Mus musculus

16 known processes

Ube2e3

ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog (yeast)

(Aliases: Ubce4,ubcM2)

Ube2e3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein ubiquitination GO:0016567 171 0.231
oocyte axis specification GO:0007309 2 0.171
ubiquitin dependent protein catabolic process GO:0006511 129 0.153
protein modification by small protein conjugation GO:0032446 187 0.123
cellular macromolecule catabolic process GO:0044265 206 0.122
oocyte construction GO:0007308 2 0.110
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.082
pole plasm assembly GO:0007315 2 0.082
male gamete generation GO:0048232 285 0.081
modification dependent protein catabolic process GO:0019941 133 0.077
macromolecule catabolic process GO:0009057 281 0.077
regulation of transferase activity GO:0051338 263 0.076
germ cell development GO:0007281 185 0.075
spermatogenesis GO:0007283 284 0.070
cellular protein catabolic process GO:0044257 155 0.069
cellular amine metabolic process GO:0044106 44 0.069
cellular amino acid metabolic process GO:0006520 103 0.067
protein catabolic process GO:0030163 221 0.067
regulation of protein kinase activity GO:0045859 232 0.063
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.062
regulation of cellular amino acid metabolic process GO:0006521 5 0.061
placenta development GO:0001890 140 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
amine metabolic process GO:0009308 45 0.056
translation GO:0006412 93 0.055
olfactory learning GO:0008355 2 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.048
golgi localization GO:0051645 4 0.048
intracellular mrna localization GO:0008298 4 0.048
apoptotic signaling pathway GO:0097190 306 0.048
protein modification by small protein conjugation or removal GO:0070647 207 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
proteasomal protein catabolic process GO:0010498 98 0.045
small gtpase mediated signal transduction GO:0007264 97 0.044
cell division GO:0051301 120 0.044
positive regulation of protein modification process GO:0031401 299 0.044
mrna metabolic process GO:0016071 84 0.042
maternal determination of anterior posterior axis embryo GO:0008358 2 0.042
mitotic cell cycle GO:0000278 195 0.041
cellular response to dna damage stimulus GO:0006974 207 0.037
dna metabolic process GO:0006259 303 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
cellular ketone metabolic process GO:0042180 84 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.037
regulation of kinase activity GO:0043549 249 0.036
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.036
regulation of cell activation GO:0050865 289 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
chromatin organization GO:0006325 206 0.034
wnt signaling pathway GO:0016055 188 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
glycosyl compound metabolic process GO:1901657 246 0.033
regulation of organelle organization GO:0033043 289 0.033
t cell activation GO:0042110 289 0.032
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.032
peptidyl amino acid modification GO:0018193 336 0.032
spermatid development GO:0007286 108 0.031
organelle fission GO:0048285 170 0.031
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
compound eye development GO:0048749 1 0.031
oocyte anterior posterior axis specification GO:0007314 2 0.030
negative regulation of immune system process GO:0002683 209 0.030
meiosis i GO:0007127 60 0.029
organelle localization GO:0051640 179 0.029
regionalization GO:0003002 337 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
stem cell development GO:0048864 219 0.029
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.028
regulation of cell cycle GO:0051726 281 0.028
rna splicing via transesterification reactions GO:0000375 43 0.028
glycosyl compound catabolic process GO:1901658 206 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
cell fate commitment GO:0045165 210 0.028
mrna splicing via spliceosome GO:0000398 43 0.028
myeloid cell differentiation GO:0030099 233 0.028
microtubule cytoskeleton organization GO:0000226 157 0.027
rna splicing GO:0008380 54 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
b cell activation GO:0042113 161 0.027
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.027
homeostasis of number of cells GO:0048872 210 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
multicellular organism growth GO:0035264 161 0.026
rna processing GO:0006396 105 0.025
lymphocyte mediated immunity GO:0002449 139 0.024
posttranscriptional gene silencing GO:0016441 10 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.023
cell adhesion GO:0007155 329 0.023
mitotic cell cycle process GO:1903047 159 0.023
mrna processing GO:0006397 63 0.023
developmental maturation GO:0021700 193 0.023
organophosphate catabolic process GO:0046434 232 0.023
mitotic chromosome condensation GO:0007076 1 0.023
positive regulation of cell development GO:0010720 237 0.023
leukocyte differentiation GO:0002521 342 0.022
aromatic compound catabolic process GO:0019439 286 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.022
gene silencing GO:0016458 38 0.022
nucleotide catabolic process GO:0009166 217 0.021
oocyte differentiation GO:0009994 35 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
fat cell differentiation GO:0045444 160 0.021
nuclear division GO:0000280 158 0.021
purine containing compound catabolic process GO:0072523 213 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
negative regulation of lymphocyte activation GO:0051250 91 0.020
positive regulation of cell cycle GO:0045787 92 0.020
male meiosis i GO:0007141 16 0.020
regulation of response to wounding GO:1903034 189 0.020
cytoplasmic transport GO:0016482 234 0.020
negative regulation of t cell activation GO:0050868 65 0.020
cell maturation GO:0048469 127 0.020
rna interference GO:0016246 2 0.020
transmembrane transport GO:0055085 412 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
response to light stimulus GO:0009416 135 0.019
establishment of organelle localization GO:0051656 122 0.019
organelle assembly GO:0070925 177 0.019
regulation of translation GO:0006417 71 0.019
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.019
meiotic cell cycle GO:0051321 122 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
male anatomical structure morphogenesis GO:0090598 4 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
synaptic transmission GO:0007268 329 0.018
leukocyte proliferation GO:0070661 172 0.018
response to radiation GO:0009314 165 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
lateral inhibition GO:0046331 1 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
oogenesis GO:0048477 56 0.018
microtubule based process GO:0007017 236 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
response to uv GO:0009411 44 0.018
negative regulation of cell activation GO:0050866 111 0.018
negative regulation of molecular function GO:0044092 258 0.017
epidermis development GO:0008544 187 0.017
regulation of t cell activation GO:0050863 170 0.017
stem cell maintenance GO:0019827 130 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
spermatid differentiation GO:0048515 115 0.017
ribonucleoprotein complex subunit organization GO:0071826 28 0.017
nucleotide metabolic process GO:0009117 332 0.017
negative regulation of protein modification process GO:0031400 163 0.017
regulation of myeloid cell differentiation GO:0045637 96 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.017
nucleoside catabolic process GO:0009164 206 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of proteolysis GO:0030162 164 0.016
autophagy GO:0006914 45 0.016
myeloid cell homeostasis GO:0002262 114 0.016
t cell proliferation GO:0042098 120 0.016
regulation of protein catabolic process GO:0042176 108 0.016
negative regulation of cell cycle GO:0045786 123 0.016
histone modification GO:0016570 159 0.016
regulation of membrane potential GO:0042391 192 0.016
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.016
regulation of secretion GO:0051046 274 0.016
response to lipopolysaccharide GO:0032496 128 0.016
oocyte development GO:0048599 33 0.016
dna recombination GO:0006310 92 0.016
tube formation GO:0035148 140 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
exocytosis GO:0006887 121 0.015
asymmetric stem cell division GO:0098722 3 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
cellular lipid metabolic process GO:0044255 323 0.015
stem cell proliferation GO:0072089 117 0.015
rhythmic process GO:0048511 174 0.015
blood vessel morphogenesis GO:0048514 285 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
locomotory behavior GO:0007626 195 0.015
nitrogen compound transport GO:0071705 271 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
positive regulation of cell death GO:0010942 224 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
epithelial cell proliferation GO:0050673 174 0.014
development of primary sexual characteristics GO:0045137 143 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
meiotic cell cycle process GO:1903046 77 0.014
negative regulation of transferase activity GO:0051348 85 0.014
regulation of microtubule based process GO:0032886 52 0.014
localization within membrane GO:0051668 4 0.014
regulation of cell division GO:0051302 76 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of circadian rhythm GO:0042752 58 0.014
immunoglobulin mediated immune response GO:0016064 69 0.014
positive regulation of dna templated transcription elongation GO:0032786 2 0.013
cell type specific apoptotic process GO:0097285 268 0.013
gland development GO:0048732 330 0.013
asymmetric neuroblast division GO:0055059 1 0.013
copii coated vesicle budding GO:0090114 2 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
nucleoside metabolic process GO:0009116 246 0.013
respiratory system development GO:0060541 190 0.013
positive regulation of nervous system development GO:0051962 221 0.013
protein methylation GO:0006479 81 0.013
circadian rhythm GO:0007623 114 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
female gamete generation GO:0007292 74 0.013
multi multicellular organism process GO:0044706 109 0.013
lymphocyte differentiation GO:0030098 242 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of autophagy GO:0010506 30 0.013
regulation of cellular response to stress GO:0080135 159 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
skeletal system development GO:0001501 356 0.013
regulation of cell projection organization GO:0031344 206 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
sensory perception GO:0007600 245 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
regulation of b cell proliferation GO:0030888 39 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.012
ras protein signal transduction GO:0007265 77 0.012
negative regulation of cell development GO:0010721 169 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
immunoglobulin production GO:0002377 73 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
regulation of hormone levels GO:0010817 211 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
ion transmembrane transport GO:0034220 361 0.012
chromosome segregation GO:0007059 48 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
neural precursor cell proliferation GO:0061351 121 0.012
cellular chemical homeostasis GO:0055082 215 0.012
glucose homeostasis GO:0042593 128 0.012
mitotic nuclear division GO:0007067 48 0.012
cellular homeostasis GO:0019725 240 0.011
skin development GO:0043588 220 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
inflammatory response GO:0006954 244 0.011
positive regulation of organelle organization GO:0010638 128 0.011
dna conformation change GO:0071103 37 0.011
protein polymerization GO:0051258 57 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
ameboidal type cell migration GO:0001667 128 0.011
protein maturation GO:0051604 176 0.011
learning or memory GO:0007611 148 0.011
regulation of t cell proliferation GO:0042129 92 0.011
negative regulation of kinase activity GO:0033673 81 0.011
protein alkylation GO:0008213 81 0.011
axonogenesis GO:0007409 274 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
histone methylation GO:0016571 71 0.011
lipid biosynthetic process GO:0008610 179 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of intracellular transport GO:0032386 159 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of nuclear division GO:0051783 56 0.011
positive regulation of rna splicing GO:0033120 12 0.011
digestive tract development GO:0048565 190 0.011
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
segmentation GO:0035282 93 0.011
regulation of mrna processing GO:0050684 41 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
macromolecule methylation GO:0043414 120 0.011
positive regulation of mrna metabolic process GO:1903313 17 0.011
leukocyte mediated immunity GO:0002443 174 0.011
adaptive immune response GO:0002250 155 0.011
response to extracellular stimulus GO:0009991 127 0.011
protein localization to organelle GO:0033365 185 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
adult behavior GO:0030534 135 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
forebrain development GO:0030900 302 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.011
regulation of mapk cascade GO:0043408 248 0.011
regulation of inflammatory response GO:0050727 147 0.011
formation of organ boundary GO:0010160 1 0.010
cell cycle switching GO:0060184 1 0.010
chemotaxis GO:0006935 247 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
positive regulation of immune effector process GO:0002699 107 0.010
fertilization GO:0009566 127 0.010
endocytosis GO:0006897 168 0.010
response to organonitrogen compound GO:0010243 246 0.010
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.010
positive regulation of translation GO:0045727 19 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
cellular response to nutrient levels GO:0031669 64 0.010

Ube2e3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of mental health DOID:150 0 0.026
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.021
neurodegenerative disease DOID:1289 0 0.014