Mus musculus

60 known processes

Ppp2r1a

protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform

(Aliases: PR65,6330556D22Rik,PP2A)

Ppp2r1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric neuroblast division GO:0055059 1 0.930
asymmetric stem cell division GO:0098722 3 0.817
thermosensory behavior GO:0040040 1 0.795
microtubule cytoskeleton organization GO:0000226 157 0.782
meiotic cell cycle GO:0051321 122 0.674
oocyte axis specification GO:0007309 2 0.645
oocyte anterior posterior axis specification GO:0007314 2 0.645
oocyte construction GO:0007308 2 0.604
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.592
microtubule based process GO:0007017 236 0.568
establishment or maintenance of cell polarity GO:0007163 86 0.560
intracellular protein transport GO:0006886 204 0.543
cation transport GO:0006812 399 0.533
pole plasm assembly GO:0007315 2 0.507
cell division GO:0051301 120 0.506
protein complex disassembly GO:0043241 40 0.498
cytokinesis GO:0000910 17 0.492
germ cell development GO:0007281 185 0.450
dephosphorylation GO:0016311 129 0.447
oocyte differentiation GO:0009994 35 0.441
ras protein signal transduction GO:0007265 77 0.439
modification dependent protein catabolic process GO:0019941 133 0.432
centriole assembly GO:0098534 6 0.420
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.410
regulation of intracellular transport GO:0032386 159 0.409
meiotic nuclear division GO:0007126 115 0.404
cellular protein catabolic process GO:0044257 155 0.402
cell adhesion GO:0007155 329 0.398
organelle disassembly GO:1903008 2 0.393
meiotic cell cycle process GO:1903046 77 0.392
organelle assembly GO:0070925 177 0.361
proteasomal protein catabolic process GO:0010498 98 0.354
organelle localization GO:0051640 179 0.348
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.338
synaptic transmission GO:0007268 329 0.327
divalent metal ion transport GO:0070838 172 0.325
positive regulation of programmed cell death GO:0043068 218 0.323
cellular macromolecule catabolic process GO:0044265 206 0.316
nucleocytoplasmic transport GO:0006913 139 0.313
regulation of ion transmembrane transporter activity GO:0032412 54 0.312
sarcomere organization GO:0045214 24 0.310
regulation of cell shape GO:0008360 39 0.306
nucleotide metabolic process GO:0009117 332 0.305
positive regulation of protein kinase activity GO:0045860 144 0.305
fertilization GO:0009566 127 0.299
cytoplasmic transport GO:0016482 234 0.288
regulation of cytoplasmic transport GO:1903649 112 0.285
protein catabolic process GO:0030163 221 0.273
positive regulation of transferase activity GO:0051347 167 0.272
cellular response to ethanol GO:0071361 3 0.271
developmental maturation GO:0021700 193 0.270
spindle localization GO:0051653 22 0.267
regulation of circadian sleep wake cycle GO:0042749 3 0.257
regulation of epidermal cell division GO:0010482 3 0.256
nuclear transport GO:0051169 139 0.253
intracellular mrna localization GO:0008298 4 0.250
response to organonitrogen compound GO:0010243 246 0.248
protein depolymerization GO:0051261 34 0.246
smoothened signaling pathway GO:0007224 105 0.244
protein autophosphorylation GO:0046777 61 0.243
macromolecular complex disassembly GO:0032984 43 0.241
calcium ion transport GO:0006816 159 0.241
actin filament organization GO:0007015 113 0.231
cellular response to dna damage stimulus GO:0006974 207 0.231
regulation of nucleocytoplasmic transport GO:0046822 73 0.231
regulation of smoothened signaling pathway GO:0008589 58 0.230
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.221
endomembrane system organization GO:0010256 147 0.214
cellular response to monosaccharide stimulus GO:0071326 47 0.210
cellular chemical homeostasis GO:0055082 215 0.210
mitotic cell cycle process GO:1903047 159 0.209
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.208
regulation of establishment of protein localization GO:0070201 181 0.207
regulation of proteolysis GO:0030162 164 0.205
establishment of spindle localization GO:0051293 19 0.203
divalent inorganic cation transport GO:0072511 178 0.202
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.200
regulation of proteasomal protein catabolic process GO:0061136 46 0.200
regulation of receptor activity GO:0010469 41 0.199
stem cell proliferation GO:0072089 117 0.199
regulation of protein localization GO:0032880 231 0.198
regulation of protein catabolic process GO:0042176 108 0.198
striated muscle cell development GO:0055002 125 0.189
membrane organization GO:0061024 245 0.187
regulation of protein transport GO:0051223 163 0.187
positive regulation of protein export from nucleus GO:0046827 4 0.185
myosin filament assembly GO:0031034 2 0.185
macromolecule catabolic process GO:0009057 281 0.184
nuclear envelope organization GO:0006998 11 0.180
hatching GO:0035188 4 0.179
dna repair GO:0006281 107 0.177
muscle cell development GO:0055001 133 0.176
actin cytoskeleton organization GO:0030036 220 0.172
nucleus localization GO:0051647 20 0.171
actomyosin structure organization GO:0031032 56 0.168
multicellular organismal reproductive behavior GO:0033057 23 0.166
organelle fission GO:0048285 170 0.163
plasma membrane organization GO:0007009 90 0.162
spindle organization GO:0007051 28 0.162
positive regulation of apoptotic process GO:0043065 217 0.161
establishment of protein localization to organelle GO:0072594 118 0.161
oogenesis GO:0048477 56 0.160
transmembrane transport GO:0055085 412 0.158
spindle assembly GO:0051225 13 0.157
regulation of meiotic cell cycle GO:0051445 34 0.156
muscle cell differentiation GO:0042692 261 0.156
multi organism behavior GO:0051705 62 0.156
regulation of protein binding GO:0043393 60 0.154
regulation of ion transport GO:0043269 215 0.154
regulation of transferase activity GO:0051338 263 0.154
nuclear division GO:0000280 158 0.154
positive regulation of proteolysis GO:0045862 85 0.152
negative regulation of nervous system development GO:0051961 156 0.150
cell fate commitment GO:0045165 210 0.149
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.147
organism emergence from protective structure GO:0071684 4 0.147
regulation of synaptic plasticity GO:0048167 87 0.146
ion transmembrane transport GO:0034220 361 0.146
stem cell differentiation GO:0048863 268 0.142
protein import into nucleus GO:0006606 95 0.142
multi multicellular organism process GO:0044706 109 0.141
purine nucleoside triphosphate metabolic process GO:0009144 226 0.140
protein targeting GO:0006605 143 0.140
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.139
heterocycle catabolic process GO:0046700 280 0.139
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.139
epidermal cell division GO:0010481 3 0.138
female gamete generation GO:0007292 74 0.137
cellular response to lipid GO:0071396 145 0.137
cellular component assembly involved in morphogenesis GO:0010927 139 0.137
regulation of cell cycle GO:0051726 281 0.137
cation transmembrane transport GO:0098655 266 0.136
positive regulation of protein modification process GO:0031401 299 0.135
protein localization to plasma membrane GO:0072659 57 0.135
calcium ion transmembrane transport GO:0070588 85 0.134
inorganic ion transmembrane transport GO:0098660 234 0.134
cellular homeostasis GO:0019725 240 0.133
cellular response to hexose stimulus GO:0071331 47 0.133
regulation of protein kinase activity GO:0045859 232 0.133
cellular glucose homeostasis GO:0001678 52 0.132
spermatogenesis GO:0007283 284 0.130
regulation of circadian rhythm GO:0042752 58 0.130
molting cycle GO:0042303 90 0.130
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.129
inorganic cation transmembrane transport GO:0098662 207 0.129
divalent inorganic cation homeostasis GO:0072507 138 0.127
cellular response to misfolded protein GO:0071218 5 0.127
small gtpase mediated signal transduction GO:0007264 97 0.126
purine ribonucleoside catabolic process GO:0046130 205 0.124
striated muscle myosin thick filament assembly GO:0071688 1 0.123
axonogenesis GO:0007409 274 0.123
protein oligomerization GO:0051259 67 0.121
modification dependent macromolecule catabolic process GO:0043632 133 0.121
anatomical structure homeostasis GO:0060249 145 0.121
meiotic spindle organization GO:0000212 9 0.121
maternal determination of anterior posterior axis embryo GO:0008358 2 0.118
response to endoplasmic reticulum stress GO:0034976 53 0.117
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.117
response to monosaccharide GO:0034284 67 0.117
neuronal stem cell division GO:0036445 10 0.116
regulation of ligase activity GO:0051340 10 0.115
canonical wnt signaling pathway GO:0060070 130 0.114
coagulation GO:0050817 78 0.114
glucose homeostasis GO:0042593 128 0.113
mitotic cell cycle GO:0000278 195 0.112
myofibril assembly GO:0030239 34 0.112
negative regulation of cell cycle GO:0045786 123 0.111
myosin filament organization GO:0031033 3 0.111
nucleoside phosphate catabolic process GO:1901292 222 0.110
neuroblast division GO:0055057 10 0.109
negative regulation of cell development GO:0010721 169 0.109
camera type eye development GO:0043010 266 0.108
cell maturation GO:0048469 127 0.108
positive regulation of protein phosphorylation GO:0001934 242 0.107
cellular response to carbohydrate stimulus GO:0071322 50 0.107
establishment of epithelial cell polarity GO:0090162 10 0.106
response to organic cyclic compound GO:0014070 198 0.106
muscle system process GO:0003012 141 0.105
regulation of cellular protein catabolic process GO:1903362 61 0.105
development of primary sexual characteristics GO:0045137 143 0.104
regulation of cellular component biogenesis GO:0044087 181 0.103
calcium ion homeostasis GO:0055074 127 0.103
nucleoside phosphate metabolic process GO:0006753 338 0.102
cellular response to glucose stimulus GO:0071333 45 0.102
cellular response to organic cyclic compound GO:0071407 87 0.100
epithelial tube morphogenesis GO:0060562 303 0.100
regulation of calcium ion transport GO:0051924 69 0.099
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.099
negative regulation of calcium ion transmembrane transport GO:1903170 1 0.098
response to parathyroid hormone GO:0071107 3 0.098
positive regulation of oocyte development GO:0060282 4 0.097
centrosome separation GO:0051299 4 0.097
regulation of metal ion transport GO:0010959 106 0.097
reproductive behavior GO:0019098 32 0.096
protein localization to nucleus GO:0034504 121 0.095
mapk cascade GO:0000165 281 0.095
nucleobase containing small molecule metabolic process GO:0055086 352 0.094
synaptic vesicle localization GO:0097479 59 0.094
autophagy GO:0006914 45 0.094
regulation of protein serine threonine kinase activity GO:0071900 157 0.094
positive regulation of cell death GO:0010942 224 0.093
cellular response to cytokine stimulus GO:0071345 189 0.093
spermatid differentiation GO:0048515 115 0.092
regulation of ion transmembrane transport GO:0034765 119 0.092
spermatid development GO:0007286 108 0.090
negative regulation of cellular protein metabolic process GO:0032269 247 0.090
ribonucleotide catabolic process GO:0009261 208 0.089
neurotransmitter transport GO:0006836 76 0.088
regulation of neuron differentiation GO:0045664 281 0.088
receptor mediated endocytosis GO:0006898 51 0.088
neural precursor cell proliferation GO:0061351 121 0.087
regulation of cell division GO:0051302 76 0.087
cellular response to gonadotropin stimulus GO:0071371 4 0.087
chromosome segregation GO:0007059 48 0.086
Human
ribonucleoside monophosphate catabolic process GO:0009158 57 0.086
centrosome cycle GO:0007098 23 0.085
negative regulation of phosphorylation GO:0042326 166 0.085
negative regulation of protein metabolic process GO:0051248 282 0.085
regulation of organelle organization GO:0033043 289 0.084
atp catabolic process GO:0006200 55 0.084
histone modification GO:0016570 159 0.083
purine containing compound metabolic process GO:0072521 311 0.083
regulation of actin cytoskeleton organization GO:0032956 84 0.083
nucleoside triphosphate catabolic process GO:0009143 205 0.082
multicellular organismal homeostasis GO:0048871 164 0.082
response to temperature stimulus GO:0009266 55 0.082
regulation of cell cycle process GO:0010564 160 0.081
organophosphate catabolic process GO:0046434 232 0.081
smooth muscle contraction GO:0006939 44 0.081
hormone metabolic process GO:0042445 86 0.080
nucleoside triphosphate metabolic process GO:0009141 230 0.080
cardiac muscle tissue development GO:0048738 130 0.080
mitotic cytokinesis GO:0000281 4 0.080
regulation of transcription factor import into nucleus GO:0042990 24 0.079
positive regulation of dephosphorylation GO:0035306 6 0.078
cellular response to hormone stimulus GO:0032870 150 0.078
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.078
cellular response to inorganic substance GO:0071241 37 0.077
cellular response to organonitrogen compound GO:0071417 145 0.077
regulation of tight junction assembly GO:2000810 2 0.077
regulation of membrane potential GO:0042391 192 0.077
regulation of homeostatic process GO:0032844 182 0.076
regulation of intracellular protein transport GO:0033157 82 0.076
regulation of kinase activity GO:0043549 249 0.076
oocyte development GO:0048599 33 0.075
negative regulation of protein dephosphorylation GO:0035308 2 0.074
positive regulation of cellular protein catabolic process GO:1903364 34 0.074
neural tube formation GO:0001841 108 0.074
carbohydrate derivative catabolic process GO:1901136 231 0.073
response to calcium ion GO:0051592 20 0.073
positive regulation of mapk cascade GO:0043410 170 0.073
nuclear import GO:0051170 95 0.072
muscle fiber development GO:0048747 76 0.072
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.071
purine nucleoside triphosphate catabolic process GO:0009146 203 0.071
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.071
peptidyl amino acid modification GO:0018193 336 0.071
positive regulation of kinase activity GO:0033674 155 0.070
regulation of protein import into nucleus GO:0042306 52 0.070
regulation of stem cell proliferation GO:0072091 78 0.070
regulation of cellular response to stress GO:0080135 159 0.070
keratinocyte development GO:0003334 10 0.069
male gamete generation GO:0048232 285 0.069
negative regulation of cell proliferation GO:0008285 296 0.069
establishment of synaptic vesicle localization GO:0097480 57 0.069
aggresome assembly GO:0070842 2 0.069
actin filament polymerization GO:0030041 44 0.068
positive regulation of organelle organization GO:0010638 128 0.068
protein localization to organelle GO:0033365 185 0.068
synapse organization GO:0050808 125 0.068
cellular response to insulin stimulus GO:0032869 78 0.068
regulation of cell projection organization GO:0031344 206 0.068
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.067
neuron projection guidance GO:0097485 141 0.067
protein ubiquitination GO:0016567 171 0.067
regulation of secretion GO:0051046 274 0.066
cellular ion homeostasis GO:0006873 165 0.066
negative regulation of molecular function GO:0044092 258 0.065
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
glycosyl compound catabolic process GO:1901658 206 0.065
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.065
ubiquitin dependent protein catabolic process GO:0006511 129 0.065
regulation of protein targeting GO:1903533 61 0.064
regulation of hormone levels GO:0010817 211 0.064
protein import GO:0017038 101 0.064
neuroblast proliferation GO:0007405 49 0.064
cellular response to steroid hormone stimulus GO:0071383 33 0.064
carbohydrate homeostasis GO:0033500 128 0.063
nucleoside monophosphate catabolic process GO:0009125 59 0.063
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.063
neural tube development GO:0021915 160 0.063
establishment of organelle localization GO:0051656 122 0.062
sensory perception GO:0007600 245 0.062
positive regulation of phosphoprotein phosphatase activity GO:0032516 1 0.061
cellular response to parathyroid hormone stimulus GO:0071374 2 0.061
genitalia development GO:0048806 37 0.061
cellular nitrogen compound catabolic process GO:0044270 280 0.061
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.061
regulation of secretion by cell GO:1903530 249 0.060
transmission of nerve impulse GO:0019226 76 0.060
stem cell development GO:0048864 219 0.060
positive regulation of protein transport GO:0051222 93 0.060
regulation of protein localization to nucleus GO:1900180 60 0.059
actin polymerization or depolymerization GO:0008154 54 0.059
inclusion body assembly GO:0070841 3 0.059
cell cell junction assembly GO:0007043 27 0.059
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.059
metal ion homeostasis GO:0055065 189 0.058
regulation of transporter activity GO:0032409 57 0.058
purine ribonucleotide metabolic process GO:0009150 290 0.058
ribose phosphate metabolic process GO:0019693 291 0.057
retina development in camera type eye GO:0060041 119 0.057
stem cell division GO:0017145 30 0.057
cellular response to topologically incorrect protein GO:0035967 25 0.057
purine ribonucleoside metabolic process GO:0046128 241 0.057
microtubule organizing center organization GO:0031023 28 0.057
mesenchyme development GO:0060485 152 0.057
regulation of transposition GO:0010528 2 0.057
purine nucleoside catabolic process GO:0006152 205 0.056
nucleoside metabolic process GO:0009116 246 0.056
cellular protein complex disassembly GO:0043624 36 0.056
olfactory learning GO:0008355 2 0.056
organic cyclic compound catabolic process GO:1901361 295 0.056
protein export from nucleus GO:0006611 20 0.056
multicellular organismal signaling GO:0035637 91 0.056
mitotic nuclear division GO:0007067 48 0.056
negative regulation of protein transport GO:0051224 46 0.055
cellular ketone metabolic process GO:0042180 84 0.055
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.055
regulation of protein dephosphorylation GO:0035304 4 0.055
ribonucleoside triphosphate metabolic process GO:0009199 220 0.055
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.055
regulation of hydrolase activity GO:0051336 246 0.055
zygote asymmetric cell division GO:0010070 2 0.054
response to insulin GO:0032868 100 0.054
positive regulation of smoothened signaling pathway GO:0045880 23 0.054
regulation of neuron projection development GO:0010975 169 0.054
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.053
response to peptide GO:1901652 136 0.053
sperm capacitation GO:0048240 17 0.053
hemostasis GO:0007599 78 0.053
establishment of vesicle localization GO:0051650 81 0.053
negative regulation of protein modification process GO:0031400 163 0.052
cellular calcium ion homeostasis GO:0006874 119 0.052
regulation of protein maturation GO:1903317 96 0.052
regulation of neural precursor cell proliferation GO:2000177 70 0.052
regulation of protein depolymerization GO:1901879 26 0.051
regionalization GO:0003002 337 0.051
actin filament based movement GO:0030048 23 0.051
cognition GO:0050890 149 0.051
regulation of neuroblast proliferation GO:1902692 27 0.049
positive regulation of protein complex assembly GO:0031334 45 0.049
regulation of ubiquitin protein transferase activity GO:0051438 7 0.049
embryonic epithelial tube formation GO:0001838 130 0.049
negative regulation of intracellular protein transport GO:0090317 27 0.049
regulation of neurotransmitter secretion GO:0046928 29 0.049
wnt signaling pathway GO:0016055 188 0.049
regulation of actin nucleation GO:0051125 4 0.049
organonitrogen compound catabolic process GO:1901565 264 0.049
dendritic spine organization GO:0097061 26 0.049
regulation of actin filament polymerization GO:0030833 38 0.048
positive regulation of nervous system development GO:0051962 221 0.048
multicellular organism growth GO:0035264 161 0.048
neuron migration GO:0001764 122 0.048
cellular protein complex assembly GO:0043623 116 0.047
positive regulation of cell motility GO:2000147 116 0.047
positive regulation of phosphatase activity GO:0010922 4 0.047
regulation of neurotransmitter levels GO:0001505 87 0.047
atp metabolic process GO:0046034 75 0.047
positive regulation of cytoplasmic transport GO:1903651 40 0.047
peptidyl serine phosphorylation GO:0018105 74 0.046
negative regulation of cell size GO:0045792 3 0.046
response to metal ion GO:0010038 47 0.046
regulation of lipid metabolic process GO:0019216 118 0.046
response to inorganic substance GO:0010035 96 0.046
dna metabolic process GO:0006259 303 0.046
steroid metabolic process GO:0008202 119 0.045
regulation of cellular catabolic process GO:0031329 242 0.045
single fertilization GO:0007338 82 0.045
regulation of vesicle mediated transport GO:0060627 139 0.045
protein modification by small protein conjugation GO:0032446 187 0.044
gland development GO:0048732 330 0.044
protein localization to membrane GO:0072657 108 0.044
primary neural tube formation GO:0014020 95 0.044
centrosome duplication GO:0051298 16 0.043
positive regulation of protein catabolic process GO:0045732 60 0.043
protein kinase a signaling GO:0010737 7 0.043
circadian rhythm GO:0007623 114 0.043
cellular divalent inorganic cation homeostasis GO:0072503 127 0.043
regulation of binding GO:0051098 111 0.043
skeletal myofibril assembly GO:0014866 4 0.043
tissue homeostasis GO:0001894 115 0.042
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.042
sensory organ morphogenesis GO:0090596 242 0.042
cell cycle arrest GO:0007050 37 0.042
vesicle localization GO:0051648 86 0.042
positive regulation of cell development GO:0010720 237 0.041
tube formation GO:0035148 140 0.041
regulation of dephosphorylation GO:0035303 18 0.041
rna localization GO:0006403 23 0.041
positive regulation of intracellular protein transport GO:0090316 42 0.041
lymphocyte homeostasis GO:0002260 64 0.041
retina homeostasis GO:0001895 23 0.040
response to follicle stimulating hormone GO:0032354 1 0.040
substrate dependent cell migration cell extension GO:0006930 4 0.040
negative regulation of protein localization to nucleus GO:1900181 23 0.039
mitochondrion organization GO:0007005 134 0.039
nuclear export GO:0051168 34 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
synapse assembly GO:0007416 56 0.039
muscle tissue development GO:0060537 308 0.039
mesoderm development GO:0007498 100 0.039
cation homeostasis GO:0055080 212 0.039
homotypic cell cell adhesion GO:0034109 28 0.038
positive regulation of secretion by cell GO:1903532 114 0.038
wound healing GO:0042060 157 0.038
negative regulation of neural precursor cell proliferation GO:2000178 18 0.038
protein heterooligomerization GO:0051291 14 0.038
regulation of hormone secretion GO:0046883 88 0.038
ensheathment of neurons GO:0007272 76 0.037
regulation of cell motility GO:2000145 236 0.037
epithelial tube formation GO:0072175 130 0.037
cellular response to calcium ion GO:0071277 14 0.037
regulation of ras protein signal transduction GO:0046578 114 0.037
positive regulation of actin filament depolymerization GO:0030836 5 0.037
regulation of embryonic development GO:0045995 71 0.037
purine nucleoside metabolic process GO:0042278 241 0.037
cellular response to peptide GO:1901653 92 0.037
negative regulation of cellular component organization GO:0051129 194 0.037
cell type specific apoptotic process GO:0097285 268 0.037
mitotic spindle organization GO:0007052 10 0.037
second messenger mediated signaling GO:0019932 73 0.036
cerebellar purkinje cell layer development GO:0021680 26 0.036
somatic stem cell division GO:0048103 19 0.036
neurotransmitter secretion GO:0007269 62 0.036
dendrite development GO:0016358 115 0.036
cellular metal ion homeostasis GO:0006875 151 0.035
response to acid chemical GO:0001101 111 0.035
ribonucleoside catabolic process GO:0042454 206 0.035
t cell activation GO:0042110 289 0.035
terminal button organization GO:0072553 3 0.035
regulation of peptide transport GO:0090087 91 0.035
hormone secretion GO:0046879 128 0.035
ribonucleoside monophosphate metabolic process GO:0009161 80 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.034
positive regulation of cellular component biogenesis GO:0044089 94 0.034
regulation of exocytosis GO:0017157 61 0.034
positive regulation of protein ubiquitination GO:0031398 27 0.034
purine nucleoside monophosphate metabolic process GO:0009126 81 0.034
negative regulation of intracellular transport GO:0032387 38 0.034
negative regulation of organelle organization GO:0010639 90 0.033
regulation of transmembrane transport GO:0034762 128 0.033
neural retina development GO:0003407 41 0.033
blood vessel morphogenesis GO:0048514 285 0.033
regulation of cysteine type endopeptidase activity GO:2000116 65 0.033
negative regulation of protein import into nucleus GO:0042308 21 0.033
purine nucleoside monophosphate catabolic process GO:0009128 58 0.033
protein k63 linked ubiquitination GO:0070534 6 0.033
transcription factor import into nucleus GO:0042991 26 0.032
action potential GO:0001508 78 0.032
myotube differentiation GO:0014902 105 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.032
cell growth GO:0016049 130 0.032
cellular response to metal ion GO:0071248 31 0.032
regulation of actin filament length GO:0030832 45 0.032
nucleoside phosphate biosynthetic process GO:1901293 79 0.032
regulation of dendritic spine morphogenesis GO:0061001 17 0.032
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.032
regulation of actin filament based process GO:0032970 99 0.031
carbohydrate catabolic process GO:0016052 32 0.031
ameboidal type cell migration GO:0001667 128 0.031
rho protein signal transduction GO:0007266 32 0.031
embryonic organ morphogenesis GO:0048562 276 0.031
cardiac chamber development GO:0003205 108 0.031
regulation of actin filament depolymerization GO:0030834 13 0.031
ribonucleoside metabolic process GO:0009119 245 0.030
retina morphogenesis in camera type eye GO:0060042 45 0.030
circadian behavior GO:0048512 13 0.030
positive regulation of peptidase activity GO:0010952 49 0.030
regulation of anatomical structure size GO:0090066 178 0.030
endoplasmic reticulum unfolded protein response GO:0030968 19 0.030
negative regulation of dephosphorylation GO:0035305 9 0.030
sequestering of calcium ion GO:0051208 18 0.030
rhythmic process GO:0048511 174 0.030
response to peptide hormone GO:0043434 127 0.030
cellular lipid metabolic process GO:0044255 323 0.029
positive regulation of secretion GO:0051047 130 0.029

Ppp2r1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.613
nervous system disease DOID:863 0 0.613
central nervous system disease DOID:331 0 0.113
sensory system disease DOID:0050155 0 0.105
epilepsy syndrome DOID:1826 0 0.047
brain disease DOID:936 0 0.047
electroclinical syndrome DOID:0050701 0 0.047
auditory system disease DOID:2742 0 0.043
nonsyndromic deafness DOID:0050563 0 0.043
neuromuscular disease DOID:440 0 0.031
charcot marie tooth disease DOID:10595 0 0.031
neuropathy DOID:870 0 0.031