Mus musculus

0 known processes

Fancm

Fanconi anemia, complementation group M

(Aliases: AI427100,D12Ertd364e,C730036B14Rik)

Fancm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle process GO:1903046 77 0.541
Human
meiosis i GO:0007127 60 0.363
Human
cellular response to dna damage stimulus GO:0006974 207 0.273
Human
dna repair GO:0006281 107 0.272
dna metabolic process GO:0006259 303 0.242
Human
dna recombination GO:0006310 92 0.213
Human
nuclear division GO:0000280 158 0.194
Human
microtubule cytoskeleton organization GO:0000226 157 0.145
meiotic nuclear division GO:0007126 115 0.142
Human
meiotic cell cycle GO:0051321 122 0.117
Human
regulation of cellular amine metabolic process GO:0033238 20 0.116
microtubule based process GO:0007017 236 0.114
regulation of cellular ketone metabolic process GO:0010565 66 0.109
organelle fission GO:0048285 170 0.098
Human
regulation of organelle organization GO:0033043 289 0.090
organelle assembly GO:0070925 177 0.083
mitotic cell cycle GO:0000278 195 0.082
cellular amino acid metabolic process GO:0006520 103 0.080
regulation of cellular amino acid metabolic process GO:0006521 5 0.079
cellular amine metabolic process GO:0044106 44 0.075
amine metabolic process GO:0009308 45 0.073
double strand break repair GO:0006302 48 0.071
cellular ketone metabolic process GO:0042180 84 0.066
mitotic cell cycle process GO:1903047 159 0.065
negative regulation of cellular component organization GO:0051129 194 0.062
male meiosis i GO:0007141 16 0.055
aromatic compound catabolic process GO:0019439 286 0.053
heterocycle catabolic process GO:0046700 280 0.051
regulation of cell cycle GO:0051726 281 0.049
peptidyl amino acid modification GO:0018193 336 0.049
organic cyclic compound catabolic process GO:1901361 295 0.048
chromatin organization GO:0006325 206 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.042
b cell activation GO:0042113 161 0.039
macromolecule catabolic process GO:0009057 281 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
regulation of chromosome organization GO:0033044 83 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.036
male meiosis GO:0007140 37 0.035
histone modification GO:0016570 159 0.035
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
leukocyte differentiation GO:0002521 342 0.034
dna replication GO:0006260 52 0.034
Human
microtubule organizing center organization GO:0031023 28 0.033
microtubule nucleation GO:0007020 2 0.033
negative regulation of organelle organization GO:0010639 90 0.032
ribonucleotide catabolic process GO:0009261 208 0.032
telomere capping GO:0016233 4 0.032
gland development GO:0048732 330 0.032
regulation of cell division GO:0051302 76 0.031
dna conformation change GO:0071103 37 0.030
regulation of cell cycle process GO:0010564 160 0.030
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.029
Human
negative regulation of cell cycle phase transition GO:1901988 48 0.029
regulation of cell activation GO:0050865 289 0.029
chromosome organization involved in meiosis GO:0070192 39 0.029
macromolecule methylation GO:0043414 120 0.029
negative regulation of cell cycle process GO:0010948 69 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
double strand break repair via homologous recombination GO:0000724 21 0.028
mitotic chromosome condensation GO:0007076 1 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
positive regulation of protein modification process GO:0031401 299 0.028
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.028
response to organonitrogen compound GO:0010243 246 0.028
male gamete generation GO:0048232 285 0.027
spermatogenesis GO:0007283 284 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
cell activation involved in immune response GO:0002263 126 0.026
spindle organization GO:0007051 28 0.025
cell division GO:0051301 120 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
glycosyl compound catabolic process GO:1901658 206 0.024
purine containing compound metabolic process GO:0072521 311 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
cellular protein complex assembly GO:0043623 116 0.023
wnt signaling pathway GO:0016055 188 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
nitrogen compound transport GO:0071705 271 0.022
actin cytoskeleton organization GO:0030036 220 0.022
centrosome organization GO:0051297 26 0.022
apoptotic signaling pathway GO:0097190 306 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
dna catabolic process endonucleolytic GO:0000737 15 0.022
purine nucleotide catabolic process GO:0006195 211 0.021
establishment of organelle localization GO:0051656 122 0.021
reciprocal dna recombination GO:0035825 16 0.021
Human
nucleoside phosphate metabolic process GO:0006753 338 0.021
multicellular organism growth GO:0035264 161 0.021
protein methylation GO:0006479 81 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
chromosome segregation GO:0007059 48 0.020
Human
somatic cell dna recombination GO:0016444 51 0.020
metaphase plate congression GO:0051310 2 0.020
development of primary sexual characteristics GO:0045137 143 0.020
nucleoside catabolic process GO:0009164 206 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
regulation of mitosis GO:0007088 29 0.020
t cell activation GO:0042110 289 0.020
regulation of t cell activation GO:0050863 170 0.020
cytokine production GO:0001816 319 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
production of molecular mediator of immune response GO:0002440 103 0.019
purine containing compound catabolic process GO:0072523 213 0.019
protein catabolic process GO:0030163 221 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
organophosphate catabolic process GO:0046434 232 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
anatomical structure homeostasis GO:0060249 145 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
lymphocyte differentiation GO:0030098 242 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
negative regulation of cell division GO:0051782 24 0.019
cell cycle checkpoint GO:0000075 47 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
negative regulation of nuclear division GO:0051784 19 0.019
positive regulation of wnt signaling pathway GO:0030177 45 0.018
nucleoside metabolic process GO:0009116 246 0.018
methylation GO:0032259 134 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
skeletal system development GO:0001501 356 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
regulation of protein catabolic process GO:0042176 108 0.018
negative regulation of cell cycle GO:0045786 123 0.018
germ cell development GO:0007281 185 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
nucleotide metabolic process GO:0009117 332 0.018
positive regulation of cell cycle GO:0045787 92 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
negative regulation of synapse assembly GO:0051964 3 0.018
positive regulation of cell development GO:0010720 237 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
organelle localization GO:0051640 179 0.017
respiratory system development GO:0060541 190 0.017
immunoglobulin production GO:0002377 73 0.017
regulation of cytokine production GO:0001817 266 0.017
cell type specific apoptotic process GO:0097285 268 0.017
maintenance of location GO:0051235 89 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
dna dependent dna replication GO:0006261 24 0.017
Human
female meiotic division GO:0007143 21 0.017
mitotic recombination GO:0006312 3 0.016
positive regulation of cell death GO:0010942 224 0.016
regulation of cell cycle phase transition GO:1901987 77 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
histone lysine methylation GO:0034968 50 0.016
ras protein signal transduction GO:0007265 77 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
regulation of protein localization GO:0032880 231 0.016
heterochromatin organization GO:0070828 4 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
locomotory behavior GO:0007626 195 0.016
immune effector process GO:0002252 321 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.015
dna endoreduplication GO:0042023 4 0.015
regulation of hydrolase activity GO:0051336 246 0.015
protein polymerization GO:0051258 57 0.015
rho protein signal transduction GO:0007266 32 0.015
organism emergence from protective structure GO:0071684 4 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
nuclear transport GO:0051169 139 0.015
embryonic placenta development GO:0001892 98 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
female meiosis chromosome segregation GO:0016321 1 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
actin filament organization GO:0007015 113 0.015
sensory perception GO:0007600 245 0.015
nucleotide catabolic process GO:0009166 217 0.015
membrane organization GO:0061024 245 0.015
compound eye development GO:0048749 1 0.015
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.015
response to insulin GO:0032868 100 0.014
leukocyte mediated immunity GO:0002443 174 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
protein maturation GO:0051604 176 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
endocytosis GO:0006897 168 0.014
leukocyte proliferation GO:0070661 172 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
placenta development GO:0001890 140 0.014
regulation of neuron differentiation GO:0045664 281 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
positive regulation of transferase activity GO:0051347 167 0.014
gonad development GO:0008406 141 0.014
tissue homeostasis GO:0001894 115 0.014
multi multicellular organism process GO:0044706 109 0.014
dna packaging GO:0006323 30 0.014
protein ubiquitination GO:0016567 171 0.014
positive regulation of nervous system development GO:0051962 221 0.014
somatic diversification of immune receptors GO:0002200 53 0.014
dna biosynthetic process GO:0071897 22 0.014
ossification GO:0001503 216 0.014
blood vessel morphogenesis GO:0048514 285 0.014
negative regulation of cell proliferation GO:0008285 296 0.013
chromatin modification GO:0016568 187 0.013
cognition GO:0050890 149 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
lymphocyte proliferation GO:0046651 164 0.013
camera type eye development GO:0043010 266 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
b cell differentiation GO:0030183 78 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
regulation of transferase activity GO:0051338 263 0.013
cilium morphogenesis GO:0060271 102 0.013
histone methylation GO:0016571 71 0.013
respiratory tube development GO:0030323 167 0.013
regulation of cell projection organization GO:0031344 206 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
cell growth GO:0016049 130 0.013
somatic diversification of immunoglobulins GO:0016445 43 0.013
cellular homeostasis GO:0019725 240 0.013
synapsis GO:0007129 34 0.013
regulation of nuclear division GO:0051783 56 0.013
attachment of spindle microtubules to kinetochore GO:0008608 4 0.013
female gamete generation GO:0007292 74 0.013
protein alkylation GO:0008213 81 0.013
cell maturation GO:0048469 127 0.013
regulation of proteolysis GO:0030162 164 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
meiotic chromosome segregation GO:0045132 19 0.012
Human
positive regulation of glial cell proliferation GO:0060252 4 0.012
organic acid biosynthetic process GO:0016053 86 0.012
cellular chemical homeostasis GO:0055082 215 0.012
cellular response to peptide GO:1901653 92 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of homeostatic process GO:0032844 182 0.012
regulation of translation GO:0006417 71 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
regulation of kinase activity GO:0043549 249 0.012
regulation of cell migration GO:0030334 219 0.012
negative regulation of immune system process GO:0002683 209 0.012
negative regulation of nervous system development GO:0051961 156 0.012
regulation of hormone levels GO:0010817 211 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
lung development GO:0030324 164 0.012
fertilization GO:0009566 127 0.012
developmental maturation GO:0021700 193 0.012
regulation of secretion GO:0051046 274 0.012
cytoplasmic transport GO:0016482 234 0.012
cell adhesion GO:0007155 329 0.012
intra s dna damage checkpoint GO:0031573 4 0.012
embryonic organ morphogenesis GO:0048562 276 0.011
intracellular protein transport GO:0006886 204 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
regulation of cell cycle g2 m phase transition GO:1902749 10 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
determination of left right symmetry GO:0007368 80 0.011
positive regulation of cell activation GO:0050867 158 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
regulation of histone modification GO:0031056 56 0.011
multicellular organismal signaling GO:0035637 91 0.011
carbohydrate homeostasis GO:0033500 128 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
response to light stimulus GO:0009416 135 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
mrna metabolic process GO:0016071 84 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
innate immune response GO:0045087 157 0.011
endomembrane system organization GO:0010256 147 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
double strand break repair via nonhomologous end joining GO:0006303 10 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
mitotic nuclear division GO:0007067 48 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
digestive system development GO:0055123 200 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.011
telencephalon development GO:0021537 186 0.011
mitochondrion organization GO:0007005 134 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
small molecule biosynthetic process GO:0044283 132 0.011
cellular protein catabolic process GO:0044257 155 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
regulation of canonical wnt signaling pathway GO:0060828 82 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
blastocyst development GO:0001824 80 0.010
single fertilization GO:0007338 82 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
response to organic cyclic compound GO:0014070 198 0.010
adaptive immune response GO:0002250 155 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.010
regulation of binding GO:0051098 111 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
spermatid development GO:0007286 108 0.010
oogenesis GO:0048477 56 0.010
t cell differentiation GO:0030217 174 0.010
urogenital system development GO:0001655 261 0.010
receptor mediated endocytosis GO:0006898 51 0.010
maintenance of location in cell GO:0051651 24 0.010
telomere maintenance GO:0000723 19 0.010
regulation of t cell proliferation GO:0042129 92 0.010
regulation of protein complex assembly GO:0043254 83 0.010
regulation of secretion by cell GO:1903530 249 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010

Fancm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.044
Human
disease of anatomical entity DOID:7 0 0.044
Human
hematopoietic system disease DOID:74 0 0.044
Human
congenital hypoplastic anemia DOID:1342 0 0.020
Human
aplastic anemia DOID:12449 0 0.020
Human
bone marrow disease DOID:4961 0 0.020
Human
anemia DOID:2355 0 0.020
Human
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011