|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.933
|
|
|
|
hippo signaling
|
GO:0035329 |
11 |
0.825
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.742
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.732
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.731
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.730
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.729
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.642
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.579
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.566
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.561
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.540
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.473
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.470
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.461
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.442
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.439
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.424
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.422
|
|
|
|
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade
|
GO:0038168 |
1 |
0.408
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.401
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.378
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.348
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.312
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.293
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.287
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.264
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.260
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.260
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.259
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.254
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.252
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.249
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.244
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.244
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.237
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.230
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.228
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.220
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.220
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.220
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.218
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.212
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.208
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.205
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.202
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.201
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.197
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.195
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.194
|
Worm |
|
|
molting cycle
|
GO:0042303 |
90 |
0.192
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.191
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.191
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.191
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.186
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.184
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.184
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.179
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.178
|
Human |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.177
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.175
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.173
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.172
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.171
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.167
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.165
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.164
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.164
|
Worm |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.163
|
Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.162
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.161
|
|
|
|
hepatocyte apoptotic process
|
GO:0097284 |
11 |
0.161
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.159
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.159
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.155
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.154
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.154
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.154
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.151
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.151
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.150
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.148
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.147
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.147
|
Mouse |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.145
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.145
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.144
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.144
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.143
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.142
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.141
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.139
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.138
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.135
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.134
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.134
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.134
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.134
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.133
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.133
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.131
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.131
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.125
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.124
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.122
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.117
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.117
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.116
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.116
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.115
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.114
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.113
|
Human |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.113
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.112
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.112
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.112
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.111
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.109
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.109
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.108
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.108
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.108
|
Human |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.107
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.106
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.105
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.104
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.104
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.104
|
Human |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.104
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.103
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.102
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.101
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.100
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.099
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.099
|
Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.099
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.099
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.098
|
Mouse |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.098
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.097
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.097
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.096
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.096
|
Worm |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.096
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.096
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.095
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.094
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.093
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.091
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.090
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.090
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.088
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.088
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.087
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.086
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.085
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.085
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.085
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.085
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.085
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.085
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.084
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.084
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.084
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.083
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.083
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.083
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.083
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.082
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.081
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.081
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.081
|
Human |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.080
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.080
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.079
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.078
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.078
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.078
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.077
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.077
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.076
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.076
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.075
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.075
|
Human |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.075
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.075
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.075
|
Mouse |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.074
|
Human |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.074
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.073
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.073
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.073
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.072
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.072
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.072
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.072
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.072
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.071
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.071
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.071
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.070
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.069
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.069
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.069
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.068
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.068
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.068
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.066
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.066
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.066
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.066
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.066
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.065
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.064
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.063
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.063
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.063
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.062
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.061
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.061
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.060
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.059
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.058
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.058
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.058
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.057
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.057
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.057
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.057
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.056
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.056
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.056
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.056
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.056
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.055
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.055
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.054
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.054
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.054
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.054
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.054
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.054
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.053
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.053
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.053
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.053
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.053
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.053
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.052
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.052
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.052
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.052
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.052
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.052
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.052
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.052
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.052
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.051
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.051
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.051
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.051
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.051
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.050
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.050
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.050
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.050
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.050
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.049
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.049
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.049
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.049
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.049
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.049
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.049
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.048
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.048
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.047
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.047
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.047
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.046
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.046
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.046
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.046
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.046
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.046
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.046
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.046
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.045
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.045
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.045
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.045
|
|
|
|
epidermal growth factor receptor signaling pathway via positive regulation of nf kappab transcription factor activity
|
GO:0038167 |
1 |
0.045
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.045
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.045
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.044
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.044
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.044
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.044
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.044
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.044
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.044
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.043
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.043
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.043
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.043
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.043
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.043
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.043
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.043
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.043
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.042
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.042
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.042
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.042
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.042
|
Mouse |
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.042
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.042
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.042
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.042
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.042
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.042
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.041
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.041
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.041
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.041
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.041
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.041
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.041
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.040
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.040
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.040
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.040
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.040
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.040
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.040
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.040
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.040
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.040
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.040
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
28 |
0.039
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.039
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.039
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.039
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.039
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.039
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.039
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.038
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.038
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.038
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.038
|
Worm |
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.038
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.038
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.038
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.038
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.038
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.038
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.038
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.038
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.037
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.037
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.037
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.037
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.037
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.037
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.037
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.037
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.037
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.037
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.037
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.037
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.037
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.037
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
27 |
0.036
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.036
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.036
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.036
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.036
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.036
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.036
|
|
|
|
cellular biogenic amine metabolic process
|
GO:0006576 |
28 |
0.036
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.036
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.036
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.036
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.036
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.036
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.036
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.036
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.036
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.035
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.035
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
4 |
0.035
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.035
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.035
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.035
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.035
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.035
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.035
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.035
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.035
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.034
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.034
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.034
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.034
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.034
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.034
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.034
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.034
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.034
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.033
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.033
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.033
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
3 |
0.033
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.033
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.033
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.033
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.033
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.033
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.033
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.032
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.032
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.032
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.032
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.032
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.032
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.032
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.032
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.031
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.031
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.031
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.031
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.031
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.031
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.031
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.031
|
|
|
|
trachea development
|
GO:0060438 |
18 |
0.031
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.031
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.031
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.031
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.030
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.030
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.030
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.030
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.030
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.030
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.030
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.029
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.029
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.029
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.029
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.029
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.029
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.029
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.029
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.029
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.029
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.028
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.028
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.028
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.028
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.028
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.028
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.028
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.028
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.028
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.027
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.027
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.027
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.027
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.027
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.027
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.027
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.027
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.027
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.027
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.027
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.027
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.027
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.027
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.027
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.027
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.027
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.027
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.027
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.027
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.027
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.026
|
|
