Mus musculus

142 known processes

Bag1

BCL2-associated athanogene 1

(Aliases: Rap46,BAG-1)

Bag1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of protein metabolic process GO:0051248 282 0.304
nucleobase containing small molecule metabolic process GO:0055086 352 0.135
purine ribonucleoside metabolic process GO:0046128 241 0.126
aromatic compound catabolic process GO:0019439 286 0.119
mitochondrion organization GO:0007005 134 0.113
intrinsic apoptotic signaling pathway GO:0097193 132 0.112
purine ribonucleotide metabolic process GO:0009150 290 0.109
purine nucleotide metabolic process GO:0006163 302 0.106
purine nucleoside metabolic process GO:0042278 241 0.103
positive regulation of apoptotic process GO:0043065 217 0.102
positive regulation of cell death GO:0010942 224 0.100
nucleotide metabolic process GO:0009117 332 0.093
positive regulation of programmed cell death GO:0043068 218 0.091
cellular amino acid metabolic process GO:0006520 103 0.082
regulation of hydrolase activity GO:0051336 246 0.082
ribose phosphate metabolic process GO:0019693 291 0.081
regulation of apoptotic signaling pathway GO:2001233 197 0.077
heterocycle catabolic process GO:0046700 280 0.076
nucleotide catabolic process GO:0009166 217 0.072
transmembrane transport GO:0055085 412 0.071
purine nucleotide catabolic process GO:0006195 211 0.071
amine metabolic process GO:0009308 45 0.067
protein maturation GO:0051604 176 0.065
ribonucleoside triphosphate metabolic process GO:0009199 220 0.063
cellular amine metabolic process GO:0044106 44 0.062
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.062
glycosyl compound metabolic process GO:1901657 246 0.059
organic cyclic compound catabolic process GO:1901361 295 0.059
nucleoside metabolic process GO:0009116 246 0.058
regulation of cellular catabolic process GO:0031329 242 0.053
protein processing GO:0016485 163 0.053
cell type specific apoptotic process GO:0097285 268 0.053
apoptotic signaling pathway GO:0097190 306 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.052
ribonucleotide metabolic process GO:0009259 291 0.049
glycosyl compound catabolic process GO:1901658 206 0.049
actin cytoskeleton organization GO:0030036 220 0.048
spermatogenesis GO:0007283 284 0.048
negative regulation of cellular protein metabolic process GO:0032269 247 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.047
ketone catabolic process GO:0042182 3 0.045
oxidation reduction process GO:0055114 342 0.045
organophosphate catabolic process GO:0046434 232 0.044
reactive oxygen species biosynthetic process GO:1903409 8 0.044
negative regulation of intracellular signal transduction GO:1902532 167 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
regulation of peptidase activity GO:0052547 96 0.043
purine containing compound catabolic process GO:0072523 213 0.041
membrane organization GO:0061024 245 0.041
nucleoside catabolic process GO:0009164 206 0.041
reactive oxygen species metabolic process GO:0072593 84 0.041
ribonucleotide catabolic process GO:0009261 208 0.040
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.040
regulation of endopeptidase activity GO:0052548 89 0.040
nitrogen compound transport GO:0071705 271 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
regulation of establishment of protein localization GO:0070201 181 0.039
purine containing compound metabolic process GO:0072521 311 0.039
organic acid biosynthetic process GO:0016053 86 0.039
organonitrogen compound catabolic process GO:1901565 264 0.038
viral budding GO:0046755 1 0.038
regulation of proteolysis GO:0030162 164 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
regulation of cellular component biogenesis GO:0044087 181 0.036
protein localization to membrane GO:0072657 108 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.035
male gamete generation GO:0048232 285 0.035
purine nucleoside catabolic process GO:0006152 205 0.035
apoptotic mitochondrial changes GO:0008637 48 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.033
regulation of protein localization GO:0032880 231 0.033
inflammatory response GO:0006954 244 0.032
negative regulation of molecular function GO:0044092 258 0.032
regulation of membrane potential GO:0042391 192 0.032
cellular ketone metabolic process GO:0042180 84 0.032
regulation of cysteine type endopeptidase activity GO:2000116 65 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
striated muscle tissue development GO:0014706 293 0.031
response to oxidative stress GO:0006979 123 0.030
protein localization to organelle GO:0033365 185 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.029
cellular modified amino acid metabolic process GO:0006575 63 0.029
mitochondrial electron transport nadh to ubiquinone GO:0006120 4 0.029
positive regulation of proteolysis GO:0045862 85 0.028
regulation of organelle organization GO:0033043 289 0.028
neuron apoptotic process GO:0051402 142 0.028
cytoplasmic transport GO:0016482 234 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.027
response to inorganic substance GO:0010035 96 0.026
Rat
regulation of protein catabolic process GO:0042176 108 0.026
macromolecule catabolic process GO:0009057 281 0.026
cation transport GO:0006812 399 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.025
regulation of cell cycle GO:0051726 281 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
intracellular protein transport GO:0006886 204 0.024
positive regulation of apoptotic signaling pathway GO:2001235 95 0.024
muscle tissue development GO:0060537 308 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
energy derivation by oxidation of organic compounds GO:0015980 77 0.023
synaptic transmission GO:0007268 329 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
mitochondrial transport GO:0006839 36 0.022
spermatid development GO:0007286 108 0.022
exosomal secretion GO:1990182 1 0.022
regulation of binding GO:0051098 111 0.022
regulation of secretion GO:0051046 274 0.022
sulfur compound metabolic process GO:0006790 100 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
blood circulation GO:0008015 195 0.021
regulation of hormone levels GO:0010817 211 0.021
endomembrane system organization GO:0010256 147 0.021
positive regulation of organelle organization GO:0010638 128 0.021
chromatin organization GO:0006325 206 0.021
gland development GO:0048732 330 0.020
regulation of ion transport GO:0043269 215 0.020
actomyosin structure organization GO:0031032 56 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
regulation of protein kinase activity GO:0045859 232 0.020
regulation of nucleoside metabolic process GO:0009118 130 0.019
organelle fission GO:0048285 170 0.019
germ cell development GO:0007281 185 0.019
coenzyme metabolic process GO:0006732 52 0.019
purine nucleoside monophosphate catabolic process GO:0009128 58 0.019
peptidyl amino acid modification GO:0018193 336 0.019
protein catabolic process GO:0030163 221 0.019
protein localization to plasma membrane GO:0072659 57 0.019
regulation of vesicle mediated transport GO:0060627 139 0.018
exocytosis GO:0006887 121 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
virion assembly GO:0019068 1 0.018
lateral inhibition GO:0046331 1 0.018
neuron death GO:0070997 154 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
regulation of protein complex assembly GO:0043254 83 0.018
aldehyde catabolic process GO:0046185 4 0.018
protein ubiquitination GO:0016567 171 0.018
ion transmembrane transport GO:0034220 361 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.017
adult behavior GO:0030534 135 0.017
regulation of secretion by cell GO:1903530 249 0.017
activation of cysteine type endopeptidase activity GO:0097202 27 0.017
regulation of intracellular transport GO:0032386 159 0.017
neurotransmitter transport GO:0006836 76 0.017
response to lipopolysaccharide GO:0032496 128 0.017
alcohol metabolic process GO:0006066 116 0.017
glutathione metabolic process GO:0006749 16 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
negative regulation of phosphorylation GO:0042326 166 0.016
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
positive regulation of endopeptidase activity GO:0010950 43 0.016
negative regulation of cellular catabolic process GO:0031330 47 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
response to oxygen levels GO:0070482 62 0.016
plasma membrane organization GO:0007009 90 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
negative regulation of protein modification process GO:0031400 163 0.016
substantia nigra development GO:0021762 2 0.016
regulation of transmembrane transport GO:0034762 128 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.016
regulation of cell migration GO:0030334 219 0.016
cytokinetic process GO:0032506 2 0.016
dephosphorylation GO:0016311 129 0.016
cytokine production GO:0001816 319 0.016
fat cell differentiation GO:0045444 160 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
interleukin 8 production GO:0032637 4 0.016
peptide transport GO:0015833 133 0.016
circulatory system process GO:0003013 197 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of anatomical structure size GO:0090066 178 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
localization within membrane GO:0051668 4 0.015
negative regulation of protein processing GO:0010955 79 0.015
cell adhesion GO:0007155 329 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
mitochondrion degradation GO:0000422 3 0.015
regulation of multi organism process GO:0043900 111 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
cardiac muscle tissue development GO:0048738 130 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.014
regulation of protein transport GO:0051223 163 0.014
microtubule based process GO:0007017 236 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.014
renal system development GO:0072001 225 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.014
atp metabolic process GO:0046034 75 0.014
regulation of atp metabolic process GO:1903578 17 0.014
regulation of defense response GO:0031347 233 0.014
urogenital system development GO:0001655 261 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
negative regulation of proteolysis GO:0045861 74 0.013
divalent metal ion transport GO:0070838 172 0.013
peptide secretion GO:0002790 114 0.013
cell growth GO:0016049 130 0.013
response to organic cyclic compound GO:0014070 198 0.013
Rat
regulation of cellular response to stress GO:0080135 159 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
epithelial cell proliferation GO:0050673 174 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
gtp catabolic process GO:0006184 143 0.013
organelle assembly GO:0070925 177 0.013
zymogen activation GO:0031638 41 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.013
amide transport GO:0042886 138 0.013
hormone secretion GO:0046879 128 0.013
ameboidal type cell migration GO:0001667 128 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.012
heart morphogenesis GO:0003007 178 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
homeostasis of number of cells GO:0048872 210 0.012
establishment of vesicle localization GO:0051650 81 0.012
cell division GO:0051301 120 0.012
muscle system process GO:0003012 141 0.012
regulation of kinase activity GO:0043549 249 0.012
endocytosis GO:0006897 168 0.012
regulation of protein maturation GO:1903317 96 0.012
small molecule biosynthetic process GO:0044283 132 0.012
negative regulation of neuron death GO:1901215 98 0.012
locomotory behavior GO:0007626 195 0.012
organic hydroxy compound transport GO:0015850 93 0.011
insulin secretion GO:0030073 89 0.011
negative regulation of endopeptidase activity GO:0010951 44 0.011
single organism cell adhesion GO:0098602 156 0.011
protein polymerization GO:0051258 57 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
skin development GO:0043588 220 0.011
positive regulation of cell development GO:0010720 237 0.011
regulation of removal of superoxide radicals GO:2000121 4 0.011
regulation of inflammatory response GO:0050727 147 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
positive regulation of protein modification process GO:0031401 299 0.011
formation of organ boundary GO:0010160 1 0.011
negative regulation of transferase activity GO:0051348 85 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
nucleoside diphosphate catabolic process GO:0009134 4 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
response to monosaccharide GO:0034284 67 0.011
negative regulation of protein maturation GO:1903318 79 0.011
protein refolding GO:0042026 1 0.011
Human
regulation of protein processing GO:0070613 96 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
ras protein signal transduction GO:0007265 77 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
establishment of organelle localization GO:0051656 122 0.011
cell fate commitment GO:0045165 210 0.011
muscle cell differentiation GO:0042692 261 0.011
response to reactive oxygen species GO:0000302 56 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
epithelial tube morphogenesis GO:0060562 303 0.010
positive regulation of peptidase activity GO:0010952 49 0.010
action potential GO:0001508 78 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
peptide hormone secretion GO:0030072 109 0.010
cellular protein complex assembly GO:0043623 116 0.010
response to radiation GO:0009314 165 0.010
regulation of cell cycle process GO:0010564 160 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
regulation of cell activation GO:0050865 289 0.010
regulation of phospholipid biosynthetic process GO:0071071 3 0.010
response to nutrient levels GO:0031667 109 0.010
fertilization GO:0009566 127 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of receptor activity GO:0010469 41 0.010

Bag1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
disease of metabolism DOID:0014667 0 0.020
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.011
inherited metabolic disorder DOID:655 0 0.010