Mus musculus

39 known processes

Pion

pigeon homolog (Drosophila)

(Aliases: A530088I07Rik,GSAP)

Pion biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipopolysaccharide GO:0071222 77 0.314
response to molecule of bacterial origin GO:0002237 143 0.235
innate immune response GO:0045087 157 0.229
immune effector process GO:0002252 321 0.204
regulation of cytokine production GO:0001817 266 0.200
cytokine production GO:0001816 319 0.190
cellular response to molecule of bacterial origin GO:0071219 83 0.186
regulation of defense response GO:0031347 233 0.180
activation of innate immune response GO:0002218 56 0.177
regulation of innate immune response GO:0045088 91 0.173
positive regulation of cytokine production GO:0001819 174 0.172
cellular response to biotic stimulus GO:0071216 92 0.141
cellular response to lipid GO:0071396 145 0.141
defense response to other organism GO:0098542 197 0.129
leukocyte activation involved in immune response GO:0002366 126 0.123
ras protein signal transduction GO:0007265 77 0.121
small gtpase mediated signal transduction GO:0007264 97 0.119
cellular nitrogen compound catabolic process GO:0044270 280 0.111
positive regulation of innate immune response GO:0045089 80 0.108
regulation of leukocyte mediated immunity GO:0002703 104 0.108
response to lipopolysaccharide GO:0032496 128 0.107
t cell differentiation GO:0030217 174 0.107
regulation of hydrolase activity GO:0051336 246 0.105
myeloid cell differentiation GO:0030099 233 0.102
heterocycle catabolic process GO:0046700 280 0.099
amine metabolic process GO:0009308 45 0.099
t cell activation GO:0042110 289 0.098
regulation of cell activation GO:0050865 289 0.094
activation of immune response GO:0002253 138 0.094
immune response regulating signaling pathway GO:0002764 125 0.094
reactive oxygen species metabolic process GO:0072593 84 0.092
regulation of protein localization GO:0032880 231 0.090
defense response to bacterium GO:0042742 119 0.088
positive regulation of defense response GO:0031349 124 0.088
cellular amino acid metabolic process GO:0006520 103 0.088
inflammatory response GO:0006954 244 0.083
leukocyte mediated immunity GO:0002443 174 0.083
carbohydrate derivative catabolic process GO:1901136 231 0.082
rho protein signal transduction GO:0007266 32 0.082
purine nucleotide catabolic process GO:0006195 211 0.081
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.080
negative regulation of phosphorus metabolic process GO:0010563 184 0.080
purine ribonucleoside catabolic process GO:0046130 205 0.080
leukocyte proliferation GO:0070661 172 0.080
mapk cascade GO:0000165 281 0.079
aromatic compound catabolic process GO:0019439 286 0.079
immune response activating signal transduction GO:0002757 116 0.078
leukocyte differentiation GO:0002521 342 0.078
regulation of cellular ketone metabolic process GO:0010565 66 0.077
negative regulation of protein metabolic process GO:0051248 282 0.077
cell activation involved in immune response GO:0002263 126 0.077
positive regulation of immune effector process GO:0002699 107 0.076
myeloid leukocyte differentiation GO:0002573 119 0.074
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.074
positive regulation of cell activation GO:0050867 158 0.072
glycosyl compound catabolic process GO:1901658 206 0.071
regulation of cellular amine metabolic process GO:0033238 20 0.070
regulation of mapk cascade GO:0043408 248 0.070
nucleotide metabolic process GO:0009117 332 0.069
nucleotide catabolic process GO:0009166 217 0.068
ribonucleoside triphosphate metabolic process GO:0009199 220 0.065
purine ribonucleoside metabolic process GO:0046128 241 0.064
regulation of secretion GO:0051046 274 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.063
cellular amine metabolic process GO:0044106 44 0.063
gtp catabolic process GO:0006184 143 0.063
nucleoside phosphate metabolic process GO:0006753 338 0.063
nucleoside metabolic process GO:0009116 246 0.063
purine nucleoside triphosphate metabolic process GO:0009144 226 0.063
nucleoside catabolic process GO:0009164 206 0.063
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.062
ribonucleoside triphosphate catabolic process GO:0009203 199 0.061
negative regulation of immune system process GO:0002683 209 0.061
negative regulation of cellular component organization GO:0051129 194 0.060
regulation of interferon gamma production GO:0032649 57 0.059
regulation of cell motility GO:2000145 236 0.059
positive regulation of protein modification process GO:0031401 299 0.059
reactive oxygen species biosynthetic process GO:1903409 8 0.059
regulation of lymphocyte activation GO:0051249 240 0.059
regulation of ras protein signal transduction GO:0046578 114 0.058
reactive nitrogen species metabolic process GO:2001057 0 0.058
organic cyclic compound catabolic process GO:1901361 295 0.057
organonitrogen compound catabolic process GO:1901565 264 0.057
ribonucleoside metabolic process GO:0009119 245 0.057
g protein coupled receptor signaling pathway GO:0007186 243 0.057
toll like receptor signaling pathway GO:0002224 38 0.056
protein localization to organelle GO:0033365 185 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.056
cytoplasmic transport GO:0016482 234 0.055
protein modification by small protein conjugation GO:0032446 187 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
negative regulation of phosphorylation GO:0042326 166 0.055
pattern recognition receptor signaling pathway GO:0002221 47 0.055
ribose phosphate metabolic process GO:0019693 291 0.054
organophosphate catabolic process GO:0046434 232 0.054
ribonucleotide metabolic process GO:0009259 291 0.054
positive regulation of hydrolase activity GO:0051345 148 0.053
guanosine containing compound catabolic process GO:1901069 144 0.053
regulation of leukocyte proliferation GO:0070663 121 0.052
regulation of interleukin 6 production GO:0032675 55 0.052
glycosyl compound metabolic process GO:1901657 246 0.052
cation transport GO:0006812 399 0.052
guanosine containing compound metabolic process GO:1901068 144 0.051
positive regulation of protein transport GO:0051222 93 0.051
positive regulation of mapk cascade GO:0043410 170 0.051
ribonucleoside catabolic process GO:0042454 206 0.051
purine containing compound catabolic process GO:0072523 213 0.051
purine nucleoside metabolic process GO:0042278 241 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.050
regulation of establishment of protein localization GO:0070201 181 0.050
lymphocyte differentiation GO:0030098 242 0.050
negative regulation of phosphate metabolic process GO:0045936 184 0.050
positive regulation of protein phosphorylation GO:0001934 242 0.050
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.050
apoptotic signaling pathway GO:0097190 306 0.049
purine containing compound metabolic process GO:0072521 311 0.049
gtp metabolic process GO:0046039 144 0.049
regulation of cell migration GO:0030334 219 0.049
regulation of inflammatory response GO:0050727 147 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
regulation of lymphocyte proliferation GO:0050670 117 0.048
ribonucleotide catabolic process GO:0009261 208 0.047
regulation of response to wounding GO:1903034 189 0.047
regulation of secretion by cell GO:1903530 249 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.046
organic hydroxy compound metabolic process GO:1901615 203 0.046
regulation of transferase activity GO:0051338 263 0.046
purine nucleoside triphosphate catabolic process GO:0009146 203 0.046
interferon gamma production GO:0032609 67 0.045
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.045
regulation of reactive oxygen species metabolic process GO:2000377 40 0.045
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.044
lymphocyte proliferation GO:0046651 164 0.044
chemotaxis GO:0006935 247 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.043
regulation of neuron differentiation GO:0045664 281 0.043
cellular ketone metabolic process GO:0042180 84 0.043
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
regulation of cellular catabolic process GO:0031329 242 0.043
myeloid leukocyte activation GO:0002274 83 0.043
alpha beta t cell activation GO:0046631 91 0.042
cellular response to cytokine stimulus GO:0071345 189 0.042
negative regulation of intracellular signal transduction GO:1902532 167 0.042
innate immune response activating signal transduction GO:0002758 50 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.042
b cell activation GO:0042113 161 0.041
regulation of rho protein signal transduction GO:0035023 71 0.041
purine ribonucleotide catabolic process GO:0009154 208 0.041
nitrogen compound transport GO:0071705 271 0.040
regulation of t cell activation GO:0050863 170 0.040
regulation of gtp catabolic process GO:0033124 113 0.040
protein secretion GO:0009306 111 0.040
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.039
positive regulation of gtpase activity GO:0043547 85 0.039
leukocyte migration GO:0050900 124 0.039
regulation of purine nucleotide catabolic process GO:0033121 122 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
positive regulation of cell development GO:0010720 237 0.039
extrinsic apoptotic signaling pathway GO:0097191 126 0.039
wound healing GO:0042060 157 0.039
regulation of nucleotide catabolic process GO:0030811 122 0.039
regulation of protein kinase activity GO:0045859 232 0.039
i kappab kinase nf kappab signaling GO:0007249 85 0.038
response to organonitrogen compound GO:0010243 246 0.038
nucleoside phosphate catabolic process GO:1901292 222 0.038
negative regulation of protein phosphorylation GO:0001933 126 0.037
muscle cell differentiation GO:0042692 261 0.037
peptidyl amino acid modification GO:0018193 336 0.037
leukocyte mediated cytotoxicity GO:0001909 62 0.037
lymphocyte activation involved in immune response GO:0002285 93 0.037
positive regulation of gtp catabolic process GO:0033126 85 0.036
regulation of multi organism process GO:0043900 111 0.036
multicellular organismal homeostasis GO:0048871 164 0.035
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.035
regulation of apoptotic signaling pathway GO:2001233 197 0.035
divalent inorganic cation transport GO:0072511 178 0.035
regulation of kinase activity GO:0043549 249 0.035
transmembrane transport GO:0055085 412 0.035
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
regulation of cytoskeleton organization GO:0051493 122 0.034
positive regulation of lymphocyte proliferation GO:0050671 70 0.034
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.034
regulation of protein transport GO:0051223 163 0.033
hematopoietic progenitor cell differentiation GO:0002244 143 0.033
negative regulation of cell activation GO:0050866 111 0.033
regulation of cellular response to stress GO:0080135 159 0.033
interleukin 6 production GO:0032635 58 0.033
regulation of t cell proliferation GO:0042129 92 0.033
protein localization to nucleus GO:0034504 121 0.033
endocytosis GO:0006897 168 0.033
regulation of ras gtpase activity GO:0032318 88 0.033
protein catabolic process GO:0030163 221 0.033
positive regulation of cell killing GO:0031343 33 0.033
membrane organization GO:0061024 245 0.032
defense response to gram positive bacterium GO:0050830 50 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.032
ossification GO:0001503 216 0.032
cellular homeostasis GO:0019725 240 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.032
axonogenesis GO:0007409 274 0.032
cellular lipid metabolic process GO:0044255 323 0.031
sequestering of calcium ion GO:0051208 18 0.031
positive regulation of leukocyte proliferation GO:0070665 73 0.031
blood vessel morphogenesis GO:0048514 285 0.031
cell type specific apoptotic process GO:0097285 268 0.031
regulation of vesicle mediated transport GO:0060627 139 0.031
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.031
positive regulation of transferase activity GO:0051347 167 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
regulation of organelle organization GO:0033043 289 0.030
cytokine mediated signaling pathway GO:0019221 115 0.030
regulation of response to biotic stimulus GO:0002831 38 0.030
positive regulation of kinase activity GO:0033674 155 0.030
regulation of nucleotide metabolic process GO:0006140 169 0.030
interspecies interaction between organisms GO:0044419 83 0.029
establishment of protein localization to organelle GO:0072594 118 0.029
regulation of intracellular transport GO:0032386 159 0.029
t cell proliferation GO:0042098 120 0.029
regulation of leukocyte differentiation GO:1902105 159 0.029
positive regulation of cell migration GO:0030335 109 0.029
cell adhesion GO:0007155 329 0.029
ion transmembrane transport GO:0034220 361 0.029
cell chemotaxis GO:0060326 81 0.028
forebrain development GO:0030900 302 0.028
regulation of rho gtpase activity GO:0032319 58 0.028
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.028
anion transport GO:0006820 177 0.028
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.028
exocytosis GO:0006887 121 0.028
negative regulation of molecular function GO:0044092 258 0.028
regulation of ion transport GO:0043269 215 0.028
neuron migration GO:0001764 122 0.027
multicellular organismal signaling GO:0035637 91 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
divalent metal ion transport GO:0070838 172 0.027
cytokine biosynthetic process GO:0042089 68 0.027
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.027
regulation of cytokine biosynthetic process GO:0042035 59 0.027
positive regulation of rho gtpase activity GO:0032321 41 0.027
regulation of proteolysis GO:0030162 164 0.027
gland development GO:0048732 330 0.026
negative regulation of protein modification process GO:0031400 163 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.026
macromolecule catabolic process GO:0009057 281 0.026
defense response to virus GO:0051607 68 0.026
positive regulation of secretion GO:0051047 130 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
regulation of nucleoside metabolic process GO:0009118 130 0.026
positive regulation of nervous system development GO:0051962 221 0.026
positive regulation of secretion by cell GO:1903532 114 0.026
erk1 and erk2 cascade GO:0070371 77 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
sequestering of metal ion GO:0051238 19 0.026
regulation of map kinase activity GO:0043405 120 0.026
negative regulation of nervous system development GO:0051961 156 0.026
cell killing GO:0001906 67 0.026
regulation of cell killing GO:0031341 40 0.025
regulation of b cell activation GO:0050864 81 0.025
positive regulation of interferon gamma production GO:0032729 39 0.025
positive regulation of protein kinase activity GO:0045860 144 0.025
myeloid leukocyte migration GO:0097529 57 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
placenta development GO:0001890 140 0.025
negative regulation of cytokine production GO:0001818 84 0.025
positive regulation of cell death GO:0010942 224 0.025
positive regulation of ras gtpase activity GO:0032320 65 0.025
natural killer cell activation GO:0030101 44 0.025
cytokine secretion GO:0050663 72 0.025
regulation of cell projection organization GO:0031344 206 0.025
homeostasis of number of cells GO:0048872 210 0.024
adaptive immune response GO:0002250 155 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
organelle localization GO:0051640 179 0.024
positive regulation of map kinase activity GO:0043406 84 0.024
intracellular protein transport GO:0006886 204 0.024
organic anion transport GO:0015711 137 0.024
regulation of interferon beta biosynthetic process GO:0045357 4 0.024
dna metabolic process GO:0006259 303 0.024
interferon beta biosynthetic process GO:0045350 4 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
antigen receptor mediated signaling pathway GO:0050851 64 0.024
morphogenesis of a branching structure GO:0001763 203 0.024
protein import GO:0017038 101 0.023
negative regulation of defense response GO:0031348 77 0.023
positive regulation of lymphocyte activation GO:0051251 140 0.023
morphogenesis of a branching epithelium GO:0061138 193 0.023
nuclear transport GO:0051169 139 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.023
regulation of protein complex assembly GO:0043254 83 0.023
cellular response to peptidoglycan GO:0071224 4 0.023
actin filament organization GO:0007015 113 0.023
calcium ion homeostasis GO:0055074 127 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
regulation of cell cycle GO:0051726 281 0.023
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.022
positive regulation of leukocyte mediated immunity GO:0002705 70 0.022
anatomical structure homeostasis GO:0060249 145 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
regulation of protein catabolic process GO:0042176 108 0.022
blood coagulation GO:0007596 76 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
positive regulation of organelle organization GO:0010638 128 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
cation transmembrane transport GO:0098655 266 0.022
muscle tissue development GO:0060537 308 0.022
cytokine metabolic process GO:0042107 71 0.022
sensory perception GO:0007600 245 0.022
regulation of lymphocyte mediated immunity GO:0002706 84 0.022
regulation of erk1 and erk2 cascade GO:0070372 71 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
cell recognition GO:0008037 83 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
negative regulation of cell development GO:0010721 169 0.021
small molecule biosynthetic process GO:0044283 132 0.021
regulation of cytoplasmic transport GO:1903649 112 0.021
lipid localization GO:0010876 126 0.021
cellular chemical homeostasis GO:0055082 215 0.021
nuclear import GO:0051170 95 0.021
single organism cell adhesion GO:0098602 156 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
protein maturation GO:0051604 176 0.021
metal ion homeostasis GO:0055065 189 0.021
carboxylic acid transport GO:0046942 100 0.021
cellular ion homeostasis GO:0006873 165 0.021
alcohol metabolic process GO:0006066 116 0.020
regulation of actin filament based process GO:0032970 99 0.020
protein ubiquitination GO:0016567 171 0.020
b cell activation involved in immune response GO:0002312 50 0.020
epithelial cell proliferation GO:0050673 174 0.020
stress activated protein kinase signaling cascade GO:0031098 81 0.020
regulation of cytokine secretion GO:0050707 61 0.020
tissue homeostasis GO:0001894 115 0.020
regulation of membrane potential GO:0042391 192 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
regulation of interleukin 2 production GO:0032663 28 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
protein kinase b signaling GO:0043491 74 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
detection of fungus GO:0016046 2 0.019
production of molecular mediator of immune response GO:0002440 103 0.019
regulation of body fluid levels GO:0050878 162 0.019
glial cell differentiation GO:0010001 131 0.019
positive regulation of b cell activation GO:0050871 49 0.019
regulation of homeostatic process GO:0032844 182 0.019
transmission of nerve impulse GO:0019226 76 0.019
tissue remodeling GO:0048771 102 0.019
actin cytoskeleton organization GO:0030036 220 0.019
amide transport GO:0042886 138 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
positive regulation of cytokine biosynthetic process GO:0042108 40 0.019
regulation of peptidase activity GO:0052547 96 0.019
response to acid chemical GO:0001101 111 0.019
positive regulation of cell motility GO:2000147 116 0.019
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.019
t cell receptor signaling pathway GO:0050852 46 0.018
regulation of t cell differentiation GO:0045580 83 0.018
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.018
detection of stimulus GO:0051606 84 0.018
oxidation reduction process GO:0055114 342 0.018
regulation of anatomical structure size GO:0090066 178 0.018
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.018
t cell activation involved in immune response GO:0002286 43 0.018
regulation of cell adhesion GO:0030155 154 0.018
positive regulation of nucleotide catabolic process GO:0030813 88 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.018
regulation of endocytosis GO:0030100 69 0.018
response to organic cyclic compound GO:0014070 198 0.018
positive regulation of t cell activation GO:0050870 101 0.018
calcium ion transport GO:0006816 159 0.018
negative regulation of secretion by cell GO:1903531 54 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
single organism nuclear import GO:1902593 95 0.017
stem cell differentiation GO:0048863 268 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
leukocyte chemotaxis GO:0030595 69 0.017
peptide transport GO:0015833 133 0.017
regulation of adaptive immune response GO:0002819 90 0.017
negative regulation of growth GO:0045926 99 0.017
regulation of protein secretion GO:0050708 82 0.017
neural tube development GO:0021915 160 0.017
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.017
wnt signaling pathway GO:0016055 188 0.017
myotube differentiation GO:0014902 105 0.017
hemostasis GO:0007599 78 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
detection of biotic stimulus GO:0009595 10 0.017
intracellular receptor signaling pathway GO:0030522 74 0.017
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.017
organic acid transport GO:0015849 101 0.017
b cell proliferation GO:0042100 53 0.017
positive regulation of leukocyte differentiation GO:1902107 86 0.017
skeletal muscle organ development GO:0060538 163 0.017
regulation of stress activated mapk cascade GO:0032872 69 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.016
protein processing GO:0016485 163 0.016
response to peptide GO:1901652 136 0.016
chemokine production GO:0032602 34 0.016
cognition GO:0050890 149 0.016
regulation of neuron projection development GO:0010975 169 0.016
phagocytosis GO:0006909 66 0.016
fat cell differentiation GO:0045444 160 0.016
monocyte extravasation GO:0035696 2 0.016
extracellular matrix organization GO:0030198 147 0.016
positive regulation of interleukin 6 production GO:0032755 37 0.016
signal transduction in absence of ligand GO:0038034 55 0.016
regulation of toll like receptor signaling pathway GO:0034121 20 0.016
glucose homeostasis GO:0042593 128 0.016
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.016
protein import into nucleus GO:0006606 95 0.016
positive regulation of stress activated mapk cascade GO:0032874 48 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
neuronal action potential GO:0019228 54 0.016
regulation of immunological synapse formation GO:2000520 2 0.016
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.016
angiogenesis GO:0001525 201 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
bone remodeling GO:0046849 53 0.015
skin development GO:0043588 220 0.015
positive regulation of t cell extravasation GO:2000409 2 0.015
cation homeostasis GO:0055080 212 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
positive regulation of cytokine secretion GO:0050715 41 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
activation of mapk activity GO:0000187 59 0.015
regulation of nucleocytoplasmic transport GO:0046822 73 0.015
glycoprotein metabolic process GO:0009100 116 0.015
protein polymerization GO:0051258 57 0.015
interleukin 8 production GO:0032637 4 0.015
positive regulation of protein secretion GO:0050714 52 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
positive regulation of monocyte extravasation GO:2000439 1 0.015
protein targeting GO:0006605 143 0.015
regulation of hormone levels GO:0010817 211 0.015
skeletal system development GO:0001501 356 0.015
lipid transport GO:0006869 98 0.015
osteoclast differentiation GO:0030316 62 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
regulation of monocyte extravasation GO:2000437 2 0.015
positive regulation of protein catabolic process GO:0045732 60 0.015
negative regulation of synapse assembly GO:0051964 3 0.015
regulation of t cell extravasation GO:2000407 3 0.015
regulation of ion homeostasis GO:2000021 64 0.015
response to growth factor GO:0070848 198 0.015
microglia development GO:0014005 2 0.015
positive regulation of interferon alpha production GO:0032727 4 0.014
regulation of protein targeting GO:1903533 61 0.014
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.014
renal system development GO:0072001 225 0.014
positive regulation of proteolysis GO:0045862 85 0.014
regulation of system process GO:0044057 200 0.014
developmental maturation GO:0021700 193 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
endomembrane system organization GO:0010256 147 0.014
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.014
synaptic transmission GO:0007268 329 0.014
cellularization GO:0007349 1 0.014
action potential GO:0001508 78 0.014
cell substrate adhesion GO:0031589 130 0.014
response to molecule of fungal origin GO:0002238 4 0.014
eosinophil activation GO:0043307 1 0.014
type i interferon production GO:0032606 29 0.014
regulation of production of molecular mediator of immune response GO:0002700 65 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
stress activated mapk cascade GO:0051403 80 0.014
regulation of chemokine production GO:0032642 30 0.014
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
kidney development GO:0001822 213 0.013
muscle system process GO:0003012 141 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
extracellular structure organization GO:0043062 148 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.013
detection of molecule of bacterial origin GO:0032490 2 0.013
neuron death GO:0070997 154 0.013
neuron apoptotic process GO:0051402 142 0.013
alpha beta t cell differentiation GO:0046632 69 0.013
myeloid leukocyte mediated immunity GO:0002444 42 0.013
phosphatidylinositol mediated signaling GO:0048015 41 0.013

Pion disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.016
disease of metabolism DOID:0014667 0 0.013