044092 258 0.014
mitochondrion morphogenesis GO:0070584 13 0.014
regulation of system process GO:0044057 200 0.014
cell division GO:0051301 120 0.013
cytokinetic process GO:0032506 2 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
gonad development GO:0008406 141 0.013
development of primary sexual characteristics GO:0045137 143 0.013
oocyte axis specification GO:0007309 2 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of kinase activity GO:0033674 155 0.012
regulation of peptidase activity GO:0052547 96 0.012
mapk cascade GO:0000165 281 0.012
positive regulation of endopeptidase activity GO:0010950 43 0.012
cytoplasmic transport GO:0016482 234 0.012
nucleoside metabolic process GO:0009116 246 0.012
peptidyl amino acid modification GO:0018193 336 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
cation transport GO:0006812 399 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
protein catabolic process GO:0030163 221 0.012
cellular protein catabolic process GO:0044257 155 0.011
regulation of binding GO:0051098 111 0.011
protein neddylation GO:0045116 1 0.011
organelle localization GO:0051640 179 0.011
organelle assembly GO:0070925 177 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
microtubule based process GO:0007017 236 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
nucleotide metabolic process GO:0009117 332 0.011
respiratory tube development GO:0030323 167 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
cerebral cortex development GO:0021987 86 0.011
blood circulation GO:0008015 195 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
regulation of cell activation GO:0050865 289 0.010
pallium development GO:0021543 120 0.010
rna catabolic process GO:0006401 29 0.010

Polr2k disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org