Mus musculus

72 known processes

Dbi

diazepam binding inhibitor

(Aliases: endozepine,ACBD1,Acbp,EP)

Dbi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.582
monocarboxylic acid metabolic process GO:0032787 191 0.502
cellular amino acid metabolic process GO:0006520 103 0.260
ribose phosphate metabolic process GO:0019693 291 0.172
myeloid cell differentiation GO:0030099 233 0.145
organic hydroxy compound metabolic process GO:1901615 203 0.144
Human
innate immune response GO:0045087 157 0.143
superoxide metabolic process GO:0006801 27 0.137
aromatic compound catabolic process GO:0019439 286 0.130
purine containing compound metabolic process GO:0072521 311 0.124
cellular lipid metabolic process GO:0044255 323 0.121
fatty acid metabolic process GO:0006631 121 0.108
cellular ketone metabolic process GO:0042180 84 0.107
response to oxygen radical GO:0000305 16 0.105
regulation of protein kinase activity GO:0045859 232 0.099
sulfur compound metabolic process GO:0006790 100 0.094
cellular nitrogen compound catabolic process GO:0044270 280 0.090
spermatogenesis GO:0007283 284 0.088
male gamete generation GO:0048232 285 0.083
ribonucleoside metabolic process GO:0009119 245 0.082
nucleoside catabolic process GO:0009164 206 0.079
amine metabolic process GO:0009308 45 0.078
Human
cellular response to lipopolysaccharide GO:0071222 77 0.078
alpha amino acid metabolic process GO:1901605 59 0.076
nucleobase containing small molecule metabolic process GO:0055086 352 0.075
nucleoside phosphate catabolic process GO:1901292 222 0.075
regulation of response to wounding GO:1903034 189 0.075
purine ribonucleotide metabolic process GO:0009150 290 0.073
glutathione metabolic process GO:0006749 16 0.072
ribonucleotide metabolic process GO:0009259 291 0.072
nucleoside triphosphate metabolic process GO:0009141 230 0.071
dna metabolic process GO:0006259 303 0.071
small molecule biosynthetic process GO:0044283 132 0.070
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
heterocycle catabolic process GO:0046700 280 0.069
cytoplasmic transport GO:0016482 234 0.068
alpha amino acid biosynthetic process GO:1901607 15 0.068
purine nucleotide metabolic process GO:0006163 302 0.068
alcohol metabolic process GO:0006066 116 0.067
Human
cellular modified amino acid metabolic process GO:0006575 63 0.067
regulation of apoptotic signaling pathway GO:2001233 197 0.067
purine ribonucleoside metabolic process GO:0046128 241 0.067
regulation of cellular amine metabolic process GO:0033238 20 0.066
removal of superoxide radicals GO:0019430 12 0.065
cellular response to oxygen radical GO:0071450 14 0.062
cellular aldehyde metabolic process GO:0006081 12 0.059
cellular response to biotic stimulus GO:0071216 92 0.058
nucleoside metabolic process GO:0009116 246 0.058
nucleoside phosphate metabolic process GO:0006753 338 0.057
purine nucleoside metabolic process GO:0042278 241 0.057
cellular amine metabolic process GO:0044106 44 0.056
Human
apoptotic signaling pathway GO:0097190 306 0.056
4 hydroxyproline metabolic process GO:0019471 5 0.055
positive regulation of protein modification process GO:0031401 299 0.054
cellular response to lipid GO:0071396 145 0.053
regulation of hormone levels GO:0010817 211 0.053
organonitrogen compound biosynthetic process GO:1901566 192 0.052
nucleotide catabolic process GO:0009166 217 0.051
response to extracellular stimulus GO:0009991 127 0.051
organonitrogen compound catabolic process GO:1901565 264 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.051
regulation of cellular response to stress GO:0080135 159 0.050
inflammatory response GO:0006954 244 0.050
negative regulation of immune system process GO:0002683 209 0.050
myeloid cell homeostasis GO:0002262 114 0.049
regulation of male germ cell proliferation GO:2000254 3 0.049
purine containing compound catabolic process GO:0072523 213 0.049
protein localization to organelle GO:0033365 185 0.048
response to organic cyclic compound GO:0014070 198 0.047
gland development GO:0048732 330 0.047
nitrogen compound transport GO:0071705 271 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
development of primary male sexual characteristics GO:0046546 88 0.045
response to acid chemical GO:0001101 111 0.045
multicellular organism growth GO:0035264 161 0.045
negative regulation of lymphocyte activation GO:0051250 91 0.044
response to oxidative stress GO:0006979 123 0.044
hormone metabolic process GO:0042445 86 0.043
organic cyclic compound catabolic process GO:1901361 295 0.042
protein maturation GO:0051604 176 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
regulation of protein localization GO:0032880 231 0.042
purine ribonucleotide catabolic process GO:0009154 208 0.041
glycosyl compound metabolic process GO:1901657 246 0.041
purine nucleotide catabolic process GO:0006195 211 0.041
male sex differentiation GO:0046661 109 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
response to superoxide GO:0000303 16 0.039
regulation of intracellular transport GO:0032386 159 0.039
cell aging GO:0007569 35 0.039
cellular homeostasis GO:0019725 240 0.038
nucleotide metabolic process GO:0009117 332 0.038
organic hydroxy compound biosynthetic process GO:1901617 77 0.038
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.037
cellular ion homeostasis GO:0006873 165 0.037
regulation of transferase activity GO:0051338 263 0.037
response to inorganic substance GO:0010035 96 0.036
intrinsic apoptotic signaling pathway GO:0097193 132 0.036
response to lipopolysaccharide GO:0032496 128 0.036
reactive oxygen species metabolic process GO:0072593 84 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
thioester metabolic process GO:0035383 19 0.035
purine ribonucleoside catabolic process GO:0046130 205 0.034
positive regulation of growth GO:0045927 104 0.034
intracellular protein transport GO:0006886 204 0.034
extrinsic apoptotic signaling pathway GO:0097191 126 0.034
regulation of kinase activity GO:0043549 249 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
gonad development GO:0008406 141 0.034
cellular response to extracellular stimulus GO:0031668 81 0.034
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.034
development of primary sexual characteristics GO:0045137 143 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
leukocyte differentiation GO:0002521 342 0.033
homeostasis of number of cells GO:0048872 210 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
regulation of cytoplasmic transport GO:1903649 112 0.033
cellular response to dna damage stimulus GO:0006974 207 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
membrane organization GO:0061024 245 0.032
maintenance of location GO:0051235 89 0.032
retina homeostasis GO:0001895 23 0.032
regulation of defense response GO:0031347 233 0.032
cellular respiration GO:0045333 38 0.032
glutamate biosynthetic process GO:0006537 2 0.032
steroid metabolic process GO:0008202 119 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.031
cellular response to superoxide GO:0071451 14 0.031
metal ion homeostasis GO:0055065 189 0.031
alcohol biosynthetic process GO:0046165 43 0.031
response to molecule of bacterial origin GO:0002237 143 0.031
nuclear transport GO:0051169 139 0.031
response to reactive oxygen species GO:0000302 56 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
cellular response to molecule of bacterial origin GO:0071219 83 0.030
regulation of cell activation GO:0050865 289 0.030
organophosphate catabolic process GO:0046434 232 0.030
tissue homeostasis GO:0001894 115 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
regulation of leukocyte differentiation GO:1902105 159 0.028
positive regulation of protein kinase activity GO:0045860 144 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
positive regulation of kinase activity GO:0033674 155 0.028
regulation of stress activated mapk cascade GO:0032872 69 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
mapk cascade GO:0000165 281 0.027
lipid biosynthetic process GO:0008610 179 0.027
positive regulation of response to wounding GO:1903036 66 0.027
i kappab kinase nf kappab signaling GO:0007249 85 0.026
cation transport GO:0006812 399 0.026
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
transmembrane transport GO:0055085 412 0.026
lipid transport GO:0006869 98 0.025
cellular response to external stimulus GO:0071496 88 0.025
placenta development GO:0001890 140 0.025
peptidyl amino acid modification GO:0018193 336 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
extracellular structure organization GO:0043062 148 0.024
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.024
regulation of protein targeting GO:1903533 61 0.024
regulation of protein transport GO:0051223 163 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
regulation of t cell activation GO:0050863 170 0.024
cellular amide metabolic process GO:0043603 58 0.024
regulation of establishment of protein localization GO:0070201 181 0.023
anion transport GO:0006820 177 0.023
regulation of hydrolase activity GO:0051336 246 0.023
cellular chemical homeostasis GO:0055082 215 0.023
purine nucleoside monophosphate metabolic process GO:0009126 81 0.022
synaptic transmission GO:0007268 329 0.022
organic anion transport GO:0015711 137 0.022
regulation of binding GO:0051098 111 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
negative regulation of multi organism process GO:0043901 68 0.022
acyl coa metabolic process GO:0006637 19 0.022
cytokine production GO:0001816 319 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
lipid localization GO:0010876 126 0.021
amide transport GO:0042886 138 0.021
response to organonitrogen compound GO:0010243 246 0.021
negative regulation of apoptotic signaling pathway GO:2001234 104 0.021
monocarboxylic acid biosynthetic process GO:0072330 61 0.021
cholesterol metabolic process GO:0008203 56 0.021
cholesterol transport GO:0030301 38 0.021
mitochondrion organization GO:0007005 134 0.021
citrate metabolic process GO:0006101 3 0.021
regulation of intracellular protein transport GO:0033157 82 0.020
t cell activation GO:0042110 289 0.020
blood coagulation GO:0007596 76 0.020
small molecule catabolic process GO:0044282 71 0.020
ion transmembrane transport GO:0034220 361 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
regulation of map kinase activity GO:0043405 120 0.020
response to nutrient levels GO:0031667 109 0.020
spermatid development GO:0007286 108 0.020
t cell differentiation GO:0030217 174 0.019
regulation of secretion GO:0051046 274 0.019
lipid modification GO:0030258 65 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
cellular response to oxidative stress GO:0034599 76 0.019
regulation of mapk cascade GO:0043408 248 0.019
lymphocyte proliferation GO:0046651 164 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.019
liver development GO:0001889 66 0.019
hydrogen peroxide catabolic process GO:0042744 5 0.019
protein homooligomerization GO:0051260 43 0.018
regulation of multi organism process GO:0043900 111 0.018
organic acid biosynthetic process GO:0016053 86 0.018
negative regulation of nervous system development GO:0051961 156 0.018
hydrogen peroxide metabolic process GO:0042743 16 0.018
regulation of lymphocyte differentiation GO:0045619 107 0.018
regulation of ion transport GO:0043269 215 0.018
plasma membrane organization GO:0007009 90 0.018
adult behavior GO:0030534 135 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
leukocyte mediated immunity GO:0002443 174 0.018
positive regulation of transferase activity GO:0051347 167 0.018
activation of mapk activity GO:0000187 59 0.018
golgi vesicle transport GO:0048193 30 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
regulation of membrane potential GO:0042391 192 0.017
regulation of nucleocytoplasmic transport GO:0046822 73 0.017
interleukin 8 production GO:0032637 4 0.017
spermatid differentiation GO:0048515 115 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
regulation of secretion by cell GO:1903530 249 0.017
regulation of hemostasis GO:1900046 28 0.017
response to hydrogen peroxide GO:0042542 32 0.016
regulation of phospholipid biosynthetic process GO:0071071 3 0.016
regulation of cytokine production GO:0001817 266 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of organelle organization GO:0033043 289 0.016
cell type specific apoptotic process GO:0097285 268 0.016
negative regulation of t cell activation GO:0050868 65 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
endomembrane system organization GO:0010256 147 0.016
protein import GO:0017038 101 0.016
neuron death GO:0070997 154 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
muscle system process GO:0003012 141 0.016
stress activated mapk cascade GO:0051403 80 0.016
epithelial cell development GO:0002064 159 0.016
wound healing GO:0042060 157 0.016
single organism nuclear import GO:1902593 95 0.015
negative regulation of cell activation GO:0050866 111 0.015
cation transmembrane transport GO:0098655 266 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
leukocyte proliferation GO:0070661 172 0.015
muscle contraction GO:0006936 101 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
regulation of inflammatory response GO:0050727 147 0.015
peptide metabolic process GO:0006518 46 0.015
extracellular matrix organization GO:0030198 147 0.015
positive regulation of map kinase activity GO:0043406 84 0.015
neural precursor cell proliferation GO:0061351 121 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
lipid oxidation GO:0034440 29 0.015
regulation of system process GO:0044057 200 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of blood coagulation GO:0030193 28 0.015
energy derivation by oxidation of organic compounds GO:0015980 77 0.015
inorganic cation transmembrane transport GO:0098662 207 0.014
cellular response to acid chemical GO:0071229 68 0.014
regulation of coagulation GO:0050818 31 0.014
hemostasis GO:0007599 78 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
positive regulation of steroid biosynthetic process GO:0010893 4 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
hepaticobiliary system development GO:0061008 67 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
negative regulation of molecular function GO:0044092 258 0.014
male gonad development GO:0008584 88 0.014
regulation of transmembrane transport GO:0034762 128 0.014
striated muscle tissue development GO:0014706 293 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
lymphocyte differentiation GO:0030098 242 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
protein localization to membrane GO:0072657 108 0.014
sterol metabolic process GO:0016125 58 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
regulation of wound healing GO:0061041 40 0.014
positive regulation of cell death GO:0010942 224 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.013
response to temperature stimulus GO:0009266 55 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
exocytosis GO:0006887 121 0.013
organic hydroxy compound transport GO:0015850 93 0.013
female sex differentiation GO:0046660 84 0.013
action potential GO:0001508 78 0.013
response to steroid hormone GO:0048545 56 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
coagulation GO:0050817 78 0.013
lateral inhibition GO:0046331 1 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
response to oxygen levels GO:0070482 62 0.013
carbohydrate metabolic process GO:0005975 230 0.013
germ cell development GO:0007281 185 0.013
regulation of protein localization to nucleus GO:1900180 60 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
regulation of peptide transport GO:0090087 91 0.013
regulation of removal of superoxide radicals GO:2000121 4 0.013
cell killing GO:0001906 67 0.012
forebrain development GO:0030900 302 0.012
cation homeostasis GO:0055080 212 0.012
mitochondrial transport GO:0006839 36 0.012
muscle tissue development GO:0060537 308 0.012
retinoid metabolic process GO:0001523 24 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
blood circulation GO:0008015 195 0.012
protein import into nucleus GO:0006606 95 0.012
atp metabolic process GO:0046034 75 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
protein localization to nucleus GO:0034504 121 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
regulation of blood pressure GO:0008217 93 0.012
dna recombination GO:0006310 92 0.012
t cell proliferation GO:0042098 120 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
immune effector process GO:0002252 321 0.012
peptidyl serine modification GO:0018209 83 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
nuclear import GO:0051170 95 0.012
production of molecular mediator involved in inflammatory response GO:0002532 21 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
organic acid transport GO:0015849 101 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
peptide transport GO:0015833 133 0.011
protein oligomerization GO:0051259 67 0.011
chromatin disassembly GO:0031498 1 0.011
stem cell proliferation GO:0072089 117 0.011
glucose metabolic process GO:0006006 92 0.011
protein tetramerization GO:0051262 23 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
neuron apoptotic process GO:0051402 142 0.011
circulatory system process GO:0003013 197 0.011
monosaccharide metabolic process GO:0005996 106 0.011
signal transduction in absence of ligand GO:0038034 55 0.011
regulation of anatomical structure size GO:0090066 178 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
dna repair GO:0006281 107 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
atp catabolic process GO:0006200 55 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
cofactor metabolic process GO:0051186 80 0.011
calcium ion homeostasis GO:0055074 127 0.011
regulation of transcription factor import into nucleus GO:0042990 24 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
cellular amino acid biosynthetic process GO:0008652 22 0.011
multicellular organismal aging GO:0010259 24 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
receptor biosynthetic process GO:0032800 3 0.010
regulation of transporter activity GO:0032409 57 0.010
kidney development GO:0001822 213 0.010
primary alcohol metabolic process GO:0034308 11 0.010
diterpenoid metabolic process GO:0016101 24 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
sensory perception GO:0007600 245 0.010
substantia nigra development GO:0021762 2 0.010
glutamine family amino acid biosynthetic process GO:0009084 2 0.010
maternal process involved in female pregnancy GO:0060135 32 0.010
regulation of proteolysis GO:0030162 164 0.010
c21 steroid hormone biosynthetic process GO:0006700 3 0.010
adult locomotory behavior GO:0008344 91 0.010
regulation of body fluid levels GO:0050878 162 0.010

Dbi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.027
disease of metabolism DOID:0014667 0 0.018
cancer DOID:162 0 0.017
central nervous system disease DOID:331 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
inherited metabolic disorder DOID:655 0 0.013