|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.772
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.733
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.559
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.539
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.538
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.483
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.471
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.445
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.444
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.418
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.414
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.385
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.384
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.374
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.363
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.355
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.353
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.336
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.328
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.309
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.308
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.296
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.277
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.268
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.253
|
|
|
|
cilium assembly
|
GO:0042384 |
81 |
0.250
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.246
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.244
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.231
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.225
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.224
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.222
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.218
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.217
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.215
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.214
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.208
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.200
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.199
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.194
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.189
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.189
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.184
|
Human |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.182
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.180
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.172
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.172
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.172
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.170
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.169
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.169
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.168
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.167
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.167
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.166
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.166
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.164
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.164
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.163
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.162
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.159
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.157
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.156
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.156
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.152
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.152
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
22 |
0.152
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.152
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.152
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.150
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.149
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.148
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.146
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.145
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.140
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.140
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.140
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.140
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.139
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.136
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.135
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.133
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.133
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.131
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.129
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.127
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.127
|
Worm |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.126
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.126
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.123
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.122
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.121
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.120
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.119
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.119
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.119
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.119
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.118
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.117
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.116
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.116
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.116
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.115
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.115
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.114
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.114
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.113
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.113
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.112
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.112
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.111
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.110
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.110
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.110
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.109
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.108
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.108
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.107
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.107
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.106
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.105
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.104
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.104
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.103
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.103
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.103
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.102
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.101
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.101
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.100
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.099
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.098
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.097
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.097
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.096
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.096
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.096
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.095
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.095
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.093
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.092
|
|
|
|
vacuole organization
|
GO:0007033 |
38 |
0.092
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.092
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.092
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.091
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.091
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.091
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.090
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.088
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.087
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.086
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.086
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.084
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.084
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.083
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.083
|
|
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.082
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.082
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.082
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.082
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.081
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.081
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.081
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.081
|
Worm |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.080
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.080
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.079
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.079
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.078
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.078
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.078
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.078
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.077
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.077
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.076
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.075
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.075
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.075
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.075
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.074
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.074
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.074
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.074
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.074
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.073
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.073
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.073
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.072
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.072
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.072
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.071
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.071
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.071
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.071
|
|
|
|
maintenance of protein location in nucleus
|
GO:0051457 |
2 |
0.070
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.070
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.070
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.070
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.070
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.069
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.069
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.068
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.068
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.067
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.067
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.067
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.066
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.066
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.065
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.065
|
Human |
|
|
nuclear import
|
GO:0051170 |
95 |
0.064
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.064
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.063
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.063
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.063
|
Worm |
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.062
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.062
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.062
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.062
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.061
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.061
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.061
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.060
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.060
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.060
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.060
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.060
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.060
|
|
|
|
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045899 |
2 |
0.059
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.059
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.059
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.059
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.059
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.059
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.059
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.058
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.058
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.058
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.058
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.058
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.058
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.057
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.057
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.057
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.056
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.056
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.056
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.056
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.056
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.055
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.055
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.055
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.054
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.054
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.054
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.053
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.053
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.053
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.053
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.053
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.053
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.053
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.053
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.053
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.053
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.053
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.053
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.053
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.052
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.052
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.052
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.052
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.052
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.052
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.051
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.051
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.051
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.051
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.050
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.050
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.050
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.050
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.050
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.050
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.048
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.047
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.047
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.047
|
|
|
|
regulation of b cell tolerance induction
|
GO:0002661 |
2 |
0.047
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.047
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.047
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.046
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.046
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.046
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.046
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.046
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.046
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.046
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.045
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.045
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.045
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.045
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.045
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.045
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.045
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.045
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.044
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.044
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.044
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.044
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.044
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.044
|
|
|
|
bronchus morphogenesis
|
GO:0060434 |
2 |
0.044
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.044
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.043
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.043
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.043
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.043
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.043
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.043
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.043
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.043
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.043
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.043
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.042
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.042
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.042
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.042
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.042
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.042
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.042
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.042
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.042
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.042
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.041
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.041
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.041
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.041
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.041
|
|
|
|
lens fiber cell apoptotic process
|
GO:1990086 |
4 |
0.040
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.040
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
3 |
0.040
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.040
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.040
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.039
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.039
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.039
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.039
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.039
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.039
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.038
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.038
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.038
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.038
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.037
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.037
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.037
|
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.037
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.037
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.037
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.036
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.036
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.036
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.036
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.036
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.036
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.036
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.035
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.035
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.035
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.035
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.035
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.035
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.035
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.035
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
2 |
0.035
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.035
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.035
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.035
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.035
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.034
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.034
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.034
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.034
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.034
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.034
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.034
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.034
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.034
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.034
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.034
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.034
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.033
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.033
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.033
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.033
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.033
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.033
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.033
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.033
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.033
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.033
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.033
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.032
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.032
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.032
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.032
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.032
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.032
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.032
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.032
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.032
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.032
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.032
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.032
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.032
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.032
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.031
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.031
|
|
|
|
positive regulation of b cell tolerance induction
|
GO:0002663 |
2 |
0.031
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.031
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.031
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.031
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.031
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.031
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.031
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.031
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.031
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.030
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.030
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.030
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.030
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.030
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
37 |
0.030
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.030
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.029
|
Zebrafish |
|
|
genitalia development
|
GO:0048806 |
37 |
0.029
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.029
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.029
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.029
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.029
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.029
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.029
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.029
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.029
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.029
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.029
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.029
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.029
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.029
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.029
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.029
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.028
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.028
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.028
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.028
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.028
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.028
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.028
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.028
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.028
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.028
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.028
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.027
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.027
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.027
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.027
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.027
|
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
24 |
0.027
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.027
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.027
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.027
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.027
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.027
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.027
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.027
|
|
|
|
regulation of anti mullerian hormone signaling pathway
|
GO:1902612 |
1 |
0.027
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.027
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.027
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.027
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.027
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.027
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.026
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.026
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.026
|
|
