Mus musculus

0 known processes

Tlk2

tousled-like kinase 2 (Arabidopsis)

(Aliases: 4933403M19Rik,PKUalpha,Tlk)

Tlk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.083
cellular amino acid metabolic process GO:0006520 103 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.063
cellular amine metabolic process GO:0044106 44 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.059
modification dependent protein catabolic process GO:0019941 133 0.058
Human
protein modification by small protein conjugation or removal GO:0070647 207 0.057
regulation of chromosome organization GO:0033044 83 0.057
Human
amine metabolic process GO:0009308 45 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
protein modification by small protein conjugation GO:0032446 187 0.050
negative regulation of protein metabolic process GO:0051248 282 0.047
Human
peptidyl amino acid modification GO:0018193 336 0.044
Human
protein ubiquitination GO:0016567 171 0.040
regulation of organelle organization GO:0033043 289 0.038
Human
protein localization to organelle GO:0033365 185 0.036
ubiquitin dependent protein catabolic process GO:0006511 129 0.036
Human
histone modification GO:0016570 159 0.036
Fly
methylation GO:0032259 134 0.033
Worm
covalent chromatin modification GO:0016569 163 0.031
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
small gtpase mediated signal transduction GO:0007264 97 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.028
Human
purine containing compound metabolic process GO:0072521 311 0.027
response to radiation GO:0009314 165 0.027
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
Human
protein catabolic process GO:0030163 221 0.026
Human
regulation of cell cycle GO:0051726 281 0.025
Fly
cellular response to organonitrogen compound GO:0071417 145 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
mitotic cell cycle GO:0000278 195 0.025
Fly
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
regulation of hydrolase activity GO:0051336 246 0.025
ras protein signal transduction GO:0007265 77 0.025
regulation of protein localization GO:0032880 231 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
Human
negative regulation of molecular function GO:0044092 258 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.024
carbohydrate metabolic process GO:0005975 230 0.023
protein import GO:0017038 101 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
nucleotide metabolic process GO:0009117 332 0.022
chromatin organization GO:0006325 206 0.022
Human Fly
nucleoside phosphate metabolic process GO:0006753 338 0.022
purine containing compound catabolic process GO:0072523 213 0.021
homeostasis of number of cells GO:0048872 210 0.021
dna metabolic process GO:0006259 303 0.021
microtubule based process GO:0007017 236 0.020
positive regulation of protein modification process GO:0031401 299 0.019
Worm
aromatic compound catabolic process GO:0019439 286 0.019
nuclear division GO:0000280 158 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
spermatogenesis GO:0007283 284 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
development of primary sexual characteristics GO:0045137 143 0.018
cellular response to lipid GO:0071396 145 0.018
chromatin modification GO:0016568 187 0.018
Fly
regulation of protein catabolic process GO:0042176 108 0.018
Human
organelle fission GO:0048285 170 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of cell cycle process GO:0010564 160 0.018
response to organic cyclic compound GO:0014070 198 0.018
cytokine production GO:0001816 319 0.018
protein localization to nucleus GO:0034504 121 0.018
intracellular protein transport GO:0006886 204 0.018
negative regulation of protein modification process GO:0031400 163 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
dephosphorylation GO:0016311 129 0.017
regulation of cytokine production GO:0001817 266 0.017
nucleoside metabolic process GO:0009116 246 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
Human
macromolecule methylation GO:0043414 120 0.017
Worm
positive regulation of programmed cell death GO:0043068 218 0.017
positive regulation of glial cell proliferation GO:0060252 4 0.017
positive regulation of nervous system development GO:0051962 221 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
Human
cellular response to hormone stimulus GO:0032870 150 0.017
regulation of mapk cascade GO:0043408 248 0.017
nuclear import GO:0051170 95 0.017
mapk cascade GO:0000165 281 0.016
regulation of histone modification GO:0031056 56 0.016
negative regulation of nervous system development GO:0051961 156 0.016
neuronal action potential GO:0019228 54 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
macromolecule catabolic process GO:0009057 281 0.016
Human
positive regulation of cell death GO:0010942 224 0.016
transmembrane transport GO:0055085 412 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
muscle cell differentiation GO:0042692 261 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
cellular lipid metabolic process GO:0044255 323 0.015
immune effector process GO:0002252 321 0.015
cellular protein catabolic process GO:0044257 155 0.015
Human
organonitrogen compound catabolic process GO:1901565 264 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
Human
leukocyte differentiation GO:0002521 342 0.015
protein import into nucleus GO:0006606 95 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
cell division GO:0051301 120 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
regulation of protein transport GO:0051223 163 0.015
regulation of chromatin modification GO:1903308 57 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
regulation of chromatin organization GO:1902275 57 0.015
Human
nucleoside triphosphate metabolic process GO:0009141 230 0.015
cation transport GO:0006812 399 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
transmission of nerve impulse GO:0019226 76 0.014
regulation of proteolysis GO:0030162 164 0.014
Human
purine nucleotide metabolic process GO:0006163 302 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
ossification GO:0001503 216 0.014
cytoplasmic transport GO:0016482 234 0.014
fat cell differentiation GO:0045444 160 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
male gamete generation GO:0048232 285 0.014
regulation of hormone levels GO:0010817 211 0.014
skeletal system development GO:0001501 356 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
action potential GO:0001508 78 0.014
t cell activation GO:0042110 289 0.014
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of protein kinase activity GO:0045859 232 0.013
Worm
protein alkylation GO:0008213 81 0.013
Worm
organophosphate catabolic process GO:0046434 232 0.013
regulation of defense response GO:0031347 233 0.013
peptidyl lysine modification GO:0018205 77 0.013
rna processing GO:0006396 105 0.013
apoptotic signaling pathway GO:0097190 306 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
response to insulin GO:0032868 100 0.013
inflammatory response GO:0006954 244 0.013
cellular homeostasis GO:0019725 240 0.013
striated muscle tissue development GO:0014706 293 0.013
gland development GO:0048732 330 0.013
nucleotide catabolic process GO:0009166 217 0.013
negative regulation of organelle organization GO:0010639 90 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
regulation of kinase activity GO:0043549 249 0.013
Worm
muscle tissue development GO:0060537 308 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of membrane potential GO:0042391 192 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
Human
response to light stimulus GO:0009416 135 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
chromosome segregation GO:0007059 48 0.012
Human Fly
regulation of protein import into nucleus GO:0042306 52 0.012
protein targeting GO:0006605 143 0.012
regulation of protein complex assembly GO:0043254 83 0.012
regulation of intracellular transport GO:0032386 159 0.012
meiotic nuclear division GO:0007126 115 0.012
glucose metabolic process GO:0006006 92 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
Human
negative regulation of immune system process GO:0002683 209 0.012
heterocycle catabolic process GO:0046700 280 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
Human
single organism nuclear import GO:1902593 95 0.012
multicellular organism growth GO:0035264 161 0.012
Worm
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
protein maturation GO:0051604 176 0.012
Human
cytokine mediated signaling pathway GO:0019221 115 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
regulation of neuron differentiation GO:0045664 281 0.012
nuclear transport GO:0051169 139 0.012
stem cell differentiation GO:0048863 268 0.012
nitrogen compound transport GO:0071705 271 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
cellular protein complex assembly GO:0043623 116 0.011
maintenance of location GO:0051235 89 0.011
endocytosis GO:0006897 168 0.011
monosaccharide metabolic process GO:0005996 106 0.011
cilium assembly GO:0042384 81 0.011
gliogenesis GO:0042063 141 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
anatomical structure homeostasis GO:0060249 145 0.011
meiotic cell cycle GO:0051321 122 0.011
negative regulation of cell cycle GO:0045786 123 0.011
peptide transport GO:0015833 133 0.011
skeletal system morphogenesis GO:0048705 203 0.011
cognition GO:0050890 149 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
negative regulation of protein processing GO:0010955 79 0.011
Human
rna interference GO:0016246 2 0.011
negative regulation of cell development GO:0010721 169 0.011
intracellular mrna localization GO:0008298 4 0.011
regulation of protein stability GO:0031647 52 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
cation transmembrane transport GO:0098655 266 0.011
protein processing GO:0016485 163 0.011
Human
myeloid cell differentiation GO:0030099 233 0.011
dna repair GO:0006281 107 0.010
regulation of system process GO:0044057 200 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
sensory perception GO:0007600 245 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
Worm
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
lymphocyte differentiation GO:0030098 242 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
erk1 and erk2 cascade GO:0070371 77 0.010
regulation of homeostatic process GO:0032844 182 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
regulation of t cell activation GO:0050863 170 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010

Tlk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.015