|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.755
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.742
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.717
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.704
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.648
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.647
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.630
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.582
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.563
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.491
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.489
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.481
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.478
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.468
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.462
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.457
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.450
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.447
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.415
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.414
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.400
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.391
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.389
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.381
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.361
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.316
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.297
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.293
|
|
|
|
learning
|
GO:0007612 |
98 |
0.275
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.271
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.264
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.262
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.261
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.261
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.260
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.257
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.255
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.253
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.249
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.236
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.235
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.234
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.234
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.230
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.223
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.223
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.222
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.221
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.217
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.216
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.214
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.213
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.212
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.206
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.205
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.204
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.203
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.203
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.196
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.196
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.192
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.189
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.188
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.186
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.186
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.185
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.183
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.182
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.181
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.181
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.177
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.176
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.176
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.175
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.174
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.171
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.169
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.168
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.167
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.165
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.162
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.162
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.159
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.158
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.156
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.156
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.155
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.153
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.152
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.152
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.150
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.149
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.146
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.145
|
Mouse |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.143
|
|
|
|
memory
|
GO:0007613 |
58 |
0.141
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.141
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.140
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.139
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.138
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.137
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.137
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.132
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.132
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.131
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.131
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.130
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.129
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.129
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.128
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.126
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.125
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.124
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.123
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.122
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.121
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.117
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.117
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.117
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.117
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.117
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
2 |
0.116
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.115
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.114
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.113
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.112
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.112
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.111
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.110
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.109
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.106
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.104
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.104
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.102
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.102
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.101
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.101
|
Mouse |
|
|
axon guidance
|
GO:0007411 |
141 |
0.099
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.099
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.099
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.098
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.098
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.098
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.097
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.097
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.097
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.097
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.097
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.097
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.097
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.096
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.096
|
|
|
|
mitral valve development
|
GO:0003174 |
4 |
0.095
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.095
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.093
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.093
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.092
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.092
|
|
|
|
establishment of endothelial blood brain barrier
|
GO:0014045 |
3 |
0.090
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.090
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.089
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.088
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.088
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.087
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.087
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.087
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.086
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.086
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.084
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.084
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.083
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.082
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.082
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.082
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.082
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.082
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.082
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.081
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.081
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.080
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.080
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.080
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.080
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.079
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.079
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.079
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.079
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.079
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.078
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.078
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.078
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.078
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.078
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.078
|
|
|
|
fear response
|
GO:0042596 |
33 |
0.077
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.076
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.075
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.075
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.075
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.075
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.075
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.074
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.074
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.074
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.074
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.074
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.074
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.073
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.073
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.073
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.073
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.073
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.073
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.073
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.073
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.072
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.072
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.072
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.072
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.072
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.071
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.071
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.070
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.070
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.069
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.069
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.069
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.069
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.068
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.068
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.067
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.067
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.066
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.066
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.066
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.066
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.065
|
Mouse |
|
|
cell maturation
|
GO:0048469 |
127 |
0.065
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.065
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.064
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.064
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.064
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.064
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.063
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.063
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.063
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.063
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.063
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.063
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.062
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.062
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.061
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.061
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.061
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.061
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.061
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.061
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.061
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.061
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.060
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.060
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.060
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.060
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.059
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.059
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.059
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.059
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.059
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.059
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.059
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.059
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.059
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.059
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.058
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.058
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.058
|
|
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.057
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.057
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.057
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.057
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.057
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.057
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.057
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.057
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.056
|
|
|
|
cranial nerve development
|
GO:0021545 |
41 |
0.056
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.056
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.056
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.056
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.056
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.055
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.055
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.055
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.055
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.055
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.055
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.054
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.054
|
|
|
|
fast calcium ion dependent exocytosis of neurotransmitter
|
GO:0098746 |
1 |
0.054
|
|
|
|
somatotropin secreting cell differentiation
|
GO:0060126 |
4 |
0.054
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.054
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.054
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.053
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.053
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.053
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.053
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.053
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.053
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.053
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.052
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.052
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.052
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.052
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.052
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.052
|
|
|
|
forebrain neuron development
|
GO:0021884 |
30 |
0.052
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.052
|
Mouse |
|
|
cell growth
|
GO:0016049 |
130 |
0.051
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.051
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.051
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.051
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.051
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.051
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.051
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.051
|
|
|
|
anatomical structure arrangement
|
GO:0048532 |
20 |
0.051
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.051
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.050
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.050
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.050
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.050
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.050
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.050
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
17 |
0.050
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.050
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.049
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.049
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.049
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.048
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.048
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.048
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.048
|
|
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.048
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.048
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.048
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.048
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.048
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.048
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.048
|
Mouse |
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.048
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.047
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.047
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.047
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.047
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
10 |
0.047
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.047
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.047
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.046
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.046
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.046
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.046
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.046
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.046
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.046
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.046
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.046
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.046
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.046
|
|
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.045
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.045
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.045
|
|
|
|
cerebellar cortex development
|
GO:0021695 |
48 |
0.045
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.045
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.045
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.045
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.045
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.045
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.045
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.044
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.044
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.044
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.044
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.044
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.044
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.044
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.043
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.043
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.043
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.043
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.043
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.043
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.043
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.043
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.042
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.042
|
|
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.042
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.042
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.042
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.042
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.041
|
|
|
|
replacement ossification
|
GO:0036075 |
26 |
0.041
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.041
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.041
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.041
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.041
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.041
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.041
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.041
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.040
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.040
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.040
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.040
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.040
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.040
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.040
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
19 |
0.040
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.040
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.040
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.040
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.040
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.040
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.039
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.039
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.039
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.039
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.039
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.039
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.039
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.038
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.038
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.038
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.038
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.038
|
Mouse |
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.038
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.038
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.037
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.037
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.037
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.037
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.037
|
|
|
|
neural retina development
|
GO:0003407 |
41 |
0.037
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.037
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.037
|
|
|
|
visual perception
|
GO:0007601 |
52 |
0.037
|
|
|
|
gonadotrophin releasing hormone neuronal migration to the hypothalamus
|
GO:0021828 |
3 |
0.037
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.037
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.036
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.036
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.036
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.036
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.036
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.036
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.036
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.036
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.036
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.036
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.036
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.036
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.036
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.036
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.036
|
|
|
|
collagen fibril organization
|
GO:0030199 |
32 |
0.036
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.035
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.035
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
4 |
0.035
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.035
|
|
|
|
optic nerve structural organization
|
GO:0021633 |
2 |
0.035
|
|
|
|
midbrain development
|
GO:0030901 |
35 |
0.035
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.035
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.035
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.035
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.035
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.035
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
4 |
0.035
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.035
|
|
|
|
retinal cone cell development
|
GO:0046549 |
8 |
0.035
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.034
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.034
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.034
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.034
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.034
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.034
|
|
|
|
positive regulation of voltage gated calcium channel activity
|
GO:1901387 |
2 |
0.034
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.034
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.034
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.034
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.034
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.034
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.034
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.034
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.033
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.033
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.033
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.033
|
|
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.033
|
|
