Mus musculus

41 known processes

Fanca

Fanconi anemia, complementation group A

(Aliases: FACA,AW208693)

Fanca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.224
dna repair GO:0006281 107 0.207
organic cyclic compound catabolic process GO:1901361 295 0.169
dna metabolic process GO:0006259 303 0.148
meiotic nuclear division GO:0007126 115 0.096
cellular amino acid metabolic process GO:0006520 103 0.089
heterocycle catabolic process GO:0046700 280 0.082
nucleoside phosphate metabolic process GO:0006753 338 0.075
microtubule based process GO:0007017 236 0.073
nucleoside metabolic process GO:0009116 246 0.072
regulation of cell cycle GO:0051726 281 0.066
cellular ketone metabolic process GO:0042180 84 0.065
dna recombination GO:0006310 92 0.061
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
ovarian follicle development GO:0001541 40 0.058
female gonad development GO:0008585 71 0.058
mitotic cell cycle GO:0000278 195 0.057
cellular amine metabolic process GO:0044106 44 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
leukocyte mediated immunity GO:0002443 174 0.053
cellular nitrogen compound catabolic process GO:0044270 280 0.053
t cell activation GO:0042110 289 0.052
response to radiation GO:0009314 165 0.051
purine ribonucleoside catabolic process GO:0046130 205 0.050
nucleoside triphosphate catabolic process GO:0009143 205 0.050
male gamete generation GO:0048232 285 0.049
purine nucleotide catabolic process GO:0006195 211 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.049
ribonucleoside metabolic process GO:0009119 245 0.048
nucleoside phosphate catabolic process GO:1901292 222 0.048
glycosyl compound catabolic process GO:1901658 206 0.047
forebrain development GO:0030900 302 0.045
nucleoside catabolic process GO:0009164 206 0.044
lymphocyte differentiation GO:0030098 242 0.044
positive regulation of hydrolase activity GO:0051345 148 0.043
regulation of cell cycle process GO:0010564 160 0.043
negative regulation of cell proliferation GO:0008285 296 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
lymphocyte mediated immunity GO:0002449 139 0.042
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
rhythmic process GO:0048511 174 0.041
germ cell development GO:0007281 185 0.040
lateral inhibition GO:0046331 1 0.040
leukocyte differentiation GO:0002521 342 0.040
regulation of lymphocyte activation GO:0051249 240 0.038
organelle assembly GO:0070925 177 0.038
regulation of cell activation GO:0050865 289 0.038
double strand break repair GO:0006302 48 0.037
purine ribonucleotide catabolic process GO:0009154 208 0.037
regulation of cytokine production GO:0001817 266 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
blood vessel morphogenesis GO:0048514 285 0.036
multicellular organismal homeostasis GO:0048871 164 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.035
maintenance of location GO:0051235 89 0.035
oogenesis GO:0048477 56 0.035
regulation of cellular component size GO:0032535 121 0.035
nucleotide catabolic process GO:0009166 217 0.034
negative regulation of cell development GO:0010721 169 0.034
spermatogenesis GO:0007283 284 0.034
development of primary female sexual characteristics GO:0046545 73 0.034
ribonucleoside triphosphate catabolic process GO:0009203 199 0.034
purine containing compound metabolic process GO:0072521 311 0.034
ras protein signal transduction GO:0007265 77 0.034
cilium morphogenesis GO:0060271 102 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
glycosyl compound metabolic process GO:1901657 246 0.033
divalent inorganic cation transport GO:0072511 178 0.033
regulation of organelle organization GO:0033043 289 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
organophosphate catabolic process GO:0046434 232 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
nucleotide metabolic process GO:0009117 332 0.033
b cell activation GO:0042113 161 0.033
cytokine production GO:0001816 319 0.032
carbohydrate derivative catabolic process GO:1901136 231 0.032
immune effector process GO:0002252 321 0.032
positive regulation of cell development GO:0010720 237 0.031
embryonic limb morphogenesis GO:0030326 126 0.031
cellular response to biotic stimulus GO:0071216 92 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
blastocyst development GO:0001824 80 0.030
spermatid development GO:0007286 108 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
oxidation reduction process GO:0055114 342 0.030
peptidyl amino acid modification GO:0018193 336 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
lymphocyte proliferation GO:0046651 164 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
endomembrane system organization GO:0010256 147 0.029
stem cell differentiation GO:0048863 268 0.028
immunoglobulin mediated immune response GO:0016064 69 0.028
development of primary sexual characteristics GO:0045137 143 0.028
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
adaptive immune response GO:0002250 155 0.028
regulation of protein kinase activity GO:0045859 232 0.027
amine metabolic process GO:0009308 45 0.027
cell type specific apoptotic process GO:0097285 268 0.027
regulation of neuron differentiation GO:0045664 281 0.027
inflammatory response GO:0006954 244 0.027
meiotic dna repair synthesis GO:0000711 4 0.026
meiotic cell cycle GO:0051321 122 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.025
organelle fission GO:0048285 170 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
metaphase plate congression GO:0051310 2 0.025
purine containing compound catabolic process GO:0072523 213 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
female sex differentiation GO:0046660 84 0.024
negative regulation of nervous system development GO:0051961 156 0.024
regulation of secretion GO:0051046 274 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
t cell proliferation GO:0042098 120 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
regulation of adaptive immune response GO:0002819 90 0.023
aromatic compound catabolic process GO:0019439 286 0.023
skeletal system development GO:0001501 356 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.022
apoptotic signaling pathway GO:0097190 306 0.022
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.022
skeletal system morphogenesis GO:0048705 203 0.022
digestive system development GO:0055123 200 0.022
myeloid leukocyte activation GO:0002274 83 0.022
stem cell maintenance GO:0019827 130 0.022
macromolecule catabolic process GO:0009057 281 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
regulation of lymphocyte mediated immunity GO:0002706 84 0.021
regulation of anatomical structure size GO:0090066 178 0.021
regionalization GO:0003002 337 0.021
regulation of hydrolase activity GO:0051336 246 0.021
regulation of mapk cascade GO:0043408 248 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
regulation of t cell activation GO:0050863 170 0.021
gland development GO:0048732 330 0.021
cellular response to growth factor stimulus GO:0071363 197 0.020
organelle localization GO:0051640 179 0.020
response to cell cycle checkpoint signaling GO:0072396 1 0.020
ovulation cycle GO:0042698 59 0.020
cation transport GO:0006812 399 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
transmission of nerve impulse GO:0019226 76 0.020
positive regulation of nervous system development GO:0051962 221 0.020
digestive tract development GO:0048565 190 0.020
positive regulation of cell cycle process GO:0090068 61 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
calcium ion transport GO:0006816 159 0.019
camera type eye development GO:0043010 266 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
atp metabolic process GO:0046034 75 0.019
nuclear division GO:0000280 158 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
positive regulation of lymphocyte activation GO:0051251 140 0.019
appendage development GO:0048736 166 0.019
morphogenesis of a branching epithelium GO:0061138 193 0.019
negative regulation of cell cycle GO:0045786 123 0.019
regulation of binding GO:0051098 111 0.018
chemotaxis GO:0006935 247 0.018
chromatin modification GO:0016568 187 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
stem cell proliferation GO:0072089 117 0.018
female gamete generation GO:0007292 74 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
respiratory system development GO:0060541 190 0.018
regulation of cellular response to stress GO:0080135 159 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.018
bone development GO:0060348 120 0.018
cell division GO:0051301 120 0.018
t cell differentiation GO:0030217 174 0.017
cell fate commitment GO:0045165 210 0.017
action potential GO:0001508 78 0.017
regulation of defense response GO:0031347 233 0.017
exocytosis GO:0006887 121 0.017
multicellular organism growth GO:0035264 161 0.017
mapk cascade GO:0000165 281 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
sensory perception GO:0007600 245 0.017
stem cell development GO:0048864 219 0.017
transmembrane transport GO:0055085 412 0.017
membrane organization GO:0061024 245 0.017
cellularization GO:0007349 1 0.017
regulation of lymphocyte proliferation GO:0050670 117 0.017
response to peptide GO:1901652 136 0.017
anatomical structure homeostasis GO:0060249 145 0.016
embryonic digit morphogenesis GO:0042733 56 0.016
positive regulation of cell activation GO:0050867 158 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
myeloid cell differentiation GO:0030099 233 0.016
cell activation involved in immune response GO:0002263 126 0.016
mitotic cell cycle process GO:1903047 159 0.016
axonogenesis GO:0007409 274 0.016
leukocyte migration GO:0050900 124 0.016
regulation of b cell tolerance induction GO:0002661 2 0.016
dna biosynthetic process GO:0071897 22 0.016
positive regulation of t cell activation GO:0050870 101 0.016
synaptic transmission GO:0007268 329 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
cytoplasmic transport GO:0016482 234 0.016
placenta development GO:0001890 140 0.016
positive regulation of reproductive process GO:2000243 19 0.016
cell maturation GO:0048469 127 0.016
spermatid differentiation GO:0048515 115 0.016
innate immune response GO:0045087 157 0.016
regulation of membrane potential GO:0042391 192 0.015
connective tissue development GO:0061448 179 0.015
b cell mediated immunity GO:0019724 71 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
limb development GO:0060173 166 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
ion transmembrane transport GO:0034220 361 0.015
regulation of cell division GO:0051302 76 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
positive regulation of protein modification process GO:0031401 299 0.015
regulation of hormone levels GO:0010817 211 0.015
smoothened signaling pathway GO:0007224 105 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
negative regulation of immune system process GO:0002683 209 0.015
epidermis development GO:0008544 187 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.014
humoral immune response GO:0006959 57 0.014
immunoglobulin production GO:0002377 73 0.014
rho protein signal transduction GO:0007266 32 0.014
cytokine metabolic process GO:0042107 71 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
endocytosis GO:0006897 168 0.014
positive regulation of cell death GO:0010942 224 0.014
regulation of t cell proliferation GO:0042129 92 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
cilium assembly GO:0042384 81 0.014
positive regulation of immune effector process GO:0002699 107 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
molting cycle GO:0042303 90 0.014
chromatin organization GO:0006325 206 0.014
response to growth factor GO:0070848 198 0.014
multicellular organismal signaling GO:0035637 91 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
positive regulation of growth GO:0045927 104 0.014
developmental maturation GO:0021700 193 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.014
negative regulation of cell size GO:0045792 3 0.014
regulation of asymmetric cell division GO:0009786 4 0.013
alpha beta t cell activation GO:0046631 91 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
determination of left right symmetry GO:0007368 80 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
cerebral cortex development GO:0021987 86 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
dna endoreduplication GO:0042023 4 0.013
tissue remodeling GO:0048771 102 0.013
cellular homeostasis GO:0019725 240 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
cellular protein complex assembly GO:0043623 116 0.013
phagocytosis GO:0006909 66 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
regulation of system process GO:0044057 200 0.013
intracellular protein transport GO:0006886 204 0.013
lipid biosynthetic process GO:0008610 179 0.013
small molecule biosynthetic process GO:0044283 132 0.012
telencephalon development GO:0021537 186 0.012
regulation of transferase activity GO:0051338 263 0.012
cellular ion homeostasis GO:0006873 165 0.012
regulation of t cell differentiation GO:0045580 83 0.012
regulation of neuron projection development GO:0010975 169 0.012
regulation of stem cell proliferation GO:0072091 78 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
extracellular structure organization GO:0043062 148 0.012
meiotic cell cycle process GO:1903046 77 0.012
response to insulin GO:0032868 100 0.012
negative regulation of neuron differentiation GO:0045665 101 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
metal ion homeostasis GO:0055065 189 0.012
epithelial cell development GO:0002064 159 0.012
positive regulation of epithelial cell proliferation GO:0050679 68 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
regulation of histone methylation GO:0031060 30 0.012
regulation of cell size GO:0008361 72 0.012
leukocyte proliferation GO:0070661 172 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
cell differentiation in spinal cord GO:0021515 53 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
male gonad development GO:0008584 88 0.012
somatic cell dna recombination GO:0016444 51 0.012
angiogenesis GO:0001525 201 0.012
neural tube development GO:0021915 160 0.012
regulation of protein localization GO:0032880 231 0.011
cytokine biosynthetic process GO:0042089 68 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
gonad development GO:0008406 141 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
pallium development GO:0021543 120 0.011
mitotic sister chromatid cohesion GO:0007064 1 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
regulation of cell cycle g2 m phase transition GO:1902749 10 0.011
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
epithelial tube formation GO:0072175 130 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
regulation of cell projection organization GO:0031344 206 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of cell cycle g1 s phase transition GO:1902806 35 0.011
gtp catabolic process GO:0006184 143 0.011
spinal cord development GO:0021510 81 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
negative regulation of molecular function GO:0044092 258 0.011
digestive tract morphogenesis GO:0048546 147 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
hormone secretion GO:0046879 128 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
epithelial cell proliferation GO:0050673 174 0.011
neuronal action potential GO:0019228 54 0.011
regulation of ion transport GO:0043269 215 0.011
positive regulation of transferase activity GO:0051347 167 0.011
peptide hormone secretion GO:0030072 109 0.011
organic acid biosynthetic process GO:0016053 86 0.011
sequestering of calcium ion GO:0051208 18 0.011
macromolecule methylation GO:0043414 120 0.011
t cell differentiation in thymus GO:0033077 77 0.011
embryonic appendage morphogenesis GO:0035113 126 0.011
cation homeostasis GO:0055080 212 0.011
b cell activation involved in immune response GO:0002312 50 0.011
response to light stimulus GO:0009416 135 0.010
response to lipopolysaccharide GO:0032496 128 0.010
lymphocyte apoptotic process GO:0070227 54 0.010
cation transmembrane transport GO:0098655 266 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
negative regulation of dna replication GO:0008156 4 0.010
odontogenesis of dentin containing tooth GO:0042475 66 0.010
somatic diversification of immune receptors GO:0002200 53 0.010
limb morphogenesis GO:0035108 149 0.010
negative regulation of t cell activation GO:0050868 65 0.010
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 3 0.010
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.010
regulation of homeostatic process GO:0032844 182 0.010
cartilage development GO:0051216 140 0.010
detection of molecule of bacterial origin GO:0032490 2 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
protein processing GO:0016485 163 0.010
compound eye development GO:0048749 1 0.010
response to organonitrogen compound GO:0010243 246 0.010
mammary gland epithelium development GO:0061180 65 0.010
myeloid dendritic cell activation GO:0001773 25 0.010
response to transforming growth factor beta GO:0071559 88 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
mesoderm development GO:0007498 100 0.010
mitochondrion organization GO:0007005 134 0.010
neural precursor cell proliferation GO:0061351 121 0.010

Fanca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.043
immune system disease DOID:2914 0 0.029
Human
disease of anatomical entity DOID:7 0 0.029
Human
hematopoietic system disease DOID:74 0 0.019
Human
reproductive system disease DOID:15 0 0.018
congenital hypoplastic anemia DOID:1342 0 0.013
Human
aplastic anemia DOID:12449 0 0.013
Human
bone marrow disease DOID:4961 0 0.013
Human
anemia DOID:2355 0 0.013
Human
female reproductive system disease DOID:229 0 0.011
ovarian disease DOID:1100 0 0.011
large intestine cancer DOID:5672 0 0.010
gastrointestinal system cancer DOID:3119 0 0.010
intestinal cancer DOID:10155 0 0.010