Mus musculus

43 known processes

Agr2

anterior gradient 2 (Xenopus laevis)

(Aliases: XAG-2,Gob-4,HAG-2,Agr2h,mAG-2)

Agr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.153
cellular amino acid metabolic process GO:0006520 103 0.144
amine metabolic process GO:0009308 45 0.106
negative regulation of immune system process GO:0002683 209 0.098
cytokine production GO:0001816 319 0.098
organonitrogen compound biosynthetic process GO:1901566 192 0.094
regulation of cytokine production GO:0001817 266 0.094
peptidyl amino acid modification GO:0018193 336 0.077
regulation of cellular amine metabolic process GO:0033238 20 0.070
fertilization GO:0009566 127 0.069
carbohydrate derivative biosynthetic process GO:1901137 183 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
apoptotic signaling pathway GO:0097190 306 0.068
male gamete generation GO:0048232 285 0.061
cellular lipid metabolic process GO:0044255 323 0.060
lipid biosynthetic process GO:0008610 179 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.056
regulation of response to wounding GO:1903034 189 0.055
cellular ketone metabolic process GO:0042180 84 0.054
negative regulation of cell activation GO:0050866 111 0.051
activation of immune response GO:0002253 138 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
binding of sperm to zona pellucida GO:0007339 34 0.049
respiratory tube development GO:0030323 167 0.046
regulation of secretion GO:0051046 274 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
regulation of protein transport GO:0051223 163 0.046
regulation of establishment of protein localization GO:0070201 181 0.044
negative regulation of cell proliferation GO:0008285 296 0.042
purine containing compound metabolic process GO:0072521 311 0.042
immune effector process GO:0002252 321 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
protein processing GO:0016485 163 0.040
leukocyte differentiation GO:0002521 342 0.040
glycoprotein metabolic process GO:0009100 116 0.040
t cell activation GO:0042110 289 0.039
intrinsic apoptotic signaling pathway GO:0097193 132 0.039
regulation of cell migration GO:0030334 219 0.038
regulation of cell activation GO:0050865 289 0.037
defense response to bacterium GO:0042742 119 0.036
small gtpase mediated signal transduction GO:0007264 97 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
nucleotide metabolic process GO:0009117 332 0.035
regulation of t cell activation GO:0050863 170 0.034
lung development GO:0030324 164 0.034
immune response activating signal transduction GO:0002757 116 0.034
defense response to other organism GO:0098542 197 0.033
multicellular organismal homeostasis GO:0048871 164 0.033
lymphocyte differentiation GO:0030098 242 0.032
long chain fatty acid import GO:0044539 2 0.032
lymphocyte proliferation GO:0046651 164 0.032
spermatogenesis GO:0007283 284 0.032
epithelial cell development GO:0002064 159 0.032
regulation of lymphocyte activation GO:0051249 240 0.032
regulation of multi organism process GO:0043900 111 0.032
positive regulation of programmed cell death GO:0043068 218 0.031
blood circulation GO:0008015 195 0.031
alcohol metabolic process GO:0006066 116 0.031
regulation of secretion by cell GO:1903530 249 0.030
sperm egg recognition GO:0035036 37 0.030
immune response regulating signaling pathway GO:0002764 125 0.030
negative regulation of phosphorus metabolic process GO:0010563 184 0.030
regulation of cell motility GO:2000145 236 0.030
endocytosis GO:0006897 168 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.029
cation transport GO:0006812 399 0.029
positive regulation of secretion GO:0051047 130 0.029
striated muscle tissue development GO:0014706 293 0.029
regulation of defense response GO:0031347 233 0.029
protein secretion GO:0009306 111 0.028
regulation of lymphocyte differentiation GO:0045619 107 0.028
respiratory system development GO:0060541 190 0.028
small molecule biosynthetic process GO:0044283 132 0.028
response to organonitrogen compound GO:0010243 246 0.027
muscle cell differentiation GO:0042692 261 0.027
glycoprotein biosynthetic process GO:0009101 89 0.027
transmembrane transport GO:0055085 412 0.026
heterocycle catabolic process GO:0046700 280 0.026
negative regulation of secretion GO:0051048 61 0.026
purine containing compound catabolic process GO:0072523 213 0.026
cellular response to cytokine stimulus GO:0071345 189 0.026
single fertilization GO:0007338 82 0.026
nitrogen compound transport GO:0071705 271 0.025
organophosphate biosynthetic process GO:0090407 122 0.025
positive regulation of defense response GO:0031349 124 0.025
muscle tissue development GO:0060537 308 0.025
cation transmembrane transport GO:0098655 266 0.025
ossification GO:0001503 216 0.025
germ cell development GO:0007281 185 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
cell adhesion GO:0007155 329 0.025
peptide metabolic process GO:0006518 46 0.025
humoral immune response GO:0006959 57 0.025
regulation of cell cycle GO:0051726 281 0.024
heart morphogenesis GO:0003007 178 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
leukocyte activation involved in immune response GO:0002366 126 0.024
digestive system development GO:0055123 200 0.023
Zebrafish
lipid localization GO:0010876 126 0.023
cellular homeostasis GO:0019725 240 0.023
oxidation reduction process GO:0055114 342 0.023
t cell differentiation GO:0030217 174 0.023
gland development GO:0048732 330 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
response to inorganic substance GO:0010035 96 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.022
response to organic cyclic compound GO:0014070 198 0.022
short chain fatty acid catabolic process GO:0019626 2 0.022
skeletal muscle organ development GO:0060538 163 0.022
action potential GO:0001508 78 0.022
cell substrate adhesion GO:0031589 130 0.022
camera type eye development GO:0043010 266 0.022
antimicrobial peptide biosynthetic process GO:0002777 2 0.022
cellular response to lipid GO:0071396 145 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
aromatic compound catabolic process GO:0019439 286 0.022
regulation of mapk cascade GO:0043408 248 0.022
sulfate assimilation GO:0000103 3 0.022
positive regulation of cytokine production GO:0001819 174 0.022
skeletal system development GO:0001501 356 0.022
regulation of protein localization GO:0032880 231 0.021
protein glycosylation GO:0006486 55 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
macromolecule glycosylation GO:0043413 55 0.021
muscle system process GO:0003012 141 0.021
regulation of protein secretion GO:0050708 82 0.021
cell activation involved in immune response GO:0002263 126 0.021
regulation of cellular response to stress GO:0080135 159 0.021
prevention of polyspermy GO:0060468 4 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
glycerolipid metabolic process GO:0046486 122 0.021
cell cell recognition GO:0009988 44 0.021
regulation of transferase activity GO:0051338 263 0.021
epithelial cell proliferation GO:0050673 174 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
positive regulation of apoptotic process GO:0043065 217 0.020
organic acid biosynthetic process GO:0016053 86 0.020
response to acid chemical GO:0001101 111 0.020
dna metabolic process GO:0006259 303 0.020
fatty acid metabolic process GO:0006631 121 0.020
regulation of reproductive process GO:2000241 66 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
bone development GO:0060348 120 0.020
positive regulation of cell activation GO:0050867 158 0.019
response to lipopolysaccharide GO:0032496 128 0.019
positive regulation of epithelial cell proliferation GO:0050679 68 0.019
positive regulation of response to wounding GO:1903036 66 0.019
sterol homeostasis GO:0055092 45 0.019
regulation of anatomical structure size GO:0090066 178 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
cellular response to acid chemical GO:0071229 68 0.019
regulation of inflammatory response GO:0050727 147 0.019
compound eye development GO:0048749 1 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
isoprenoid metabolic process GO:0006720 29 0.019
regulation of cytokine secretion GO:0050707 61 0.019
negative regulation of protein modification process GO:0031400 163 0.019
cellular chemical homeostasis GO:0055082 215 0.018
myotube differentiation GO:0014902 105 0.018
extracellular structure organization GO:0043062 148 0.018
ion transmembrane transport GO:0034220 361 0.018
regulation of protein maturation GO:1903317 96 0.018
regulation of t cell differentiation GO:0045580 83 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
microtubule based process GO:0007017 236 0.018
protein maturation GO:0051604 176 0.018
regulation of binding GO:0051098 111 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
maintenance of location GO:0051235 89 0.018
regulation of protein processing GO:0070613 96 0.018
cytoplasmic transport GO:0016482 234 0.018
regulation of striated muscle cell differentiation GO:0051153 81 0.018
innate immune response GO:0045087 157 0.017
macromolecule catabolic process GO:0009057 281 0.017
glycosylation GO:0070085 62 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
regulation of intracellular transport GO:0032386 159 0.017
mapk cascade GO:0000165 281 0.017
regulation of membrane potential GO:0042391 192 0.017
positive regulation of protein modification process GO:0031401 299 0.017
protein localization to membrane GO:0072657 108 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
cytokine biosynthetic process GO:0042089 68 0.017
sulfur compound metabolic process GO:0006790 100 0.017
transmission of nerve impulse GO:0019226 76 0.017
positive regulation of cell death GO:0010942 224 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
circulatory system process GO:0003013 197 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.016
carbohydrate metabolic process GO:0005975 230 0.016
exocytosis GO:0006887 121 0.016
fat cell differentiation GO:0045444 160 0.016
antimicrobial peptide production GO:0002775 2 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of organelle organization GO:0033043 289 0.016
ras protein signal transduction GO:0007265 77 0.016
gonad development GO:0008406 141 0.016
digestive tract development GO:0048565 190 0.016
Zebrafish
positive regulation of innate immune response GO:0045089 80 0.016
regulation of protein kinase activity GO:0045859 232 0.016
striated muscle myosin thick filament assembly GO:0071688 1 0.016
regulation of hormone levels GO:0010817 211 0.016
negative regulation of multi organism process GO:0043901 68 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
positive regulation of protein transport GO:0051222 93 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
covalent chromatin modification GO:0016569 163 0.016
skin development GO:0043588 220 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
skeletal myofibril assembly GO:0014866 4 0.016
limb morphogenesis GO:0035108 149 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
negative regulation of secretion by cell GO:1903531 54 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
leukocyte proliferation GO:0070661 172 0.015
response to oxidative stress GO:0006979 123 0.015
stem cell development GO:0048864 219 0.015
cellular response to inorganic substance GO:0071241 37 0.015
negative regulation of immune effector process GO:0002698 55 0.015
locomotory behavior GO:0007626 195 0.015
cytokine secretion GO:0050663 72 0.015
hormone metabolic process GO:0042445 86 0.015
peptide transport GO:0015833 133 0.015
regulation of cell growth GO:0001558 91 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
retinoid metabolic process GO:0001523 24 0.015
bone mineralization GO:0030282 54 0.015
myosin filament assembly GO:0031034 2 0.015
lipid homeostasis GO:0055088 63 0.015
organ growth GO:0035265 117 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.014
regulation of keratinocyte differentiation GO:0045616 11 0.014
positive regulation of protein secretion GO:0050714 52 0.014
limb development GO:0060173 166 0.014
inflammatory response GO:0006954 244 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
dna repair GO:0006281 107 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
tissue homeostasis GO:0001894 115 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
regulation of feeding behavior GO:0060259 3 0.014
blastocyst development GO:0001824 80 0.014
negative regulation of cell cycle GO:0045786 123 0.014
wound healing GO:0042060 157 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
positive regulation of antimicrobial humoral response GO:0002760 2 0.014
divalent inorganic cation transport GO:0072511 178 0.014
negative regulation of molecular function GO:0044092 258 0.014
multicellular organismal signaling GO:0035637 91 0.014
cell recognition GO:0008037 83 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
intracellular protein transport GO:0006886 204 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of chloride transport GO:2001225 2 0.014
cellular response to dna damage stimulus GO:0006974 207 0.013
membrane organization GO:0061024 245 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
regulation of protein stability GO:0031647 52 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of hydrolase activity GO:0051336 246 0.013
regulation of transmembrane transport GO:0034762 128 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
myosin filament organization GO:0031033 3 0.013
antibacterial peptide biosynthetic process GO:0002780 2 0.013
extracellular matrix organization GO:0030198 147 0.013
homeostasis of number of cells GO:0048872 210 0.013
appendage morphogenesis GO:0035107 149 0.013
cell growth GO:0016049 130 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
muscle cell development GO:0055001 133 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
regulation of blood vessel size GO:0050880 56 0.013
alpha beta t cell activation GO:0046631 91 0.013
steroid metabolic process GO:0008202 119 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
t cell proliferation GO:0042098 120 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
negative regulation of cytokine production GO:0001818 84 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
positive regulation of keratinocyte proliferation GO:0010838 4 0.013
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.013
connective tissue development GO:0061448 179 0.013
organic anion transport GO:0015711 137 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
urogenital system development GO:0001655 261 0.012
chromatin modification GO:0016568 187 0.012
chromatin organization GO:0006325 206 0.012
striated muscle cell development GO:0055002 125 0.012
ameboidal type cell migration GO:0001667 128 0.012
neuronal action potential GO:0019228 54 0.012
positive regulation of lymphocyte differentiation GO:0045621 61 0.012
circadian rhythm GO:0007623 114 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
regulation of cell cycle process GO:0010564 160 0.012
skeletal system morphogenesis GO:0048705 203 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.012
sphingolipid metabolic process GO:0006665 45 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
regulation of ossification GO:0030278 112 0.012
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.012
neuron apoptotic process GO:0051402 142 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of neuron differentiation GO:0045664 281 0.012
intracellular mrna localization GO:0008298 4 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
molting cycle GO:0042303 90 0.012
diterpenoid metabolic process GO:0016101 24 0.012
sensory perception GO:0007600 245 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
cell type specific apoptotic process GO:0097285 268 0.012
chemotaxis GO:0006935 247 0.012
innate immune response activating signal transduction GO:0002758 50 0.012
canonical wnt signaling pathway GO:0060070 130 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
regulation of kinase activity GO:0043549 249 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
phospholipid metabolic process GO:0006644 87 0.011
lipid transport GO:0006869 98 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
icosanoid biosynthetic process GO:0046456 15 0.011
cellular protein complex assembly GO:0043623 116 0.011
translation GO:0006412 93 0.011
regulation of epidermal cell differentiation GO:0045604 21 0.011
development of primary sexual characteristics GO:0045137 143 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
actin cytoskeleton organization GO:0030036 220 0.011
calcium ion homeostasis GO:0055074 127 0.011
rhythmic process GO:0048511 174 0.011
negative regulation of t cell activation GO:0050868 65 0.011
response to radiation GO:0009314 165 0.011
actin filament organization GO:0007015 113 0.011
kidney development GO:0001822 213 0.011
amide transport GO:0042886 138 0.011
organophosphate catabolic process GO:0046434 232 0.011
anion transport GO:0006820 177 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
myeloid cell differentiation GO:0030099 233 0.011
cellular response to external stimulus GO:0071496 88 0.011
cell fate commitment GO:0045165 210 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
g1 s transition of mitotic cell cycle GO:0000082 57 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.011
nucleoside metabolic process GO:0009116 246 0.011
myeloid leukocyte activation GO:0002274 83 0.011
response to extracellular stimulus GO:0009991 127 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
cholesterol transport GO:0030301 38 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
interspecies interaction between organisms GO:0044419 83 0.011
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.011
t cell receptor signaling pathway GO:0050852 46 0.011
cellular response to antibiotic GO:0071236 4 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
negative regulation of protein maturation GO:1903318 79 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
cell maturation GO:0048469 127 0.011
stem cell differentiation GO:0048863 268 0.011
lateral inhibition GO:0046331 1 0.011
cholesterol homeostasis GO:0042632 44 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
nucleoside catabolic process GO:0009164 206 0.010
neutral lipid metabolic process GO:0006638 57 0.010
pattern recognition receptor signaling pathway GO:0002221 47 0.010
female gamete generation GO:0007292 74 0.010
epithelial cell migration GO:0010631 63 0.010
alcohol biosynthetic process GO:0046165 43 0.010
regulation of ion transmembrane transporter activity GO:0032412 54 0.010
positive regulation of kinase activity GO:0033674 155 0.010
developmental cell growth GO:0048588 84 0.010
positive regulation of chemokine secretion GO:0090197 4 0.010
positive regulation of cytokine secretion GO:0050715 41 0.010
positive regulation of t cell differentiation GO:0045582 52 0.010
regulation of antimicrobial humoral response GO:0002759 3 0.010
positive regulation of t cell activation GO:0050870 101 0.010
cholesterol metabolic process GO:0008203 56 0.010
sperm motility GO:0030317 47 0.010
neuron death GO:0070997 154 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
cellular response to starvation GO:0009267 57 0.010
peptide secretion GO:0002790 114 0.010
negative regulation of keratinocyte differentiation GO:0045617 4 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
retina homeostasis GO:0001895 23 0.010
regulation of engulfment of apoptotic cell GO:1901074 2 0.010
terpenoid metabolic process GO:0006721 25 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
myelination GO:0042552 74 0.010
regulation of protein catabolic process GO:0042176 108 0.010
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.010
hepaticobiliary system development GO:0061008 67 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
response to endoplasmic reticulum stress GO:0034976 53 0.010
lateral line system development GO:0048925 1 0.010

Agr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.016
musculoskeletal system disease DOID:17 0 0.015
inherited metabolic disorder DOID:655 0 0.013
respiratory system disease DOID:1579 0 0.012
lower respiratory tract disease DOID:0050161 0 0.012
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
bone development disease DOID:0080006 0 0.012
muscular disease DOID:0080000 0 0.012