|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.257
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.225
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.225
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.210
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.201
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.189
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.179
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.176
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.172
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.172
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.169
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.166
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.163
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.156
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.156
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.151
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.151
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.145
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.141
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.138
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.138
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.137
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.133
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.132
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.128
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.127
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.118
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.115
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.108
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.105
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.105
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.104
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.103
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.103
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.099
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.096
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.094
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.094
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.094
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.092
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.091
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.091
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.091
|
|
|
|
regulation of fatty acid biosynthetic process
|
GO:0042304 |
12 |
0.091
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.088
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.087
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.086
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.085
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.084
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.084
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.083
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.082
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.082
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.082
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.082
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.081
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.081
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.080
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.080
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.079
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.079
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.079
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.079
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.078
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.077
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.077
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.076
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.075
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.074
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.074
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.072
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.072
|
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
23 |
0.072
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.071
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.071
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.069
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.069
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.068
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.068
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.068
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.067
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.067
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.066
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.066
|
|
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.065
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.063
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.063
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.063
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.062
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.062
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.062
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.062
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.061
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.060
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.060
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.058
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.058
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.057
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.057
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.057
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.056
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.055
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.055
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.054
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.054
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.053
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.053
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.053
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.053
|
|
|
|
cellular alcohol biosynthetic process
|
GO:0044108 |
3 |
0.052
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.052
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.052
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.052
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.051
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.051
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.051
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.051
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.050
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.050
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.049
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.049
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.049
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.049
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.048
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.048
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.048
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.048
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.048
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.048
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.047
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.047
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.047
|
|
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
3 |
0.047
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.046
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.046
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.046
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.046
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.045
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.044
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.044
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.044
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.044
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.043
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.043
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.043
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.043
|
|
|
|
cellular alcohol metabolic process
|
GO:0044107 |
3 |
0.042
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.042
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.042
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.041
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.041
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.041
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.041
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.041
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.041
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.041
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.040
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.040
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.040
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.039
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.039
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.039
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.039
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.039
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.039
|
|
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.038
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.038
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.038
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
47 |
0.038
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.038
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.038
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.037
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.037
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.037
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.037
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.037
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.037
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.037
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.037
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.036
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.036
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.036
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
43 |
0.036
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.036
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.036
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.035
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.035
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.035
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.035
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.035
|
Human |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.034
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.034
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.034
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
39 |
0.034
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.034
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.034
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.034
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.033
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.033
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.033
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.033
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.033
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.033
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.033
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.033
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.032
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.032
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.032
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.032
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.032
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.032
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.031
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.031
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.031
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.031
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.031
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.031
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.031
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.031
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.031
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.031
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.031
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.031
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.030
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.030
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.030
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.030
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.030
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.030
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.030
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.030
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.030
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.030
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.030
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.030
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.030
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.029
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.029
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.029
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.029
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.029
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.029
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.029
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.029
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.029
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.029
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.029
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.029
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.029
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.029
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.028
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.028
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.028
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.028
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.028
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.028
|
|
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
13 |
0.028
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.028
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.028
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.028
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.027
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.027
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.027
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.027
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.027
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.027
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.027
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.027
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.027
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.027
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.027
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.026
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.026
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.026
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.026
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.026
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.026
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.026
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.026
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.026
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.025
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.025
|
Human |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.025
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.025
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.025
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.025
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.025
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.025
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.025
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.025
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.025
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.025
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.025
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.025
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.025
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.024
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
29 |
0.024
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.024
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.024
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.024
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.024
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.024
|
|
|
|
regulation of cd8 positive alpha beta cytotoxic t cell extravasation
|
GO:2000452 |
2 |
0.024
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.024
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.024
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.024
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.024
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.024
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.024
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.024
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.024
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.023
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.023
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
28 |
0.023
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.023
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.023
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.023
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.023
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.023
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.023
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.023
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.022
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.022
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.022
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.022
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.022
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.022
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.022
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.022
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.022
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
1 |
0.022
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.022
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.022
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.022
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.022
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.022
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.022
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.022
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.022
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.022
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.022
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.022
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.022
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.022
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.022
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.022
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.022
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.022
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.022
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.021
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.021
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.021
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.021
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.021
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.021
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.021
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.021
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.021
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.021
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.021
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.021
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.021
|
|
|
|
negative regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030948 |
6 |
0.021
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.021
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.020
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.020
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.020
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.020
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.020
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.020
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.020
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.020
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.020
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.020
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
52 |
0.020
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.020
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.020
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.020
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.020
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.020
|
|
|
|
axonal fasciculation
|
GO:0007413 |
15 |
0.020
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.020
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.020
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.020
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.020
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.020
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.020
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.019
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.019
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.019
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.019
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.019
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.019
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.019
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.019
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.019
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.019
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.019
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.019
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.019
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.019
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.019
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.019
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.019
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.019
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.019
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.019
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.019
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
8 |
0.018
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.018
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.018
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.018
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.018
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.018
|
|
|
|
mrna transport
|
GO:0051028 |
13 |
0.018
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.018
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.018
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.018
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.018
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.018
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.018
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.018
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.018
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.018
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.018
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.018
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.017
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
80 |
0.017
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.017
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.017
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.017
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.017
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.017
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.017
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.017
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.017
|
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
3 |
0.017
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.017
|
|
|
|
nuclear export
|
GO:0051168 |
34 |
0.017
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.017
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.017
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.017
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.017
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.017
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.017
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.017
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.017
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.017
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.017
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.017
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.017
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.017
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.017
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.017
|
|
|
|
quinone metabolic process
|
GO:1901661 |
7 |
0.017
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.017
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.017
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.017
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.016
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
27 |
0.016
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.016
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.016
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.016
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.016
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.016
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.016
|
|
|
|
rna transport
|
GO:0050658 |
18 |
0.016
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.016
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.016
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.016
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.016
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.016
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.016
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.016
|
|
|
|
regulation of nlrp3 inflammasome complex assembly
|
GO:1900225 |
4 |
0.016
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.016
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.016
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.016
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.016
|
|
|
|
translation
|
GO:0006412 |
93 |
0.016
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.016
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.016
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.016
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.016
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.016
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.016
|
|
|
|
regulation of coenzyme metabolic process
|
GO:0051196 |
4 |
0.016
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.016
|
|
