Mus musculus

83 known processes

Lsm14a

LSM14 homolog A (SCD6, S. cerevisiae)

(Aliases: AU017544,2700023B17Rik,AA407828,Tral)

Lsm14a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peptidyl amino acid modification GO:0018193 336 0.254
negative regulation of phosphorylation GO:0042326 166 0.251
regulation of cellular amine metabolic process GO:0033238 20 0.201
negative regulation of protein metabolic process GO:0051248 282 0.178
regulation of cellular amino acid metabolic process GO:0006521 5 0.144
multicellular organism growth GO:0035264 161 0.125
stem cell differentiation GO:0048863 268 0.124
stem cell development GO:0048864 219 0.123
covalent chromatin modification GO:0016569 163 0.123
negative regulation of cellular amine metabolic process GO:0033239 1 0.121
microtubule based process GO:0007017 236 0.121
dna metabolic process GO:0006259 303 0.108
regulation of cellular ketone metabolic process GO:0010565 66 0.105
cellular amine metabolic process GO:0044106 44 0.103
response to peptide hormone GO:0043434 127 0.102
cellular amino acid metabolic process GO:0006520 103 0.096
endomembrane system organization GO:0010256 147 0.092
negative regulation of cellular protein metabolic process GO:0032269 247 0.092
organelle localization GO:0051640 179 0.091
nucleotide catabolic process GO:0009166 217 0.090
carbohydrate derivative catabolic process GO:1901136 231 0.090
regulation of secretion GO:0051046 274 0.089
negative regulation of protein modification process GO:0031400 163 0.088
regulation of cell cycle GO:0051726 281 0.083
muscle cell differentiation GO:0042692 261 0.079
macromolecule methylation GO:0043414 120 0.079
protein modification by small protein conjugation GO:0032446 187 0.078
nucleoside triphosphate metabolic process GO:0009141 230 0.078
purine ribonucleoside catabolic process GO:0046130 205 0.075
hematopoietic progenitor cell differentiation GO:0002244 143 0.075
positive regulation of secretion GO:0051047 130 0.075
histone modification GO:0016570 159 0.075
amine metabolic process GO:0009308 45 0.074
chromatin organization GO:0006325 206 0.074
nucleobase containing small molecule metabolic process GO:0055086 352 0.073
wnt signaling pathway GO:0016055 188 0.071
axonogenesis GO:0007409 274 0.069
stem cell maintenance GO:0019827 130 0.069
aromatic compound catabolic process GO:0019439 286 0.069
negative regulation of phosphorus metabolic process GO:0010563 184 0.068
oocyte construction GO:0007308 2 0.068
chromatin modification GO:0016568 187 0.068
homeostasis of number of cells GO:0048872 210 0.066
regulation of organelle organization GO:0033043 289 0.065
purine ribonucleotide catabolic process GO:0009154 208 0.063
microtubule cytoskeleton organization GO:0000226 157 0.062
positive regulation of secretion by cell GO:1903532 114 0.059
negative regulation of intracellular signal transduction GO:1902532 167 0.058
negative regulation of molecular function GO:0044092 258 0.058
nucleotide metabolic process GO:0009117 332 0.058
cell adhesion GO:0007155 329 0.056
smoothened signaling pathway GO:0007224 105 0.056
protein ubiquitination GO:0016567 171 0.056
negative regulation of protein phosphorylation GO:0001933 126 0.055
ras protein signal transduction GO:0007265 77 0.055
glycosyl compound catabolic process GO:1901658 206 0.055
vesicle organization GO:0016050 60 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.053
macromolecule catabolic process GO:0009057 281 0.053
regulation of hydrolase activity GO:0051336 246 0.053
regulation of transferase activity GO:0051338 263 0.052
response to organonitrogen compound GO:0010243 246 0.051
purine nucleoside triphosphate catabolic process GO:0009146 203 0.050
regulation of nucleoside metabolic process GO:0009118 130 0.049
establishment of organelle localization GO:0051656 122 0.049
purine containing compound catabolic process GO:0072523 213 0.049
purine containing compound metabolic process GO:0072521 311 0.048
negative regulation of dna replication GO:0008156 4 0.047
purine ribonucleotide metabolic process GO:0009150 290 0.047
neuron projection guidance GO:0097485 141 0.046
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.045
ribose phosphate metabolic process GO:0019693 291 0.045
purine nucleotide catabolic process GO:0006195 211 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.044
gtp catabolic process GO:0006184 143 0.044
protein modification by small protein conjugation or removal GO:0070647 207 0.044
protein localization to organelle GO:0033365 185 0.044
regulation of protein kinase activity GO:0045859 232 0.043
cellular ketone metabolic process GO:0042180 84 0.043
nucleoside metabolic process GO:0009116 246 0.043
regulation of wnt signaling pathway GO:0030111 123 0.042
intracellular mrna localization GO:0008298 4 0.042
regulation of kinase activity GO:0043549 249 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.042
mitotic cell cycle process GO:1903047 159 0.042
myeloid cell homeostasis GO:0002262 114 0.042
leukocyte differentiation GO:0002521 342 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.041
t cell differentiation GO:0030217 174 0.041
purine nucleotide metabolic process GO:0006163 302 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.039
rhythmic process GO:0048511 174 0.039
cell fate commitment GO:0045165 210 0.039
single organism cell adhesion GO:0098602 156 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.038
chromosome segregation GO:0007059 48 0.038
cellular component assembly involved in morphogenesis GO:0010927 139 0.037
gastrulation GO:0007369 116 0.037
regulation of hormone levels GO:0010817 211 0.037
negative regulation of kinase activity GO:0033673 81 0.037
negative regulation of phosphate metabolic process GO:0045936 184 0.037
regulation of cellular component size GO:0032535 121 0.036
canonical wnt signaling pathway GO:0060070 130 0.036
cytoplasmic transport GO:0016482 234 0.036
regulation of smoothened signaling pathway GO:0008589 58 0.036
nuclear division GO:0000280 158 0.036
ribonucleoside metabolic process GO:0009119 245 0.035
cellular macromolecule catabolic process GO:0044265 206 0.035
mapk cascade GO:0000165 281 0.035
myosin filament organization GO:0031033 3 0.034
heterocycle catabolic process GO:0046700 280 0.034
regulation of nucleotide metabolic process GO:0006140 169 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.034
organic cyclic compound catabolic process GO:1901361 295 0.033
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
myeloid cell differentiation GO:0030099 233 0.033
regulation of mapk cascade GO:0043408 248 0.032
regulation of body fluid levels GO:0050878 162 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
respiratory system development GO:0060541 190 0.031
respiratory tube development GO:0030323 167 0.031
secretory granule organization GO:0033363 20 0.031
digestive tract development GO:0048565 190 0.030
circadian rhythm GO:0007623 114 0.029
mitotic cell cycle GO:0000278 195 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
negative regulation of immune system process GO:0002683 209 0.029
regulation of secretion by cell GO:1903530 249 0.029
chemotaxis GO:0006935 247 0.029
actin cytoskeleton organization GO:0030036 220 0.029
male gamete generation GO:0048232 285 0.028
nucleoside catabolic process GO:0009164 206 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
cellular response to insulin stimulus GO:0032869 78 0.028
positive regulation of wnt signaling pathway GO:0030177 45 0.028
erk1 and erk2 cascade GO:0070371 77 0.028
t cell activation GO:0042110 289 0.028
endocytosis GO:0006897 168 0.027
morphogenesis of a branching structure GO:0001763 203 0.027
digestive tract morphogenesis GO:0048546 147 0.027
cellular response to organonitrogen compound GO:0071417 145 0.027
response to organic cyclic compound GO:0014070 198 0.027
organelle assembly GO:0070925 177 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
regulation of protein localization GO:0032880 231 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
cellular response to peptide hormone stimulus GO:0071375 92 0.026
proteasomal protein catabolic process GO:0010498 98 0.025
meiotic cell cycle GO:0051321 122 0.025
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.024
metaphase plate congression GO:0051310 2 0.024
regulation of mitotic cell cycle GO:0007346 126 0.024
positive regulation of gtpase activity GO:0043547 85 0.024
nitrogen compound transport GO:0071705 271 0.024
regulation of chromosome organization GO:0033044 83 0.024
germ cell development GO:0007281 185 0.024
negative regulation of cell proliferation GO:0008285 296 0.023
spermatogenesis GO:0007283 284 0.023
mrna metabolic process GO:0016071 84 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
mesodermal cell migration GO:0008078 4 0.023
cell division GO:0051301 120 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
regulation of cell cycle process GO:0010564 160 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
localization within membrane GO:0051668 4 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
response to peptide GO:1901652 136 0.022
wound healing GO:0042060 157 0.022
positive regulation of nervous system development GO:0051962 221 0.022
organophosphate catabolic process GO:0046434 232 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
immune effector process GO:0002252 321 0.022
negative regulation of cell cycle GO:0045786 123 0.022
apoptotic signaling pathway GO:0097190 306 0.022
cellularization GO:0007349 1 0.022
fat cell differentiation GO:0045444 160 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
regulation of protein stability GO:0031647 52 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
organelle fission GO:0048285 170 0.021
negative regulation of transferase activity GO:0051348 85 0.021
spermatid differentiation GO:0048515 115 0.021
developmental maturation GO:0021700 193 0.021
gtp metabolic process GO:0046039 144 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
protein localization to plasma membrane GO:0072659 57 0.021
lymphocyte differentiation GO:0030098 242 0.021
cell maturation GO:0048469 127 0.021
single organismal cell cell adhesion GO:0016337 131 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
digestive system development GO:0055123 200 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
positive regulation of dna templated transcription elongation GO:0032786 2 0.020
maintenance of location GO:0051235 89 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
placenta development GO:0001890 140 0.020
protein acylation GO:0043543 64 0.020
cellular lipid metabolic process GO:0044255 323 0.020
gland development GO:0048732 330 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.020
cellular response to peptide GO:1901653 92 0.020
response to growth factor GO:0070848 198 0.019
cytokine production GO:0001816 319 0.019
regulation of canonical wnt signaling pathway GO:0060828 82 0.019
meiotic nuclear division GO:0007126 115 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
morphogenesis of a branching epithelium GO:0061138 193 0.019
regulation of cell size GO:0008361 72 0.018
female gamete generation GO:0007292 74 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
circadian regulation of gene expression GO:0032922 48 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
cellular protein catabolic process GO:0044257 155 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
body fluid secretion GO:0007589 53 0.018
positive regulation of cell development GO:0010720 237 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
response to insulin GO:0032868 100 0.018
negative regulation of cell cycle process GO:0010948 69 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
cation transmembrane transport GO:0098655 266 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
learning or memory GO:0007611 148 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
regulation of actin filament based process GO:0032970 99 0.017
intracellular protein transport GO:0006886 204 0.017
ossification GO:0001503 216 0.017
spindle localization GO:0051653 22 0.017
golgi vesicle transport GO:0048193 30 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
striated muscle tissue development GO:0014706 293 0.017
plasma membrane organization GO:0007009 90 0.017
positive regulation of ras gtpase activity GO:0032320 65 0.016
negative regulation of nervous system development GO:0051961 156 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
antigen receptor mediated signaling pathway GO:0050851 64 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
response to radiation GO:0009314 165 0.016
negative regulation of wnt signaling pathway GO:0030178 73 0.016
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
positive regulation of leukocyte differentiation GO:1902107 86 0.016
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.016
oocyte axis specification GO:0007309 2 0.016
regulation of cell adhesion GO:0030155 154 0.015
lung development GO:0030324 164 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
meiotic cell cycle process GO:1903046 77 0.015
protein methylation GO:0006479 81 0.015
dna endoreduplication GO:0042023 4 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
dendrite development GO:0016358 115 0.015
rho protein signal transduction GO:0007266 32 0.014
hormone secretion GO:0046879 128 0.014
exocytosis GO:0006887 121 0.014
regulation of neuron differentiation GO:0045664 281 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
trna wobble base modification GO:0002097 2 0.014
regulation of cell motility GO:2000145 236 0.014
regionalization GO:0003002 337 0.014
regulation of exocytosis GO:0017157 61 0.014
regulation of chromatin modification GO:1903308 57 0.014
neural precursor cell proliferation GO:0061351 121 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
regulation of ras gtpase activity GO:0032318 88 0.014
mitotic nuclear division GO:0007067 48 0.013
spermatid development GO:0007286 108 0.013
regulation of system process GO:0044057 200 0.013
non canonical wnt signaling pathway GO:0035567 33 0.013
response to light stimulus GO:0009416 135 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
axon guidance GO:0007411 141 0.013
blood vessel morphogenesis GO:0048514 285 0.013
myosin filament assembly GO:0031034 2 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
epithelial cell development GO:0002064 159 0.013
atp metabolic process GO:0046034 75 0.013
phagocytosis GO:0006909 66 0.013
axon target recognition GO:0007412 4 0.012
regulation of cell projection organization GO:0031344 206 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of protein catabolic process GO:0042176 108 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of peptidyl lysine acetylation GO:2000756 22 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
positive regulation of cell cycle GO:0045787 92 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.012
camera type eye development GO:0043010 266 0.012
regulation of anatomical structure size GO:0090066 178 0.012
amide transport GO:0042886 138 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
meiotic chromosome segregation GO:0045132 19 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
negative regulation of cell cycle phase transition GO:1901988 48 0.012
regulation of cytokine production GO:0001817 266 0.012
muscle tissue development GO:0060537 308 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
positive regulation of rac protein signal transduction GO:0035022 1 0.012
internal peptidyl lysine acetylation GO:0018393 42 0.012
positive regulation of protein modification process GO:0031401 299 0.012
sensory perception GO:0007600 245 0.012
regulation of circadian rhythm GO:0042752 58 0.011
embryonic placenta development GO:0001892 98 0.011
erythrocyte differentiation GO:0030218 88 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
regulation of t cell proliferation GO:0042129 92 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
peptidyl lysine modification GO:0018205 77 0.011
sensory organ morphogenesis GO:0090596 242 0.011
interspecies interaction between organisms GO:0044419 83 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
regulation of protein complex assembly GO:0043254 83 0.011
carbohydrate metabolic process GO:0005975 230 0.011
negative regulation of myeloid cell differentiation GO:0045638 38 0.011
cellular response to lipid GO:0071396 145 0.011
peptidyl serine modification GO:0018209 83 0.011
cellular protein complex assembly GO:0043623 116 0.011
membrane organization GO:0061024 245 0.011
positive regulation of cell migration GO:0030335 109 0.011
protein polymerization GO:0051258 57 0.011
mrna splicing via spliceosome GO:0000398 43 0.011
cell cycle switching GO:0060184 1 0.011
regulation of t cell activation GO:0050863 170 0.011
forebrain development GO:0030900 302 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
transmembrane transport GO:0055085 412 0.010
negative regulation of mapk cascade GO:0043409 65 0.010
compound eye development GO:0048749 1 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
inflammatory response GO:0006954 244 0.010
protein alkylation GO:0008213 81 0.010
mrna processing GO:0006397 63 0.010
protein dna complex subunit organization GO:0071824 28 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
rna processing GO:0006396 105 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
multi multicellular organism process GO:0044706 109 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
regulation of neurotransmitter levels GO:0001505 87 0.010
internal protein amino acid acetylation GO:0006475 42 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
regulation of proteolysis GO:0030162 164 0.010
rac protein signal transduction GO:0016601 13 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
centrosome separation GO:0051299 4 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010

Lsm14a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
nervous system disease DOID:863 0 0.070
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
organ system cancer DOID:0050686 0 0.033
endocrine gland cancer DOID:170 0 0.024
sensory system disease DOID:0050155 0 0.024
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011