Mus musculus

37 known processes

Hyal4

hyaluronoglucosaminidase 4

(Aliases: 4632428M18Rik)

Hyal4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.169
regulation of cellular amino acid metabolic process GO:0006521 5 0.095
regulation of cellular ketone metabolic process GO:0010565 66 0.094
cellular ketone metabolic process GO:0042180 84 0.088
synaptic transmission GO:0007268 329 0.067
cellular amine metabolic process GO:0044106 44 0.066
organic hydroxy compound metabolic process GO:1901615 203 0.057
transmembrane transport GO:0055085 412 0.057
regulation of cellular amine metabolic process GO:0033238 20 0.054
cellular amino acid metabolic process GO:0006520 103 0.050
carbohydrate metabolic process GO:0005975 230 0.046
lipid biosynthetic process GO:0008610 179 0.045
oxidation reduction process GO:0055114 342 0.045
cellular homeostasis GO:0019725 240 0.045
purine containing compound metabolic process GO:0072521 311 0.043
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
amine metabolic process GO:0009308 45 0.043
small molecule biosynthetic process GO:0044283 132 0.042
ribose phosphate metabolic process GO:0019693 291 0.042
mapk cascade GO:0000165 281 0.040
response to growth factor GO:0070848 198 0.040
steroid metabolic process GO:0008202 119 0.040
alcohol metabolic process GO:0006066 116 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.039
placenta development GO:0001890 140 0.036
cellular response to lipid GO:0071396 145 0.035
g protein coupled receptor signaling pathway GO:0007186 243 0.035
ribonucleotide metabolic process GO:0009259 291 0.033
organic hydroxy compound biosynthetic process GO:1901617 77 0.033
response to organic cyclic compound GO:0014070 198 0.033
response to organonitrogen compound GO:0010243 246 0.032
regulation of secretion GO:0051046 274 0.032
fatty acid metabolic process GO:0006631 121 0.032
embryonic organ morphogenesis GO:0048562 276 0.032
protein catabolic process GO:0030163 221 0.031
nucleotide metabolic process GO:0009117 332 0.031
macromolecule catabolic process GO:0009057 281 0.031
alcohol biosynthetic process GO:0046165 43 0.031
sensory perception GO:0007600 245 0.030
leukocyte differentiation GO:0002521 342 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
lipid localization GO:0010876 126 0.030
bone development GO:0060348 120 0.030
cellular chemical homeostasis GO:0055082 215 0.029
multicellular organismal homeostasis GO:0048871 164 0.029
peptidyl amino acid modification GO:0018193 336 0.029
regulation of protein localization GO:0032880 231 0.029
negative regulation of cellular component organization GO:0051129 194 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.027
memory GO:0007613 58 0.027
regulation of defense response GO:0031347 233 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
regulation of homeostatic process GO:0032844 182 0.026
positive regulation of protein modification process GO:0031401 299 0.026
epidermis development GO:0008544 187 0.026
cellular alcohol biosynthetic process GO:0044108 3 0.026
striated muscle tissue development GO:0014706 293 0.026
calcitriol biosynthetic process from calciol GO:0036378 3 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
cytokine production GO:0001816 319 0.025
rho protein signal transduction GO:0007266 32 0.025
maintenance of location GO:0051235 89 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
divalent metal ion transport GO:0070838 172 0.025
male gamete generation GO:0048232 285 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
response to peptide hormone GO:0043434 127 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
calcium ion homeostasis GO:0055074 127 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
anion transport GO:0006820 177 0.024
skin development GO:0043588 220 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
cellular response to peptide hormone stimulus GO:0071375 92 0.024
developmental growth involved in morphogenesis GO:0060560 138 0.023
myeloid cell differentiation GO:0030099 233 0.023
forebrain development GO:0030900 302 0.023
lipid homeostasis GO:0055088 63 0.023
muscle tissue development GO:0060537 308 0.023
regulation of cytokine production GO:0001817 266 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
cellular alcohol metabolic process GO:0044107 3 0.023
fertilization GO:0009566 127 0.023
Mouse
vitamin d3 metabolic process GO:0070640 3 0.023
ossification GO:0001503 216 0.023
skeletal muscle organ development GO:0060538 163 0.023
nitrogen compound transport GO:0071705 271 0.022
learning or memory GO:0007611 148 0.022
innate immune response GO:0045087 157 0.022
myeloid leukocyte differentiation GO:0002573 119 0.022
calcium ion transport GO:0006816 159 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
cation homeostasis GO:0055080 212 0.021
regulation of transferase activity GO:0051338 263 0.021
cation transmembrane transport GO:0098655 266 0.021
mitral valve development GO:0003174 4 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
regulation of cell cycle process GO:0010564 160 0.020
anatomical structure homeostasis GO:0060249 145 0.020
ameboidal type cell migration GO:0001667 128 0.020
protein ubiquitination GO:0016567 171 0.020
ion transmembrane transport GO:0034220 361 0.020
negative regulation of protein modification process GO:0031400 163 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
naphthalene metabolic process GO:0018931 1 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
skeletal system morphogenesis GO:0048705 203 0.019
negative regulation of molecular function GO:0044092 258 0.019
camera type eye development GO:0043010 266 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
positive regulation of cell death GO:0010942 224 0.019
secondary alcohol metabolic process GO:1902652 3 0.019
glucose homeostasis GO:0042593 128 0.019
skeletal system development GO:0001501 356 0.019
sterol metabolic process GO:0016125 58 0.019
regulation of transforming growth factor beta secretion GO:2001201 1 0.019
intracellular receptor signaling pathway GO:0030522 74 0.019
response to acid chemical GO:0001101 111 0.019
blood vessel morphogenesis GO:0048514 285 0.019
spermatogenesis GO:0007283 284 0.019
immune effector process GO:0002252 321 0.019
regulation of cell projection organization GO:0031344 206 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
response to inorganic substance GO:0010035 96 0.018
fat cell differentiation GO:0045444 160 0.018
regulation of secretion by cell GO:1903530 249 0.018
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.018
naphthalene containing compound metabolic process GO:0090420 1 0.018
apoptotic signaling pathway GO:0097190 306 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
negative regulation of cell development GO:0010721 169 0.018
cytoplasmic transport GO:0016482 234 0.018
wnt signaling pathway GO:0016055 188 0.018
sensory organ morphogenesis GO:0090596 242 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
cellular ion homeostasis GO:0006873 165 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
response to peptide GO:1901652 136 0.018
tissue homeostasis GO:0001894 115 0.017
wound healing GO:0042060 157 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
angiogenesis GO:0001525 201 0.017
carbohydrate homeostasis GO:0033500 128 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
regulation of protein transport GO:0051223 163 0.017
synapse organization GO:0050808 125 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of mapk cascade GO:0043408 248 0.017
dna metabolic process GO:0006259 303 0.017
ear development GO:0043583 200 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
lipid transport GO:0006869 98 0.017
regulation of erk1 and erk2 cascade GO:0070372 71 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
cartilage development GO:0051216 140 0.016
somatotropin secreting cell differentiation GO:0060126 4 0.016
erk1 and erk2 cascade GO:0070371 77 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
cognition GO:0050890 149 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
energy derivation by oxidation of organic compounds GO:0015980 77 0.016
transforming growth factor beta secretion GO:0038044 1 0.016
regulation of hydrolase activity GO:0051336 246 0.016
inflammatory response GO:0006954 244 0.016
regulation of interleukin 10 secretion GO:2001179 4 0.016
regulation of response to wounding GO:1903034 189 0.016
regulation of cell cycle GO:0051726 281 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
sequestering of calcium ion GO:0051208 18 0.016
organic anion transport GO:0015711 137 0.016
nucleoside metabolic process GO:0009116 246 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
divalent inorganic cation transport GO:0072511 178 0.016
heterocycle catabolic process GO:0046700 280 0.016
positive regulation of cytokine production GO:0001819 174 0.016
regionalization GO:0003002 337 0.016
vitamin metabolic process GO:0006766 23 0.015
metal ion homeostasis GO:0055065 189 0.015
negative regulation of nervous system development GO:0051961 156 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
axonogenesis GO:0007409 274 0.015
regulation of organelle organization GO:0033043 289 0.015
locomotory behavior GO:0007626 195 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
nuclear division GO:0000280 158 0.015
vitamin d biosynthetic process GO:0042368 3 0.015
organelle fission GO:0048285 170 0.015
cell adhesion GO:0007155 329 0.015
fat soluble vitamin biosynthetic process GO:0042362 4 0.015
response to testosterone GO:0033574 3 0.015
regulation of cell activation GO:0050865 289 0.015
regulation of ossification GO:0030278 112 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of feeding behavior GO:0060259 3 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.015
regulation of cell adhesion GO:0030155 154 0.015
protein maturation GO:0051604 176 0.015
regulation of cellular response to stress GO:0080135 159 0.015
regulation of binding GO:0051098 111 0.015
cellular response to inorganic substance GO:0071241 37 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
cellular protein catabolic process GO:0044257 155 0.014
negative regulation of cell cycle GO:0045786 123 0.014
multi multicellular organism process GO:0044706 109 0.014
Mouse
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.014
regulation of muscle tissue development GO:1901861 97 0.014
lymphocyte differentiation GO:0030098 242 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
respiratory tube development GO:0030323 167 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
lung development GO:0030324 164 0.014
sequestering of metal ion GO:0051238 19 0.014
positive regulation of cell development GO:0010720 237 0.014
regulation of protein kinase activity GO:0045859 232 0.014
defense response to other organism GO:0098542 197 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
amide transport GO:0042886 138 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
cyclic nucleotide metabolic process GO:0009187 59 0.013
nucleoside catabolic process GO:0009164 206 0.013
cation transport GO:0006812 399 0.013
insulin secretion GO:0030073 89 0.013
homeostasis of number of cells GO:0048872 210 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
interleukin 10 secretion GO:0072608 4 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
protein localization to nucleus GO:0034504 121 0.013
protein kinase b signaling GO:0043491 74 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
epithelial cell proliferation GO:0050673 174 0.013
chromatin organization GO:0006325 206 0.013
regulation of reproductive process GO:2000241 66 0.013
meiotic cell cycle GO:0051321 122 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
telencephalon development GO:0021537 186 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
aromatic compound catabolic process GO:0019439 286 0.013
cardiac muscle tissue development GO:0048738 130 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
glycoprotein metabolic process GO:0009100 116 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
muscle cell differentiation GO:0042692 261 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
cellular response to steroid hormone stimulus GO:0071383 33 0.012
regulation of interleukin 8 secretion GO:2000482 2 0.012
positive regulation of cell activation GO:0050867 158 0.012
sulfur compound metabolic process GO:0006790 100 0.012
regulation of neuron projection development GO:0010975 169 0.012
appendage development GO:0048736 166 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
protein localization to organelle GO:0033365 185 0.012
covalent chromatin modification GO:0016569 163 0.012
connective tissue development GO:0061448 179 0.012
cofactor metabolic process GO:0051186 80 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
negative regulation of ossification GO:0030279 49 0.012
histone modification GO:0016570 159 0.012
positive regulation of defense response GO:0031349 124 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of ion transport GO:0043269 215 0.012
monosaccharide metabolic process GO:0005996 106 0.012
cell type specific apoptotic process GO:0097285 268 0.012
regulation of hormone levels GO:0010817 211 0.012
negative regulation of defense response GO:0031348 77 0.012
thermosensory behavior GO:0040040 1 0.012
extracellular structure organization GO:0043062 148 0.012
drug catabolic process GO:0042737 2 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
respiratory system development GO:0060541 190 0.012
cellular response to peptide GO:1901653 92 0.011
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.011
inter male aggressive behavior GO:0002121 3 0.011
meiotic nuclear division GO:0007126 115 0.011
negative regulation of cell growth GO:0030308 44 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
regulation of system process GO:0044057 200 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
response to radiation GO:0009314 165 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
leukocyte migration GO:0050900 124 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
rhythmic process GO:0048511 174 0.011
limb development GO:0060173 166 0.011
cell growth GO:0016049 130 0.011
chondrocyte differentiation GO:0002062 72 0.011
cellular response to metal ion GO:0071248 31 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
mitotic cell cycle process GO:1903047 159 0.011
mitochondrion organization GO:0007005 134 0.011
cell division GO:0051301 120 0.011
palate development GO:0060021 76 0.011
extracellular matrix organization GO:0030198 147 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
response to transforming growth factor beta GO:0071559 88 0.011
digestive tract morphogenesis GO:0048546 147 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of myeloid leukocyte differentiation GO:0002761 58 0.010
positive regulation of nervous system development GO:0051962 221 0.010
exogenous drug catabolic process GO:0042738 1 0.010
gonad development GO:0008406 141 0.010
t cell differentiation GO:0030217 174 0.010
protein localization to membrane GO:0072657 108 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
chromatin modification GO:0016568 187 0.010
defense response to bacterium GO:0042742 119 0.010
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.010
developmental maturation GO:0021700 193 0.010
mitochondrion distribution GO:0048311 4 0.010
keratinocyte differentiation GO:0030216 48 0.010
cellular response to acid chemical GO:0071229 68 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
regulation of intracellular transport GO:0032386 159 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
hormone secretion GO:0046879 128 0.010
endomembrane system organization GO:0010256 147 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
negative regulation of growth GO:0045926 99 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
dephosphorylation GO:0016311 129 0.010
hepaticobiliary system development GO:0061008 67 0.010
organic cyclic compound catabolic process GO:1901361 295 0.010
purine containing compound catabolic process GO:0072523 213 0.010

Hyal4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.010