|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.886
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.884
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.863
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.832
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.780
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.778
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.773
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.681
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.655
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.622
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.605
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.549
|
Yeast |
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.537
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.527
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.523
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.512
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.472
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.464
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.450
|
Yeast Mouse Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.442
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.424
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.410
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.403
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.391
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.385
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.382
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.382
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.381
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.360
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.349
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.335
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.331
|
Human Mouse Rat Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.322
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.322
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.321
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.318
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.317
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.296
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.289
|
Rat |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.264
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.257
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.251
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.235
|
|
|
|
intra golgi vesicle mediated transport
|
GO:0006891 |
1 |
0.235
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.232
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.226
|
Human |
|
|
rab protein signal transduction
|
GO:0032482 |
1 |
0.224
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.218
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.218
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.215
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.215
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.207
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.201
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.197
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.197
|
Fly |
|
|
melanosome localization
|
GO:0032400 |
12 |
0.196
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.196
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.194
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.194
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.182
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.180
|
Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.178
|
|
|
|
centrosome separation
|
GO:0051299 |
4 |
0.173
|
|
|
|
negative regulation of calcium ion dependent exocytosis
|
GO:0045955 |
3 |
0.172
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.164
|
Human Yeast Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.162
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.161
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.156
|
|
|
|
phospholipid dephosphorylation
|
GO:0046839 |
6 |
0.153
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.151
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.149
|
|
|
|
intracellular lipid transport
|
GO:0032365 |
3 |
0.142
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.142
|
Rat |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.134
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.132
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.131
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.125
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.124
|
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
39 |
0.123
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.123
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.123
|
Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.121
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.121
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.121
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.115
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.114
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.114
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.110
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.104
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.104
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.103
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.101
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.099
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.099
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.096
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.096
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.096
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.095
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.092
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.091
|
Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.091
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.090
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.087
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.087
|
|
|
|
establishment of protein localization to golgi
|
GO:0072600 |
1 |
0.086
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.086
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.085
|
Human Mouse Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.081
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.081
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.080
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.080
|
|
|
|
virion assembly
|
GO:0019068 |
1 |
0.079
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.077
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.075
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.075
|
Rat |
|
|
exosomal secretion
|
GO:1990182 |
1 |
0.074
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.074
|
|
|
|
centrosome cycle
|
GO:0007098 |
23 |
0.072
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.072
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.072
|
|
|
|
regulation of cytoplasmic translation
|
GO:2000765 |
4 |
0.072
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.070
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.069
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.069
|
|
|
|
formation of organ boundary
|
GO:0010160 |
1 |
0.069
|
|
|
|
negative regulation of purine nucleotide catabolic process
|
GO:0033122 |
9 |
0.068
|
|
|
|
synaptonemal complex organization
|
GO:0070193 |
15 |
0.068
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.068
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.067
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.067
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.065
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.064
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.064
|
Human Mouse Fly |
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.064
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.063
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.061
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.061
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.060
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.060
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.060
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.058
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.058
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.058
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.058
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.058
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.058
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.057
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.057
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.057
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.056
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.055
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.054
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.054
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.054
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.053
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.053
|
Fly |
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
3 |
0.052
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.052
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.051
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.051
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.051
|
Mouse |
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.050
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.050
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.049
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.049
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.049
|
|
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
3 |
0.049
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.048
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.048
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.047
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.047
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.047
|
|
|
|
positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway
|
GO:1902237 |
3 |
0.047
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.046
|
Yeast |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.046
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.046
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.045
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.044
|
Yeast |
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.044
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
13 |
0.044
|
Yeast |
|
|
regulation of vacuole organization
|
GO:0044088 |
4 |
0.043
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.043
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.043
|
Fly |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.042
|
Human |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.042
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.042
|
Yeast |
|
|
autophagy
|
GO:0006914 |
45 |
0.042
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.042
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.041
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.041
|
|
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.041
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.041
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.040
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.040
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.040
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.039
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.039
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.039
|
|
|
|
adherens junction maintenance
|
GO:0034334 |
1 |
0.038
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.038
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.038
|
Mouse Fly |
|
|
stem cell development
|
GO:0048864 |
219 |
0.037
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.037
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.037
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.036
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.036
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.036
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.036
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.036
|
|
|
|
protein neddylation
|
GO:0045116 |
1 |
0.035
|
|
|
|
positive regulation of dendrite development
|
GO:1900006 |
21 |
0.035
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.035
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.034
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.034
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.034
|
Fly |
|
|
establishment of tissue polarity
|
GO:0007164 |
28 |
0.034
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.033
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.033
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.032
|
Rat |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.032
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.032
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.032
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.031
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.031
|
|
|
|
establishment of pigment granule localization
|
GO:0051905 |
12 |
0.031
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.031
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.031
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
6 |
0.031
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.030
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.030
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.030
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.030
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.030
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
45 |
0.030
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.030
|
Human |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.030
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.029
|
Fly |
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
3 |
0.029
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.029
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.029
|
Fly |
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.029
|
|
|
|
endoplasmic reticulum organization
|
GO:0007029 |
10 |
0.028
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.028
|
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.028
|
Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.028
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.028
|
|
|
|
positive regulation of rac protein signal transduction
|
GO:0035022 |
1 |
0.028
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.028
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.028
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.027
|
Rat |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.027
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.027
|
|
|
|
phosphatidylethanolamine metabolic process
|
GO:0046337 |
2 |
0.027
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.027
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.026
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.026
|
|
|
|
dendritic cell proliferation
|
GO:0044565 |
2 |
0.026
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.026
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.026
|
|
|
|
positive regulation of tor signaling
|
GO:0032008 |
3 |
0.026
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.025
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.025
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.025
|
Human Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.025
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.025
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.025
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.024
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.024
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.024
|
|
|
|
regulation of calcium ion dependent exocytosis
|
GO:0017158 |
16 |
0.024
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.024
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.024
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.024
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.024
|
|
|
|
establishment of melanosome localization
|
GO:0032401 |
11 |
0.024
|
Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.024
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.023
|
Human |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.023
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.023
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.023
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.023
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.023
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.023
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.023
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.023
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.023
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.023
|
Yeast |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.023
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.022
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.022
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
6 |
0.022
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.022
|
|
|
|
growth plate cartilage chondrocyte growth
|
GO:0003430 |
2 |
0.022
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.022
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.022
|
|
|
|
regulation of er to golgi vesicle mediated transport
|
GO:0060628 |
4 |
0.022
|
|
|
|
positive regulation of atpase activity
|
GO:0032781 |
3 |
0.021
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
7 |
0.021
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.021
|
|
|
|
vacuole organization
|
GO:0007033 |
38 |
0.021
|
Yeast |
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.021
|
|
|
|
retrograde transport vesicle recycling within golgi
|
GO:0000301 |
1 |
0.021
|
|
|
|
regulation of endocytic recycling
|
GO:2001135 |
3 |
0.021
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.021
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.020
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.020
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.020
|
|
|
|
embryonic axis specification
|
GO:0000578 |
30 |
0.020
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.020
|
Human Mouse Fly |
|
|
segmentation
|
GO:0035282 |
93 |
0.020
|
Fly |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.020
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.020
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.020
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.020
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.020
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.019
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.019
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.019
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.019
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.019
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.019
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.019
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.019
|
|
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
13 |
0.019
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.019
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.019
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.019
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.019
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.019
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.019
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.019
|
|
|
|
vesicle docking
|
GO:0048278 |
7 |
0.019
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.019
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.019
|
Mouse |
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.019
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.018
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.018
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.018
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.018
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.018
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.018
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.018
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.018
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
21 |
0.018
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.018
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.018
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.018
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.018
|
|
|
|
transforming growth factor beta2 production
|
GO:0032906 |
2 |
0.017
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.017
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.017
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.017
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.017
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.017
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.017
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.017
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.017
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.017
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.017
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.017
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.017
|
|
|
|
axon target recognition
|
GO:0007412 |
4 |
0.017
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.017
|
|
|
|
vesicle docking involved in exocytosis
|
GO:0006904 |
7 |
0.017
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.017
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.017
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.016
|
|
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
10 |
0.016
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.016
|
|
|
|
centrosome organization
|
GO:0051297 |
26 |
0.016
|
|
|
|
trna wobble uridine modification
|
GO:0002098 |
2 |
0.016
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
17 |
0.016
|
|
|
|
positive regulation of transcription from rna polymerase i promoter
|
GO:0045943 |
3 |
0.016
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.016
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.016
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.016
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.016
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.016
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.016
|
|
|
|
glycerophospholipid catabolic process
|
GO:0046475 |
5 |
0.016
|
|
|
|
regulation of angiotensin metabolic process
|
GO:0060177 |
4 |
0.016
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.016
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.016
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.016
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.016
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.015
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.015
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.015
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.015
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.015
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.015
|
Fly |
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
27 |
0.015
|
|
|
|
toxin transport
|
GO:1901998 |
38 |
0.015
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.015
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.015
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.015
|
|
|
|
negative regulation of transporter activity
|
GO:0032410 |
7 |
0.015
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.015
|
Human Mouse Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.015
|
|
|
|
positive regulation of sequestering of triglyceride
|
GO:0010890 |
4 |
0.015
|
|
|
|
nucleotide transmembrane transport
|
GO:1901679 |
2 |
0.015
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.015
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.015
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.015
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.015
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.014
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.014
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.014
|
|
|
|
cholesterol transport
|
GO:0030301 |
38 |
0.014
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.014
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.014
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.014
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.014
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.014
|
|
|
|
positive regulation of long term neuronal synaptic plasticity
|
GO:0048170 |
3 |
0.014
|
|
|
|
endosome organization
|
GO:0007032 |
9 |
0.014
|
Yeast Mouse Rat |
|
|
golgi vesicle transport
|
GO:0048193 |
30 |
0.014
|
Yeast |
|
|
innate immune response
|
GO:0045087 |
157 |
0.014
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.014
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.014
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.014
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.014
|
Fly |
|
|
regulation of mrna polyadenylation
|
GO:1900363 |
1 |
0.014
|
|
|
|
cellular polysaccharide catabolic process
|
GO:0044247 |
5 |
0.014
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.014
|
|
|
|
negative regulation of calcium ion transmembrane transport
|
GO:1903170 |
1 |
0.014
|
|
|
|
regulation of glutamate receptor signaling pathway
|
GO:1900449 |
16 |
0.014
|
|
|
|
regulation of atp metabolic process
|
GO:1903578 |
17 |
0.014
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.013
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.013
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
13 |
0.013
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.013
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.013
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.013
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.013
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
15 |
0.013
|
|
|
|
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045899 |
2 |
0.013
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.013
|
|
|
|
synapsis
|
GO:0007129 |
34 |
0.013
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.013
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.013
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.013
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.013
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.013
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.013
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
5 |
0.013
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.013
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
23 |
0.013
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.012
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.012
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.012
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.012
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.012
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.012
|
Human Mouse |
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
1 |
0.012
|
|
|
|
peroxisomal transport
|
GO:0043574 |
4 |
0.012
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.012
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.012
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.012
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.012
|
|
|
|
cardiac muscle hypertrophy in response to stress
|
GO:0014898 |
10 |
0.012
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.012
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.012
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.012
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.012
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.012
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.012
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.012
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.012
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.012
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.012
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.012
|
|
|
|
receptor recycling
|
GO:0001881 |
11 |
0.011
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.011
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
3 |
0.011
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.011
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.011
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.011
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.011
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.011
|
|
|
|
negative regulation of calcium ion transmembrane transporter activity
|
GO:1901020 |
1 |
0.011
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.011
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.011
|
|
|
|
leukocyte tethering or rolling
|
GO:0050901 |
3 |
0.011
|
|
|
|
cell cycle switching
|
GO:0060184 |
1 |
0.011
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.011
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.011
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.011
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.011
|
|
|
|
protein retention in golgi apparatus
|
GO:0045053 |
1 |
0.011
|
|