Mus musculus

18 known processes

Ear6

eosinophil-associated, ribonuclease A family, member 6

Ear6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.059
regulation of cellular ketone metabolic process GO:0010565 66 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.053
cellular amino acid metabolic process GO:0006520 103 0.051
cellular amine metabolic process GO:0044106 44 0.047
defense response to other organism GO:0098542 197 0.047
Human Mouse
amine metabolic process GO:0009308 45 0.046
immune effector process GO:0002252 321 0.039
regulation of cytokine production GO:0001817 266 0.039
cytokine production GO:0001816 319 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
response to organonitrogen compound GO:0010243 246 0.034
regulation of cell activation GO:0050865 289 0.034
sensory perception GO:0007600 245 0.033
response to lipopolysaccharide GO:0032496 128 0.033
mapk cascade GO:0000165 281 0.033
macromolecule catabolic process GO:0009057 281 0.032
Mouse
cellular lipid metabolic process GO:0044255 323 0.032
cellular homeostasis GO:0019725 240 0.032
Mouse
regulation of defense response GO:0031347 233 0.031
cation transport GO:0006812 399 0.031
innate immune response GO:0045087 157 0.031
Human
oxidation reduction process GO:0055114 342 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
positive regulation of protein modification process GO:0031401 299 0.029
inflammatory response GO:0006954 244 0.029
positive regulation of cytokine production GO:0001819 174 0.029
negative regulation of molecular function GO:0044092 258 0.028
defense response to bacterium GO:0042742 119 0.028
Human Mouse
cellular response to lipid GO:0071396 145 0.028
purine containing compound metabolic process GO:0072521 311 0.027
ion transmembrane transport GO:0034220 361 0.026
leukocyte differentiation GO:0002521 342 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
Mouse
activation of immune response GO:0002253 138 0.026
reactive oxygen species metabolic process GO:0072593 84 0.025
regulation of mapk cascade GO:0043408 248 0.025
heterocycle catabolic process GO:0046700 280 0.025
Mouse
aromatic compound catabolic process GO:0019439 286 0.025
Mouse
cellular chemical homeostasis GO:0055082 215 0.024
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.024
myeloid cell differentiation GO:0030099 233 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
transmembrane transport GO:0055085 412 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.024
peptidyl amino acid modification GO:0018193 336 0.023
regulation of hydrolase activity GO:0051336 246 0.023
regulation of transferase activity GO:0051338 263 0.023
t cell activation GO:0042110 289 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
nucleotide metabolic process GO:0009117 332 0.023
leukocyte mediated immunity GO:0002443 174 0.022
regulation of organelle organization GO:0033043 289 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
Mouse
cellular response to biotic stimulus GO:0071216 92 0.022
regulation of homeostatic process GO:0032844 182 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
cation transmembrane transport GO:0098655 266 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
regulation of membrane potential GO:0042391 192 0.021
action potential GO:0001508 78 0.021
male gamete generation GO:0048232 285 0.021
lipid biosynthetic process GO:0008610 179 0.021
regulation of protein kinase activity GO:0045859 232 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
cell type specific apoptotic process GO:0097285 268 0.021
protein maturation GO:0051604 176 0.021
regulation of kinase activity GO:0043549 249 0.020
regulation of secretion by cell GO:1903530 249 0.020
ossification GO:0001503 216 0.020
regulation of secretion GO:0051046 274 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
carbohydrate metabolic process GO:0005975 230 0.020
chemotaxis GO:0006935 247 0.020
Human Mouse
apoptotic signaling pathway GO:0097190 306 0.020
gland development GO:0048732 330 0.020
regulation of proteolysis GO:0030162 164 0.020
regulation of protein localization GO:0032880 231 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
lymphocyte differentiation GO:0030098 242 0.019
rho protein signal transduction GO:0007266 32 0.019
leukocyte proliferation GO:0070661 172 0.019
regulation of leukocyte mediated immunity GO:0002703 104 0.019
negative regulation of immune system process GO:0002683 209 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
protein processing GO:0016485 163 0.019
positive regulation of defense response GO:0031349 124 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
transmission of nerve impulse GO:0019226 76 0.019
immune response regulating signaling pathway GO:0002764 125 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
regulation of response to wounding GO:1903034 189 0.018
protein catabolic process GO:0030163 221 0.018
nitrogen compound transport GO:0071705 271 0.018
multicellular organismal signaling GO:0035637 91 0.018
response to nutrient levels GO:0031667 109 0.018
Mouse
maintenance of location GO:0051235 89 0.018
cell adhesion GO:0007155 329 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
ras protein signal transduction GO:0007265 77 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
membrane organization GO:0061024 245 0.017
angiogenesis GO:0001525 201 0.017
Mouse
leukocyte migration GO:0050900 124 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
response to acid chemical GO:0001101 111 0.017
regulation of t cell activation GO:0050863 170 0.017
skeletal system development GO:0001501 356 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
response to organic cyclic compound GO:0014070 198 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
cation homeostasis GO:0055080 212 0.017
spermatogenesis GO:0007283 284 0.017
response to extracellular stimulus GO:0009991 127 0.017
Mouse
regulation of protein transport GO:0051223 163 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
neuronal action potential GO:0019228 54 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of cell migration GO:0030334 219 0.016
regulation of cell cycle GO:0051726 281 0.016
muscle cell differentiation GO:0042692 261 0.016
regulation of ion transport GO:0043269 215 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
anion transport GO:0006820 177 0.016
positive regulation of transferase activity GO:0051347 167 0.016
sequestering of calcium ion GO:0051208 18 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
protein secretion GO:0009306 111 0.016
homeostasis of number of cells GO:0048872 210 0.016
cellular response to amino acid stimulus GO:0071230 29 0.016
glucose homeostasis GO:0042593 128 0.016
Mouse
striated muscle tissue development GO:0014706 293 0.015
wound healing GO:0042060 157 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
b cell activation GO:0042113 161 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
cytoplasmic transport GO:0016482 234 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
regulation of cell motility GO:2000145 236 0.015
fat cell differentiation GO:0045444 160 0.015
defense response to gram positive bacterium GO:0050830 50 0.015
Human
anatomical structure homeostasis GO:0060249 145 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
regulation of hormone levels GO:0010817 211 0.015
dna metabolic process GO:0006259 303 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
tissue homeostasis GO:0001894 115 0.015
positive regulation of kinase activity GO:0033674 155 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
nucleoside metabolic process GO:0009116 246 0.015
muscle tissue development GO:0060537 308 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
blood vessel morphogenesis GO:0048514 285 0.014
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.014
carbohydrate homeostasis GO:0033500 128 0.014
Mouse
cellular metal ion homeostasis GO:0006875 151 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
blood circulation GO:0008015 195 0.014
metal ion homeostasis GO:0055065 189 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
cellular response to acid chemical GO:0071229 68 0.014
positive regulation of secretion GO:0051047 130 0.014
adaptive immune response GO:0002250 155 0.014
regulation of inflammatory response GO:0050727 147 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
response to growth factor GO:0070848 198 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
regulation of multi organism process GO:0043900 111 0.014
sequestering of metal ion GO:0051238 19 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
divalent inorganic cation transport GO:0072511 178 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
microtubule based process GO:0007017 236 0.014
regulation of intracellular transport GO:0032386 159 0.014
synaptic transmission GO:0007268 329 0.014
cell activation involved in immune response GO:0002263 126 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
nucleotide catabolic process GO:0009166 217 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
endocytosis GO:0006897 168 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
negative regulation of protein modification process GO:0031400 163 0.013
calcium ion homeostasis GO:0055074 127 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of ossification GO:0030278 112 0.013
protein ubiquitination GO:0016567 171 0.013
positive regulation of cell death GO:0010942 224 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of cell projection organization GO:0031344 206 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of cell activation GO:0050867 158 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
response to inorganic substance GO:0010035 96 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
positive regulation of nervous system development GO:0051962 221 0.013
positive regulation of protein transport GO:0051222 93 0.013
response to amino acid GO:0043200 37 0.013
wnt signaling pathway GO:0016055 188 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
regulation of body fluid levels GO:0050878 162 0.013
organic anion transport GO:0015711 137 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
alcohol metabolic process GO:0006066 116 0.012
camera type eye development GO:0043010 266 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
extracellular matrix organization GO:0030198 147 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
axonogenesis GO:0007409 274 0.012
regulation of cell adhesion GO:0030155 154 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.012
circulatory system process GO:0003013 197 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
lymphocyte proliferation GO:0046651 164 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
positive regulation of cell development GO:0010720 237 0.012
humoral immune response GO:0006959 57 0.012
Human Mouse
regulation of anatomical structure size GO:0090066 178 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
positive regulation of innate immune response GO:0045089 80 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
organelle fission GO:0048285 170 0.012
protein targeting GO:0006605 143 0.012
immune response activating signal transduction GO:0002757 116 0.012
detection of stimulus GO:0051606 84 0.012
negative regulation of cell activation GO:0050866 111 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
purine containing compound catabolic process GO:0072523 213 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
fertilization GO:0009566 127 0.011
developmental maturation GO:0021700 193 0.011
regulation of protein maturation GO:1903317 96 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
positive regulation of immune effector process GO:0002699 107 0.011
methylation GO:0032259 134 0.011
skin development GO:0043588 220 0.011
regulation of protein catabolic process GO:0042176 108 0.011
small molecule biosynthetic process GO:0044283 132 0.011
dephosphorylation GO:0016311 129 0.011
regulation of blood pressure GO:0008217 93 0.011
monosaccharide metabolic process GO:0005996 106 0.011
divalent metal ion transport GO:0070838 172 0.011
extracellular structure organization GO:0043062 148 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
negative regulation of cytokine production GO:0001818 84 0.011
cytokine secretion GO:0050663 72 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
germ cell development GO:0007281 185 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of t cell proliferation GO:0042129 92 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
Mouse
rhythmic process GO:0048511 174 0.011
response to radiation GO:0009314 165 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
glycerolipid metabolic process GO:0046486 122 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of transmembrane transport GO:0034762 128 0.011
nuclear division GO:0000280 158 0.011
fatty acid metabolic process GO:0006631 121 0.011
regulation of protein secretion GO:0050708 82 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
positive regulation of cell motility GO:2000147 116 0.011
hexose metabolic process GO:0019318 98 0.011
forebrain development GO:0030900 302 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
ear development GO:0043583 200 0.011
regulation of protein processing GO:0070613 96 0.011
locomotory behavior GO:0007626 195 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
cell killing GO:0001906 67 0.011
regulation of feeding behavior GO:0060259 3 0.011
regulation of metal ion transport GO:0010959 106 0.011
organophosphate catabolic process GO:0046434 232 0.011
steroid metabolic process GO:0008202 119 0.011
skeletal system morphogenesis GO:0048705 203 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
response to insulin GO:0032868 100 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
epidermis development GO:0008544 187 0.011
regulation of cytokine secretion GO:0050707 61 0.011
regulation of cell cycle process GO:0010564 160 0.011
sensory perception of chemical stimulus GO:0007606 51 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
lipid localization GO:0010876 126 0.010
regulation of neuron differentiation GO:0045664 281 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
stem cell differentiation GO:0048863 268 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
nuclear transport GO:0051169 139 0.010
defense response to virus GO:0051607 68 0.010
single organism cell adhesion GO:0098602 156 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
ameboidal type cell migration GO:0001667 128 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
t cell differentiation GO:0030217 174 0.010
negative regulation of protein maturation GO:1903318 79 0.010
interspecies interaction between organisms GO:0044419 83 0.010
cellular response to external stimulus GO:0071496 88 0.010
Mouse
organelle localization GO:0051640 179 0.010
adult behavior GO:0030534 135 0.010
lipid transport GO:0006869 98 0.010
urogenital system development GO:0001655 261 0.010
exocytosis GO:0006887 121 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010

Ear6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012