Mus musculus

0 known processes

Ppp2r1b

protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform

(Aliases: 2410091N08Rik,AI790395)

Ppp2r1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
apoptotic signaling pathway GO:0097190 306 0.056
Human Mouse
positive regulation of apoptotic process GO:0043065 217 0.052
Human Mouse
negative regulation of protein metabolic process GO:0051248 282 0.049
cellular macromolecule catabolic process GO:0044265 206 0.047
dna metabolic process GO:0006259 303 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
regulation of membrane potential GO:0042391 192 0.043
macromolecule catabolic process GO:0009057 281 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
regulation of cell cycle GO:0051726 281 0.040
positive regulation of cell death GO:0010942 224 0.039
Human Mouse
protein ubiquitination GO:0016567 171 0.037
amine metabolic process GO:0009308 45 0.037
organonitrogen compound biosynthetic process GO:1901566 192 0.036
response to organonitrogen compound GO:0010243 246 0.035
oxidation reduction process GO:0055114 342 0.034
cation transport GO:0006812 399 0.034
cellular ketone metabolic process GO:0042180 84 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
cellular lipid metabolic process GO:0044255 323 0.032
transmembrane transport GO:0055085 412 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
cellular response to dna damage stimulus GO:0006974 207 0.031
regulation of hydrolase activity GO:0051336 246 0.031
protein catabolic process GO:0030163 221 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
negative regulation of protein modification process GO:0031400 163 0.029
male gamete generation GO:0048232 285 0.029
mrna metabolic process GO:0016071 84 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.028
Human Mouse
response to lipopolysaccharide GO:0032496 128 0.028
cell type specific apoptotic process GO:0097285 268 0.027
leukocyte differentiation GO:0002521 342 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
nitrogen compound transport GO:0071705 271 0.027
immune effector process GO:0002252 321 0.027
regulation of cell activation GO:0050865 289 0.027
cellular amine metabolic process GO:0044106 44 0.026
mitotic cell cycle process GO:1903047 159 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
ion transmembrane transport GO:0034220 361 0.026
cofactor metabolic process GO:0051186 80 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
spermatogenesis GO:0007283 284 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
negative regulation of cell cycle GO:0045786 123 0.024
cellular homeostasis GO:0019725 240 0.023
negative regulation of molecular function GO:0044092 258 0.023
regulation of defense response GO:0031347 233 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
positive regulation of programmed cell death GO:0043068 218 0.022
Human Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.022
regulation of transferase activity GO:0051338 263 0.022
regulation of kinase activity GO:0043549 249 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
cellular response to lipid GO:0071396 145 0.022
inorganic cation transmembrane transport GO:0098662 207 0.021
cellular chemical homeostasis GO:0055082 215 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
cytoplasmic transport GO:0016482 234 0.021
response to radiation GO:0009314 165 0.021
regulation of protein kinase activity GO:0045859 232 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
Human Mouse
negative regulation of immune system process GO:0002683 209 0.021
negative regulation of protein phosphorylation GO:0001933 126 0.021
b cell activation GO:0042113 161 0.020
cellular protein catabolic process GO:0044257 155 0.020
myeloid cell differentiation GO:0030099 233 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
cation transmembrane transport GO:0098655 266 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
carbohydrate metabolic process GO:0005975 230 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
cytokine production GO:0001816 319 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
negative regulation of transferase activity GO:0051348 85 0.020
regulation of hormone levels GO:0010817 211 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
regulation of proteolysis GO:0030162 164 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
ras protein signal transduction GO:0007265 77 0.019
protein maturation GO:0051604 176 0.019
rhythmic process GO:0048511 174 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
regulation of innate immune response GO:0045088 91 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
gonad development GO:0008406 141 0.019
dephosphorylation GO:0016311 129 0.019
Mouse
regulation of lymphocyte activation GO:0051249 240 0.019
negative regulation of cellular component organization GO:0051129 194 0.018
response to light stimulus GO:0009416 135 0.018
multicellular organismal signaling GO:0035637 91 0.018
skeletal system development GO:0001501 356 0.018
heterocycle catabolic process GO:0046700 280 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
sensory perception GO:0007600 245 0.018
t cell activation GO:0042110 289 0.018
negative regulation of cell cycle process GO:0010948 69 0.017
action potential GO:0001508 78 0.017
blood vessel morphogenesis GO:0048514 285 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
regulation of inflammatory response GO:0050727 147 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
membrane organization GO:0061024 245 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
organelle fission GO:0048285 170 0.017
carbohydrate homeostasis GO:0033500 128 0.017
locomotory behavior GO:0007626 195 0.017
rna processing GO:0006396 105 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
regulation of neuron differentiation GO:0045664 281 0.017
leukocyte proliferation GO:0070661 172 0.017
regulation of organelle organization GO:0033043 289 0.017
mitotic cell cycle GO:0000278 195 0.017
chromatin organization GO:0006325 206 0.017
regulation of protein localization GO:0032880 231 0.017
negative regulation of kinase activity GO:0033673 81 0.017
regulation of intracellular transport GO:0032386 159 0.017
organic anion transport GO:0015711 137 0.017
lymphocyte proliferation GO:0046651 164 0.016
fat cell differentiation GO:0045444 160 0.016
meiotic nuclear division GO:0007126 115 0.016
response to peptide GO:1901652 136 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
stem cell differentiation GO:0048863 268 0.016
camera type eye development GO:0043010 266 0.016
microtubule based process GO:0007017 236 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of cell cycle process GO:0010564 160 0.016
forebrain development GO:0030900 302 0.016
ossification GO:0001503 216 0.016
meiotic cell cycle GO:0051321 122 0.016
response to extracellular stimulus GO:0009991 127 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
coenzyme metabolic process GO:0006732 52 0.015
gene silencing GO:0016458 38 0.015
dna repair GO:0006281 107 0.015
regulation of peptidase activity GO:0052547 96 0.015
cell adhesion GO:0007155 329 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
divalent metal ion transport GO:0070838 172 0.015
regulation of response to wounding GO:1903034 189 0.015
asymmetric stem cell division GO:0098722 3 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of cytokine production GO:0001817 266 0.014
respiratory system development GO:0060541 190 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
response to nutrient levels GO:0031667 109 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
innate immune response GO:0045087 157 0.014
response to peptide hormone GO:0043434 127 0.014
regulation of secretion by cell GO:1903530 249 0.014
nucleotide metabolic process GO:0009117 332 0.014
circulatory system process GO:0003013 197 0.014
angiogenesis GO:0001525 201 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
positive regulation of cytokine production GO:0001819 174 0.014
peptide transport GO:0015833 133 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
regulation of cellular response to stress GO:0080135 159 0.014
anion transport GO:0006820 177 0.014
cell activation involved in immune response GO:0002263 126 0.014
response to insulin GO:0032868 100 0.014
striated muscle tissue development GO:0014706 293 0.014
regulation of mapk cascade GO:0043408 248 0.014
lymphocyte differentiation GO:0030098 242 0.014
glucose homeostasis GO:0042593 128 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
muscle tissue development GO:0060537 308 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
regulation of protein catabolic process GO:0042176 108 0.014
histone modification GO:0016570 159 0.014
glycerolipid metabolic process GO:0046486 122 0.013
lipid biosynthetic process GO:0008610 179 0.013
cellular response to peptide GO:1901653 92 0.013
regulation of homeostatic process GO:0032844 182 0.013
stem cell development GO:0048864 219 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
digestive system development GO:0055123 200 0.013
response to organic cyclic compound GO:0014070 198 0.013
inflammatory response GO:0006954 244 0.013
response to growth factor GO:0070848 198 0.013
positive regulation of cell development GO:0010720 237 0.013
actin cytoskeleton organization GO:0030036 220 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
fatty acid metabolic process GO:0006631 121 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
neural tube development GO:0021915 160 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
aromatic compound catabolic process GO:0019439 286 0.013
chromatin modification GO:0016568 187 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
transmission of nerve impulse GO:0019226 76 0.013
development of primary sexual characteristics GO:0045137 143 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
divalent inorganic cation transport GO:0072511 178 0.013
endocytosis GO:0006897 168 0.013
positive regulation of protein modification process GO:0031401 299 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
mitochondrion organization GO:0007005 134 0.013
response to oxidative stress GO:0006979 123 0.012
respiratory tube development GO:0030323 167 0.012
purine containing compound metabolic process GO:0072521 311 0.012
regulation of cell migration GO:0030334 219 0.012
organic acid biosynthetic process GO:0016053 86 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
blood circulation GO:0008015 195 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of cell projection organization GO:0031344 206 0.012
regulation of secretion GO:0051046 274 0.012
cellular amino acid biosynthetic process GO:0008652 22 0.012
regulation of translation GO:0006417 71 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
small molecule biosynthetic process GO:0044283 132 0.012
skin development GO:0043588 220 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
mapk cascade GO:0000165 281 0.012
nucleoside metabolic process GO:0009116 246 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
cell fate commitment GO:0045165 210 0.012
homeostasis of number of cells GO:0048872 210 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
chemotaxis GO:0006935 247 0.012
positive regulation of immune effector process GO:0002699 107 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
nuclear transport GO:0051169 139 0.012
neuron death GO:0070997 154 0.012
endomembrane system organization GO:0010256 147 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
lymphocyte apoptotic process GO:0070227 54 0.012
positive regulation of proteolysis GO:0045862 85 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
cell maturation GO:0048469 127 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
calcium ion transport GO:0006816 159 0.012
peptidyl amino acid modification GO:0018193 336 0.012
positive regulation of peptidase activity GO:0010952 49 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
Human Mouse
neuron apoptotic process GO:0051402 142 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
germ cell development GO:0007281 185 0.012
organonitrogen compound catabolic process GO:1901565 264 0.011
organism emergence from protective structure GO:0071684 4 0.011
skeletal muscle organ development GO:0060538 163 0.011
metal ion homeostasis GO:0055065 189 0.011
t cell proliferation GO:0042098 120 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
mrna processing GO:0006397 63 0.011
peptide hormone secretion GO:0030072 109 0.011
compound eye development GO:0048749 1 0.011
sensory organ morphogenesis GO:0090596 242 0.011
rna interference GO:0016246 2 0.011
neural tube formation GO:0001841 108 0.011
sequestering of calcium ion GO:0051208 18 0.011
positive regulation of defense response GO:0031349 124 0.011
cell cycle checkpoint GO:0000075 47 0.011
epithelial tube formation GO:0072175 130 0.011
cation homeostasis GO:0055080 212 0.011
dendrite development GO:0016358 115 0.011
response to inorganic substance GO:0010035 96 0.011
developmental maturation GO:0021700 193 0.011
defense response to other organism GO:0098542 197 0.011
wound healing GO:0042060 157 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.011
organelle localization GO:0051640 179 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
skeletal system morphogenesis GO:0048705 203 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
muscle cell differentiation GO:0042692 261 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
multicellular organism growth GO:0035264 161 0.011
sensory perception of sound GO:0007605 97 0.011
protein localization to organelle GO:0033365 185 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
sulfur compound metabolic process GO:0006790 100 0.011
leukocyte apoptotic process GO:0071887 71 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
regulation of protein transport GO:0051223 163 0.010
stem cell proliferation GO:0072089 117 0.010
monosaccharide metabolic process GO:0005996 106 0.010
tube formation GO:0035148 140 0.010
circadian rhythm GO:0007623 114 0.010
regulation of ossification GO:0030278 112 0.010
negative regulation of cell activation GO:0050866 111 0.010
protein processing GO:0016485 163 0.010
positive regulation of innate immune response GO:0045089 80 0.010
lung development GO:0030324 164 0.010
epidermis development GO:0008544 187 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
sequestering of metal ion GO:0051238 19 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
calcium ion homeostasis GO:0055074 127 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
translation GO:0006412 93 0.010
maintenance of location GO:0051235 89 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
asymmetric neuroblast division GO:0055059 1 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.010
protein localization to membrane GO:0072657 108 0.010
cellular ion homeostasis GO:0006873 165 0.010
response to uv GO:0009411 44 0.010
neural precursor cell proliferation GO:0061351 121 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010

Ppp2r1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
central nervous system disease DOID:331 0 0.018
disease of metabolism DOID:0014667 0 0.014