Mus musculus

63 known processes

Zfx

zinc finger protein X-linked

(Aliases: Zfx5,Zfx6,Zfx5,6)

Zfx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone modification GO:0016570 159 0.210
protein modification by small protein conjugation GO:0032446 187 0.176
cellular response to dna damage stimulus GO:0006974 207 0.171
regulation of cell cycle GO:0051726 281 0.156
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.140
hematopoietic progenitor cell differentiation GO:0002244 143 0.138
axon target recognition GO:0007412 4 0.127
chromatin modification GO:0016568 187 0.126
dna metabolic process GO:0006259 303 0.109
negative regulation of cellular amine metabolic process GO:0033239 1 0.105
apoptotic signaling pathway GO:0097190 306 0.105
modification dependent protein catabolic process GO:0019941 133 0.102
cellular amine metabolic process GO:0044106 44 0.102
protein ubiquitination GO:0016567 171 0.097
myeloid cell differentiation GO:0030099 233 0.096
negative regulation of transferase activity GO:0051348 85 0.094
peptidyl amino acid modification GO:0018193 336 0.087
regulation of apoptotic signaling pathway GO:2001233 197 0.085
regulation of cellular amino acid metabolic process GO:0006521 5 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.082
cajal body organization GO:0030576 1 0.078
regulation of neuron differentiation GO:0045664 281 0.072
rhythmic process GO:0048511 174 0.070
microtubule based process GO:0007017 236 0.070
male gamete generation GO:0048232 285 0.065
gland development GO:0048732 330 0.064
negative regulation of protein metabolic process GO:0051248 282 0.059
negative regulation of cellular protein metabolic process GO:0032269 247 0.057
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.055
multicellular organism growth GO:0035264 161 0.055
myeloid cell homeostasis GO:0002262 114 0.055
leukocyte differentiation GO:0002521 342 0.054
amine metabolic process GO:0009308 45 0.054
negative regulation of myeloid cell differentiation GO:0045638 38 0.053
cellular ketone metabolic process GO:0042180 84 0.052
regulation of cellular component biogenesis GO:0044087 181 0.051
natural killer cell activation GO:0030101 44 0.051
negative regulation of phosphorus metabolic process GO:0010563 184 0.051
neural tube development GO:0021915 160 0.050
chromatin organization GO:0006325 206 0.049
female gamete generation GO:0007292 74 0.048
dna packaging GO:0006323 30 0.047
digestive system development GO:0055123 200 0.045
negative regulation of immune system process GO:0002683 209 0.044
negative regulation of cell cycle GO:0045786 123 0.043
ossification GO:0001503 216 0.043
cytokine production GO:0001816 319 0.043
covalent chromatin modification GO:0016569 163 0.042
protein modification by small protein conjugation or removal GO:0070647 207 0.042
spermatogenesis GO:0007283 284 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
blastocyst development GO:0001824 80 0.039
megakaryocyte differentiation GO:0030219 26 0.039
male sex differentiation GO:0046661 109 0.039
regulation of cytokine production GO:0001817 266 0.038
regulation of chromosome organization GO:0033044 83 0.037
erythrocyte differentiation GO:0030218 88 0.036
positive regulation of cell development GO:0010720 237 0.035
regulation of chromatin modification GO:1903308 57 0.035
cell fate commitment GO:0045165 210 0.034
fat cell differentiation GO:0045444 160 0.034
regulation of lymphocyte activation GO:0051249 240 0.034
epithelial cell development GO:0002064 159 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.033
mitotic chromosome condensation GO:0007076 1 0.033
signal transduction by p53 class mediator GO:0072331 51 0.032
spermatid development GO:0007286 108 0.032
meiotic cell cycle process GO:1903046 77 0.032
cellular amino acid metabolic process GO:0006520 103 0.031
response to lipopolysaccharide GO:0032496 128 0.031
negative regulation of protein modification process GO:0031400 163 0.031
negative regulation of apoptotic signaling pathway GO:2001234 104 0.031
skeletal system development GO:0001501 356 0.031
oocyte construction GO:0007308 2 0.030
sensory organ morphogenesis GO:0090596 242 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
respiratory system development GO:0060541 190 0.030
t cell activation GO:0042110 289 0.030
modification dependent macromolecule catabolic process GO:0043632 133 0.030
negative regulation of molecular function GO:0044092 258 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
camera type eye development GO:0043010 266 0.029
circulatory system process GO:0003013 197 0.028
regulation of cell activation GO:0050865 289 0.028
regulation of t cell activation GO:0050863 170 0.028
muscle cell differentiation GO:0042692 261 0.028
response to molecule of bacterial origin GO:0002237 143 0.027
negative regulation of mitotic cell cycle GO:0045930 58 0.027
male gonad development GO:0008584 88 0.026
embryonic placenta development GO:0001892 98 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
meiotic nuclear division GO:0007126 115 0.026
cellular protein catabolic process GO:0044257 155 0.026
development of primary male sexual characteristics GO:0046546 88 0.026
positive regulation of apoptotic signaling pathway GO:2001235 95 0.026
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.026
regulation of mitotic cell cycle phase transition GO:1901990 73 0.026
meiosis i GO:0007127 60 0.026
stem cell differentiation GO:0048863 268 0.026
leukocyte proliferation GO:0070661 172 0.025
regulation of system process GO:0044057 200 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
positive regulation of nervous system development GO:0051962 221 0.025
morphogenesis of a branching epithelium GO:0061138 193 0.024
morphogenesis of a branching structure GO:0001763 203 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
epithelial cell proliferation GO:0050673 174 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
placenta development GO:0001890 140 0.024
germ cell development GO:0007281 185 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
chromosome segregation GO:0007059 48 0.023
regulation of cell cycle process GO:0010564 160 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
microtubule nucleation GO:0007020 2 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
compound eye development GO:0048749 1 0.022
positive regulation of protein modification process GO:0031401 299 0.022
natural killer cell differentiation GO:0001779 21 0.022
mrna processing GO:0006397 63 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
dendrite development GO:0016358 115 0.022
endocytosis GO:0006897 168 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
digestive tract development GO:0048565 190 0.021
regulation of protein complex assembly GO:0043254 83 0.021
mrna metabolic process GO:0016071 84 0.021
positive regulation of cell death GO:0010942 224 0.021
phagocytosis GO:0006909 66 0.021
neuron projection guidance GO:0097485 141 0.020
regulation of defense response GO:0031347 233 0.020
lateral inhibition GO:0046331 1 0.020
respiratory tube development GO:0030323 167 0.020
microtubule polymerization or depolymerization GO:0031109 26 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
peptidyl lysine modification GO:0018205 77 0.020
regulation of inflammatory response GO:0050727 147 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
microtubule organizing center organization GO:0031023 28 0.020
response to organonitrogen compound GO:0010243 246 0.019
negative regulation of nervous system development GO:0051961 156 0.019
positive regulation of transferase activity GO:0051347 167 0.019
rna interference GO:0016246 2 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
nuclear division GO:0000280 158 0.019
canonical wnt signaling pathway GO:0060070 130 0.018
retina development in camera type eye GO:0060041 119 0.018
regulation of cell cycle phase transition GO:1901987 77 0.018
regulation of actin cytoskeleton organization GO:0032956 84 0.018
maintenance of location GO:0051235 89 0.018
positive regulation of cell cycle process GO:0090068 61 0.018
chromatin assembly or disassembly GO:0006333 16 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
regulation of neuron death GO:1901214 134 0.018
cellular response to biotic stimulus GO:0071216 92 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
nitrogen compound transport GO:0071705 271 0.018
b cell differentiation GO:0030183 78 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
heart contraction GO:0060047 93 0.017
protein acylation GO:0043543 64 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
homeostasis of number of cells GO:0048872 210 0.017
response to peptide GO:1901652 136 0.017
chromatin remodeling at centromere GO:0031055 2 0.017
regulation of secretion GO:0051046 274 0.017
chemotaxis GO:0006935 247 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
regulation of organelle organization GO:0033043 289 0.017
inflammatory response GO:0006954 244 0.016
oocyte axis specification GO:0007309 2 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
protein polyubiquitination GO:0000209 33 0.016
spindle assembly involved in female meiosis i GO:0007057 2 0.016
regulation of neuron apoptotic process GO:0043523 122 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
dna templated transcription termination GO:0006353 4 0.016
innate immune response GO:0045087 157 0.016
activation of immune response GO:0002253 138 0.016
bone development GO:0060348 120 0.016
protein dna complex subunit organization GO:0071824 28 0.016
positive regulation of cytokine production GO:0001819 174 0.016
response to radiation GO:0009314 165 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
regulation of protein kinase activity GO:0045859 232 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
regulation of response to wounding GO:1903034 189 0.015
cellular lipid metabolic process GO:0044255 323 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
spindle assembly involved in meiosis GO:0090306 4 0.015
wound healing GO:0042060 157 0.015
definitive hemopoiesis GO:0060216 20 0.015
leukocyte tethering or rolling GO:0050901 3 0.015
regulation of transforming growth factor beta2 production GO:0032909 2 0.015
cellular protein complex assembly GO:0043623 116 0.015
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.015
cellular response to lipid GO:0071396 145 0.015
regulation of osteoblast differentiation GO:0045667 67 0.015
protein methylation GO:0006479 81 0.015
establishment of meiotic spindle orientation GO:0051296 1 0.015
cellular response to hormone stimulus GO:0032870 150 0.014
cellularization GO:0007349 1 0.014
b cell activation GO:0042113 161 0.014
macromolecule catabolic process GO:0009057 281 0.014
wnt signaling pathway GO:0016055 188 0.014
mitotic cell cycle process GO:1903047 159 0.014
retina morphogenesis in camera type eye GO:0060042 45 0.014
mitotic nuclear division GO:0007067 48 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
circadian rhythm GO:0007623 114 0.014
protein secretion GO:0009306 111 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
cell substrate adhesion GO:0031589 130 0.014
regulation of cell projection organization GO:0031344 206 0.014
developmental maturation GO:0021700 193 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
regulation of protein ubiquitination GO:0031396 52 0.013
gonad development GO:0008406 141 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
negative regulation of cell activation GO:0050866 111 0.013
stem cell development GO:0048864 219 0.013
cell division GO:0051301 120 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
g1 s transition of mitotic cell cycle GO:0000082 57 0.013
spermatid differentiation GO:0048515 115 0.013
lung development GO:0030324 164 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
skin development GO:0043588 220 0.013
protein catabolic process GO:0030163 221 0.013
blood circulation GO:0008015 195 0.013
regulation of neuron projection development GO:0010975 169 0.013
positive regulation of ossification GO:0045778 47 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.013
regulation of neural precursor cell proliferation GO:2000177 70 0.013
protein polymerization GO:0051258 57 0.013
regulation of hepatocyte proliferation GO:2000345 6 0.013
positive regulation of t cell activation GO:0050870 101 0.012
regulation of ossification GO:0030278 112 0.012
centrosome separation GO:0051299 4 0.012
muscle tissue development GO:0060537 308 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
centrosome organization GO:0051297 26 0.012
mitotic sister chromatid segregation GO:0000070 14 0.012
cell growth GO:0016049 130 0.012
histone acetylation GO:0016573 41 0.012
hindbrain development GO:0030902 128 0.012
defecation GO:0030421 1 0.012
b cell proliferation GO:0042100 53 0.012
response to acid chemical GO:0001101 111 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.011
cell matrix adhesion GO:0007160 68 0.011
response to insulin GO:0032868 100 0.011
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.011
regulation of synapse structural plasticity GO:0051823 4 0.011
cellular response to interferon gamma GO:0071346 25 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
microtubule polymerization GO:0046785 12 0.011
regulation of chromatin organization GO:1902275 57 0.011
response to peptide hormone GO:0043434 127 0.011
negative regulation of fat cell differentiation GO:0045599 36 0.011
urogenital system development GO:0001655 261 0.011
positive regulation of defense response GO:0031349 124 0.011
gene silencing by rna GO:0031047 19 0.011
regulation of kinase activity GO:0043549 249 0.011
lymphocyte proliferation GO:0046651 164 0.011
internal peptidyl lysine acetylation GO:0018393 42 0.011
aromatic compound catabolic process GO:0019439 286 0.011
maintenance of protein location in nucleus GO:0051457 2 0.011
chromatin assembly GO:0031497 13 0.011
limb development GO:0060173 166 0.011
cytokine mediated signaling pathway GO:0019221 115 0.010
t cell differentiation GO:0030217 174 0.010
positive regulation of cell cycle GO:0045787 92 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
sertoli cell development GO:0060009 15 0.010
dna recombination GO:0006310 92 0.010
regulation of protein secretion GO:0050708 82 0.010
nucleotide metabolic process GO:0009117 332 0.010
negative regulation of response to wounding GO:1903035 77 0.010
regulation of mapk cascade GO:0043408 248 0.010
positive regulation of cell activation GO:0050867 158 0.010

Zfx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.127
nervous system disease DOID:863 0 0.127
sensory system disease DOID:0050155 0 0.059
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
central nervous system disease DOID:331 0 0.023
neurodegenerative disease DOID:1289 0 0.023
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
reproductive system disease DOID:15 0 0.010